| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qianwen Zhang, Yiyu He, Hao Xu, Yuqiao Zeng, Li Wang, Zengxi Xue, Qingyun Sun, Likun Wan. MicroRNA-181a-5p alleviates acute liver failure in mice by inhibiting HMGB1. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 9. 2023-10-09. PMID:37807324. |
the expression of caspase 3 was detected as the marker of cell apoptosis in alf by immunohistochemistry and western blot. |
2023-10-09 |
2023-10-15 |
mouse |
| Yujia Sun, Tianqi Zhao, Yaoyao Ma, Xinyi Wu, Shuangfeng Chu, Zhangping Yan. Multiple roles of LncRNA-BMNCR on cell proliferation and apoptosis by targeting miR-145/CBFB axis in BMECs. The veterinary quarterly. 2023-10-09. PMID:37807922. |
in bovine mammary epithelial cells, we preformed loss of function experiments to detect changes in cytokine, proliferation and apoptosis by qrt-pcr, western blot, flow cytometry and edu staining. |
2023-10-09 |
2023-10-15 |
cattle |
| Nan Nan, Xiao-Li DU, Miao Chen, Jia-Qi Lu. [Qirong Tablets inhibits apoptosis of ovarian granulosa cells via PI3K/Akt/ HIF-1 signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 17. 2023-10-06. PMID:37802816. |
terminal deoxynucleotidyl transferase-mediated dutp nick end labeling(tunel) assay was used to detect the apoptosis of granulosa cells, and western blot to determine the expression levels of b-cell lymphoma-2(bcl-2), bcl-2-associated x protein(bax), caspase-3, pi3k, akt, and hif-1. |
2023-10-06 |
2023-10-15 |
mouse |
| Hefei Huang, Tianlun Wang, Luopei Wang, Yan Huang, Weili Li, Jin'e Wang, Yuanlang Hu, Zhiyong Zho. Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway. Experimental gerontology. 2023-10-05. PMID:37797916. |
tunel kit was used to detect apoptosis level of cardiomyocyte, and western blot was used to evaluate autophagy-related proteins as well as ampk/mtor/ulk1 pathway-related markers. |
2023-10-05 |
2023-10-07 |
mouse |
| Shi-Wei Liu, Jia-Qiang Luo, Liang-Yu Zhao, Ning-Jing Ou, Chao-Yang, Yu-Xiang Zhang, Hao-Wei Bai, Hong-Fang Sun, Jian-Xiong Zhang, Chen-Cheng Yao, Peng Li, Ru-Hui Tian, Zheng Li, Zi-Jue Zh. scRNA-seq reveals that origin recognition complex subunit 6 regulates mouse spermatogonial cell proliferation and apoptosis via activation of Wnt/β-catenin signaling. Asian journal of andrology. 2023-10-03. PMID:37788012. |
subsequently, 5-ethynyl-2-deoxyuridine (edu) and terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assays, flow cytometry, and western blot were used to evaluate its effects on proliferation and apoptosis. |
2023-10-03 |
2023-10-07 |
mouse |
| Gui-Hong Zhang, Kai Ling Chin, Shi-Yan Yan, Rahmawati Par. Antioxioxidant and antiapoptotic effects of Thymosin β4 in Aβ-induced SH-SY5Y cells via the 5-HTR1A/ERK axis. PloS one. vol 18. issue 10. 2023-10-03. PMID:37788276. |
we performed western blot and flow cytometry to study the apoptosis and standard kits to measure the oxidative stress-associated biomarkers. |
2023-10-03 |
2023-10-07 |
Not clear |
| Xu-Hui Li, Li Liu, Wen-Zhong W. Trans-Anethole Alleviates DSS-Induced Ulcerative Colitis by Remodeling the Intestinal Flora to Regulate Immunity and Bile Acid Metabolism. Mediators of inflammation. vol 2023. 2023-10-02. PMID:37780399. |
to observe the effect of ta on the colon tissue, various investigations were performed, including western blot and immunohistochemistry for intestinal barrier protein expression, tunel staining for apoptosis, western blot, and elisa for inflammation level, flow cytometry for th17/treg, lc-ms for blood bile acid content, gc-ms for blood fatty acid content, and 16s rna for intestinal contents. |
2023-10-02 |
2023-10-07 |
mouse |
| Yaobo Yang, Zhaoyong Yan, Yang Jiao, Weihao Yang, Qi Cui, Sipan Che. Family with sequence similarity 111 member B contributes to tumor growth and metastasis by mediating cell proliferation, invasion, and EMT via transforming acidic coiled-coil protein 3/PI3K/AKT signaling pathway in hepatocellular carcinoma. Environmental toxicology. 2023-10-02. PMID:37782700. |
the impact of fam111b on proliferation, invasion, apoptosis and emt of hcc cells were detected by cck-8, transwell, flow cytometry and western blot assays. |
2023-10-02 |
2023-10-07 |
mouse |
| Jian-Lan Huang, Li Liang, Pei-En Xie, Wei-Liang Sun, Li Wang, Zheng-Wen Ca. Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways. Experimental and therapeutic medicine. vol 26. issue 4. 2023-09-27. PMID:37753296. |
subsequently, the appropriate cub concentration (5 µm) was selected for treatment of crc cells for 48 h. western blot analysis was used to measure the expression levels of ers-related proteins, flow cytometry was used to evaluate apoptosis, the dichlorodihydrofluorescein diacetate fluorescent probe was used to detect reactive oxygen species (ros) production, and the relationship between ros and ers was determined by western blot analysis. |
2023-09-27 |
2023-10-07 |
Not clear |
| Shaoyi Qiao, Wuhe Zhang, Yao Jiang, Yansheng S. Sennoside A induces autophagic death of prostate cancer via inactivation of PI3K/AKT/mTOR axis. Journal of molecular histology. 2023-09-23. PMID:37740843. |
the effects of sa on growth, apoptosis, and autophagy were determined through cck-8, hoechst stain, flow cytometry, western blot, and immunofluorescence examinations. |
2023-09-23 |
2023-10-07 |
mouse |
| Jing Zhang, Qingbo Zhao, Zhihui Xue, Siyi Zhang, Zeyu Ren, Shaokui Chen, Ao Zhou, Hongbo Chen, Yulan Li. Deoxynivalenol induces endoplasmic reticulum stress-associated apoptosis via the IRE1/JNK/CHOP pathway in porcine alveolar macrophage 3D4/21 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-09-22. PMID:37739053. |
our subsequent validation via qpcr and western blot analyses confirmed the attenuation of grp78 and bcl-2, coupled with the upregulation of ire1, chop, jnk, p-jnk, and bax in don-induced cells, indicating the instigation of er stress-associated apoptosis by don. |
2023-09-22 |
2023-10-07 |
Not clear |
| Feng Guo, Yang Luo, GuangYao Ye, WeiJun Tan. Circular RNA METTL15/miR-374a-5p/ESCO2 axis induces colorectal cancer development. Acta biochimica Polonica. 2023-09-16. PMID:37715994. |
cell proliferation was detected by cck-8 and colony formation tests, cell apoptosis and cell cycle were detected by flow cytometry, cell migration and invasion were detected by transwell assay, and protein expression of ki-67, e-cadherin, n-cadherin, and cleaved caspase-3 was detected by western blot. |
2023-09-16 |
2023-10-07 |
Not clear |
| Ping Chen, Yan Cheng, Jing Hu, Rui Fang, Li-Qi Yan. Recombinant CXCL17 Treatment Alleviates Hyperoxia-Induced Lung Apoptosis and Inflammation In Vivo and Vitro by Activating the AKT Pathway: A Possible Therapeutic Approach for Bronchopulmonary Dysplasia. Molecular biotechnology. 2023-09-14. PMID:37710083. |
apoptosis was assessed by tunel staining and western blot. |
2023-09-14 |
2023-10-07 |
mouse |
| Xingfei Huang, Yumeng Wang, Xingyao Li, Feng Yuan, Guangxin Zhou, Dali Men. Triterpenoids from Meehania fargesii with cytotoxic activity. Chemistry & biodiversity. 2023-09-12. PMID:37697440. |
western blot analysis revealed that these compounds activated apoptosis in hct116 cells by promoting the bax protein and inhibiting the bcl-2 protein. |
2023-09-12 |
2023-10-07 |
Not clear |
| Shuai Wang, Zhonghao Cui, Jian Zhu, Peng Zhou, Xianjiao Cao, Xiaolei Li, Yunhan Ma, Qingqing H. Colchicine inhibits the proliferation and promotes the apoptosis of papillary thyroid carcinoma cells likely due to the inhibitory effect on HDAC1. Biochemical and biophysical research communications. vol 679. 2023-09-10. PMID:37690423. |
we then used cck-8, colony formation, mitochondrial membrane potential and apoptosis assays to confirm that colchicine could inhibit the proliferation and promote the apoptosis of ptc cells and verified by rt‒qpcr, western blot, and cellular immunofluorescence assays that colchicine could inhibit the expression of hdac1 in ptc cells. |
2023-09-10 |
2023-10-07 |
Not clear |
| Qiusheng Guo, Yuan Yu, Wanfen Tang, Shishi Zhou, Xianmei L. Matrine exerts an anti-tumor effect via regulating HN1 in triple breast cancer both in vitro and in vivo. Chemical biology & drug design. 2023-09-07. PMID:37674344. |
western blot analysis was applied to detect the protein expression of apoptosis hn1. |
2023-09-07 |
2023-10-07 |
Not clear |
| Mohammad Abdelwahab, Hesham Saeed, Nefertiti Elnikhely, Hisham Nematall. Synergistic effect of Dactolisib/Lys05 combination on autophagy in A549 cells. Acta biochimica Polonica. 2023-09-07. PMID:37677845. |
these effects were corroborated by elisa, western blot, and flow cytometry using the annexin v-fitc apoptosis detection kit. |
2023-09-07 |
2023-10-07 |
Not clear |
| Luwen Zhang, Wenjuan Tang, Yinan Ouyang, Miao Zhang, Ruirui Li, Lianping Sun, Chao Liu, Hailing Y. N-palmitoylethanolamine modulates hippocampal neuroplasticity in rats with stress-induced depressive behavior phenotype. European journal of pharmacology. 2023-09-06. PMID:37673363. |
in vitro, the apoptosis of ht22 cells induced by cort and apoptosis-related proteins were detected by hoechst staining and western blot, respectively. |
2023-09-06 |
2023-10-07 |
rat |
| Huajie Mao, Runzhi Wang, Fengling Shao, Ming Zhao, Dayu Tian, Hua Xia, Ya Zha. HMGCS2 serves as a potential biomarker for inhibition of renal clear cell carcinoma growth. Scientific reports. vol 13. issue 1. 2023-09-05. PMID:37670031. |
finally, the results of cell counting kit 8 assays, colony formation assays, flow cytometry, and western blot analysis suggested that upregulation of hmgcs2 increased the expression of key tumor suppressor proteins, inhibited the proliferation of clear cell renal cell carcinoma cells and promoted cell apoptosis. |
2023-09-05 |
2023-10-07 |
human |
| Alexandra S Kuzmich, Lyudmila A Romanenko, Maxim S Kokouli. Cell-cycle arrest and mitochondria-dependent apoptosis induction in T-47D cells by the capsular polysaccharide from the marine bacterium Kangiella japonica KMM 3897. Carbohydrate polymers. vol 320. 2023-09-02. PMID:37659798. |
flow cytometric and western blot analysis revealed that capsular polysaccharide effectively suppressed t-47d cell proliferation by inducing g0/g1 phase arrest and mitochondrial-dependent apoptosis. |
2023-09-02 |
2023-09-07 |
human |