| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Yang, Ling Qiu, Li Zhang, Gaochao Lv, Ke Li, Huixin Yu, Minhao Xie, Jianguo Li. Platinum-zoledronate complex blocks gastric cancer cell proliferation by inducing cell cycle arrest and apoptosis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-09. PMID:26891667. |
fluorescence staining and flow cytometry (fcm) were used to monitor the cell cycle distribution and apoptosis, and western blot analysis was applied to examine the expression of several apoptosis-related proteins. |
2017-02-09 |
2023-08-13 |
human |
| Seyed Ahmad Emami, Javad Asili, Shima Hossein Nia, Rezvan Yazdian-Robati, Mehrdad Sahranavard, Zahra Tayarani-Najara. Growth Inhibition and Apoptosis Induction of Essential Oils and Extracts of Nepeta cataria L. on Human Prostatic and Breast Cancer Cell Lines. Asian Pacific journal of cancer prevention : APJCP. vol 17. issue S3. 2017-02-09. PMID:27165249. |
cell viability, histograms of pi stained fragmented dna in apoptotic cells and western blot analysis of proteins involved in the cascade of apoptosis were compared in all samples. |
2017-02-09 |
2023-08-13 |
human |
| Shuo Zhang, Lei Gao, Asmitananda Thakur, Puyu Shi, Feng Liu, Jing Feng, Ting Wang, Yiqian Liang, Johnson J Liu, Mingwei Chen, Hui Re. miRNA-204 suppresses human non-small cell lung cancer by targeting ATF2. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-08. PMID:26935060. |
rna isolation, qrt-pcr, mtt, colony formation assay, cell cycle assay, cell apoptosis assay, cell migration assay, and western blot were performed. |
2017-02-08 |
2023-08-13 |
human |
| Yingying Zhang, Mengqian Cheng, Lang Wu, Guo Zhang, Zaizhao Wan. Bisphenol A induces spermatocyte apoptosis in rare minnow Gobiocypris rarus. Aquatic toxicology (Amsterdam, Netherlands). vol 179. 2017-02-08. PMID:27561114. |
western blot results showed that the ratio of bcl2/bax, the important apoptosis regulators in intrinsic mitochondrial apoptotic pathway, was significantly decreased. |
2017-02-08 |
2023-08-13 |
Not clear |
| Zahra Goodarzi, Hoorieh Soleimanjahi, Ehsan Arefian, Esmaeil Saberfa. The effect of bovine rotavirus and its nonstructural protein 4 on ER stress-mediated apoptosis in HeLa and HT-29 cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 3. 2017-02-07. PMID:26427658. |
mtt, flow cytometry, and western blot were used to evaluate the cell viability, apoptosis, and expression level of c/ebp-homologous protein (chop) and activated caspase-4. |
2017-02-07 |
2023-08-13 |
cattle |
| Yunke Bi, Chen Shen, Chenguang Li, Yaohua Liu, Dandan Gao, Chen Shi, Fei Peng, Zhendong Liu, Boxian Zhao, Zhixing Zheng, Xiaoxiong Wang, Xu Hou, Huailei Liu, Jianing Wu, Huichao Zou, Kaikai Wang, Chen Zhong, Jiakang Zhang, Changbin Shi, Shiguang Zha. Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 3. 2017-02-07. PMID:26454746. |
western blot, flow cytometry, and immunohistochemistry were used to detect apoptosis. |
2017-02-07 |
2023-08-13 |
Not clear |
| Xiao-Lang Tan, Lei Guo, Gui-Hua Wan. Polyporus umbellatus inhibited tumor cell proliferation and promoted tumor cell apoptosis by down-regulating AKT in breast cancer. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 83. 2017-02-07. PMID:27447121. |
also, flow cytometry and western blot assays suggested that apoptosis was induced by the administration of polyporus umbellatus, which enhanced caspase-3 expressions by akt-regulated anti-apoptotic and pro-apoptotic signals. |
2017-02-07 |
2023-08-13 |
mouse |
| Ah Reum Jo, Hyo-Soon Jeong, Myo-Kyoung Kim, Hye-Young Yun, Kwang Jin Baek, Nyoun Soo Kwon, Dong-Seok Ki. Geranylgeranylacetone induces apoptosis via the intrinsic pathway in human melanoma cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 82. 2017-02-07. PMID:27470333. |
western blot analysis was adopted to detect marker proteins of apoptosis. |
2017-02-07 |
2023-08-13 |
human |
| Xi-Jun Zhang, Shen-Shan Ji. Fisetin inhibits laryngeal carcinoma through regulation of AKT/NF-κB/mTOR and ERK1/2 signaling pathways. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 83. 2017-02-07. PMID:27551764. |
in our study, flow cytometry and western blot assays suggested that apoptosis was induced by fisetin administration, promoting caspase-3 expressions by regulating pi3k/akt/nf-κb. |
2017-02-07 |
2023-08-13 |
mouse |
| Hao Zhang, Huizi Gu, Limei Li, Yuan Ren, Lijun Zhan. EZH2 mediates ATO-induced apoptosis in acute myeloid leukemia cell lines through the Wnt signaling pathway. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 5. 2017-02-06. PMID:26592252. |
the induction of spontaneous apoptosis observed in multiple ezh2-silenced leukemic cell lines was assessed by flow cytometry, and levels of wnt/β-catenin-related expression were determined by western blot analysis. |
2017-02-06 |
2023-08-13 |
Not clear |
| Wei Dai, Quangen Gao, Jianping Qiu, Jianmao Yuan, Guoliang Wu, Genhai She. Quercetin induces apoptosis and enhances 5-FU therapeutic efficacy in hepatocellular carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 5. 2017-02-06. PMID:26628295. |
the antiproliferative effects of q were measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), and the apoptosis and cell cycle dynamics were assessed by flow cytometry; the expression of apoptosis-associated proteins were evaluated by western blot and immunohistochemistry staining; the tumor growth in vivo was evaluated in a xenograft mouse model. |
2017-02-06 |
2023-08-13 |
mouse |
| Rongying Ou, Xueqi Zhang, Jianfeng Cai, Xiaohong Shao, Mingfen Lv, Wei Qiu, Xuan Xuan, Jingjing Liu, Zhiming Li, Yunsheng X. Downregulation of pyrroline-5-carboxylate reductase-2 induces the autophagy of melanoma cells via AMPK/mTOR pathway. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 5. 2017-02-06. PMID:26634742. |
the expression of pycr2 was regulated by an rnai technique, and the cell proliferation of a375 cell line was determined by methyl thiazolyl tetrazolium test; the effect of pycr2 on the apoptosis process and ampk/mtor pathway was evaluated by flow cytometry assay and western blot. |
2017-02-06 |
2023-08-13 |
Not clear |
| Yali Li, Bin Liu, Fangfang Yang, Yang Yu, Anqi Zeng, Tinghong Ye, Wenya Yin, Yongmei Xie, Zhengyan Fu, Chengjian Zha. Lobaplatin induces BGC-823 human gastric carcinoma cell apoptosis via ROS- mitochondrial apoptotic pathway and impairs cell migration and invasion. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 83. 2017-02-06. PMID:27565846. |
western blot analysis also demonstrated that the occurrence of its apoptosis was associated with activation of cleaved caspase-3 and bax, downregulation of bcl-2. |
2017-02-06 |
2023-08-13 |
human |
| Lin Lv, Hai-Guang Liu, Si-Yang Dong, Fan Yang, Qing-Xuan Wang, Gui-Long Guo, Yi-Fei Pan, Xiao-Hua Zhan. Upregulation of CD44v6 contributes to acquired chemoresistance via the modulation of autophagy in colon cancer SW480 cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 7. 2017-02-03. PMID:26747179. |
the key components in cell apoptosis, drug efflux and metabolism, mismatch repair, autophagy, epithelial-mesenchymal transition (emt), and the pi3k-akt and mapk-ras-erk1/2 pathways were assessed using flow cytometry, quantitative real-time polymerase chain reaction (pcr), and western blot assays. |
2017-02-03 |
2023-08-13 |
human |
| Andrei Alexandru Constantinescu, Malak Abbas, Mohamad Kassem, Céline Gleizes, Guillaume Kreutter, Valerie Schini-Kerth, Ioan Liviu Mitrea, Florence Toti, Laurence Kessle. Differential influence of tacrolimus and sirolimus on mitochondrial-dependent signaling for apoptosis in pancreatic cells. Molecular and cellular biochemistry. vol 418. issue 1-2. 2017-02-02. PMID:27344165. |
cleaved caspase-3, bax apoptosis indicators, and p53, p21 cell cycle regulators were detected by western blot. |
2017-02-02 |
2023-08-13 |
human |
| Qianfeng Fu, Yuling Jiang, Daxin Zhang, Xiuli Liu, Junfeng Guo, Jinlong Zha. Valosin-containing protein (VCP) promotes the growth, invasion, and metastasis of colorectal cancer through activation of STAT3 signaling. Molecular and cellular biochemistry. vol 418. issue 1-2. 2017-02-02. PMID:27344168. |
cell proliferation, invasion, apoptosis, and cell cycle arrest were subsequently examined by mtt assay, transwell chamber assay, flow cytometry, and western blot analysis, respectively. |
2017-02-02 |
2023-08-13 |
mouse |
| Gao Tianqin, Cheng Chunlei, Wang Jingjin. Synergistic Anti-glioma Effects in Vitro and in Vivo of Enediyne Antibiotic Neocarzinostatin and Paclitaxel via Enhanced Growth Delay and Apoptosis-Induction. Biological & pharmaceutical bulletin. vol 39. issue 10. 2017-02-02. PMID:27431785. |
western blot revealed that the cell signaling pathways of proliferation and apoptosis were synergistically regulated, in which akt was synergistically inactivated, p53 was up-regulated with down-regulation of bcl-2. |
2017-02-02 |
2023-08-13 |
human |
| Liping Qu, Huiqing Zhang, Yanlong Yang, Geliang Yang, Hailiang Xin, Changquan Lin. Corosolic acid analogue, a natural triterpenoid saponin, induces apoptosis on human hepatocarcinoma cells through mitochondrial pathway in vitro. Pharmaceutical biology. vol 54. issue 8. 2017-02-01. PMID:26810384. |
apoptosis changes were explored by western blot, tnf-α and caspase-3, -8, -9 assays. |
2017-02-01 |
2023-08-13 |
human |
| Qiang Liu, Xuemei Lin, Hong Li, Jia Yuan, Yuping Peng, Lei Dong, Shejiao Da. Paeoniflorin ameliorates renal function in cyclophosphamide-induced mice via AMPK suppressed inflammation and apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 84. 2017-02-01. PMID:27829543. |
moreover, western blot demonstrated that pa increased the ampk levels and inhibited nf-κb signaling pathway and apoptosis in cyp-stimulated kidney tissues. |
2017-02-01 |
2023-08-13 |
mouse |
| Xin Fan, Zhengfa Mao, Xiaoyan Ma, Lei Cui, Jianguo Qu, Lihui Lv, ShengChun Dang, Xuqing Wang, Jianxin Zhan. Secreted protein acidic and rich in cysteine enhances the chemosensitivity of pancreatic cancer cells to gemcitabine. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 2. 2017-01-31. PMID:26358255. |
then we analyzed cell viability, cell cycle, and apoptosis and the levels of apoptosis-related proteins by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, fluorescence-activated cell sorting and western blot were used, respectively. |
2017-01-31 |
2023-08-13 |
Not clear |