| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hao Mei, Wei Chen, Fan Jiang, Jiang He, Sathanur Srinivasan, Erin N Smith, Nicholas Schork, Sarah Murray, Gerald S Berenso. Longitudinal replication studies of GWAS risk SNPs influencing body mass index over the course of childhood and adulthood. PloS one. vol 7. issue 2. 2012-06-18. PMID:22355368. |
these 12 snps are located at or near genes either expressed in the brain (bdnf, kctd15, tmem18, mtch2, and fto) or implicated in cell apoptosis and proliferation (faim2, map2k5, and tfap2b). |
2012-06-18 |
2023-08-12 |
human |
| C Li, C Li, X Zhu, C Wang, Zhuo Liu, W Li, Chen Lu, Xu Zho. The expression and putative role of brain-derived neurotrophic factor and its receptor in bovine sperm. Theriogenology. vol 77. issue 3. 2012-05-17. PMID:22015157. |
furthermore, bdnf promoted apoptosis of bovine sperm through trkb binding (p < 0.05). |
2012-05-17 |
2023-08-12 |
cattle |
| C Li, C Li, X Zhu, C Wang, Zhuo Liu, W Li, Chen Lu, Xu Zho. The expression and putative role of brain-derived neurotrophic factor and its receptor in bovine sperm. Theriogenology. vol 77. issue 3. 2012-05-17. PMID:22015157. |
furthermore, bdnf may affect sperm mitochondrial activity and apoptosis, as well as their viability. |
2012-05-17 |
2023-08-12 |
cattle |
| Hisatsugu Koshimizu, Shingo Suzuki, Toshiyuki Araki, Masashi Yamada, Masami Kojima, Hiroshi Hatanak. BIT/SHPS-1 promotes antiapoptotic effect of BDNF on low potassium-induced cell death of cultured cerebellar granule neurons. Cellular and molecular neurobiology. vol 31. issue 7. 2012-04-16. PMID:21553247. |
in this article, we have studied the role of bit/shps-1 in the antiapoptotic function of bdnf on low potassium (lk)-induced cell death of cultured cgns which is an in vitro model system of neuronal apoptosis during brain development. |
2012-04-16 |
2023-08-12 |
rat |
| Marieta B Heaton, Michael Paiva, Kendra Siler-Marsigli. Ethanol influences on Bax translocation, mitochondrial membrane potential, and reactive oxygen species generation are modulated by vitamin E and brain-derived neurotrophic factor. Alcoholism, clinical and experimental research. vol 35. issue 6. 2012-03-30. PMID:21332533. |
this study investigated ethanol influences on intracellular events that predispose developing neurons toward apoptosis and the capacity of the antioxidant α-tocopherol (vitamin e) and the neurotrophin brain-derived neurotrophic factor (bdnf) to modulate these effects. |
2012-03-30 |
2023-08-12 |
Not clear |
| He Xu, Hui-Ling Gao, Wei Zheng, Na Xin, Zhi-Hong Chi, Shu-Ling Bai, Zhan-You Wan. Lactational zinc deficiency-induced hippocampal neuronal apoptosis by a BDNF-independent TrkB signaling pathway. Hippocampus. vol 21. issue 5. 2012-03-26. PMID:20101602. |
the present data indicate that zinc depletion-induced hippocampal neuronal apoptosis is likely through modulation of the trkb neurotrophic signaling pathway by a bdnf-independent and src-dependent mechanism, whereas higher expression of bdnf is considered as a protective response, which cannot fully compensate for the injury caused by maternal zinc deficiency. |
2012-03-26 |
2023-08-12 |
mouse |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
hippocampal enlargement in bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal bdnf levels. |
2012-02-21 |
2023-08-12 |
mouse |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
these data show that hippocampal overgrowth in bassoon-mutant mice arises from a dysregulation of neurogenesis and apoptosis that might be associated with unbalanced bdnf levels. |
2012-02-21 |
2023-08-12 |
mouse |
| Xiao-Lu Cao, Xia-Min Hu, Jia-Qing Hu, Wen-Xia Zhen. Myocardin-related transcription factor-A promoting neuronal survival against apoptosis induced by hypoxia/ischemia. Brain research. vol 1385. 2012-02-14. PMID:21333636. |
in addition, we also found that bdnf neuroprotection on apoptosis induced by hypoxia-trophic withdrawal was not only inhibited by ly29004 and pd98059 but also partially blocked by transfection of dominant-negative mrtf-a in cortical neurons via enhancing the expression of anti-apoptotic gene-mcl-1, suggesting a downstream neuroprotective mechanism to bdnf neuroprotection on apoptosis. |
2012-02-14 |
2023-08-12 |
rat |
| Evangelos Delivopoulos, Alan F Murra. Controlled adhesion and growth of long term glial and neuronal cultures on Parylene-C. PloS one. vol 6. issue 9. 2012-02-10. PMID:21966523. |
neuronal apoptosis, often associated with the use of ara-c, is mitigated by the addition of brain derived neurotrophic factor (bdnf). |
2012-02-10 |
2023-08-12 |
rat |
| Min Dai, Xiao-Bo Xia, Si-Qi Xion. BDNF regulates GLAST and glutamine synthetase in mouse retinal Müller cells. Journal of cellular physiology. vol 227. issue 2. 2012-01-30. PMID:21448920. |
cocl(2) alone or combined with bdnf did not induce apoptosis. |
2012-01-30 |
2023-08-12 |
mouse |
| Dawei Guo, Xuezhong Hou, Hongbin Zhang, Wenyu Sun, Lei Zhu, Jian Liang, Xiaofeng Jian. More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells. Journal of experimental & clinical cancer research : CR. vol 30. 2012-01-17. PMID:21999199. |
more expressions of bdnf and trkb in multiple hepatocellular carcinoma and anti-bdnf or k252a induced apoptosis, supressed invasion of hepg2 and hcclm3 cells. |
2012-01-17 |
2023-08-12 |
human |
| Marta Kubera, Ewa Obuchowicz, Lisa Goehler, Joanna Brzeszcz, Michael Mae. In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 3. 2012-01-06. PMID:20828592. |
external stress-induced depression-like behaviors are associated with a) increased interleukin-(il)1β, tumor necrosis factor-α, il-6, nuclear factor κb, cyclooxygenase-2, expression of toll-like receptors and lipid peroxidation; b) antineurogenic effects and reduced brain-derived neurotrophic factor (bdnf) levels; and c) apoptosis with reduced levels of bcl-2 and bag1 (bcl-2 associated athanogene 1), and increased levels of caspase-3. |
2012-01-06 |
2023-08-12 |
Not clear |
| Yansong Wang, Xifan Me, Li Zhang, Gang L. Supplement moderate zinc as an effective treatment for spinal cord injury. Medical hypotheses. vol 77. issue 4. 2011-12-29. PMID:21752551. |
zinc plays an important role in regulating the expression of brain-derived neurotrophic factor (bdnf) in nervous system, which can improve the pathological state of neurons and promote regeneration of injured neurons, reduce neuronal apoptosis. |
2011-12-29 |
2023-08-12 |
Not clear |
| Ashutosh, Wei Kou, Robin Cotter, Kathleen Borgmann, Li Wu, Raisa Persidsky, Namita Sakhuja, Anuja Ghorpad. CXCL8 protects human neurons from amyloid-β-induced neurotoxicity: relevance to Alzheimer's disease. Biochemical and biophysical research communications. vol 412. issue 4. 2011-11-22. PMID:21840299. |
although cxcl8-alone did not alter neuronal survival, it did inhibit aβ-induced neuronal apoptosis and increased neuronal brain-derived neurotrophic factor (bdnf) production. |
2011-11-22 |
2023-08-12 |
human |
| Zhen-Hong Zhu, You-Shui Gao, Bing-Fang Zeng, Chang-Qing Zhan. The effect of dexamethasone and hypoxic stress on MC3T3-E1 cells. Frontiers in bioscience (Landmark edition). vol 16. 2011-10-03. PMID:21622206. |
the mitochondrial membrane potential collapsed, and the inhibitor brain- derived neurotrophic factor (bdnf) conferred effective protection against apoptosis. |
2011-10-03 |
2023-08-12 |
Not clear |
| F Truzzi, A Marconi, P Atzei, M C Panza, R Lotti, K Dallaglio, R Tiberio, E Palazzo, C Vaschieri, C Pincell. p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes. Cell death and differentiation. vol 18. issue 6. 2011-08-22. PMID:21151024. |
brain-derived neurotrophic factor (bdnf) or neurotrophin-4 (nt-4), which signals through p75ntr, induces keratinocyte apoptosis, whereas β-amyloid, a ligand for p75ntr, triggers caspase-3 activation to a greater extent in p75ntr transfected cells. |
2011-08-22 |
2023-08-12 |
human |
| F Truzzi, A Marconi, P Atzei, M C Panza, R Lotti, K Dallaglio, R Tiberio, E Palazzo, C Vaschieri, C Pincell. p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes. Cell death and differentiation. vol 18. issue 6. 2011-08-22. PMID:21151024. |
bdnf or β-amyloid fail to induce apoptosis in psoriatic ta cells, and p75ntr retroviral infection restores bdnf- or β-amyloid-induced apoptosis in psoriatic keratinocytes. |
2011-08-22 |
2023-08-12 |
human |
| Chenchen Niu, Henry K Yi. Neuroprotective signaling mechanisms of telomerase are regulated by brain-derived neurotrophic factor in rat spinal cord motor neurons. Journal of neuropathology and experimental neurology. vol 70. issue 7. 2011-08-22. PMID:21666495. |
spinal cord motor neurons with higher telomerase levels induced by bdnf became more resistant to apoptosis; survival of smns that overexpressed the catalytic protein component of telomerase with reverse transcriptase activity was also enhanced against apoptosis. |
2011-08-22 |
2023-08-12 |
rat |
| Valeriya Avdoshina, Alfredo Garzino-Demo, Alessia Bachis, Maria C G Monaco, Pauline M Maki, Rochelle E Tractenberg, Chenglong Liu, Mary A Young, Italo Mocchett. HIV-1 decreases the levels of neurotrophins in human lymphocytes. AIDS (London, England). vol 25. issue 8. 2011-07-26. PMID:21422985. |
our results support the hypothesis that reduced levels of bdnf may be a risk factor for t-cell apoptosis and for neurological complications associated with hiv-1 infection. |
2011-07-26 |
2023-08-12 |
human |