| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peng Wang, Qian Luo, Hui Qiao, Hui Ding, Yonggang Cao, Juan Yu, Ruxia Liu, Qianlong Zhang, Hui Zhu, Lihui Q. The Neuroprotective Effects of Carvacrol on Ethanol-Induced Hippocampal Neurons Impairment via the Antioxidative and Antiapoptotic Pathways. Oxidative medicine and cellular longevity. vol 2017. 2017-03-14. PMID:28191274. |
histopathological examinations and western blot were performed to evaluate the apoptosis of neurons. |
2017-03-14 |
2023-08-13 |
mouse |
| Xiaohui Yang, Shuai Wang, Yunchuan Mu, Yixiong Zhen. Schisandrin B inhibits cell proliferation and induces apoptosis in human cholangiocarcinoma cells. Oncology reports. vol 36. issue 4. 2017-03-13. PMID:27499090. |
mechanistically, western blot analysis indicated that sch b induced apoptosis by upregulating bax, cleaved caspase-3, cleaved caspase-9 and cleaved parp, and by downregulating cyclin d1, bcl-2 and cdk-4. |
2017-03-13 |
2023-08-13 |
mouse |
| Youwen Zhang, Deyin Tong, Daobiao Che, Bing Pei, Xiaodong Xia, Gaofeng Yuan, Xin Ji. Ascorbyl palmitate/d-α-tocopheryl polyethylene glycol 1000 succinate monoester mixed micelles for prolonged circulation and targeted delivery of compound K for antilung cancer therapy in vitro and in vivo. International journal of nanomedicine. vol 12. 2017-03-13. PMID:28144142. |
western blot analysis further confirmed that the marked antitumor effect in vivo could likely be due to apoptosis promotion and p-gp efflux inhibition. |
2017-03-13 |
2023-08-13 |
mouse |
| Shiyong Gao, Huixin Tan, Nan Zhu, Haiyu Gao, Chunyu Lv, Jian Gang, Yubin J. Oridonin induces apoptosis through the mitochondrial pathway in human gastric cancer SGC-7901 cells. International journal of oncology. vol 48. issue 6. 2017-03-10. PMID:27082253. |
apoptosis pathway was analyzed by western blot analysis of bcl-2, bax, cytochrome c and caspase-3 expression. |
2017-03-10 |
2023-08-13 |
human |
| Haohong Shi, Xingjing Lu. 7, 8, 3'-Trihydroxyflavone Promotes Neurite Outgrowth and Protects Against Bupivacaine-Induced Neurotoxicity in Mouse Dorsal Root Ganglion Neurons. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-10. PMID:27371503. |
in addition, the protective effects of thf on bupivacaine-induced neurotoxicity were investigated by apoptosis tunel assay, neurite outgrowth assay, and western blot, respectively. |
2017-03-10 |
2023-08-13 |
mouse |
| Weimin Li, Jiansheng Wu, Zhiyin Li, Zhibo Zhou, Chao Zheng, Le Lin, Binbin Tan, Min Huang, Mengdi Fa. Melatonin induces cell apoptosis in Mia PaCa-2 cells via the suppression of nuclear factor-κB and activation of ERK and JNK: A novel therapeutic implication for pancreatic cancer. Oncology reports. vol 36. issue 5. 2017-03-10. PMID:27666165. |
we also used flow cytometry to observe cell apoptosis and western blot analysis to assess the protein expression. |
2017-03-10 |
2023-08-13 |
human |
| Shaoheng Li, Yuhui Yan, Yanan Jiao, Zhong Gao, Yang Xia, Liang Kong, Yingjia Yao, Zhenyu Tao, Jie Song, Yaping Yan, Guangxian Zhang, Jingxian Yan. Neuroprotective Effect of Osthole on Neuron Synapses in an Alzheimer's Disease Cell Model via Upregulation of MicroRNA-9. Journal of molecular neuroscience : MN. vol 60. issue 1. 2017-03-09. PMID:27394443. |
in this study, the cell counting kit cck-8, apoptosis assay, immunofluorescence analysis, enzyme-linked immunosorbent assay (elisa), quantitative real-time polymerase chain reaction, and western blot assay were used. |
2017-03-09 |
2023-08-13 |
mouse |
| Xuefeng Bu, Mi Li, Yinghai Zhao, Sha Liu, Mubin Wang, Jinying Ge, Zhigao Bu, Yulan Ya. Genetically engineered Newcastle disease virus expressing human interferon-λ1 induces apoptosis in gastric adenocarcinoma cells and modulates the Th1/Th2 immune response. Oncology reports. vol 36. issue 3. 2017-03-09. PMID:27430534. |
apoptosis was significantly induced by rl-hifn-λ1 in gastric cancer cells compared with ndv virus tested by tunel assay, western blot analysis and annexin v flow cytometry. |
2017-03-09 |
2023-08-13 |
human |
| Xiaolei Li, Yu Sun, Hui Chen, Gengyao Zhu, Yuan Liang, Qiang Wang, Jingcheng Wang, Lianqi Ya. Hydroxycamptothecin induces apoptosis of fibroblasts and prevents intraarticular scar adhesion in rabbits by activating the IRE-1 signal pathway. European journal of pharmacology. vol 781. 2017-03-08. PMID:27068147. |
hcpt induced apoptosis of fibroblasts, according to cck-8 assays, hoechst staining and western blot analysis. |
2017-03-08 |
2023-08-13 |
rabbit |
| Xing Su, Xiaojiang Liu, Lanchun Ni, Wei Shi, Hui Zhu, Jinlong Shi, Jian Chen, Zhikai Gu, Yilu Gao, Qing Lan, Qingfeng Huan. GFAP expression is regulated by Pax3 in brain glioma stem cells. Oncology reports. vol 36. issue 3. 2017-03-08. PMID:27432276. |
furthermore, we studied the cell proliferation, invasion, apoptosis, differentiation and expression of pax3 and gfap in pax3 sirna-knockdown and pax3-overexpressing bgsc models by cck-8, transwell migration, flow cytometry and western blot assays. |
2017-03-08 |
2023-08-13 |
human |
| Shanshan Jiang, Qian Wang, Meiqing Feng, Jiyang Li, Zhongbin Guan, Duopeng An, Mengxue Dong, Yuzhe Peng, Kudelaidi Kuerban, Li Y. C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells. Applied microbiology and biotechnology. vol 101. issue 4. 2017-03-08. PMID:27807662. |
in this paper, the anti-hcc effect of sorafenib combined with c2-ceramide was investigated on cell vitality, apoptosis, and migration, and the underlying mechanism was examined using flow cytometry and western blot. |
2017-03-08 |
2023-08-13 |
human |
| Zixuan Yang, Zibiao Zhong, Mingxia Li, Yan Xiong, Yanfeng Wang, Guizhu Peng, Qifa Y. Hypothermic machine perfusion increases A20 expression which protects renal cells against ischemia/reperfusion injury by suppressing inflammation, apoptosis and necroptosis. International journal of molecular medicine. vol 38. issue 1. 2017-03-06. PMID:27177159. |
the expression of markers of apoptosis, necroptosis and inflammation in frozen kidney tissues were detected by western blot analysis, rt-qpcr and elisa. |
2017-03-06 |
2023-08-13 |
rabbit |
| Junjie Lu, Qian Zhang, Dongmei Tan, Wenping Luo, Hai Zhao, Jing Ma, Hao Liang, Yi Ta. GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia. International journal of molecular medicine. vol 38. issue 1. 2017-03-06. PMID:27221053. |
notably, the decrease in the invasive cell number may be due to the increased apoptosis of the htr-8/svneo cells following gabrp transfection, which was further confirmed by flow cytometry, reverse transcription-quantitative polymerase chain reaction (rt-qpcr) and western blot analysis. |
2017-03-06 |
2023-08-13 |
mouse |
| Yidong Cao, Liang Zhang, Shukai Sun, Zhenheng Yi, Xue Jiang, Dong Ji. Neuroprotective effects of syringic acid against OGD/R-induced injury in cultured hippocampal neuronal cells. International journal of molecular medicine. vol 38. issue 2. 2017-03-06. PMID:27278454. |
western blot analysis revealed that ogd/r promoted cell apoptosis with concomitant increases in bax and caspase-3 expression, and reduced bcl-2 expression, which was reversed by pre‑treatment with sa in a dose-dependent manner. |
2017-03-06 |
2023-08-13 |
Not clear |
| Qifang Liu, Yongjin Wang, Tianlun Yang, Wu We. Protective effects of miR-25 against hypoxia/reoxygenation‑induced fibrosis and apoptosis of H9c2 cells. International journal of molecular medicine. vol 38. issue 4. 2017-03-06. PMID:27513215. |
the techniques of flow cytometry, western blot analysis and rt-qpcr were used and we observed increases in the cell apoptosis rate and fibrosis as well as blocking of the cell cycle in the g1 phase. |
2017-03-06 |
2023-08-13 |
Not clear |
| Jiming Liu, Qiang Li, Zhilong Liu, Liuming Lin, Xiangqiang Zhang, Mingrong Cao, Jianwei Jian. Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways. Oncology reports. vol 35. issue 6. 2017-03-03. PMID:27004568. |
the apoptosis of sw620 cells was also detected by western blot analysis, showing caspase-3 and -9, and parp activation; the downregulation of bcl-2, mcl-1, bcl-xl; and the upregulation of bax. |
2017-03-03 |
2023-08-13 |
human |
| Xiao-Xi Kan, Qi Li, Xi Chen, Ya-Jie Wang, Yu-Jie Li, Qing Yang, Hong-Bin Xiao, Zhi-Xin Wang, Ying Chen, Xiao-Gang Weng, Wei-Yan Cai, Xiao-Xin Zh. A novel cell cycle blocker extracted from Stellera chamaejasme L. inhibits the proliferation of hepatocarcinoma cells. Oncology reports. vol 35. issue 6. 2017-03-03. PMID:27109908. |
in a mechanistic study, flow cytometry and western blot analysis were performed to evaluate the effects of esc on the induction of cell apoptosis, intervention of cell cycle distribution and its influence on key g2/m-phase regulators. |
2017-03-03 |
2023-08-13 |
mouse |
| Jinfeng Han, Zhongmin Liu, Nanya Wang, Weiyun Pa. MicroRNA-874 inhibits growth, induces apoptosis and reverses chemoresistance in colorectal cancer by targeting X-linked inhibitor of apoptosis protein. Oncology reports. vol 36. issue 1. 2017-03-03. PMID:27221209. |
rt-qpcr and western blot assays were performed to detected the levels of x-linked inhibitor of apoptosis protein (xiap) mrna and protein expression. |
2017-03-03 |
2023-08-13 |
human |
| Gang Pan, Sheng-Chun Long, Xi-Ping Xu, Jian-Hua Zhao, Zheng-Zai Li, Xu-Bin Zhang, Yong-Hua Lu, Zhi-Wei Zhan. Protective Effects of Tirofiban on Myocardial Ischemia-Reperfusion Injury in Rabbits. American journal of therapeutics. vol 23. issue 6. 2017-02-27. PMID:26035032. |
the myocardial apoptosis was identified using the terminal deoxynucleotidyl transferase-mediated dutp-biotin nick end labeling technique, and the protein expressions of b-cell lymphoma-2, bcl-2 associated x, and aquaporin-1 were measured through western blot. |
2017-02-27 |
2023-08-13 |
Not clear |
| Bin Lei, Xuming Zhou, Daojun Lv, Bo Wan, Huayan Wu, Liren Zhong, Fangpeng Shu, Xiangming Ma. Apoptotic and nonapoptotic function of caspase 7 in spermatogenesis. Asian journal of andrology. vol 19. issue 1. 2017-02-27. PMID:26643564. |
then, the mice models of spermatogenic dysfunction were obtained by busulfan (30 mg kg-1 to further evaluate the potential function and mechanism of caspase 7. qrt-pcr and western blot results showed that caspase 7 expression was gradually elevated from 5 to 14 weeks, which was not connected with apoptosis. |
2017-02-27 |
2023-08-13 |
mouse |