| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Debarun Roy, Kaushik Das, Subhasish Mondal, Debajit Bhowmick, Souvik Dey, Gopal C Majumder, Biswajit Mukherjee, Debdas Bhattacharyy. Epididymal protein ASF is a D-galactose-specific lectin with apoptotic effect on human breast cancer cell line MCF7. International journal of biological macromolecules. vol 84. 2016-10-20. PMID:26706839. |
the effective anti-adhesive concentration of asf promotes p53 dependent apoptosis in mcf7, which was established by hoechst 33342 staining, dna fragmentation assay, fitc tagged annexin-v flowcytometry and western blot analysis. |
2016-10-20 |
2023-08-13 |
human |
| Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Che. Uvangoletin induces mitochondria-mediated apoptosis in HL-60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances. Oncology reports. vol 35. issue 2. 2016-10-17. PMID:26717974. |
the results of cck-8, flow cytometry and western blot assays indicated that uvangoletin showed the cytotoxic effect on hl-60 cells and induced the apoptosis of hl-60 cells by downregulating the expression levels of anti-apoptotic proteins (survivin, bcl-xl and bcl-2), upregulating the expression levels of pro-apoptotic proteins (smac, bax, bad, c-caspase-3 and c-caspase-9), and promoting the release of cytochrome c from mitochondria to cytoplasm. |
2016-10-17 |
2023-08-13 |
mouse |
| Lei Gao, Zhen Xu, Yan Wang, Bin Sun, Zhicheng Song, Bining Yang, Xu Liu, Yuan Lin, Jinyong Peng, Guozhu Han, Shisheng Wang, Zeyao Tan. Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells. Oncology reports. vol 35. issue 2. 2016-10-17. PMID:26718492. |
furthermore, flow cytometry, transmission electron microscopy, and western blot analysis revealed that the inhibition of cell viability by oa was mediated by triggering the intrinsic apoptosis of gastric cancer cells, and inducing s phase arrest of sgc7901 cells. |
2016-10-17 |
2023-08-13 |
human |
| Ivana Kovačević, Mirjana Popsavin, Goran Benedeković, Vesna Kojić, Dimitar Jakimov, Marko V Rodić, Tatjana Srdić-Rajić, Gordana Bogdanović, Vladimir Divjaković, Velimir Popsavi. Synthesis and antiproliferative activity of goniobutenolides A and B, 5-halogenated crassalactone D derivatives and the corresponding 7-epimers. European journal of medicinal chemistry. vol 108. 2016-10-17. PMID:26720155. |
results of semi-quantitative western blot analysis indicate that the most of synthesized compounds induce apoptosis in a caspase-dependent manner. |
2016-10-17 |
2023-08-13 |
Not clear |
| Shang-Hai Lai, Guang-Bin Jiang, Jun-Hua Yao, Wei Li, Bing-Jie Han, Cheng Zhang, Chuan-Chuan Zeng, Yun-Jun Li. Cytotoxic activity, DNA damage, cellular uptake, apoptosis and western blot analysis of ruthenium(II) polypyridyl complex against human lung decarcinoma A549 cell. Journal of inorganic biochemistry. vol 152. 2016-10-11. PMID:26291582. |
cytotoxic activity, dna damage, cellular uptake, apoptosis and western blot analysis of ruthenium(ii) polypyridyl complex against human lung decarcinoma a549 cell. |
2016-10-11 |
2023-08-13 |
human |
| Faisal Aziz, Xiaoqi Wang, Jiwei Liu, Qiu Ya. Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions. Toxicology in vitro : an international journal published in association with BIBRA. vol 31. 2016-10-11. PMID:26427350. |
we treated the gastric cancer cells with caga followed by rg3, and analyzed their ability to induce apoptosis by evaluating the role of fut4 as well as sp1 and hsf1 expressions by western blot, flow cytometry and elisa. |
2016-10-11 |
2023-08-13 |
Not clear |
| Xiao-Min Yao, Yue Li, Hong-Wei Li, Xiao-Yan Cheng, Ai-Bin Lin, Jun-Ge Q. Bicyclol attenuates tetracycline-induced fatty liver associated with inhibition of hepatic ER stress and apoptosis in mice. Canadian journal of physiology and pharmacology. vol 94. issue 1. 2016-10-11. PMID:26640164. |
moreover, hepatic apoptosis and er stress related markers were determined by tunel, real-time pcr, and western blot. |
2016-10-11 |
2023-08-13 |
mouse |
| Yi Shi, Lin Sun, Ge Chen, Dongyan Zheng, Li Li, Wanguo We. A combination of the telomerase inhibitor, BIBR1532, and paclitaxel synergistically inhibit cell proliferation in breast cancer cell lines. Targeted oncology. vol 10. issue 4. 2016-10-06. PMID:25916999. |
annexin v-pi staining and western blot assays on parp cleavage and caspase-8 and caspase-3 revealed that bibr1532 in combination with paclitaxel was more potent than either agent alone in promoting mcf-7 cell apoptosis. |
2016-10-06 |
2023-08-13 |
human |
| Zibiao Zhong, Shaojun Ye, Yan Xiong, Lianxi Wu, Meng Zhang, Xiaoli Fan, Ling Li, Zhen Fu, Huanglei Wang, Mingyun Chen, Xiaomin Yan, Wei Huang, Dicken Shiu-Chung Ko, Yanfeng Wang, Qifa Y. Decreased expression of mitochondrial aldehyde dehydrogenase-2 induces liver injury via activation of the mitogen-activated protein kinase pathway. Transplant international : official journal of the European Society for Organ Transplantation. vol 29. issue 1. 2016-10-05. PMID:26404764. |
using brain-dead rabbit model and hypoxia model, levels of aldh2 and apoptosis in tissues and cell lines were determined by western blot, flow cytometry (fcm), and transferase (tdt)-mediated biotin-16-dutp nick-end labeling (tunel) assays. |
2016-10-05 |
2023-08-13 |
rabbit |
| Xia Li, Lei Zhao, Liang Yue, Haixiao Liu, Xiangmin Yang, Xinchuan Wang, Yan Lin, Yan Q. Evidence for the protective effects of curcumin against oxyhemoglobin-induced injury in rat cortical neurons. Brain research bulletin. vol 120. 2016-09-30. PMID:26551062. |
neuronal apoptosis was assayed via tunel staining and protein levels of cleaved caspase-3, bax, and bcl-2 were measured by western blot. |
2016-09-30 |
2023-08-13 |
rat |
| Xin Huang, Shilong Huang, Fengjin Guo, Fei Xu, Peng Cheng, Yaping Ye, Yonghui Dong, Wei Xiang, Anmin Che. Dose-dependent inhibitory effects of zoledronic acid on osteoblast viability and function in vitro. Molecular medicine reports. vol 13. issue 1. 2016-09-26. PMID:26648136. |
in the present study, the effect of za on the viability, apoptosis, differentiation and maturation of mc3t3‑e1 cells, as well as its relevant molecular mechanism, were examined the results of a cell counting kit 8 assay, a flow cytometric annexin‑v/propidium iodide assay and western blot analysis demonstrated that za exhibited a significant inhibition of cell viability and induction of apoptosis at concentrations >10 µm. |
2016-09-26 |
2023-08-13 |
Not clear |
| Ryosuke Horie, Osamu Nakamura, Yoshiki Yamagami, Masaki Mori, Hideki Nishimura, Natsuko Fukuoka, Tetsuji Yamamot. Apoptosis and antitumor effects induced by the combination of an mTOR inhibitor and an autophagy inhibitor in human osteosarcoma MG63 cells. International journal of oncology. vol 48. issue 1. 2016-09-23. PMID:26530936. |
furthermore, we examined the effects of rapamycin with or without spautin-1 on the induction of apoptosis by western blot analysis and immunohistochemical staining. |
2016-09-23 |
2023-08-13 |
human |
| Farideh Asadi, Amir Hossein Jamshidi, Fariba Khodagholi, Asal Yans, Leila Azimi, Mehrdad Faizi, Leila Vali, Mohammad Abdollahi, Mohammad Hossein Ghahremani, Mohammad Sharifzade. Reversal effects of crocin on amyloid β-induced memory deficit: Modification of autophagy or apoptosis markers. Pharmacology, biochemistry, and behavior. vol 139. issue Pt A. 2016-09-22. PMID:26484504. |
furthermore, we measured certain biomarkers of cell autophagy and apoptosis using western blot analysis. |
2016-09-22 |
2023-08-13 |
Not clear |
| Xiao-Liang Chen, Jian-Ping Fu, Jun Shi, Ping Wan, Hong Cao, Zhi-Mou Tan. CXC195 induces apoptosis and endoplastic reticulum stress in human hepatocellular carcinoma cells by inhibiting the PI3K/Akt/mTOR signaling pathway. Molecular medicine reports. vol 12. issue 6. 2016-09-22. PMID:26496900. |
molecular markers of the cell cycle, apoptosis, mitochondrial function and endoplasmic reticulum (er) stress were analyzed by western blot or polymerase chain reaction analysis. |
2016-09-22 |
2023-08-13 |
human |
| Md Ali Asgar, Gulsiri Senawong, Banchob Sripa, Thanaset Senawon. Synergistic anticancer effects of cisplatin and histone deacetylase inhibitors (SAHA and TSA) on cholangiocarcinoma cell lines. International journal of oncology. vol 48. issue 1. 2016-09-22. PMID:26575528. |
cell cycle and apoptosis regulating proteins were evaluated by western blot analysis. |
2016-09-22 |
2023-08-13 |
Not clear |
| Joo Hwan Roh, Il-Gyu Ko, Sung-Eun Kim, Jae-Min Lee, Eun-Sang Ji, Ju Ho Kim, Hyun-Kyung Chang, Seung Kyu Lee, Khae Hawn Ki. Treadmill exercise ameliorates intracerebral hemorrhage-induced depression in rats. Journal of exercise rehabilitation. vol 12. issue 4. 2016-09-22. PMID:27656626. |
apoptosis in the hippocampus was detected using terminal deoxynucleotidyl transferase-mediated dutp nick end labeling assay, immunohistochemistry for caspase-3, and western blot for bcl-2 and bax. |
2016-09-22 |
2023-08-13 |
rat |
| Xiaolin Zhang, Hao Y. Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression. Iranian journal of pharmaceutical research : IJPR. vol 15. issue 2. 2016-09-19. PMID:27642320. |
western blot analysis of p53, bax, cleaved caspase-3 and myosin light chain kinase (mlck) revealed that matrine induced tumor cell apoptosis by controlling anoikis. |
2016-09-19 |
2023-08-13 |
rat |
| Yi-Hao Deng, Hong-Yun He, Li-Qiang Yang, Peng-Yue Zhan. Dynamic changes in neuronal autophagy and apoptosis in the ischemic penumbra following permanent ischemic stroke. Neural regeneration research. vol 11. issue 7. 2016-09-16. PMID:27630694. |
neuronal autophagy and apoptosis in the penumbra post-ischemia were evaluated by western blot assay and immunofluorescence staining with antibodies against lc3-ii and cleaved caspase-3, respectively. |
2016-09-16 |
2023-08-13 |
rat |
| Zhengquan Han, Shengming Zhu, Xiao Han, Zian Wang, Shiwu Wu, Rongsheng Zhen. Baicalein inhibits hepatocellular carcinoma cells through suppressing the expression of CD24. International immunopharmacology. vol 29. issue 2. 2016-09-15. PMID:26548344. |
in the present study, we evaluated anticancer effects of purified botanical extracts on hcc cells using high-throughput screening and investigated the effects of baicalein on hcc cells using proliferation and apoptosis assays, rt-pcr, and western blot. |
2016-09-15 |
2023-08-13 |
Not clear |
| Zhenzhen Wen, Shujiong Feng, Lijuan Wei, Zhimin Wang, Defei Hong, Qiang Wan. Evodiamine, a novel inhibitor of the Wnt pathway, inhibits the self-renewal of gastric cancer stem cells. International journal of molecular medicine. vol 36. issue 6. 2016-09-12. PMID:26497016. |
in order to determine the effect of evo on apoptosis of gcscs, an mts assay, flow cytometry and western blot analysis were performed. |
2016-09-12 |
2023-08-13 |
Not clear |