| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenbo Li, Jiyu Lou, Liping Wei, Hongying Bai, Yaohui Zhang, Yuqing H. Ethyl pyruvate protects PC12 cells from oxygen-glucose deprivation: A potential role in ischemic cerebrovascular disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 92. 2018-02-05. PMID:28538193. |
result showed that ep alleviated ogd-diminished cells viability, ogd-induced apoptosis, and ogd-reduced expressions of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf) and nestin in pc-12 cells. |
2018-02-05 |
2023-08-13 |
rat |
| Shao-Hua Su, Yue-Qing Wang, Yi-Fang Wu, Da-Peng Wang, Qi Lin, Jian Ha. Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 may protect against cognitive impairment in rats of chronic cerebral hypoperfusion via PI3K/AKT signaling. Behavioural brain research. vol 313. 2018-01-25. PMID:27424778. |
moreover, win and urb reversed the decreases in map-2 and synaptophysin expression resulting from cch, and stimulated bdnf and cb1 expression as well as creb, foxo3a, gsk-3β, and bad phosphorylation, confirming that win and urb mediate neuroprotection by preventing neuronal apoptosis and improving cognition via pi3k/akt signaling. |
2018-01-25 |
2023-08-13 |
rat |
| A B Ozer, S Ceribasi, A O Ceribasi, I Demirel, M K Bayar, B Ustundag, A Ileri, O L Erha. Effects of sevoflurane on apoptosis, BDNF and cognitive functions in neonatal rats. Bratislavske lekarske listy. vol 118. issue 2. 2017-12-08. PMID:28814087. |
effects of sevoflurane on apoptosis, bdnf and cognitive functions in neonatal rats. |
2017-12-08 |
2023-08-13 |
rat |
| Shahdat Hossain, Sujan Bhowmick, Sabrin Jahan, Liza Rozario, Marzan Sarkar, Saiful Islam, Mafroz Ahmed Basunia, Azizur Rahman, Bazlul Karim Choudhury, Hussain Shahjala. Maternal lead exposure decreases the levels of brain development and cognition-related proteins with concomitant upsurges of oxidative stress, inflammatory response and apoptosis in the offspring rats. Neurotoxicology. vol 56. 2017-11-20. PMID:27492863. |
we studied whether gestational/lactational pb-exposure affects oxidative stress, proinflammatory response, apoptosis and levels of brain development/cognition-related proteins, including presynaptic synaptosome-associated protein-25 (snap-25), postsynaptic density protein-95 (psd-95), brain-derived neurotropic factor (bdnf), tyrosine receptor-kinase protein b (trkb) and vesicular acetylcholine transporter (vacht) in the offspring. |
2017-11-20 |
2023-08-13 |
rat |
| Tae-Woon Kim, Yun-Hee Sun. Regular exercise promotes memory function and enhances hippocampal neuroplasticity in experimental autoimmune encephalomyelitis mice. Neuroscience. vol 346. 2017-11-09. PMID:28108255. |
we found decreased memory ability in eae mice, accompanied by impaired myelination, increased apoptosis and cell proliferation, and decreased bdnf in the hippocampus. |
2017-11-09 |
2023-08-13 |
mouse |
| Tae-Woon Kim, Yun-Hee Sun. Regular exercise promotes memory function and enhances hippocampal neuroplasticity in experimental autoimmune encephalomyelitis mice. Neuroscience. vol 346. 2017-11-09. PMID:28108255. |
the memory decline and changes in demyelination, apoptosis, bdnf, and cell proliferation were partially reversed in eae+ex mice. |
2017-11-09 |
2023-08-13 |
mouse |
| Pengzhou Hang, Chuan Sun, Jing Guo, Jing Zhao, Zhimin D. BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats. International journal of biological sciences. vol 12. issue 8. 2017-11-07. PMID:27489501. |
our previous studies suggested that brain-derived neurotrophic factor (bdnf)/tropomyosin-related kinase b (trkb) axis inhibited cardiomyocyte apoptosis in myocardial infarction (mi). |
2017-11-07 |
2023-08-13 |
rat |
| Pengzhou Hang, Chuan Sun, Jing Guo, Jing Zhao, Zhimin D. BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats. International journal of biological sciences. vol 12. issue 8. 2017-11-07. PMID:27489501. |
the present study was performed to investigate the role of mir-195 and the interplay between bdnf and mir-195 in ischemic cardiomyocyte apoptosis. |
2017-11-07 |
2023-08-13 |
rat |
| Samira Hajheidari, Hamid Reza Sameni, Ahmad Reza Bandegi, Hossein Miladi-Gorj. Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28249787. |
effects of prolonged abstinence from meth on the hippocampal bdnf levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. |
2017-10-10 |
2023-08-13 |
rat |
| Samira Hajheidari, Hamid Reza Sameni, Ahmad Reza Bandegi, Hossein Miladi-Gorj. Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28249787. |
this study evaluated serum and hippocampal bdnf levels, neuronal numbers and apoptosis in meth-sensitized and abstinent rats. |
2017-10-10 |
2023-08-13 |
rat |
| Kei Kashiwai, Mikihito Kajiya, Shinji Matsuda, Kazuhisa Ouhara, Katsuhiro Takeda, Takashi Takata, Masae Kitagawa, Tsuyoshi Fujita, Hideki Shiba, Hidemi Kurihar. Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells. Journal of cellular biochemistry. vol 117. issue 7. 2017-09-15. PMID:26581032. |
therefore, this study aimed to investigate the effect of bdnf on cell proliferation and apoptosis in human periodontal ligament (hpl) cells and human gingival epithelial cells (oba9 cells) and to explore the molecular mechanism in vitro. |
2017-09-15 |
2023-08-13 |
human |
| Kei Kashiwai, Mikihito Kajiya, Shinji Matsuda, Kazuhisa Ouhara, Katsuhiro Takeda, Takashi Takata, Masae Kitagawa, Tsuyoshi Fujita, Hideki Shiba, Hidemi Kurihar. Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells. Journal of cellular biochemistry. vol 117. issue 7. 2017-09-15. PMID:26581032. |
bdnf facilitated not cell proliferation but cell apoptosis and jnk phosphorylation in oba9 cells. |
2017-09-15 |
2023-08-13 |
human |
| Kei Kashiwai, Mikihito Kajiya, Shinji Matsuda, Kazuhisa Ouhara, Katsuhiro Takeda, Takashi Takata, Masae Kitagawa, Tsuyoshi Fujita, Hideki Shiba, Hidemi Kurihar. Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells. Journal of cellular biochemistry. vol 117. issue 7. 2017-09-15. PMID:26581032. |
interestingly, overexpression of p75 in hpl cells upregulated cell apoptosis and jnk phosphorylation by bdnf treatment. |
2017-09-15 |
2023-08-13 |
human |
| Pengzhou Hang, Jing Zhao, Li Sun, Minghui Li, Yu Han, Zhimin Du, Yue L. Brain-derived neurotrophic factor attenuates doxorubicin-induced cardiac dysfunction through activating Akt signalling in rats. Journal of cellular and molecular medicine. vol 21. issue 4. 2017-08-07. PMID:28098423. |
meanwhile, bdnf increased cell viability, inhibited apoptosis and dna damage of dox-treated h9c2 cells. |
2017-08-07 |
2023-08-13 |
rat |
| Qun Wan, Xue Ma, Zhi-Jun Zhang, Ting Sun, Feng Xia, Gang Zhao, Yu-Mei W. Ginsenoside Reduces Cognitive Impairment During Chronic Cerebral Hypoperfusion Through Brain-Derived Neurotrophic Factor Regulated by Epigenetic Modulation. Molecular neurobiology. vol 54. issue 4. 2017-07-07. PMID:27021024. |
gsrd improved neuron survival and decreased neuron apoptosis and the level of caspase-3 under oxygen-glucose deprivation/reoxygenation (ogd/r) by upregulation of bdnf as well as in vitro. |
2017-07-07 |
2023-08-13 |
mouse |
| K Dec, A Łukomska, D Maciejewska, K Jakubczyk, I Baranowska-Bosiacka, D Chlubek, A Wąsik, I Gutowsk. The Influence of Fluorine on the Disturbances of Homeostasis in the Central Nervous System. Biological trace element research. vol 177. issue 2. 2017-06-29. PMID:27787813. |
all of those changes lead to abnormal cell differentiation and the activation of apoptosis through the changes in the expression of neural cell adhesion molecules (ncam), glial fibrillary acidic protein (gfap), brain-derived neurotrophic factor (bdnf) and map kinases. |
2017-06-29 |
2023-08-13 |
human |
| Chun-Yan Sun, Zhang-Bo Chu, Jing Huang, Lei Chen, Jian Xu, Ao-Shuang Xu, Jun-Ying Li, Yu H. siRNA-mediated inhibition of endogenous brain‑derived neurotrophic factor gene modulates the biological behavior of HeLa cells. Oncology reports. vol 37. issue 5. 2017-06-27. PMID:28405685. |
hela, a cervix cancer cell line with high expression of bdnf, was used as a living model to screen out the effective sequences of short hairpin rna of the bdnf gene, and the effects of rna interference on proliferation, apoptosis, migration and invasion of these cells were evaluated. |
2017-06-27 |
2023-08-13 |
Not clear |
| Chun-Yan Sun, Zhang-Bo Chu, Jing Huang, Lei Chen, Jian Xu, Ao-Shuang Xu, Jun-Ying Li, Yu H. siRNA-mediated inhibition of endogenous brain‑derived neurotrophic factor gene modulates the biological behavior of HeLa cells. Oncology reports. vol 37. issue 5. 2017-06-27. PMID:28405685. |
together, our data revealed that bdnf modulates the proliferation, apoptosis, migratory and invasive capabilities of hela cells. |
2017-06-27 |
2023-08-13 |
Not clear |
| Yurika Katsu-Jiménez, Frida Loría, Juan Carlos Corona, Javier Díaz-Nid. Gene Transfer of Brain-derived Neurotrophic Factor (BDNF) Prevents Neurodegeneration Triggered by FXN Deficiency. Molecular therapy : the journal of the American Society of Gene Therapy. vol 24. issue 5. 2017-06-16. PMID:26849417. |
gene transfer of bdnf to primary cultures of mouse neurons prevents the apoptosis which is triggered by the knockdown of fxn gene expression. |
2017-06-16 |
2023-08-13 |
mouse |
| Siresha Bathina, Nanduri Srinivas, Undurti N Da. Streptozotocin produces oxidative stress, inflammation and decreases BDNF concentrations to induce apoptosis of RIN5F cells and type 2 diabetes mellitus in Wistar rats. Biochemical and biophysical research communications. vol 486. issue 2. 2017-06-05. PMID:28315336. |
streptozotocin produces oxidative stress, inflammation and decreases bdnf concentrations to induce apoptosis of rin5f cells and type 2 diabetes mellitus in wistar rats. |
2017-06-05 |
2023-08-13 |
rat |