| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katsuhiro Takeda, Pouneh Kermani, Agustin Anastasia, Yusuke Obinata, Barbara L Hempstead, Hidemi Kurihar. BDNF protects human vascular endothelial cells from TNFα-induced apoptosis. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 91. issue 5. 2014-04-03. PMID:24032685. |
bdnf protects human vascular endothelial cells from tnfα-induced apoptosis. |
2014-04-03 |
2023-08-12 |
human |
| Guan-nan Xia, Yu Zou, You-cui Wang, Qing-jie Xia, Bing-tuan Lu, Ting-hua Wang, Jian-guo Q. Neural stem cells grafts decrease neural apoptosis associated with caspase-7 downregulation and BDNF upregulation in rats following spinal cord hemisection. Cellular and molecular neurobiology. vol 33. issue 7. 2014-04-02. PMID:23963709. |
neural stem cells grafts decrease neural apoptosis associated with caspase-7 downregulation and bdnf upregulation in rats following spinal cord hemisection. |
2014-04-02 |
2023-08-12 |
rat |
| Guan-nan Xia, Yu Zou, You-cui Wang, Qing-jie Xia, Bing-tuan Lu, Ting-hua Wang, Jian-guo Q. Neural stem cells grafts decrease neural apoptosis associated with caspase-7 downregulation and BDNF upregulation in rats following spinal cord hemisection. Cellular and molecular neurobiology. vol 33. issue 7. 2014-04-02. PMID:23963709. |
intravenous nscs injection substantially upregulated the level of bdnf mrna but not its receptor trkb in hemisected spinal cord, while caspase-7, a downstream apoptosis gene of caspase-3, has been largely down-regulated. |
2014-04-02 |
2023-08-12 |
rat |
| Jiping Liu, Liang Feng, Dongying Ma, Minghua Zhang, Junfei Gu, Shuyuan Wang, Qiang Fu, Yu Song, Zhou Lan, Rong Qu, Shiping M. Neuroprotective effect of paeonol on cognition deficits of diabetic encephalopathy in streptozotocin-induced diabetic rat. Neuroscience letters. vol 549. 2014-03-06. PMID:23791853. |
immunohistochemistry and tunel staining showed that paeonol could attenuate apoptosis of neurons and caspase 3 expression, improve two neurotrophic factors bdnf and igf expressions, and also ameliorate aβ deposition in the hippocampus and cerebral cortex. |
2014-03-06 |
2023-08-12 |
rat |
| P F Jiang, T Zhu, J D Gao, F Gao, S S Mao, W T Zhao, W Z Gu, H M Y. The effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats. Neuroscience. vol 246. 2014-02-24. PMID:23597829. |
terminal deoxynucleotidyl transferase dutp nick end labeling assay was used to determine neuronal apoptosis, immunostaining was conducted to assess neurogenesis, and western blot for extracellular signal-regulated kinase (erk), cyclic amp responsive element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2014-02-24 |
2023-08-12 |
rat |
| Nadka I Boyadjieva, Dipak K Sarka. Cyclic adenosine monophosphate and brain-derived neurotrophic factor decreased oxidative stress and apoptosis in developing hypothalamic neuronal cells: role of microglia. Alcoholism, clinical and experimental research. vol 37. issue 8. 2014-01-21. PMID:23550806. |
to study further the mechanism of etoh action on neuronal apoptosis, we determined the effects of 2 well-known pka activators, dibutyryl camp (dbcamp) and brain-derived neurotrophic factor (bdnf), on etoh-activated oxidative stress and apoptotic processes in the hypothalamic neurons in the presence and absence of microglial cells' influence. |
2014-01-21 |
2023-08-12 |
Not clear |
| Xiaomei Yang, Tracey A Martin, Wen G Jian. Biological influence of brain-derived neurotrophic factor on breast cancer cells. International journal of oncology. vol 41. issue 4. 2013-12-31. PMID:22895657. |
the impact of bdnf knockdown on growth and apoptosis was evaluated. |
2013-12-31 |
2023-08-12 |
human |
| Xiaomei Yang, Tracey A Martin, Wen G Jian. Biological influence of brain-derived neurotrophic factor on breast cancer cells. International journal of oncology. vol 41. issue 4. 2013-12-31. PMID:22895657. |
analysis of apoptosis showed that cell apoptosis was increased in cells stably transfected with ribozymes for bdnf compared with the vector control. |
2013-12-31 |
2023-08-12 |
human |
| Xiaomei Yang, Tracey A Martin, Wen G Jian. Biological influence of brain-derived neurotrophic factor on breast cancer cells. International journal of oncology. vol 41. issue 4. 2013-12-31. PMID:22895657. |
it is concluded that bdnf, a neurotrophic growth factor aberrantly expressed in cancers such as breast cancer, has a profound impact on the cellular behaviour of breast cancer cells and that bdnf is associated with a reduction of the apoptosis of breast cancer. |
2013-12-31 |
2023-08-12 |
human |
| Vishal Jain, Iswar Baitharu, Dipti Prasad, Govindasamy Ilavazhaga. Enriched environment prevents hypobaric hypoxia induced memory impairment and neurodegeneration: role of BDNF/PI3K/GSK3β pathway coupled with CREB activation. PloS one. vol 8. issue 5. 2013-12-30. PMID:23704876. |
also brain-derived neurotrophic factor (bdnf) plays a major role in ee mediated neuroprotection and it effectively prevented neurodegeneration by activating pi3k/akt pathway resulting in gsk3β inactivation which further inhibits apoptosis. |
2013-12-30 |
2023-08-12 |
rat |
| Sudheesh Pilakka-Kanthikeel, Venkata Subba Rao Atluri, Vidya Sagar, Shailendra K Saxena, Madhavan Nai. Targeted brain derived neurotropic factors (BDNF) delivery across the blood-brain barrier for neuro-protection using magnetic nano carriers: an in-vitro study. PloS one. vol 8. issue 4. 2013-12-09. PMID:23653680. |
the end point determinations of bdnf that crossed bbb were apoptosis, creb expression and dendritic spine density measurement. |
2013-12-09 |
2023-08-12 |
Not clear |
| Sudheesh Pilakka-Kanthikeel, Venkata Subba Rao Atluri, Vidya Sagar, Shailendra K Saxena, Madhavan Nai. Targeted brain derived neurotropic factors (BDNF) delivery across the blood-brain barrier for neuro-protection using magnetic nano carriers: an in-vitro study. PloS one. vol 8. issue 4. 2013-12-09. PMID:23653680. |
we found that transmigrated bdnf was effective in suppressing the morphine induced apoptosis, inducing creb expression and restoring the spine density. |
2013-12-09 |
2023-08-12 |
Not clear |
| Yun Wang, Meng Cao, Aiqin Liu, Wenyu Di, Fen Zhao, Yunjiao Tian, Jianwei Ji. Changes of inflammatory cytokines and neurotrophins emphasized their roles in hypoxic-ischemic brain damage. The International journal of neuroscience. vol 123. issue 3. 2013-10-31. PMID:23110519. |
in this article, we compared the levels of tumor necrosis factor alpha (tnf-α), intercellular adhesion molecule-1 (icam-1), interleukin 1beta (il-1β), nerve growth factor (ngf), and brain-derived neurotrophic factor (bdnf) in the progression of hibd and analyzed their correlations with apoptosis. |
2013-10-31 |
2023-08-12 |
rat |
| Yun Wang, Meng Cao, Aiqin Liu, Wenyu Di, Fen Zhao, Yunjiao Tian, Jianwei Ji. Changes of inflammatory cytokines and neurotrophins emphasized their roles in hypoxic-ischemic brain damage. The International journal of neuroscience. vol 123. issue 3. 2013-10-31. PMID:23110519. |
we found that the levels of tnf-α, icam-1, il-1β, ngf, bdnf, and neuronal apoptosis rate in neonatal rats with hibd significantly increased at 6, 24, 48, and 72 hr after hypoxia compared to the control group (p < .05) and returned back to normal by 7 days. |
2013-10-31 |
2023-08-12 |
rat |
| Yun Wang, Meng Cao, Aiqin Liu, Wenyu Di, Fen Zhao, Yunjiao Tian, Jianwei Ji. Changes of inflammatory cytokines and neurotrophins emphasized their roles in hypoxic-ischemic brain damage. The International journal of neuroscience. vol 123. issue 3. 2013-10-31. PMID:23110519. |
furthermore, neuronal apoptosis rate was positively correlated with the levels of tnf-α, icam-1, and il-1β and negatively correlated with the levels of ngf and bdnf. |
2013-10-31 |
2023-08-12 |
rat |
| Yun Wang, Meng Cao, Aiqin Liu, Wenyu Di, Fen Zhao, Yunjiao Tian, Jianwei Ji. Changes of inflammatory cytokines and neurotrophins emphasized their roles in hypoxic-ischemic brain damage. The International journal of neuroscience. vol 123. issue 3. 2013-10-31. PMID:23110519. |
inflammatory cytokines such as tnf-α, icam-1, and il-1β contribute to neuronal apoptosis induced by hibd, whereas neurotrophins ngf and bdnf antagonize it. |
2013-10-31 |
2023-08-12 |
rat |
| Lakkyong Hwang, In-Young Choi, Sung-Eun Kim, Il-Gyu Ko, Mal-Soon Shin, Chang-Ju Kim, Sang-Hoon Kim, Jun-Jang Jin, Jun-Young Chung, Jae-Woo Y. Dexmedetomidine ameliorates intracerebral hemorrhage-induced memory impairment by inhibiting apoptosis and enhancing brain-derived neurotrophic factor expression in the rat hippocampus. International journal of molecular medicine. vol 31. issue 5. 2013-10-29. PMID:23503673. |
the induction of ich deteriorated short‑term and spatial learning memory, increased apoptosis and suppressed bdnf and trkb expression in the hippocampus. |
2013-10-29 |
2023-08-12 |
rat |
| Lakkyong Hwang, In-Young Choi, Sung-Eun Kim, Il-Gyu Ko, Mal-Soon Shin, Chang-Ju Kim, Sang-Hoon Kim, Jun-Jang Jin, Jun-Young Chung, Jae-Woo Y. Dexmedetomidine ameliorates intracerebral hemorrhage-induced memory impairment by inhibiting apoptosis and enhancing brain-derived neurotrophic factor expression in the rat hippocampus. International journal of molecular medicine. vol 31. issue 5. 2013-10-29. PMID:23503673. |
treatment with dexmedetomidine ameliorated the ich‑induced impairment of short‑term and spatial learning memory by suppressing apoptosis and enhancing bdnf and trkb expression. |
2013-10-29 |
2023-08-12 |
rat |
| Sara Capoccia, Alessandra Berry, Veronica Bellisario, Davide Vacirca, Elena Ortona, Enrico Alleva, Francesca Cirull. Quality and timing of stressors differentially impact on brain plasticity and neuroendocrine-immune function in mice. Neural plasticity. vol 2013. 2013-10-29. PMID:23606988. |
we compared the effects of repeated (7 versus 21 days) restraint stress (rs) and chronic disruption of social hierarchy (ss) on neuroendocrine (corticosterone) and immune function (cytokines and splenic apoptosis) and on a marker of brain plasticity (brain-derived neurotrophic factor, bdnf ). |
2013-10-29 |
2023-08-12 |
mouse |
| Bin Qiu, Shengdi Hu, Libing Liu, Man Chen, Lai Wang, Xianwei Zeng, Shigong Zh. CART attenuates endoplasmic reticulum stress response induced by cerebral ischemia and reperfusion through upregulating BDNF synthesis and secretion. Biochemical and biophysical research communications. vol 436. issue 4. 2013-10-21. PMID:23770418. |
the results showed that cart was effective in reducing the neuronal apoptosis and expression of er stress markers (grp78, chop and cleaved caspase12), and increasing the bdnf expression in i/r injury rat cortex both in vivo and in vitro. |
2013-10-21 |
2023-08-12 |
rat |