| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pengzhou Hang, Chuan Sun, Jing Guo, Jing Zhao, Zhimin D. BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats. International journal of biological sciences. vol 12. issue 8. 2017-11-07. PMID:27489501. |
our previous studies suggested that brain-derived neurotrophic factor (bdnf)/tropomyosin-related kinase b (trkb) axis inhibited cardiomyocyte apoptosis in myocardial infarction (mi). |
2017-11-07 |
2023-08-13 |
rat |
| Pengzhou Hang, Chuan Sun, Jing Guo, Jing Zhao, Zhimin D. BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats. International journal of biological sciences. vol 12. issue 8. 2017-11-07. PMID:27489501. |
the present study was performed to investigate the role of mir-195 and the interplay between bdnf and mir-195 in ischemic cardiomyocyte apoptosis. |
2017-11-07 |
2023-08-13 |
rat |
| Samira Hajheidari, Hamid Reza Sameni, Ahmad Reza Bandegi, Hossein Miladi-Gorj. Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28249787. |
effects of prolonged abstinence from meth on the hippocampal bdnf levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. |
2017-10-10 |
2023-08-13 |
rat |
| Samira Hajheidari, Hamid Reza Sameni, Ahmad Reza Bandegi, Hossein Miladi-Gorj. Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28249787. |
this study evaluated serum and hippocampal bdnf levels, neuronal numbers and apoptosis in meth-sensitized and abstinent rats. |
2017-10-10 |
2023-08-13 |
rat |
| Kei Kashiwai, Mikihito Kajiya, Shinji Matsuda, Kazuhisa Ouhara, Katsuhiro Takeda, Takashi Takata, Masae Kitagawa, Tsuyoshi Fujita, Hideki Shiba, Hidemi Kurihar. Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells. Journal of cellular biochemistry. vol 117. issue 7. 2017-09-15. PMID:26581032. |
therefore, this study aimed to investigate the effect of bdnf on cell proliferation and apoptosis in human periodontal ligament (hpl) cells and human gingival epithelial cells (oba9 cells) and to explore the molecular mechanism in vitro. |
2017-09-15 |
2023-08-13 |
human |
| Kei Kashiwai, Mikihito Kajiya, Shinji Matsuda, Kazuhisa Ouhara, Katsuhiro Takeda, Takashi Takata, Masae Kitagawa, Tsuyoshi Fujita, Hideki Shiba, Hidemi Kurihar. Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells. Journal of cellular biochemistry. vol 117. issue 7. 2017-09-15. PMID:26581032. |
bdnf facilitated not cell proliferation but cell apoptosis and jnk phosphorylation in oba9 cells. |
2017-09-15 |
2023-08-13 |
human |
| Kei Kashiwai, Mikihito Kajiya, Shinji Matsuda, Kazuhisa Ouhara, Katsuhiro Takeda, Takashi Takata, Masae Kitagawa, Tsuyoshi Fujita, Hideki Shiba, Hidemi Kurihar. Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells. Journal of cellular biochemistry. vol 117. issue 7. 2017-09-15. PMID:26581032. |
interestingly, overexpression of p75 in hpl cells upregulated cell apoptosis and jnk phosphorylation by bdnf treatment. |
2017-09-15 |
2023-08-13 |
human |
| Pengzhou Hang, Jing Zhao, Li Sun, Minghui Li, Yu Han, Zhimin Du, Yue L. Brain-derived neurotrophic factor attenuates doxorubicin-induced cardiac dysfunction through activating Akt signalling in rats. Journal of cellular and molecular medicine. vol 21. issue 4. 2017-08-07. PMID:28098423. |
meanwhile, bdnf increased cell viability, inhibited apoptosis and dna damage of dox-treated h9c2 cells. |
2017-08-07 |
2023-08-13 |
rat |
| Qun Wan, Xue Ma, Zhi-Jun Zhang, Ting Sun, Feng Xia, Gang Zhao, Yu-Mei W. Ginsenoside Reduces Cognitive Impairment During Chronic Cerebral Hypoperfusion Through Brain-Derived Neurotrophic Factor Regulated by Epigenetic Modulation. Molecular neurobiology. vol 54. issue 4. 2017-07-07. PMID:27021024. |
gsrd improved neuron survival and decreased neuron apoptosis and the level of caspase-3 under oxygen-glucose deprivation/reoxygenation (ogd/r) by upregulation of bdnf as well as in vitro. |
2017-07-07 |
2023-08-13 |
mouse |
| K Dec, A Łukomska, D Maciejewska, K Jakubczyk, I Baranowska-Bosiacka, D Chlubek, A Wąsik, I Gutowsk. The Influence of Fluorine on the Disturbances of Homeostasis in the Central Nervous System. Biological trace element research. vol 177. issue 2. 2017-06-29. PMID:27787813. |
all of those changes lead to abnormal cell differentiation and the activation of apoptosis through the changes in the expression of neural cell adhesion molecules (ncam), glial fibrillary acidic protein (gfap), brain-derived neurotrophic factor (bdnf) and map kinases. |
2017-06-29 |
2023-08-13 |
human |
| Chun-Yan Sun, Zhang-Bo Chu, Jing Huang, Lei Chen, Jian Xu, Ao-Shuang Xu, Jun-Ying Li, Yu H. siRNA-mediated inhibition of endogenous brain‑derived neurotrophic factor gene modulates the biological behavior of HeLa cells. Oncology reports. vol 37. issue 5. 2017-06-27. PMID:28405685. |
hela, a cervix cancer cell line with high expression of bdnf, was used as a living model to screen out the effective sequences of short hairpin rna of the bdnf gene, and the effects of rna interference on proliferation, apoptosis, migration and invasion of these cells were evaluated. |
2017-06-27 |
2023-08-13 |
Not clear |
| Chun-Yan Sun, Zhang-Bo Chu, Jing Huang, Lei Chen, Jian Xu, Ao-Shuang Xu, Jun-Ying Li, Yu H. siRNA-mediated inhibition of endogenous brain‑derived neurotrophic factor gene modulates the biological behavior of HeLa cells. Oncology reports. vol 37. issue 5. 2017-06-27. PMID:28405685. |
together, our data revealed that bdnf modulates the proliferation, apoptosis, migratory and invasive capabilities of hela cells. |
2017-06-27 |
2023-08-13 |
Not clear |
| Yurika Katsu-Jiménez, Frida Loría, Juan Carlos Corona, Javier Díaz-Nid. Gene Transfer of Brain-derived Neurotrophic Factor (BDNF) Prevents Neurodegeneration Triggered by FXN Deficiency. Molecular therapy : the journal of the American Society of Gene Therapy. vol 24. issue 5. 2017-06-16. PMID:26849417. |
gene transfer of bdnf to primary cultures of mouse neurons prevents the apoptosis which is triggered by the knockdown of fxn gene expression. |
2017-06-16 |
2023-08-13 |
mouse |
| Siresha Bathina, Nanduri Srinivas, Undurti N Da. Streptozotocin produces oxidative stress, inflammation and decreases BDNF concentrations to induce apoptosis of RIN5F cells and type 2 diabetes mellitus in Wistar rats. Biochemical and biophysical research communications. vol 486. issue 2. 2017-06-05. PMID:28315336. |
streptozotocin produces oxidative stress, inflammation and decreases bdnf concentrations to induce apoptosis of rin5f cells and type 2 diabetes mellitus in wistar rats. |
2017-06-05 |
2023-08-13 |
rat |
| Tapan Behl, Anita Kotwan. Downregulated Brain-Derived Neurotrophic Factor-Induced Oxidative Stress in the Pathophysiology of Diabetic Retinopathy. Canadian journal of diabetes. vol 41. issue 2. 2017-05-31. PMID:27913110. |
however, in diabetic retinopathy (a neuromicrovascular disorder involving immense neuronal degeneration), bdnf fails to provide enough neuroprotection against oxidative stress-induced retinal neuronal apoptosis. |
2017-05-31 |
2023-08-13 |
Not clear |
| Dan Xie, G David H Croaker, Jimei Li, Zan-Min Son. Reduced cell proliferation and increased apoptosis in the hippocampal formation in a rat model of Hirschsprung's disease. Brain research. vol 1642. 2017-05-22. PMID:27017960. |
these results suggest that ednrb mutation reduces cell proliferation and increases apoptosis in the hippocampal formation of the sl/sl rat, but does not alter the levels of bdnf and gdnf. |
2017-05-22 |
2023-08-13 |
rat |
| Yi Wei, Junhua Hu, Yubing Liang, Yuling Zhong, Dan He, Yi Qin, Li Li, Jing Chen, Qiang Xiao, Yubo Xi. Dexmedetomidine pretreatment attenuates propofol‑induced neurotoxicity in neuronal cultures from the rat hippocampus. Molecular medicine reports. vol 14. issue 4. 2017-04-17. PMID:27571870. |
these results showed that propofol exposure (100 µm; 3 h) reduced neuronal viability, induced cell apoptosis and decreased the expression levels of bdnf, bcl‑2 and p‑creb. |
2017-04-17 |
2023-08-13 |
rat |
| Yi Wei, Junhua Hu, Yubing Liang, Yuling Zhong, Dan He, Yi Qin, Li Li, Jing Chen, Qiang Xiao, Yubo Xi. Dexmedetomidine pretreatment attenuates propofol‑induced neurotoxicity in neuronal cultures from the rat hippocampus. Molecular medicine reports. vol 14. issue 4. 2017-04-17. PMID:27571870. |
dexmedetomidine treatment (0.001‑100 µm) of the neurons prior to propofol exposure attenuated the propofol‑induced neuronal apoptosis and increased expression levels of bdnf, bcl‑2 and p‑creb compared with the propofol only group. |
2017-04-17 |
2023-08-13 |
rat |
| Bo Jiang, Lin Gao, Dawei Lei, Jiannan Liu, Zhengbo Shao, Xinrong Zhou, Renke Li, Donglai Wu, Fei Xue, Yuanmao Zhu, Huiping Yua. Decreased expression of miR‑9 due to E50K OPTN mutation causes disruption of the expression of BDNF leading to RGC‑5 cell apoptosis. Molecular medicine reports. vol 14. issue 5. 2017-04-06. PMID:27748809. |
decreased expression of mir‑9 due to e50k optn mutation causes disruption of the expression of bdnf leading to rgc‑5 cell apoptosis. |
2017-04-06 |
2023-08-13 |
Not clear |
| A Najafi, F Amidi, M A Sedighi Gilani, A R Moawad, E Asadi, N Khanlarkhni, P Fallah, Z Rezaiian, A Sobhan. Effect of brain-derived neurotrophic factor on sperm function, oxidative stress and membrane integrity in human. Andrologia. vol 49. issue 2. 2017-03-01. PMID:27136309. |
the brain-derived neurotrophic factor (bdnf) promotes the viability of nerve cells and is known to decrease oxidative stress and apoptosis in different cells. |
2017-03-01 |
2023-08-13 |
human |