| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinwang Ying, Wenzhan Tu, Sisi Li, Qiaoyun Wu, Xiaolong Chen, Ye Zhou, Jie Hu, Guanhu Yang, Songhe Jian. Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats. Life sciences. vol 229. 2019-07-05. PMID:31108095. |
we found hbot suppressed dendritic/synaptic degeneration and alleviated apoptosis, consistent with the increase of bdnf and trkb expression and improved neurological recovery. |
2019-07-05 |
2023-08-13 |
rat |
| Julieta Saba, Juan Turati, Delia Ramírez, Lila Carniglia, Daniela Durand, Mercedes Lasaga, Carla Carus. Astrocyte truncated tropomyosin receptor kinase B mediates brain-derived neurotrophic factor anti-apoptotic effect leading to neuroprotection. Journal of neurochemistry. vol 146. issue 6. 2019-06-26. PMID:29851427. |
we found that bdnf increased astrocyte viability, preventing apoptosis induced by serum deprivation by decreasing active caspase 3 and p53 expression. |
2019-06-26 |
2023-08-13 |
Not clear |
| L Gao, P Yan, F F Guo, H J Liu, Z F Zha. MiR-1-3p inhibits cell proliferation and invasion by regulating BDNF-TrkB signaling pathway in bladder cancer. Neoplasma. vol 65. issue 1. 2019-06-25. PMID:29322793. |
transfections of mir-1-3p mimics and bdnf sirnas can suppress bc cell proliferation, invasion and induce cell apoptosis. |
2019-06-25 |
2023-08-13 |
Not clear |
| R Ranjithkumar, Qasim Alhadidi, Zahoor A Shah, Muthiah Ramanatha. Tribulusterine Containing Tribulus terrestris Extract Exhibited Neuroprotection Through Attenuating Stress Kinases Mediated Inflammatory Mechanism: In Vitro and In Vivo Studies. Neurochemical research. vol 44. issue 5. 2019-06-11. PMID:30863969. |
the present study has been aimed to explore the different secondary messengers of the inflammatory pathway nf-κb, kinases (jnk, p38mapk, gsk3β/βcatenin), apoptosis pathway (caspase-3 and aif), and neuronal survival pathway (bdnf) in order to understand the neuroprotective mechanism of aqueous extract of tribulus terrestris (aqtt). |
2019-06-11 |
2023-08-13 |
Not clear |
| Ola A Salama, Maha M Attia, Mohamed A S Abdelraze. Modulatory effects of swimming exercise against malathion induced neurotoxicity in male and female rats. Pesticide biochemistry and physiology. vol 157. 2019-06-10. PMID:31153460. |
therefore, this study was planned to assess the modulatory effects of regular exercise performance on brain bdnf level, cholinergic activity, oxidative stress and apoptosis in male and female rats subjected to neurotoxicity induced by malathion administration. |
2019-06-10 |
2023-08-13 |
rat |
| Yan Luo, Daogong Zhang, Yueling Chen, Zhongsheng Cao, Zhaomin Fa. Dexamethasone protects against arsanilic acid‑induced rat vestibular dysfunction through the BDNF and JNK 1/2 signaling pathways. Molecular medicine reports. vol 19. issue 3. 2019-05-31. PMID:30628712. |
in brain tissues, histopathological alterations, cell apoptosis, expression levels and patterns of bdnf signaling pathway‑associated bdnf, tyrosine receptor kinase b (trkb) and k+/cl‑ cotransporter isoform 2 (kcc2), and the expression of apoptosis‑related cleaved‑caspase 3 and the jnk signaling pathway were detected. |
2019-05-31 |
2023-08-13 |
rat |
| Yan Luo, Daogong Zhang, Yueling Chen, Zhongsheng Cao, Zhaomin Fa. Dexamethasone protects against arsanilic acid‑induced rat vestibular dysfunction through the BDNF and JNK 1/2 signaling pathways. Molecular medicine reports. vol 19. issue 3. 2019-05-31. PMID:30628712. |
it was identified that dxms relieved aa‑induced vestibular dysfunction, leading to improvement in rat behavior scores to normal levels, minimizing brain damage at the histopatholojnnkngical level, reducing cell apoptosis, enhancing the expression of bdnf, trkb and kcc2, and downregulating cleaved‑caspase 3 and phosphorylated‑jnk1/2 in brain tissues. |
2019-05-31 |
2023-08-13 |
rat |
| Siamak Shahidi, Alireza Komaki, Reihaneh Sadeghian, Sara Soleimani As. Different doses of methamphetamine alter long-term potentiation, level of BDNF and neuronal apoptosis in the hippocampus of reinstated rats. The journal of physiological sciences : JPS. vol 69. issue 2. 2019-05-28. PMID:30680641. |
different doses of methamphetamine alter long-term potentiation, level of bdnf and neuronal apoptosis in the hippocampus of reinstated rats. |
2019-05-28 |
2023-08-13 |
rat |
| Siamak Shahidi, Alireza Komaki, Reihaneh Sadeghian, Sara Soleimani As. Different doses of methamphetamine alter long-term potentiation, level of BDNF and neuronal apoptosis in the hippocampus of reinstated rats. The journal of physiological sciences : JPS. vol 69. issue 2. 2019-05-28. PMID:30680641. |
therefore, we investigated the effects of different doses of meth on long-term potentiation (ltp), bdnf expression and neuronal apoptosis in the hippocampus of reinstated rats. |
2019-05-28 |
2023-08-13 |
rat |
| Siamak Shahidi, Alireza Komaki, Reihaneh Sadeghian, Sara Soleimani As. Different doses of methamphetamine alter long-term potentiation, level of BDNF and neuronal apoptosis in the hippocampus of reinstated rats. The journal of physiological sciences : JPS. vol 69. issue 2. 2019-05-28. PMID:30680641. |
following implementation of the reinstatement model, electrophysiology, western blotting and tunel assay were performed to assess behavior, ltp components, bdnf expression, and neuronal apoptosis, respectively. |
2019-05-28 |
2023-08-13 |
rat |
| Siamak Shahidi, Alireza Komaki, Reihaneh Sadeghian, Sara Soleimani As. Different doses of methamphetamine alter long-term potentiation, level of BDNF and neuronal apoptosis in the hippocampus of reinstated rats. The journal of physiological sciences : JPS. vol 69. issue 2. 2019-05-28. PMID:30680641. |
these results suggest that alterations in synaptic plasticity, expression of bdnf and neuronal apoptosis in the hippocampus has a vital role in the context-induced reinstatement of meth seeking. |
2019-05-28 |
2023-08-13 |
rat |
| Ganlin Zhu, Yiming Liu, Ye Zhi, Yang Jin, Jinlong Li, Weiwei Shi, Yuting Liu, Yu Han, Shali Yu, Junkang Jiang, Xinyuan Zha. PKA- and Ca Toxicology letters. vol 309. 2019-05-06. PMID:30951808. |
furthermore, downregulation of creb with shrna plasmid transfection significantly worsened the pc12 cell apoptosis by decreasing mrna and protein expression of brain-derived neurotrophic factor (bdnf). |
2019-05-06 |
2023-08-13 |
mouse |
| Yasin Asadi, Fazel Gorjipour, Sedigheh Behrouzifar, Abedin Vakil. Irisin Peptide Protects Brain Against Ischemic Injury Through Reducing Apoptosis and Enhancing BDNF in a Rodent Model of Stroke. Neurochemical research. vol 43. issue 8. 2019-04-01. PMID:29882126. |
irisin peptide protects brain against ischemic injury through reducing apoptosis and enhancing bdnf in a rodent model of stroke. |
2019-04-01 |
2023-08-13 |
mouse |
| Yasin Asadi, Fazel Gorjipour, Sedigheh Behrouzifar, Abedin Vakil. Irisin Peptide Protects Brain Against Ischemic Injury Through Reducing Apoptosis and Enhancing BDNF in a Rodent Model of Stroke. Neurochemical research. vol 43. issue 8. 2019-04-01. PMID:29882126. |
the present study aimed to assess the effects of recombinant irisin on the infarct size, neurological outcomes, blood-brain barrier (bbb) permeability, apoptosis and brain-derived neurotrophic factor (bdnf) expression in a mouse model of stroke. |
2019-04-01 |
2023-08-13 |
mouse |
| Yasin Asadi, Fazel Gorjipour, Sedigheh Behrouzifar, Abedin Vakil. Irisin Peptide Protects Brain Against Ischemic Injury Through Reducing Apoptosis and Enhancing BDNF in a Rodent Model of Stroke. Neurochemical research. vol 43. issue 8. 2019-04-01. PMID:29882126. |
the present study indicated that irisin attenuates brain damage via reducing apoptosis and increasing bdnf protein of brain cortex in the experimental model of stroke in mice. |
2019-04-01 |
2023-08-13 |
mouse |
| Selim Çomakli, Mine Köktürk, Ahmet Topal, Mustafa Özkaraca, Saltuk Buğrahan Ceyhu. Immunofluorescence/fluorescence assessment of brain-derived neurotrophic factor, c-Fos activation, and apoptosis in the brain of zebrafish (Danio rerio) larvae exposed to glufosinate. Neurotoxicology. vol 69. 2019-03-15. PMID:30222997. |
in this study, we investigated the potential neuro-toxicological mechanism of the glufosinate in the brain of zebrafish larvae in terms of bdnf and c-fos proteins by evaluating apoptosis, immunofluorescence bdnf, and c-fos activation. |
2019-03-15 |
2023-08-13 |
zebrafish |
| Selim Çomakli, Mine Köktürk, Ahmet Topal, Mustafa Özkaraca, Saltuk Buğrahan Ceyhu. Immunofluorescence/fluorescence assessment of brain-derived neurotrophic factor, c-Fos activation, and apoptosis in the brain of zebrafish (Danio rerio) larvae exposed to glufosinate. Neurotoxicology. vol 69. 2019-03-15. PMID:30222997. |
the results have indicated that exposure to glufosinate caused to embryonic death, hatching delay, induction of apoptosis, increasing of c-fos activity and the level of bdnf in a dose-dependent manner. |
2019-03-15 |
2023-08-13 |
zebrafish |
| Selim Çomakli, Mine Köktürk, Ahmet Topal, Mustafa Özkaraca, Saltuk Buğrahan Ceyhu. Immunofluorescence/fluorescence assessment of brain-derived neurotrophic factor, c-Fos activation, and apoptosis in the brain of zebrafish (Danio rerio) larvae exposed to glufosinate. Neurotoxicology. vol 69. 2019-03-15. PMID:30222997. |
as a conclusion, we suggested that c-fos might play a role in the regulation of bdnf which responses to prevent the cell from apoptosis even in case of unsuccessful in zebrafish larvae exposed to glufosinate. |
2019-03-15 |
2023-08-13 |
zebrafish |
| Cassiano R A F Diniz, Plinio C Casarotto, Leonardo Resstel, Sâmia R L Joc. Beyond good and evil: A putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment. Neuroscience and biobehavioral reviews. vol 90. 2019-03-07. PMID:29626490. |
in contrast, both precursor probdnf and bdnf propeptide (another metabolic product from probdnf cleavage) have a high affinity to p75 receptor (p75r) and usually convey apoptosis and neuronal shrinkage. |
2019-03-07 |
2023-08-13 |
Not clear |
| Yuan Zhong, Yitong Zhu, Ting He, Wei Li, Qinjie Li, Ya Mia. Brain-derived neurotrophic factor inhibits hyperglycemia-induced apoptosis and downregulation of synaptic plasticity-related proteins in hippocampal neurons via the PI3K/Akt pathway. International journal of molecular medicine. vol 43. issue 1. 2019-03-05. PMID:30365051. |
it is not known whether brain‑derived neurotrophic factor (bdnf) protects hippocampal neurons from high glucose‑induced apoptosis and/or synaptic plasticity dysfunction. |
2019-03-05 |
2023-08-13 |
rat |