| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jose A Aquino Esperanza, Maria V Aguirre, Gualberto R Aispuru, Carolina N Lettieri, Julian A Juaristi, Mirta A Alvarez, Nora Cristina Branda. In vivo 5-fluorouracil-[corrected]induced apoptosis on murine thymocytes: involvement of FAS, Bax and Caspase3. Cell biology and toxicology. vol 24. issue 5. 2008-10-17. PMID:18266059. |
in vivo 5-fluorouracil-[corrected]induced apoptosis on murine thymocytes: involvement of fas, bax and caspase3. |
2008-10-17 |
2023-08-12 |
mouse |
| Jose A Aquino Esperanza, Maria V Aguirre, Gualberto R Aispuru, Carolina N Lettieri, Julian A Juaristi, Mirta A Alvarez, Nora Cristina Branda. In vivo 5-fluorouracil-[corrected]induced apoptosis on murine thymocytes: involvement of FAS, Bax and Caspase3. Cell biology and toxicology. vol 24. issue 5. 2008-10-17. PMID:18266059. |
this study revealed that in vivo apoptosis in normal thymus after 5-fu administration is related to fas, bax, and caspase 3 co-expressions under the current experimental conditions, these findings, therefore, contribute to a new insight into the molecular mechanisms involved during 5-fu administration upon the thymus and the possible events committed in the lymphophenia associated with chemotherapy. |
2008-10-17 |
2023-08-12 |
mouse |
| Kentaro Aoki, Mari Egawa, Takeshi Saito, Toshiyuki Hosokawa, Masaaki Kurasak. Effects of gamma-hexachlorocyclohexane on apoptosis induced by serum deprivation in PC12 cells. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. vol 43. issue 6. 2008-10-15. PMID:18665982. |
although gamma -hch at high concentration did not have an effect on cell viability and apoptosis, dna fragmentation was slightly enhanced, and apoptotic factors; bax, bad, cytochrome c and caspase-3 showed tendency to increase by the addition of a low dose of gamma-hch to the cell medium. |
2008-10-15 |
2023-08-12 |
Not clear |
| L Susini, S Besse, D Duflaut, A Lespagnol, C Beekman, G Fiucci, A R Atkinson, D Busso, P Poussin, J-C Marine, J-C Martinou, J Cavarelli, D Moras, R Amson, A Telerma. TCTP protects from apoptotic cell death by antagonizing bax function. Cell death and differentiation. vol 15. issue 8. 2008-10-14. PMID:18274553. |
we found a structural similarity between the h2-h3 helices of tctp and the h5-h6 helices of bax, which have been previously implicated in regulating the mitochondrial membrane permeability during apoptosis. |
2008-10-14 |
2023-08-12 |
mouse |
| L Susini, S Besse, D Duflaut, A Lespagnol, C Beekman, G Fiucci, A R Atkinson, D Busso, P Poussin, J-C Marine, J-C Martinou, J Cavarelli, D Moras, R Amson, A Telerma. TCTP protects from apoptotic cell death by antagonizing bax function. Cell death and differentiation. vol 15. issue 8. 2008-10-14. PMID:18274553. |
finally, we show that tctp antagonizes apoptosis by inserting into the mitochondrial membrane and inhibiting bax dimerization. |
2008-10-14 |
2023-08-12 |
mouse |
| A J Valentijn, J-P Upton, N Bates, A P Gilmor. Bax targeting to mitochondria occurs via both tail anchor-dependent and -independent mechanisms. Cell death and differentiation. vol 15. issue 8. 2008-10-14. PMID:18437166. |
interestingly, we find that bax mutants, which themselves cannot target mitochondria or induce apoptosis, are recruited to clusters of activated wild-type bax on the omm of apoptotic cells. |
2008-10-14 |
2023-08-12 |
zebrafish |
| Yi Luo, Wafi Waladali, Shiwen Li, Xinmin Zheng, Liquan Hu, Hang Zheng, Wanli Hu, Chan Che. 17beta-estradiol affects proliferation and apoptosis of rat prostatic smooth muscle cells by modulating cell cycle transition and related proteins. Cell biology international. vol 32. issue 8. 2008-10-14. PMID:18474438. |
the progression of cell cycle, cellular apoptosis, cyclin d1, bcl-2 and bax proteins were detected. |
2008-10-14 |
2023-08-12 |
rat |
| Yi Luo, Wafi Waladali, Shiwen Li, Xinmin Zheng, Liquan Hu, Hang Zheng, Wanli Hu, Chan Che. 17beta-estradiol affects proliferation and apoptosis of rat prostatic smooth muscle cells by modulating cell cycle transition and related proteins. Cell biology international. vol 32. issue 8. 2008-10-14. PMID:18474438. |
the data show that the effect of e2 on rat psmcs is bilateral: it promotes cell proliferation by enhancing the expression of cyclin d1, which accelerates g1 to s phase transition; on the other hand, it induces apoptosis of the cells by up-regulating the expression of bax. |
2008-10-14 |
2023-08-12 |
rat |
| Gualberto Rodrigo Aispuru, María Victoria Aguirre, José Andrés Aquino-Esperanza, Carolina Noelia Lettieri, Julián Antonio Juaristi, Nora Cristina Branda. Erythroid expansion and survival in response to acute anemia stress: the role of EPO receptor, GATA-1, Bcl-xL and caspase-3. Cell biology international. vol 32. issue 8. 2008-10-14. PMID:18485751. |
apoptosis (tunel assay), bm architecture organization (scanning electronic microscopy), proliferation (dna assay), differentiation (clonogenic cultures), expression of survival erythroid related proteins (epo-r, gata-1, bcl-xl) as well as the expression of apoptotic- related proteins (bax, activated caspase-3) by western blotting, were evaluated. |
2008-10-14 |
2023-08-12 |
mouse |
| Luís Sánchez-del-Campo, José Neptuno Rodríguez-Lópe. Targeting the methionine cycle for melanoma therapy with 3-O-(3,4,5-trimethoxybenzoyl)-(-)-epicatechin. International journal of cancer. vol 123. issue 10. 2008-10-10. PMID:18729182. |
tmecg treatment of melanoma cells resulted in the downregulation of antiapoptotic bcl-2, the upregulation of proapoptotic bax and the activation of caspase-3; however, it did not induce the expression of the apoptosis protease-activating factor-1 (apaf-1). |
2008-10-10 |
2023-08-12 |
Not clear |
| Eun Joo Jung, Deok Ryong Ki. Apoptotic cell death in TrkA-overexpressing cells: kinetic regulation of ERK phosphorylation and caspase-7 activation. Molecules and cells. vol 26. issue 1. 2008-10-09. PMID:18511888. |
furthermore, the truncated form (p18) of bax accumulated in the trka-induced cells, suggesting that trka induces mitochondria-mediated apoptosis. |
2008-10-09 |
2023-08-12 |
Not clear |
| Kensuke Kojima, Marina Konopleva, Twee Tsao, Hideki Nakakuma, Michael Andreef. Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia. Blood. vol 112. issue 7. 2008-10-09. PMID:18633130. |
mk-0457 and nutlin-3 showed synergism in inducing p53, conformational change of bax and deltapsi(m) loss, suggesting an involvement of p53-mediated mitochondrial apoptosis. |
2008-10-09 |
2023-08-12 |
Not clear |
| Dubravka Cvejic, Sonja Selemetjev, Svetlana Savin, Ivan Paunovic, Ivana Petrovic, Svetislav Tati. Apoptosis and proliferation related molecules (Bcl-2, Bax, p53, PCNA) in papillary microcarcinoma versus papillary carcinoma of the thyroid. Pathology. vol 40. issue 5. 2008-10-07. PMID:18604733. |
apoptosis and proliferation related molecules (bcl-2, bax, p53, pcna) in papillary microcarcinoma versus papillary carcinoma of the thyroid. |
2008-10-07 |
2023-08-12 |
Not clear |
| Mamdooh Ghoneum, Motohiro Matsuura, Melissa Braga, Sastry Gollapud. S. cerevisiae induces apoptosis in human metastatic breast cancer cells by altering intracellular Ca2+ and the ratio of Bax and Bcl-2. International journal of oncology. vol 33. issue 3. 2008-10-07. PMID:18695883. |
s. cerevisiae induces apoptosis in human metastatic breast cancer cells by altering intracellular ca2+ and the ratio of bax and bcl-2. |
2008-10-07 |
2023-08-12 |
human |
| Mamdooh Ghoneum, Motohiro Matsuura, Melissa Braga, Sastry Gollapud. S. cerevisiae induces apoptosis in human metastatic breast cancer cells by altering intracellular Ca2+ and the ratio of Bax and Bcl-2. International journal of oncology. vol 33. issue 3. 2008-10-07. PMID:18695883. |
in conclusion, yeast induces apoptosis of human mbc cells in vitro by a mechanism involving intracellular ca2+ and bax:bcl-2. |
2008-10-07 |
2023-08-12 |
human |
| Koji Kono, Yoshihiko Kawaguchi, Yoshiki Mizukami, Kousaku Mimura, Hidemitsu Sugai, Hidenori Akaike, Hideki Fuji. Protein-bound polysaccharide K partially prevents apoptosis of circulating T cells induced by anti-cancer drug S-1 in patients with gastric cancer. Oncology. vol 74. issue 3-4. 2008-10-07. PMID:18708731. |
in order to evaluate whether concomitant administration of the oral biological response modifier protein-bound polysaccharide k (psk) could induce anti-apoptotic effects in patients treated with the anti-cancer drug, s-1, peripheral blood t cells were analyzed for induction of apoptosis, caspase-3 activities and expression of proapoptotic protein bax and anti-apoptotic protein bcl-2 in patients with curatively resected stage iii gastric cancer, who were randomly assigned to postoperative adjuvant therapy with s-1 alone (n = 10) or s-1 combined with psk (n = 10). |
2008-10-07 |
2023-08-12 |
Not clear |
| Lili Wei, Zhongtang Wang, Tao Cui, Faping Yi, Youquan Bu, Songtao Ding, Yongping Ma, Fangzhou Son. Proteomic analysis of cervical cancer cells treated with adenovirus-mediated MDA-7. Cancer biology & therapy. vol 7. issue 4. 2008-10-06. PMID:18299662. |
a total of 43 differentially expressed proteins were visualized by 2-de and silver stain., 29 proteins of which were identified via matrix-assisted laser desorption/ionization-time of flight mass spectrometry(maldi-tof-ms) analysis, 15 were upregulated (eg., tumor suppressor p53, apoptosis regulator bax, adenylate kinase isoenzyme 1(ak1), growth arrest and dna-damage-inducible protein gadd45 gamma (gadd45gamma)) and 14 were downregulated (e.g., eukaryotic translation initiation factor 5a(eif-5a), protein dj-1, annexin v, transcription elongation factor b polypeptide 2 (tceb2), traf family member-associated nfkappab activator (traf2),c-myc-responsive protein rcl (rcl)). |
2008-10-06 |
2023-08-12 |
human |
| Lykke Grubach, Caroline Juhl-Christensen, Anita Rethmeier, Lene Hyldahl Olesen, Anni Aggerholm, Peter Hokland, Mette Ostergaar. Gene expression profiling of Polycomb, Hox and Meis genes in patients with acute myeloid leukaemia. European journal of haematology. vol 81. issue 2. 2008-10-06. PMID:18410541. |
comparisons between the pcg and pcg-regulated genes and a number of clinical and molecular data revealed correlations to genes involved in dna methylation (dnmt1, dnmt3b), apoptosis (bax, caspase 3) and multidrug-resistance (mdr1, mrp ) (p < 0.01). |
2008-10-06 |
2023-08-12 |
Not clear |
| Julie L Wilsbacher, Qian Zhang, Lora A Tucker, Robert D Hubbard, George S Sheppard, Nwe Y Bamaung, Steve D Fidanze, Gary T Wang, Xiaoming Hu, Steven K Davidsen, Randy L Bell, Jieyi Wan. Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation. The Journal of biological chemistry. vol 283. issue 35. 2008-10-03. PMID:18559346. |
insulin-like growth factor-1 receptor and erbb kinase inhibitor combinations block proliferation and induce apoptosis through cyclin d1 reduction and bax activation. |
2008-10-03 |
2023-08-12 |
Not clear |
| Julie L Wilsbacher, Qian Zhang, Lora A Tucker, Robert D Hubbard, George S Sheppard, Nwe Y Bamaung, Steve D Fidanze, Gary T Wang, Xiaoming Hu, Steven K Davidsen, Randy L Bell, Jieyi Wan. Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation. The Journal of biological chemistry. vol 283. issue 35. 2008-10-03. PMID:18559346. |
thus, targeting both igf-1r and erbb receptors simultaneously results in cell cycle arrest and apoptosis through combined effects on akt, cyclin d1, and bax activation. |
2008-10-03 |
2023-08-12 |
Not clear |