| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tingting Zhou, Suli He, Xin Ye, Zhaolan Wei, Jian Wan, Hongmao Zhang, Shumao Din. Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF. The Science of the total environment. 2022-08-30. PMID:36041608. |
rt-pcr results revealed that the expression levels of p53, caspase3, and bax genes related to apoptosis were up-regulated. |
2022-08-30 |
2023-08-14 |
mouse |
| Ying Li, Wenjie Cai, Zichun Ai, Chenyu Xue, Rujing Cao, Na Don. Protective effects of sinomenine hydrochloride on lead-induced oxidative stress, inflammation, and apoptosis in mouse liver. Environmental science and pollution research international. 2022-08-29. PMID:36038687. |
the messenger rna (mrna) expression levels of the cytokines il-1β and tnf-α and the apoptosis factors bax, bcl-2, and caspase3 in the liver were detected by quantitative real-time pcr. |
2022-08-29 |
2023-08-14 |
mouse |
| Ying Li, Wenjie Cai, Zichun Ai, Chenyu Xue, Rujing Cao, Na Don. Protective effects of sinomenine hydrochloride on lead-induced oxidative stress, inflammation, and apoptosis in mouse liver. Environmental science and pollution research international. 2022-08-29. PMID:36038687. |
immunohistochemical determination of the expression of the apoptosis factors bax, bcl-2, and caspase3 was performed. |
2022-08-29 |
2023-08-14 |
mouse |
| Ying Li, Wenjie Cai, Zichun Ai, Chenyu Xue, Rujing Cao, Na Don. Protective effects of sinomenine hydrochloride on lead-induced oxidative stress, inflammation, and apoptosis in mouse liver. Environmental science and pollution research international. 2022-08-29. PMID:36038687. |
quantitative real-time pcr, elisa, and immunohistochemical analysis showed that sh inhibited apoptosis, as indicated by the regulation of the mrna expression of bax and bcl-2 and the reduced expression of caspase3 and pro-inflammatory factors (il-1β and tnf-α) in the livers of pb-treated mice. |
2022-08-29 |
2023-08-14 |
mouse |
| Jian Lu, Weiguo Wang, Cheng Zhang, Wenping Xu, Weidong Chen, Liming Tao, Zhong Li, Jiagao Cheng, Yang Zhan. Characterization of glyphosate-induced cardiovascular toxicity and apoptosis in zebrafish. The Science of the total environment. 2022-08-28. PMID:36030873. |
mechanistically, apoptosis clustered in the heart and vascular regions and levels of atp and apoptosis-related genes including caspase-3, caspase-9, bax, and bcl-2 were altered. |
2022-08-28 |
2023-08-14 |
human |
| Yanhong Yong, Junyu Li, Tianyue Yu, Biao Fang, Xiaoxi Liu, Zhichao Yu, Xinbin Ma, Ravi Gooneratne, A M Abd El-Aty, Xianghong J. Overexpression of heat shock protein 70 induces apoptosis of intestinal epithelial cells in heat-stressed pigs: A proteomics approach. Journal of thermal biology. vol 108. 2022-08-28. PMID:36031210. |
furtherly, the apoptosis rate and expression levels of apoptosis-related proteins in hsp70 transfected ipec-j2 cells were detected, we found that the expression of caspase-3, parp, and bax were increased, but bcl-2 were decreased in transfected cells. |
2022-08-28 |
2023-08-14 |
Not clear |
| Yanhong Yong, Junyu Li, Tianyue Yu, Biao Fang, Xiaoxi Liu, Zhichao Yu, Xinbin Ma, Ravi Gooneratne, A M Abd El-Aty, Xianghong J. Overexpression of heat shock protein 70 induces apoptosis of intestinal epithelial cells in heat-stressed pigs: A proteomics approach. Journal of thermal biology. vol 108. 2022-08-28. PMID:36031210. |
the results of in vitrol study showed that hs-induced cellular apoptosis and increases of caspase-3, parp, and bax, but decreased of bcl-2 in ipec-j2 cells. |
2022-08-28 |
2023-08-14 |
Not clear |
| Xin-Mei Gao, Wen-Han Dong, Chun-Lei Xia, Zhuo-Yi Ma, Ying Wang, Setrerrahmane Sarra, Han-Mei Xu, Wei-Yan Q. Centranthera grandiflore alleviates alcohol-induced oxidative stress and cell apoptosis. Chinese journal of natural medicines. vol 20. issue 8. 2022-08-28. PMID:36031229. |
cgw also affected cell apoptosis by inhibiting the activity of bax, cleaved-caspase 3 and cleaved-caspase 9, and increasing the activity of bcl-2. |
2022-08-28 |
2023-08-14 |
mouse |
| Natasa Bajalovic, Yu Zuan Or, Amanda R E Woo, Shi Hao Lee, Valerie C L Li. High Levels of Progesterone Receptor B in MCF-7 Cells Enable Radical Anti-Tumoral and Anti-Estrogenic Effect of Progestin. Biomedicines. vol 10. issue 8. 2022-08-26. PMID:36009407. |
although r5020 caused a significant increase of cd24+cd44+ cell population, r5020-treated mcf-7prb cells were unable to form tumorspheres and underwent massive apoptosis, which is paradoxically associated with marked downregulations of the pro-apoptotic proteins bid, bax, parp, and caspases 7 and 8, as well as diminution of anti-apoptotic protein bcl-2. |
2022-08-26 |
2023-08-14 |
Not clear |
| Abdulmohsin J Alamoudi, Sami A Alessi, Waleed Y Rizg, Abdulmajeed M Jali, Awaji Y Safhi, Fahad Y Sabei, Sameer Alshehri, Khaled M Hosny, Ashraf B Abdel-Nai. Cordycepin Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats via Modulation of AMPK and AKT Activation. Pharmaceutics. vol 14. issue 8. 2022-08-26. PMID:36015278. |
it also enhanced apoptosis as demonstrated by its ability to enhance and inhibit mrna expression of bax and bcl2, respectively. |
2022-08-26 |
2023-08-14 |
rat |
| Yuting Wu, Jiwen Liu, Shuhui Liu, Wentao Fan, Chenchen Ding, Zhangshan Gao, Zhihui Tang, Yan Luo, Xizhi Shi, Lei Tan, Suquan Son. Bromoacetic acid causes oxidative stress and uric acid metabolism dysfunction via disturbing mitochondrial function and Nrf2 pathway in chicken kidney. Environmental toxicology. 2022-08-26. PMID:36017758. |
baa led to disorder in renal function (cre, bun, ua) and increased apoptosis (bax, bcl-2, caspase3). |
2022-08-26 |
2023-08-14 |
chicken |
| Jirakhamon Sengking, Chio Oka, Nuttapong Yawoot, Jiraporn Tocharus, Waraluck Chaichompoo, Apichart Suksamrarn, Chainarong Tocharu. Protective Effect of Neferine in Permanent Cerebral Ischemic Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms. Neurotoxicity research. 2022-08-26. PMID:36018507. |
neferine treatment also significantly decreased apoptosis, with a decrease in bax and cleaved caspase-3 and an increase in bcl-2. |
2022-08-26 |
2023-08-14 |
rat |
| Lulu Hou, Dongxu Wang, Kai Yin, Yue Zhang, Hongmin Lu, Tiantian Guo, Junbo Li, Hongjing Zhao, Mingwei Xin. Polystyrene microplastics induce apoptosis in chicken testis via crosstalk between NF-κB and Nrf2 pathways. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022-08-25. PMID:36007826. |
under redox system imbalance and inflammatory stress, exposure to ps-mps led to decreased expression of bcl-2 and increased bax, cytc, caspase-8, and caspase-3, etc., activating apoptosis, and ultimately causing testicular damage. |
2022-08-25 |
2023-08-14 |
chicken |
| Vaishnavi K Nimbalkar, Jeet Gangar, Saptarsi Shai, Pallavi Rane, Subham Kumar Mohanta, Sadhana Kannan, Arvind Ingle, Neha Mittal, Swapnil Rane, Manoj B Mahimka. Prevention of carcinogen-induced oral cancers by polymeric black tea polyphenols via modulation of EGFR-Akt-mTOR pathway. Scientific reports. vol 12. issue 1. 2022-08-25. PMID:36008552. |
there was also a pbps mediated dose-dependent increase in apoptosis (bax). |
2022-08-25 |
2023-08-14 |
Not clear |
| Ling Liu, Bingyan Liu, Bowen Zhang, Yiyuan Ye, Wei Jian. Polystyrene micro(nano)plastics damage the organelles of RBL-2H3 cells and promote MOAP-1 to induce apoptosis. Journal of hazardous materials. vol 438. 2022-08-24. PMID:35999725. |
anti-apoptotic genes (bcl-2) were down regulated, and pro-apoptotic genes (bax) and a key gene (caspase-3) in apoptosis were upregulated. |
2022-08-24 |
2023-08-14 |
rat |
| Ling Liu, Bingyan Liu, Bowen Zhang, Yiyuan Ye, Wei Jian. Polystyrene micro(nano)plastics damage the organelles of RBL-2H3 cells and promote MOAP-1 to induce apoptosis. Journal of hazardous materials. vol 438. 2022-08-24. PMID:35999725. |
hence, ps-particles may promote the binding of moap-1 and bax, which ultimately activates caspase-3 and causes apoptosis through the mitochondrial pathway. |
2022-08-24 |
2023-08-14 |
rat |
| Shuang Liu, An-Qi Ju, Ao-Yi Duan, Cheng-Lin Zhan, Le-Peng Gao, Xin Ma, Shu-Bao Yan. Presence of Ginsenoside Re during in vitro maturation protects porcine oocytes from heat stress. Reproduction in domestic animals = Zuchthygiene. 2022-08-24. PMID:36001037. |
moreover, hs increased the ros formation and percentage of apoptosis, the gene expression of hsp90, casp3 and cytoc of porcine oocytes, but gre could weaken the effect on cyto c and bax expression induced by hs. |
2022-08-24 |
2023-08-14 |
Not clear |
| b' Kochar Khasro Saleh, Sevda Kirbag, Semih Dalk\\xc4\\xb1l\\xc4\\xb1\\xc3\\xa. Inhibitory Effects of Terfezia (Ascomycota) Desert Truffles on PANC-1 Cell Growth via Upregulation of Proapoptotic Genes TP53, CDKN1A, and BAX and Downregulation of Antiapoptotic Gene BCL2. International journal of medicinal mushrooms. vol 24. issue 8. 2022-08-23. PMID:35997095.' |
quantitative real-time polymerase chain reaction (qrt-pcr) was performed to investigate genes associated with apoptosis, included four target genes (bax, bcl2, cdkn1a, and tp53) and one reference gene (gapdh). |
2022-08-23 |
2023-08-14 |
Not clear |
| b' Kochar Khasro Saleh, Sevda Kirbag, Semih Dalk\\xc4\\xb1l\\xc4\\xb1\\xc3\\xa. Inhibitory Effects of Terfezia (Ascomycota) Desert Truffles on PANC-1 Cell Growth via Upregulation of Proapoptotic Genes TP53, CDKN1A, and BAX and Downregulation of Antiapoptotic Gene BCL2. International journal of medicinal mushrooms. vol 24. issue 8. 2022-08-23. PMID:35997095.' |
based on qrt-pcr, each extract reduced the progress of panc-1 cells by inducing apoptosis, denoted by the upregulation of the proapoptotic genes bax, cdkn1a, and tp53 and downregulation of the antiapoptotic gene bcl2. |
2022-08-23 |
2023-08-14 |
Not clear |
| Praveen K Sobhan, Mahendra Seervi, Lokesh Deb, Saneesh Varghese, Anjana Soman, Jeena Joseph, Krupa Ann Mathew, Godi Raghu, George Thomas, E Sreekumar, S Manjula, T R Santosh Kuma. Correction: Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis. PloS one. vol 17. issue 8. 2022-08-23. PMID:35998139. |
correction: calpain and reactive oxygen species targets bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis. |
2022-08-23 |
2023-08-14 |
Not clear |