| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karin Leslie, Guy StJ Whitley, Florian Herse, Ralf Dechend, Sandra V Ashton, Ken Laing, Baskaran Thilaganathan, Judith E Cartwrigh. Increased apoptosis, altered oxygen signaling, and antioxidant defenses in first-trimester pregnancies with high-resistance uterine artery blood flow. The American journal of pathology. vol 185. issue 10. 2016-05-03. PMID:26362067. |
apoptosis was significantly higher in high ri placental tissue, as determined by western blot analysis of cleaved poly (adp-ribose) polymerase and caspase 3. |
2016-05-03 |
2023-08-13 |
Not clear |
| Han Liao, Xinran Bao, Jie Zhu, Jiao Qu, Yong Sun, Xiaodong Ma, Enxia Wang, Xin Guo, Qi Kang, Yuhong Zhe. O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway. Chemico-biological interactions. vol 242. 2016-05-03. PMID:26415619. |
western blot assay showed that endonuclease g and apoptosis inducing factor might be relative to the apoptosis. |
2016-05-03 |
2023-08-13 |
human |
| Prasun Patra, Shouvik Mitra, Amarto Das Gupta, Saheli Pradhan, Saurav Bhattacharya, Manisha Ahir, Sudeshna Mukherjee, Sampad Sarkar, Subhrodeb Roy, Sreya Chattopadhyay, Arghya Adhikary, Arunava Goswami, Dhrubajyoti Chattopadhya. Simple synthesis of biocompatible biotinylated porous hexagonal ZnO nanodisc for targeted doxorubicin delivery against breast cancer cell: In vitro and in vivo cytotoxic potential. Colloids and surfaces. B, Biointerfaces. vol 133. 2016-05-02. PMID:26093304. |
a detailed in vitro cytotoxicity study was associated with it to evaluate the mode of action of dox loaded pzhd on mcf-7 cells by means of cell cycle analysis, apoptosis assays, western blot and immuno-fluorescence image analysis. |
2016-05-02 |
2023-08-13 |
Not clear |
| Chan Chen, Jingjing Cai, Shu Zhang, Lu Gan, Yuanlin Dong, Tao Zhu, Gang Ma, Tao Li, Xiyang Zhang, Qian Li, Xu Cheng, Chaomeng Wu, Jing Yang, Yunxia Zuo, Jin Li. Protective Effect of RNase on Unilateral Nephrectomy-Induced Postoperative Cognitive Dysfunction in Aged Mice. PloS one. vol 10. issue 7. 2016-05-02. PMID:26225860. |
we found that perioperative administration of rnase: 1) attenuated unilateral nephrectomy-induced cognitive impairment at day 3 after surgery; 2) reduced the hippocampal cytokines mrna production and serum cytokines protein production at day 1 and day 7 (for mcp-1) after surgery, and; 3) inhibited hippocampal apoptosis as indicated by cleaved caspase-3 western blot and tunel staining at day 1 after surgery. |
2016-05-02 |
2023-08-13 |
mouse |
| B C Simsek, B A Turk, F Ozen, M Tuzcu, M Kante. Investigation of telomerase activity and apoptosis on invasive ductal carcinoma of the breast using immunohistochemical and Western blot methods. European review for medical and pharmacological sciences. vol 19. issue 16. 2016-05-02. PMID:26367733. |
investigation of telomerase activity and apoptosis on invasive ductal carcinoma of the breast using immunohistochemical and western blot methods. |
2016-05-02 |
2023-08-13 |
Not clear |
| B C Simsek, B A Turk, F Ozen, M Tuzcu, M Kante. Investigation of telomerase activity and apoptosis on invasive ductal carcinoma of the breast using immunohistochemical and Western blot methods. European review for medical and pharmacological sciences. vol 19. issue 16. 2016-05-02. PMID:26367733. |
this study aimed to investigate telomerase activity and apoptosis using immunohistochemical and western blot methods. |
2016-05-02 |
2023-08-13 |
Not clear |
| Yan-Qin Zhu, Bai-Yan Wang, Fang Wu, Yong-Kang An, Xin-Qiang Zho. Influence of Tanshinone IIA on the Apoptosis of Human Esophageal Ec-109 Cells. Natural product communications. vol 11. issue 1. 2016-05-02. PMID:26996008. |
the apoptosis rate was detected by the ao/eb and annexin v-fitc/propidium iodide assay, and the protein levels of caspase-4 and chop were determined by the western blot technique. |
2016-05-02 |
2023-08-13 |
human |
| Qin-Ying Liu, Tong Zhou, Yang-Yang Zhao, Li Chen, Mei-Wei Gong, Qi-Wen Xia, Min-Gang Ying, Qiu-Hong Zheng, Qi-Qing Zhan. Antitumor Effects and Related Mechanisms of Penicitrinine A, a Novel Alkaloid with a Unique Spiro Skeleton from the Marine Fungus Penicillium citrinum. Marine drugs. vol 13. issue 8. 2016-04-28. PMID:26264002. |
morphologic evaluation, apoptosis rate analysis, western blot and real-time quantitative pcr (rt-qpcr) results showed penicitrinine a could significantly induce a-375 cell apoptosis by decreasing the expression of bcl-2 and increasing the expression of bax. |
2016-04-28 |
2023-08-13 |
human |
| Ling-Yen Chiu, Ming-E Hu, Tsung-Ying Yang, I-Lun Hsin, Jiunn-Liang Ko, Kan-Jen Tsai, Gwo-Tarng She. Immunomodulatory Protein from Ganoderma microsporum Induces Pro-Death Autophagy through Akt-mTOR-p70S6K Pathway Inhibition in Multidrug Resistant Lung Cancer Cells. PloS one. vol 10. issue 5. 2016-04-25. PMID:25946033. |
tg- and tm-mediated apoptosis of mdr sublines was demonstrated on annexin-v assay and western blot and repressed by pan-caspase inhibitor (z-vad-fmk). |
2016-04-25 |
2023-08-13 |
mouse |
| Qing-Bo Zhou, Qing Jia, Yuan Zhang, Lu-Yang Li, Zhao-Fu Chi, Ping Li. "Effects of baicalin on protease-activated receptor-1 expression and brain injury in a rat model of intracerebral hemorrhage". The Chinese journal of physiology. vol 55. issue 3. 2016-04-23. PMID:22784286. |
brain water content was analyzed by desiccation method; mrna and protein levels of brain protease-activated receptor-1 (par-1) were determined by rt-pcr and western blot, respectively; cell apoptosis was evaluated by terminal transferase dutp nick end labeling staining. |
2016-04-23 |
2023-08-12 |
rat |
| Nan Wu, Xiaowen Zhang, Pengyu Jia, Dalin Ji. Hypercholesterolemia aggravates myocardial ischemia reperfusion injury via activating endoplasmic reticulum stress-mediated apoptosis. Experimental and molecular pathology. vol 99. issue 3. 2016-04-22. PMID:26318286. |
the marker proteins of er stress response and er stress-mediated apoptosis pathway were detected by western blot. |
2016-04-22 |
2023-08-13 |
Not clear |
| Eun-Yi Ko, Seung-Hong Lee, Ji-Yeon Ko, Jeong Yong Moon, Weon-Jong Yoon, Ginnae Ahn, Seong Woon Roh, Kichul Cho, You-Jin Jeon, Daekyung Kim, Kil-Nam Ki. Trans-1,3-diphenyl-2,3-epoxypropan-1-one, a chalcone derivative, induces apoptosis via ROS-mediated down-regulation of Bcl-xL in human leukemia HL-60 cells. EXCLI journal. vol 14. 2016-04-22. PMID:27103891. |
western blot analysis revealed that dpep inhibits bcl-xl expression, leading to caspase-3 activation and poly-adp-ribose polymerase (parp) cleavage, thereby inducing apoptosis. |
2016-04-22 |
2023-08-13 |
human |
| Min Xiao, Jin Wang, Zongtao Lin, Yan Lu, Zhenmei Li, Stephen W White, Duane D Miller, Wei L. Design, Synthesis and Structure-Activity Relationship Studies of Novel Survivin Inhibitors with Potent Anti-Proliferative Properties. PloS one. vol 10. issue 6. 2016-04-21. PMID:26070194. |
the results indicated that structural modification from uc-112 to our best compound 4g has improved activity by four folds (2.2 μm for uc-112 vs. 0.5 μm for 4g, average gi50 values over all cancer cell lines in the nci-60 panel).western blot analyses demonstrated the new compounds maintained high selectivity for survivin inhibition over other members in the inhibition of apoptosis protein family. |
2016-04-21 |
2023-08-13 |
human |
| Haiyan Zhang, Shaohua Gou, Jian Zhao, Feihong Chen, Gang Xu, Xia Li. Cytotoxicity profile of novel sterically hindered platinum(II) complexes with (1R,2R)-N(1),N(2)-dibutyl-1,2-diaminocyclohexane. European journal of medicinal chemistry. vol 96. 2016-04-20. PMID:25874342. |
western blot analysis showed it had a similar apoptotic mechanism to cisplatin which could induce apoptosis via a mitochondrial-dependent pathway. |
2016-04-20 |
2023-08-13 |
Not clear |
| Josiana A Vaz, Gabriela M Almeida, Isabel C F R Ferreira, Anabela Martins, M Helena Vasconcelo. Clitocybe alexandri extract induces cell cycle arrest and apoptosis in a lung cancer cell line: Identification of phenolic acids with cytotoxic potential. Food chemistry. vol 132. issue 1. 2016-04-18. PMID:26434319. |
the effects on cell cycle profile and levels of apoptosis were evaluated by flow cytometry, and the effect on the expression levels of proteins related to cellular apoptosis was also investigated by western blot. |
2016-04-18 |
2023-08-13 |
Not clear |
| Seulki Lee, Hwan Hee Lee, Jisung Kim, Joohee Jung, Aree Moon, Choon-Sik Jeong, Hyojeung Kang, Hyosun Ch. Anti-tumor effect of Cordyceps militaris in HCV-infected human hepatocarcinoma 7.5 cells. Journal of microbiology (Seoul, Korea). vol 53. issue 7. 2016-04-15. PMID:26115996. |
to examine the molecular mechanisms of the inhibitory effect on huh7.5 cells, the effect of cme on cell apoptosis was measured using flow cytometry and the expressions of p53, bim, bax, parp, (cleaved) caspase-9, and (cleaved) caspase- 3 in huh 7.5 cells were detected by western blot assays. |
2016-04-15 |
2023-08-13 |
human |
| Juan Xiao, Chunmei Jin, Zhixue Liu, Shujing Guo, Xiaochuan Zhang, Xin Zhou, Xue W. The design, synthesis, and biological evaluation of novel YC-1 derivatives as potent anti-hepatic fibrosis agents. Organic & biomolecular chemistry. vol 13. issue 26. 2016-04-13. PMID:26055070. |
moreover, the possible underlying mechanism of anti-fibrotic activity was also investigated for the first time by means of a cck-8 assay, cell apoptosis analysis, and western blot analysis. |
2016-04-13 |
2023-08-13 |
human |
| Juan Xiao, Chunmei Jin, Zhixue Liu, Shujing Guo, Xiaochuan Zhang, Xin Zhou, Xue W. The design, synthesis, and biological evaluation of novel YC-1 derivatives as potent anti-hepatic fibrosis agents. Organic & biomolecular chemistry. vol 13. issue 26. 2016-04-13. PMID:26055070. |
western blot data demonstrated that these derivatives not only decreased the expression of α-smooth muscle actin (α-sma), but also increased the expression of caspase-3, resulting in cell apoptosis. |
2016-04-13 |
2023-08-13 |
human |
| Anjun Yao, Yingzhuo Shen, Anshi Wang, Shiyong Chen, Huiqin Zhang, Fen Chen, Zhongming Chen, Hua Wei, Zuquan Zou, Yujuan Shan, Xiaohong Zhan. Sulforaphane induces apoptosis in adipocytes via Akt/p70s6k1/Bad inhibition and ERK activation. Biochemical and biophysical research communications. vol 465. issue 4. 2016-04-12. PMID:26296464. |
western blot demonstrated that sfn-induced apoptosis was mediated via the mitochondrial apoptosis pathway based on increased cleavage of poly-adp-ribose-polymerase (parp), release of cytochrome c into the cytoplasm, and activation of caspase-3, as well as decreased bcl-2/bax ratio. |
2016-04-12 |
2023-08-13 |
Not clear |
| Yu Chen, Wen Wang, Fen Liu, Luosheng Tang, Renhong Tang, Wenjie L. 9-cis-retinoic acid improves sensitivity to platelet-derived growth factor-BB via RXRα and SHP-1 in diabetic retinopathy. Biochemical and biophysical research communications. vol 465. issue 4. 2016-04-12. PMID:26310807. |
using streptozotocin (stz)-induced diabetic mice and high glucose-treated bovine retinal pericytes (brpc), we analyzed the impacts of 9-cis-ra by detecting cell apoptosis via dna fragmentation assay and detecting related factors through adenovirus or lentivirus infection and western blot. |
2016-04-12 |
2023-08-13 |
mouse |