| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tieg. TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 10. 2007-12-27. PMID:17982095. |
tnf pretreatment interferes with mitochondrial apoptosis in the mouse liver by a20-mediated down-regulation of bax. |
2007-12-27 |
2023-08-12 |
mouse |
| Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tieg. TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 10. 2007-12-27. PMID:17982095. |
our results show that pretreatment with tnf, or application of small-interfering rna directed against the proapoptotic bcl2 family member bax, interfered with the onset of mitochondrial apoptosis in vivo. |
2007-12-27 |
2023-08-12 |
mouse |
| Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tieg. TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 10. 2007-12-27. PMID:17982095. |
knockdown of tnf-alpha-induced-protein 3 (a20) restored mitochondrial apoptosis, bax expression, and liver damage. |
2007-12-27 |
2023-08-12 |
mouse |
| Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tieg. TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 10. 2007-12-27. PMID:17982095. |
the underlying mechanism of protection seems to involve a cascade of events, where tnf induces the expression of a20 in hepatocytes, a20 down-modulates bax expression by interference with transcriptional activation, and the reduced availability of bax interferes with the onset of mitochondrial apoptosis and the ensuing apoptotic liver damage. |
2007-12-27 |
2023-08-12 |
mouse |
| Shucai An, Yoshitaka Hishikawa, Jie Liu, Takehiko Koj. Lung injury after ischemia-reperfusion of small intestine in rats involves apoptosis of type II alveolar epithelial cells mediated by TNF-alpha and activation of Bid pathway. Apoptosis : an international journal on programmed cell death. vol 12. issue 11. 2007-12-21. PMID:17786556. |
here, we investigated the mechanisms of apoptosis including the expression of fas, fas ligand (fasl), bid, bax, bcl-2, cytochrome c, and activated caspase-3 in the rat lung at various time-points (0-24 h) of reperfusion after 1-h ischemia of small intestine. |
2007-12-21 |
2023-08-12 |
rat |
| Indrani Sinha-Hikim, Mellisa Braga, Ruoqing Shen, Amiya P Sinha Hiki. Involvement of c-Jun NH2-terminal kinase and nitric oxide-mediated mitochondria-dependent intrinsic pathway signaling in cardiotoxin-induced muscle cell death: role of testosterone. Apoptosis : an international journal on programmed cell death. vol 12. issue 11. 2007-12-21. PMID:17786558. |
initiation of apoptosis was preceded by jnk activation and elevated levels of b-cell lymphoma-2 (bcl-2) in the mitochondrial fractions (bax levels remained unaffected). |
2007-12-21 |
2023-08-12 |
mouse |
| Fayaz Malik, Ajay Kumar, Shashi Bhushan, Sheema Khan, Aruna Bhatia, Krishan Avtar Suri, Ghulam Nabi Qazi, Jaswant Sing. Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine. Apoptosis : an international journal on programmed cell death. vol 12. issue 11. 2007-12-21. PMID:17874299. |
the withanolide induced early ros generation and mitochondrial membrane potential (deltapsi(mt)) loss, which preceded release of cytochrome c, translocation of bax to mitochondria and apoptosis inducing factor to cell nuclei. |
2007-12-21 |
2023-08-12 |
human |
| Sahdeo Prasad, Jaspreet Kaur, Preeti Roy, Neetu Kalra, Yogeshwer Shukl. Theaflavins induce G2/M arrest by modulating expression of p21waf1/cip1, cdc25C and cyclin B in human prostate carcinoma PC-3 cells. Life sciences. vol 81. issue 17-18. 2007-12-21. PMID:17936851. |
increased exposure time to tf caused apoptosis of pc-3 cells, which was associated with up-regulation of the pro-apoptotic proteins bax, caspase-3 and caspase-9 and down-regulation of anti-apoptotic protein bcl-2. |
2007-12-21 |
2023-08-12 |
human |
| An-Xiu Xiong, Min Wang, Run-Ming Jin, Yan Bai, Wen Li. [Ouabain-induced apoptosis of Jurkat cells correlates with activation of caspase-3 and regulation of Bcl-2 gene family]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 5. 2007-12-20. PMID:17096883. |
the results showed that ouabain could induce apoptosis of jurkat cells, the expression of bax protein in process of cell apoptosis, caspase-3 activity of jurkat cells were remarkably enhanced after ouabain treatment. |
2007-12-20 |
2023-08-12 |
Not clear |
| An-Xiu Xiong, Min Wang, Run-Ming Jin, Yan Bai, Wen Li. [Ouabain-induced apoptosis of Jurkat cells correlates with activation of caspase-3 and regulation of Bcl-2 gene family]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 5. 2007-12-20. PMID:17096883. |
it is concluded that ouabain may induce apoptosis of jurkat cells due to the activation of caspase-3 resulting from regulation of bax protein and bcl-2 gene expressions. |
2007-12-20 |
2023-08-12 |
Not clear |
| Yinyuan Wu, Da Xing, Wei R Chen, Xichao Wan. Bid is not required for Bax translocation during UV-induced apoptosis. Cellular signalling. vol 19. issue 12. 2007-12-20. PMID:17855051. |
bid is not required for bax translocation during uv-induced apoptosis. |
2007-12-20 |
2023-08-12 |
human |
| Yinyuan Wu, Da Xing, Wei R Chen, Xichao Wan. Bid is not required for Bax translocation during UV-induced apoptosis. Cellular signalling. vol 19. issue 12. 2007-12-20. PMID:17855051. |
bax, a member of the bcl-2 family of proteins, translocates from the cytosol to the mitochondrial membrane during uv-induced apoptosis, but the regulation of bax translocation by uv irradiation remains elusive. |
2007-12-20 |
2023-08-12 |
human |
| Yinyuan Wu, Da Xing, Wei R Chen, Xichao Wan. Bid is not required for Bax translocation during UV-induced apoptosis. Cellular signalling. vol 19. issue 12. 2007-12-20. PMID:17855051. |
overexpression of bcl-x(l) in cells susceptible to uv-induced apoptosis prevents bax translocation and cell death, repression of bid protein with sirna (small interfering rna) do not inhibit cell death by uv irradiation. |
2007-12-20 |
2023-08-12 |
human |
| Xi-Ping Zhang, Hua Tian, Bei Lu, Li Chen, Ru-Jun Xu, Ke-Yi Wang, Zhi-Wei Wang, Qi-Hui Cheng, Hai-Ping She. Tissue microarrays in pathological examination of apoptotic acinar cells induced by dexamethasone in the pancreas of rats with severe acute pancreatitis. Hepatobiliary & pancreatic diseases international : HBPD INT. vol 6. issue 5. 2007-12-20. PMID:17897919. |
this study was designed to investigate the influence of dexamethasone on apoptosis of acinar cells in the pancreas of rats with sap and the protein expression of the apoptosis-regulating genes bax and bcl-2. |
2007-12-20 |
2023-08-12 |
rat |
| Masayasu Iwase, Sayaka Yoshiba, Makiko Uchid, Sayaka Takaoka, Yuji Kurihara, Daisuke Ito, Masashi Hatori, Satoru Shintan. Enhanced susceptibility to apoptosis of oral squamous cell carcinoma cells subjected to combined treatment with anticancer drugs and phosphatidylinositol 3-kinase inhibitors. International journal of oncology. vol 31. issue 5. 2007-12-20. PMID:17912441. |
expression of bcl-2, cellular inhibitor of apoptosis protein-1 (ciap-1), and x-linked iap was down-regulated, and expression of bax was up-regulated by pi 3-k inhibitors, while that of bcl-xl, bak and ciap-2 was not attenuated. |
2007-12-20 |
2023-08-12 |
Not clear |
| Donna Amrán, Yolanda Sánchez, Carlos Fernández, Adrián M Ramos, Elena de Blas, Jacqueline Bréard, Consuelo Calle, Patricio Alle. Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways. Biochimica et biophysica acta. vol 1773. issue 11. 2007-12-19. PMID:17673311. |
p38-mapk-specific inhibitors attenuate the as(2)o(3) plus tnfalpha-provoked activation of caspase-8/bid, bax translocation, cytochrome c release, and apoptosis induction. |
2007-12-19 |
2023-08-12 |
human |
| Xiao-Ming Guo, Qing Lu, Zheng-Juan Liu, Li-Feng Wang, Bing-An Fen. [Effects of D-limonene on leukemia cells HL-60 and K562 in vitro]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 4. 2007-12-18. PMID:16928301. |
to investigate the effects of d-limonene (d-l) on the cell growth and apoptosis in hl-60, k562 cells and to elucidate its mechanism, the influence of d-l on proliferation of hl-60 and k562 cells was determined by propidium iodide assay, the expression levels of mutant p53, bcl-2, bax gene were detected by cell morphological analysis, flow cytometry and immunohistochemistry staining, the d-l-inducing hl-60 and k562 cell apoptosis in vitro was observed systematically. |
2007-12-18 |
2023-08-12 |
Not clear |
| Xiao-Ming Guo, Qing Lu, Zheng-Juan Liu, Li-Feng Wang, Bing-An Fen. [Effects of D-limonene on leukemia cells HL-60 and K562 in vitro]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 4. 2007-12-18. PMID:16928301. |
the bcl-2, mutant type of p53 and bax may be involved in the gene regulation of d-l-induced apoptosis. |
2007-12-18 |
2023-08-12 |
Not clear |
| Thucydides L Salunga, Zheng-Guo Cui, Shinji Shimoda, Hua-Chuan Zheng, Kazuhiro Nomoto, Takashi Kondo, Yasuo Takano, Carlo Selmi, Gianfranco Alpini, M Eric Gershwin, Koichi Tsuneyam. Oxidative stress-induced apoptosis of bile duct cells in primary biliary cirrhosis. Journal of autoimmunity. vol 29. issue 2-3. 2007-12-18. PMID:17544621. |
furthermore, we studied the influence of hocl on apoptosis in cultured human biliary epithelial cells (bec) as well as the associated activity of bcl-2, bax, p-jnk, jnk, p53, fas and caspase-3. |
2007-12-18 |
2023-08-12 |
human |
| Bernhard Gillissen, Frank Essmann, Philipp G Hemmati, Antje Richter, Anja Richter, Ilker Oztop, Govindaswamy Chinnadurai, Bernd Dörken, Peter T Danie. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis. The Journal of cell biology. vol 179. issue 4. 2007-12-18. PMID:18025305. |
mcl-1 determines the bax dependency of nbk/bik-induced apoptosis. |
2007-12-18 |
2023-08-12 |
Not clear |