| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| QingYun Tan, LiLi Liu, Shuo Wang, QingDong Wang, Yu Su. Dexmedetomidine Promoted HSPB8 Expression via Inhibiting the lncRNA SNHG14/UPF1 Axis to Inhibit Apoptosis of Nerve Cells in AD : The Role of Dexmedetomidine in AD. Neurotoxicity research. 2023-09-01. PMID:37656385. |
cell viability, apoptosis, the level of genes, and proteins were detected by cck-8 assay, flow cytometry, western blot, and qrt-pcr, respectively. dex downregulated lncrna snhg14 level and inhibited apoptosis of nerve cells. |
2023-09-01 |
2023-09-07 |
Not clear |
| Yongzhou Huang, Wenchang Yang, Lei Yang, Tao Wang, Chengguo Li, Jiaxian Yu, Peng Zhang, Yuping Yin, Ruidong Li, Kaixiong Ta. Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis. Scientific reports. vol 13. issue 1. 2023-09-01. PMID:37658132. |
by measuring cell viability, colony formation, apoptosis, reactive oxygen species production, and western blot, we found that oxaliplatin and lobaplatin suppressed the growth of hct-116 and lovo cells in a dose-dependent manner, and promoted the expression of nrf2. |
2023-09-01 |
2023-09-07 |
Not clear |
| Chengbiao Xue, Zhigao Xu, Zhongzhong Liu, Cheng Zeng, Qifa Y. Pachymic acid protects hepatic cells against oxygen-glucose deprivation/reperfusion injury by activating sirtuin 1 to inhibit HMGB1 acetylation and inflammatory signaling. The Chinese journal of physiology. vol 66. issue 4. 2023-08-28. PMID:37635483. |
finally, cell apoptosis was detected by flow cytometry and western blot. |
2023-08-28 |
2023-09-07 |
Not clear |
| Weiqi Xu, Lihong Zhuang, Hongxu Zhu, Anrong Mao, Jiamin Zhou, Lu Wan. TRIM14 Overexpression Induces Chemoresistance and Malignant Behaviors of Hepatocellular Carcinoma Cells by Activating the STAT3/HIF-1α Pathway. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37628777. |
cell counting kit-8 (cck-8) assay, flow cytometry, transwell assay, rt-pcr, western blot, and immunofluorescence were performed to verify the influence of trim14 on cell proliferation, sensitivity to chemotherapy drugs, apoptosis, migration, invasion, and autophagy. |
2023-08-26 |
2023-09-07 |
Not clear |
| Ming-Yue Ma, Qian Wang, Shou-Mei Wang, Xiao-Jun Feng, Zhi-Hong Xian, Shu-Hui Zhan. Wogonin inhibits hepatoma cell proliferation by targeting miR-27b-5p/YWHAZ axis. Journal of biochemical and molecular toxicology. 2023-08-25. PMID:37623816. |
furthermore, the cell cycle, apoptosis and multiple signaling pathway-related molecules were detected by western blot analysis. |
2023-08-25 |
2023-09-07 |
Not clear |
| Melika Katebi, Soheila Rahgozar, Farnoosh Kazemi, Saeideh Rahmani, Somayeh Najafi Dorche. GingerenoneA overcomes dexamethasone resistance by activating apoptosis and inhibiting cell proliferation in pediatric T-ALL cells. Cancer science. 2023-08-24. PMID:37619556. |
the intrinsic and extrinsic apoptosis induction and antiproliferative attribution of gingerenonea were validated by western blot and qpcr. |
2023-08-24 |
2023-09-07 |
Not clear |
| Jae Eun Park, Ji Sook Ha. Scopoletin protects INS-1 pancreatic β cells from glucotoxicity by reducing oxidative stress and apoptosis. Toxicology in vitro : an international journal published in association with BIBRA. 2023-08-24. PMID:37619648. |
western blot analysis and flow cytometric assessment of apoptosis were also carried out. |
2023-08-24 |
2023-09-07 |
Not clear |
| Lin Bai, Yaping Zhang, Changmin Zheng, Shifu Xu, Yining He, Guangqiang Yu, Delun Huang, Yulin Huang, Mingxing Li, Changlong X. Tanshinone IIA protects mouse testes from heat stress injury by inhibiting apoptosis and TGFβ1/Smad2/Smad3 signaling pathway. Cell stress & chaperones. 2023-08-23. PMID:37610501. |
using western blot technology, we found that the hs group upregulated tgfβ1/smad2/smad3 pathway protein expression, causing cell apoptosis, testicular tissue organic lesions, and affecting testicular secretion function. |
2023-08-23 |
2023-09-07 |
mouse |
| Seth Harris, Kyoungtae Ki. Apoptotic pathway protein expression variance in metal oxide and quantum dot treated HeLa cells. microPublication biology. vol 2023. 2023-08-21. PMID:37602282. |
western blot techniques were used to measure protein expression of phosphorylated p53 (ser15), puma, and p21 which are involved in signal transduction of apoptosis. |
2023-08-21 |
2023-09-07 |
Not clear |
| Mengqi Lu, Jingya Ruan, Rui Yu, Ying Zhang, Wei Zhao, Dingshan Yang, Wanxia Wang, Yi Zhang, Tao Wan. Neolignan derivatives from Penthorum chinense with antitumor activity in human colorectal cancer cells by regulating Wnt/β-catenin signaling pathway. Phytochemistry. vol 214. 2023-08-19. PMID:37595774. |
then, functional technologies such as the 5-ethyny1-2'-deoxyridine, wound healing, transwell, and western blot assays indicated that they could significantly inhibit the proliferation of ht29 and lovo cells, promote apoptosis by up-regulating bax, and down-regulating b-cell cll/lymphoma 2 and poly adp-ribose polymerase. |
2023-08-19 |
2023-09-07 |
human |
| Fang Wang, Yinghong Yu, Gongjian He, Zhangxia Ren, Sizhe X. Downregulation of miR-4284 can inhibit the apoptosis of Human Arterial Smooth Muscle Cells (HASMCs) in arteriosclerosis obliterans (ASO). Combinatorial chemistry & high throughput screening. 2023-08-18. PMID:37594113. |
a western blot technique was used to identify b cell lymphoma-2 (bcl2), bcl2-associated x protein (bax), as well as x-linked inhibitors of apoptosis protein (xiap). |
2023-08-18 |
2023-09-07 |
human |
| Huaibin Sun, Zhiguo Peng, Kao Liu, Shengli Li. Norepinephrine alleviates cyclosporin A-induced nephrotoxicity by enhancing the expression of SFRP1. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-08-17. PMID:37588659. |
the effect of csa (1.25, 2.5, 5, and 10 μm) on the human renal epithelial cell vitality, lactate dehydrogenase (ldh) activity, apoptosis, and secreted frizzled-related protein 1 (sfrp1) level was examined by cell counting kit-8, enzyme-linked immunosorbent assay, flow cytometer, and western blot. |
2023-08-17 |
2023-09-07 |
human |
| Chan Yang, Hanyu Liu, Ziyan Xie, Qiangfei Yang, Lian Du, Chunguang Xi. The protective role of shenqi compound in type 2 diabetes: A comprehensive investigation of pancreatic β-cell function and mass. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 166. 2023-08-12. PMID:37572639. |
the results demonstrate multiple beneficial effects of sqc, including significant control of blood glucose levels (p < 0.05), inhibition of insulin resistance (measured by western blot), reduction of hyperinsulinemia (p < 0.05), attenuation of oxidative stress (p < 0.05), suppression of inflammation (p < 0.05), protection against islet hypertrophy and beta cell proliferation (evaluated through pathological staining), and inhibition of β-cell apoptosis and senescence (also assessed through pathological staining). |
2023-08-12 |
2023-08-16 |
rat |
| Jiayang Yin, Feng Zhang, Jiamin Cao, Zhaochangci Chen, Wei Xion. Gentiopicroside inhibits retinoblastoma cell proliferation, invasion, and tumorigenesis in nude mice by suppressing the PI3K/AKT pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2023-08-09. PMID:37555853. |
the effect and mechanism of gps on growth, apoptosis, invasion, and emt were determined by cell counting kit-8 (cck-8), western blot, flow cytometry, and transwell assays in retinoblastoma cells. |
2023-08-09 |
2023-08-16 |
mouse |
| Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wan. Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway. European journal of histochemistry : EJH. vol 67. issue 3. 2023-08-07. PMID:37548240. |
after cells were treated with 5-fu (10, 40 μg/ml), que (10 μm, 40 μm), or 5-fu in combination with que, cell proliferation, apoptosis, oxidative stress-related factors, reactive oxygen species (ros), and nuclear factor erythroid 2-related factor (nrf2)/heme oxygenase-1 (ho-1) pathway-related factors were examined by colony formation assay, flow cytometry, elisa, ros kit, immunofluorescence assay, and western blot. |
2023-08-07 |
2023-08-14 |
cat |
| Qian Liu, Yuyang Wu, Sisi Li, Somy Yoon, Jiaxin Zhang, Xiaoyi Wang, Luoshuang Hu, Chenying Su, Chunwu Zhang, Yungang W. Ursolic acid alleviates steroid-induced avascular necrosis of the femoral head in mouse by inhibiting apoptosis and rescuing osteogenic differentiation. Toxicology and applied pharmacology. 2023-08-03. PMID:37536651. |
moreover, the results of western blot and tunel experiments showed that ua could delay the disease progression of sanfh in mice by inhibiting apoptosis. |
2023-08-03 |
2023-08-14 |
mouse |
| Nunzio Antonio Cacciola, Fabrizia Sepe, Salvatore Fioriniello, Orsolina Petillo, Sabrina Margarucci, Marcello Scivicco, Gianfranco Peluso, Anna Balestrieri, Giovanna Bifulco, Brunella Restucci, Lorella Severin. The Carnitine Palmitoyltransferase 1A Inhibitor Teglicar Shows Promising Antitumour Activity against Canine Mammary Cancer Cells by Inducing Apoptosis. Pharmaceuticals (Basel, Switzerland). vol 16. issue 7. 2023-07-29. PMID:37513899. |
the expression of mediators of apoptosis signalling (e.g., caspase-9, caspase-8, and caspase-3) was assessed by quantitative real-time polymerase chain reaction and western blot analyses. |
2023-07-29 |
2023-08-14 |
Not clear |
| Muhammad Shoaib Khan, Chunliang Liu, Fanbi Meng, Mengnan Yang, Kangxi Zhou, Renping Hu, Xuexiang Wang, Kesheng Da. X-rays Stimulate Granular Secretions and Activate Protein Kinase C Signaling in Human Platelets. Current issues in molecular biology. vol 45. issue 7. 2023-07-28. PMID:37504296. |
flow cytometry, aggregometry, and western blot were performed to investigate the effect of x-rays on platelet degranulation, integrin activation, platelet aggregation, and apoptosis. |
2023-07-28 |
2023-08-14 |
human |
| Yiwen Zang, Chen Yang, Meng-Shi Dai, Wenye Zhang, Lujia Zou, Jimeng Hu, Yun Hu, Chenyang Xu, Rongzong Liu, Hao Wang, Zuquan Xion. Protective Autophagy Attenuates the Cytotoxicity of MTI-31 in Renal Cancer Cells by Activating the ERK Pathway. Applied biochemistry and biotechnology. 2023-07-26. PMID:37493819. |
after treating the rcc cells with the autophagy inhibitor chloroquine (cq), cck8 and western blot assays demonstrated that cq could effectively enhance cell apoptosis induced by mti-31 and that the autophagy induced by mti-31 was cytoprotective. |
2023-07-26 |
2023-08-14 |
Not clear |
| Sema Serter Kocoglu, Ceren Oy, Mücahit Secme, F Bahar Suna. Investigation of the anticancer mechanism of monensin via apoptosis-related factors in SH-SY5Y neuroblastoma cells. Clinical and translational science. 2023-07-21. PMID:37477356. |
the effects of monensin on apoptosis were determined by rt-pcr, tunel, western blot, and annexin v assay. |
2023-07-21 |
2023-08-14 |
Not clear |