| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pierre-François Cartron, Grégory Bellot, Lisa Oliver, Xavier Grandier-Vazeille, Stephen Manon, François M Vallett. Bax inserts into the mitochondrial outer membrane by different mechanisms. FEBS letters. vol 582. issue 20. 2008-10-31. PMID:18687331. |
bax insertion into the mitochondrial outer membrane is essential for the implementation of apoptosis. |
2008-10-31 |
2023-08-12 |
Not clear |
| Chunlei Zhang, Baoqiang Li, Amos S Gaikwad, Valsala Haridas, Zhixiang Xu, Jordan U Gutterman, Madeleine Duvi. Avicin D selectively induces apoptosis and downregulates p-STAT-3, bcl-2, and survivin in cutaneous T-cell lymphoma cells. The Journal of investigative dermatology. vol 128. issue 11. 2008-10-30. PMID:18496567. |
avicin d also decreased expression of the inhibitor of apoptosis protein survivin, the anti-apoptotic protein bcl-2, but not the pro-apoptotic protein bax in these ctcl cells. |
2008-10-30 |
2023-08-12 |
mouse |
| Bojana Zegura, Irena Zajc, Tamara T Lah, Metka Filipi. Patterns of microcystin-LR induced alteration of the expression of genes involved in response to DNA damage and apoptosis. Toxicon : official journal of the International Society on Toxinology. vol 51. issue 4. 2008-10-28. PMID:18191168. |
the increased ratio of expression of bax to that of bcl-2 induced by mclr suggests that apoptosis in hepg2 cells proceeds via the mitochondrial pathway. |
2008-10-28 |
2023-08-12 |
Not clear |
| Munetaka Ozeki, John E Shivel. Differential cell fates induced by all-trans retinoic acid-treated HL-60 human leukemia cells. Journal of leukocyte biology. vol 84. issue 3. 2008-10-28. PMID:18552205. |
analysis of several proapoptotic proteins implicated the activation of calpain and cleavage of bax in the intrinsic apoptotic pathway, similar to published studies about the apoptosis of neutrophils. |
2008-10-28 |
2023-08-12 |
human |
| Tae Oh Kwon, Seung-Il Jeong, Ji Wung Kwon, Youn Chul Kim, Seon Il Jan. Continentalic acid from Aralia continentalis induces growth inhibition and apoptosis in HepG2 cells. Archives of pharmacal research. vol 31. issue 9. 2008-10-28. PMID:18806961. |
the induction of apoptosis in hepg2 cells by ca was mediated through the activation of caspase-3, bak, and bax, and then through the cleavage of peroxisome proliferator-activated receptor (parp) and the down-regulation of bcl-2. |
2008-10-28 |
2023-08-12 |
Not clear |
| Ming-Luan Xing, Xiao-Feng Wang, Li-Hong X. Alteration of proteins expression in apoptotic FL cells induced by MCLR. Environmental toxicology. vol 23. issue 4. 2008-10-27. PMID:18214937. |
the present study was undertaken to determine the expression of pp2a, chop, bax, bcl-2, and p53 proteins in mclr-induced apoptosis in fl cells. |
2008-10-27 |
2023-08-12 |
Not clear |
| Ming-Luan Xing, Xiao-Feng Wang, Li-Hong X. Alteration of proteins expression in apoptotic FL cells induced by MCLR. Environmental toxicology. vol 23. issue 4. 2008-10-27. PMID:18214937. |
the results showed that mclr could induce apoptosis in fl cells and the process was accompanied with the upregulation of pp2a, bax, and p53 proteins and the downregulation of bcl-2 proteins. |
2008-10-27 |
2023-08-12 |
Not clear |
| Cecilia Bivik, Karin Ollinge. JNK mediates UVB-induced apoptosis upstream lysosomal membrane permeabilization and Bcl-2 family proteins. Apoptosis : an international journal on programmed cell death. vol 13. issue 9. 2008-10-27. PMID:18651223. |
depletion of both jnk1 and jnk2 expression using sirna transfection, protected against apoptosis, as detected by decreased nuclear fragmentation and caspase-3 activity, as well as reduced translocation of bax to mitochondria. |
2008-10-27 |
2023-08-12 |
human |
| Sang Hee Han, Moonil Kim, Kyoungsook Park, Tae-Hyoung Kim, Dai-Wu Seo. Blockade of processing/activation of caspase-3 by hypoxia. Biochemical and biophysical research communications. vol 375. issue 4. 2008-10-27. PMID:18761322. |
we have demonstrated for the first time that hypoxia inhibits trail-induced apoptosis by blocking translocation of bax from cytosol to the mitochondria in tumor cells. |
2008-10-27 |
2023-08-12 |
Not clear |
| Sang Hee Han, Moonil Kim, Kyoungsook Park, Tae-Hyoung Kim, Dai-Wu Seo. Blockade of processing/activation of caspase-3 by hypoxia. Biochemical and biophysical research communications. vol 375. issue 4. 2008-10-27. PMID:18761322. |
however, it is largely unknown how hypoxia-inhibited bax translocation attenuates trail-induced apoptosis. |
2008-10-27 |
2023-08-12 |
Not clear |
| Ildikò Szabó, Jürgen Bock, Heike Grassmé, Matthias Soddemann, Barbara Wilker, Florian Lang, Mario Zoratti, Erich Gulbin. Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 39. 2008-10-24. PMID:18818304. |
here, we show that mouse and human cells either genetically deficient in kv1.3 or transfected with sirna to suppress kv1.3-expression resisted apoptosis induced by several stimuli, including bax over-expression [corrected]. |
2008-10-24 |
2023-08-12 |
mouse |
| Wen-Horng Wang, Ronald L Hullinger, Ourania M Andrisan. Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis. The Journal of biological chemistry. vol 283. issue 37. 2008-10-23. PMID:18606816. |
the p38mapk pathway also activates atr, leading to phosphorylation of p53 on ser-18 and ser-23, transcription of pro-apoptotic genes bax, fas, and noxa, and apoptosis. |
2008-10-23 |
2023-08-12 |
Not clear |
| Xiaofeng Zhang, Xiaoyan Kang, Lehua Shi, Jin Li, Wen Xu, Haihua Qian, Mengchao Wu, Zhengfeng Yi. mda-7/IL-24 induces apoptosis in human HepG2 hepatoma cells by endoplasmic reticulum stress. Oncology reports. vol 20. issue 2. 2008-10-22. PMID:18636209. |
we found that blocking the endoplasmic reticulum (er) stress inhibited apoptosis induced by ad.mda-7 and down-regulated the expression of caspase-12, bax and caspase-3. |
2008-10-22 |
2023-08-12 |
human |
| Luigia Longo, Francesca Platini, Anna Scardino, Oscar Alabiso, Giuseppe Vasapollo, Luciana Tessitor. Autophagy inhibition enhances anthocyanin-induced apoptosis in hepatocellular carcinoma. Molecular cancer therapeutics. vol 7. issue 8. 2008-10-22. PMID:18723493. |
anthocyanin-induced autophagy switched to apoptosis, as shown by the activation of bax, cytochrome c and caspase 3, terminal deoxynucleotide transferase-mediated dutp nick-end labeling-positive fragmented nuclei, and cells with sub-g(1) dna content, which were prevented by z-vad. |
2008-10-22 |
2023-08-12 |
Not clear |
| Ji-Hui Hao, Ming Yu, Li Jia, Feng-Ting Liu, Qiang Li, Xi-Shan Ha. [The modulating effect of proapoptotic protein Bax on the resistance of malignant lymphoma cells to tumor necrosis factor related apoptosis inducing ligand-induced apoptosis]. Zhonghua yi xue za zhi. vol 87. issue 2. 2008-10-21. PMID:17418025. |
[the modulating effect of proapoptotic protein bax on the resistance of malignant lymphoma cells to tumor necrosis factor related apoptosis inducing ligand-induced apoptosis]. |
2008-10-21 |
2023-08-12 |
Not clear |
| Ji-Hui Hao, Ming Yu, Li Jia, Feng-Ting Liu, Qiang Li, Xi-Shan Ha. [The modulating effect of proapoptotic protein Bax on the resistance of malignant lymphoma cells to tumor necrosis factor related apoptosis inducing ligand-induced apoptosis]. Zhonghua yi xue za zhi. vol 87. issue 2. 2008-10-21. PMID:17418025. |
to elucidate the modulating effect of proapoptotic protein bax on the resistance of malignant lymphoma cells to tumor necrotic factor-related apoptosis inducing ligand (trail)-induced apoptosis and offer evidence for clinic work. |
2008-10-21 |
2023-08-12 |
Not clear |
| Cheol Park, Hee Jae Shin, Gi-Young Kim, Taeg Kyu Kwon, Taek-Jeong Nam, Se-Kwon Kim, Jaehun Cheong, Il-Whan Choi, Yung Hyun Cho. Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 22. issue 6. 2008-10-21. PMID:18639625. |
the increase in apoptosis that was induced by streptochlorin was correlated with down-regulation of anti-apoptotic bcl-2 expression, up-regulation of pro-apoptotic bax and fasl, a decrease in the mitochondrial membrane potential (mmp), activation of caspases and degradation of poly-(adp-ribose)polymerase and phospholipase c-gamma1 protein. |
2008-10-21 |
2023-08-12 |
human |
| Vasileia-Ismini Alexaki, Delphine Javelaud, Alain Mauvie. JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis. Pigment cell & melanoma research. vol 21. issue 4. 2008-10-20. PMID:18541008. |
in 1205lu cells, jnk inhibition induced cell cycle arrest through p53-dependent induction of p21 cip1/waf1 expression, while in wm983b cells, induction of apoptosis by jnk inhibition was accompanied by p53, bad and bax induction, not p21 cip1/waf1. |
2008-10-20 |
2023-08-12 |
human |
| Chun Chu, Aaron J Shatki. Apoptosis and autophagy induction in mammalian cells by small interfering RNA knockdown of mRNA capping enzymes. Molecular and cellular biology. vol 28. issue 19. 2008-10-20. PMID:18678651. |
induction of apoptosis was independent of p53 tumor suppressor but dependent on bak or bax. |
2008-10-20 |
2023-08-12 |
mouse |
| Chun Chu, Aaron J Shatki. Apoptosis and autophagy induction in mammalian cells by small interfering RNA knockdown of mRNA capping enzymes. Molecular and cellular biology. vol 28. issue 19. 2008-10-20. PMID:18678651. |
in contrast to capping enzyme knockdown, apoptosis induced by cycloheximide inhibition of protein synthesis required bak but not bax. |
2008-10-20 |
2023-08-12 |
mouse |