| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiusheng Guo, Yuan Yu, Wanfen Tang, Shishi Zhou, Xianmei L. Matrine exerts an anti-tumor effect via regulating HN1 in triple breast cancer both in vitro and in vivo. Chemical biology & drug design. 2023-09-07. PMID:37674344. |
western blot analysis was applied to detect the protein expression of apoptosis hn1. |
2023-09-07 |
2023-10-07 |
Not clear |
| Mohammad Abdelwahab, Hesham Saeed, Nefertiti Elnikhely, Hisham Nematall. Synergistic effect of Dactolisib/Lys05 combination on autophagy in A549 cells. Acta biochimica Polonica. 2023-09-07. PMID:37677845. |
these effects were corroborated by elisa, western blot, and flow cytometry using the annexin v-fitc apoptosis detection kit. |
2023-09-07 |
2023-10-07 |
Not clear |
| Luwen Zhang, Wenjuan Tang, Yinan Ouyang, Miao Zhang, Ruirui Li, Lianping Sun, Chao Liu, Hailing Y. N-palmitoylethanolamine modulates hippocampal neuroplasticity in rats with stress-induced depressive behavior phenotype. European journal of pharmacology. 2023-09-06. PMID:37673363. |
in vitro, the apoptosis of ht22 cells induced by cort and apoptosis-related proteins were detected by hoechst staining and western blot, respectively. |
2023-09-06 |
2023-10-07 |
rat |
| Huajie Mao, Runzhi Wang, Fengling Shao, Ming Zhao, Dayu Tian, Hua Xia, Ya Zha. HMGCS2 serves as a potential biomarker for inhibition of renal clear cell carcinoma growth. Scientific reports. vol 13. issue 1. 2023-09-05. PMID:37670031. |
finally, the results of cell counting kit 8 assays, colony formation assays, flow cytometry, and western blot analysis suggested that upregulation of hmgcs2 increased the expression of key tumor suppressor proteins, inhibited the proliferation of clear cell renal cell carcinoma cells and promoted cell apoptosis. |
2023-09-05 |
2023-10-07 |
human |
| Alexandra S Kuzmich, Lyudmila A Romanenko, Maxim S Kokouli. Cell-cycle arrest and mitochondria-dependent apoptosis induction in T-47D cells by the capsular polysaccharide from the marine bacterium Kangiella japonica KMM 3897. Carbohydrate polymers. vol 320. 2023-09-02. PMID:37659798. |
flow cytometric and western blot analysis revealed that capsular polysaccharide effectively suppressed t-47d cell proliferation by inducing g0/g1 phase arrest and mitochondrial-dependent apoptosis. |
2023-09-02 |
2023-09-07 |
human |
| QingYun Tan, LiLi Liu, Shuo Wang, QingDong Wang, Yu Su. Dexmedetomidine Promoted HSPB8 Expression via Inhibiting the lncRNA SNHG14/UPF1 Axis to Inhibit Apoptosis of Nerve Cells in AD : The Role of Dexmedetomidine in AD. Neurotoxicity research. 2023-09-01. PMID:37656385. |
cell viability, apoptosis, the level of genes, and proteins were detected by cck-8 assay, flow cytometry, western blot, and qrt-pcr, respectively. dex downregulated lncrna snhg14 level and inhibited apoptosis of nerve cells. |
2023-09-01 |
2023-09-07 |
Not clear |
| Yongzhou Huang, Wenchang Yang, Lei Yang, Tao Wang, Chengguo Li, Jiaxian Yu, Peng Zhang, Yuping Yin, Ruidong Li, Kaixiong Ta. Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis. Scientific reports. vol 13. issue 1. 2023-09-01. PMID:37658132. |
by measuring cell viability, colony formation, apoptosis, reactive oxygen species production, and western blot, we found that oxaliplatin and lobaplatin suppressed the growth of hct-116 and lovo cells in a dose-dependent manner, and promoted the expression of nrf2. |
2023-09-01 |
2023-09-07 |
Not clear |
| Chengbiao Xue, Zhigao Xu, Zhongzhong Liu, Cheng Zeng, Qifa Y. Pachymic acid protects hepatic cells against oxygen-glucose deprivation/reperfusion injury by activating sirtuin 1 to inhibit HMGB1 acetylation and inflammatory signaling. The Chinese journal of physiology. vol 66. issue 4. 2023-08-28. PMID:37635483. |
finally, cell apoptosis was detected by flow cytometry and western blot. |
2023-08-28 |
2023-09-07 |
Not clear |
| Weiqi Xu, Lihong Zhuang, Hongxu Zhu, Anrong Mao, Jiamin Zhou, Lu Wan. TRIM14 Overexpression Induces Chemoresistance and Malignant Behaviors of Hepatocellular Carcinoma Cells by Activating the STAT3/HIF-1α Pathway. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37628777. |
cell counting kit-8 (cck-8) assay, flow cytometry, transwell assay, rt-pcr, western blot, and immunofluorescence were performed to verify the influence of trim14 on cell proliferation, sensitivity to chemotherapy drugs, apoptosis, migration, invasion, and autophagy. |
2023-08-26 |
2023-09-07 |
Not clear |
| Ming-Yue Ma, Qian Wang, Shou-Mei Wang, Xiao-Jun Feng, Zhi-Hong Xian, Shu-Hui Zhan. Wogonin inhibits hepatoma cell proliferation by targeting miR-27b-5p/YWHAZ axis. Journal of biochemical and molecular toxicology. 2023-08-25. PMID:37623816. |
furthermore, the cell cycle, apoptosis and multiple signaling pathway-related molecules were detected by western blot analysis. |
2023-08-25 |
2023-09-07 |
Not clear |
| Melika Katebi, Soheila Rahgozar, Farnoosh Kazemi, Saeideh Rahmani, Somayeh Najafi Dorche. GingerenoneA overcomes dexamethasone resistance by activating apoptosis and inhibiting cell proliferation in pediatric T-ALL cells. Cancer science. 2023-08-24. PMID:37619556. |
the intrinsic and extrinsic apoptosis induction and antiproliferative attribution of gingerenonea were validated by western blot and qpcr. |
2023-08-24 |
2023-09-07 |
Not clear |
| Jae Eun Park, Ji Sook Ha. Scopoletin protects INS-1 pancreatic β cells from glucotoxicity by reducing oxidative stress and apoptosis. Toxicology in vitro : an international journal published in association with BIBRA. 2023-08-24. PMID:37619648. |
western blot analysis and flow cytometric assessment of apoptosis were also carried out. |
2023-08-24 |
2023-09-07 |
Not clear |
| Lin Bai, Yaping Zhang, Changmin Zheng, Shifu Xu, Yining He, Guangqiang Yu, Delun Huang, Yulin Huang, Mingxing Li, Changlong X. Tanshinone IIA protects mouse testes from heat stress injury by inhibiting apoptosis and TGFβ1/Smad2/Smad3 signaling pathway. Cell stress & chaperones. 2023-08-23. PMID:37610501. |
using western blot technology, we found that the hs group upregulated tgfβ1/smad2/smad3 pathway protein expression, causing cell apoptosis, testicular tissue organic lesions, and affecting testicular secretion function. |
2023-08-23 |
2023-09-07 |
mouse |
| Seth Harris, Kyoungtae Ki. Apoptotic pathway protein expression variance in metal oxide and quantum dot treated HeLa cells. microPublication biology. vol 2023. 2023-08-21. PMID:37602282. |
western blot techniques were used to measure protein expression of phosphorylated p53 (ser15), puma, and p21 which are involved in signal transduction of apoptosis. |
2023-08-21 |
2023-09-07 |
Not clear |
| Mengqi Lu, Jingya Ruan, Rui Yu, Ying Zhang, Wei Zhao, Dingshan Yang, Wanxia Wang, Yi Zhang, Tao Wan. Neolignan derivatives from Penthorum chinense with antitumor activity in human colorectal cancer cells by regulating Wnt/β-catenin signaling pathway. Phytochemistry. vol 214. 2023-08-19. PMID:37595774. |
then, functional technologies such as the 5-ethyny1-2'-deoxyridine, wound healing, transwell, and western blot assays indicated that they could significantly inhibit the proliferation of ht29 and lovo cells, promote apoptosis by up-regulating bax, and down-regulating b-cell cll/lymphoma 2 and poly adp-ribose polymerase. |
2023-08-19 |
2023-09-07 |
human |
| Fang Wang, Yinghong Yu, Gongjian He, Zhangxia Ren, Sizhe X. Downregulation of miR-4284 can inhibit the apoptosis of Human Arterial Smooth Muscle Cells (HASMCs) in arteriosclerosis obliterans (ASO). Combinatorial chemistry & high throughput screening. 2023-08-18. PMID:37594113. |
a western blot technique was used to identify b cell lymphoma-2 (bcl2), bcl2-associated x protein (bax), as well as x-linked inhibitors of apoptosis protein (xiap). |
2023-08-18 |
2023-09-07 |
human |
| Huaibin Sun, Zhiguo Peng, Kao Liu, Shengli Li. Norepinephrine alleviates cyclosporin A-induced nephrotoxicity by enhancing the expression of SFRP1. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-08-17. PMID:37588659. |
the effect of csa (1.25, 2.5, 5, and 10 μm) on the human renal epithelial cell vitality, lactate dehydrogenase (ldh) activity, apoptosis, and secreted frizzled-related protein 1 (sfrp1) level was examined by cell counting kit-8, enzyme-linked immunosorbent assay, flow cytometer, and western blot. |
2023-08-17 |
2023-09-07 |
human |
| Chan Yang, Hanyu Liu, Ziyan Xie, Qiangfei Yang, Lian Du, Chunguang Xi. The protective role of shenqi compound in type 2 diabetes: A comprehensive investigation of pancreatic β-cell function and mass. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 166. 2023-08-12. PMID:37572639. |
the results demonstrate multiple beneficial effects of sqc, including significant control of blood glucose levels (p < 0.05), inhibition of insulin resistance (measured by western blot), reduction of hyperinsulinemia (p < 0.05), attenuation of oxidative stress (p < 0.05), suppression of inflammation (p < 0.05), protection against islet hypertrophy and beta cell proliferation (evaluated through pathological staining), and inhibition of β-cell apoptosis and senescence (also assessed through pathological staining). |
2023-08-12 |
2023-08-16 |
rat |
| Jiayang Yin, Feng Zhang, Jiamin Cao, Zhaochangci Chen, Wei Xion. Gentiopicroside inhibits retinoblastoma cell proliferation, invasion, and tumorigenesis in nude mice by suppressing the PI3K/AKT pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2023-08-09. PMID:37555853. |
the effect and mechanism of gps on growth, apoptosis, invasion, and emt were determined by cell counting kit-8 (cck-8), western blot, flow cytometry, and transwell assays in retinoblastoma cells. |
2023-08-09 |
2023-08-16 |
mouse |
| Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wan. Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway. European journal of histochemistry : EJH. vol 67. issue 3. 2023-08-07. PMID:37548240. |
after cells were treated with 5-fu (10, 40 μg/ml), que (10 μm, 40 μm), or 5-fu in combination with que, cell proliferation, apoptosis, oxidative stress-related factors, reactive oxygen species (ros), and nuclear factor erythroid 2-related factor (nrf2)/heme oxygenase-1 (ho-1) pathway-related factors were examined by colony formation assay, flow cytometry, elisa, ros kit, immunofluorescence assay, and western blot. |
2023-08-07 |
2023-08-14 |
cat |