| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuzhen Liang, Muxun Zhang, Ning Xia, Yuelian Yang, Leping Fen. Effects of high concentration glucose on the expression of NF-kappaB, Bax and cytochrome C and apoptosis of islet cells in mice. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 29. issue 4. 2011-06-06. PMID:19662359. |
the results showed that in g1, g2 and g3 groups, insulin secretion was enhanced with the increase of glucose concentration, and the nf-kappab expression was also increased (p<0.05), but bax activity, cyt c release and apoptosis rate showed no significant difference among them. |
2011-06-06 |
2023-08-12 |
mouse |
| Yuzhen Liang, Muxun Zhang, Ning Xia, Yuelian Yang, Leping Fen. Effects of high concentration glucose on the expression of NF-kappaB, Bax and cytochrome C and apoptosis of islet cells in mice. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 29. issue 4. 2011-06-06. PMID:19662359. |
however, in g4, g5, and g6 groups, apoptosis rate of islet cells, nf-kappab expression, bax activity, and cyt c release were all significantly increased, and insulin secretion was impaired as compared with g1, g2, and g3 groups (p<0.05). |
2011-06-06 |
2023-08-12 |
mouse |
| Hongmei Liu, Lijun Ma, Jizhen Wu, Kai Wang, Xianliang Che. Apoptosis of alveolar wall cells in chronic obstructive pulmonary disease patients with pulmonary emphysema is involved in emphysematous changes. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 29. issue 4. 2011-06-06. PMID:19662364. |
up-regulation of bax expression may be responsible for the apoptosis of alveolar wall cells in the copd patients with pulmonary emphysema. |
2011-06-06 |
2023-08-12 |
human |
| Kumi Kawai, Takayuki Itoh, Aki Itoh, Makoto Horiuchi, Kouji Wakayama, Peter Bannerman, James Y Garbern, David Pleasure, Tullia Lindste. Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK. The European journal of neuroscience. vol 30. issue 11. 2011-06-06. PMID:20128842. |
highly purified oligodendroglial lineage cells from mice lacking functional bax and bak genes were resistant to apoptosis after in-vitro differentiation, indicating an essential role of the intrinsic apoptotic pathway in apoptosis of oligodendrocytes in the absence of neurons (axons) and other glial cells. |
2011-06-06 |
2023-08-12 |
mouse |
| Zhihong Chen, Daofeng Ni, Yang Gao, Jiayou Li. [Apoptosis related genes--Bcl-2, bax and iNOS, expressed in the olfactory epithelium of mice infected with influenza virus]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 21. issue 11. 2011-06-02. PMID:17674769. |
[apoptosis related genes--bcl-2, bax and inos, expressed in the olfactory epithelium of mice infected with influenza virus]. |
2011-06-02 |
2023-08-12 |
mouse |
| Zhihong Chen, Daofeng Ni, Yang Gao, Jiayou Li. [Apoptosis related genes--Bcl-2, bax and iNOS, expressed in the olfactory epithelium of mice infected with influenza virus]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 21. issue 11. 2011-06-02. PMID:17674769. |
to study the expression of apoptosis related genes, bcl-2, bax, and inos in the olfactory epithelium of mice infected with influenza virus, and to discuss how they regulate apoptosis of the olfactory sensory neurons. |
2011-06-02 |
2023-08-12 |
mouse |
| H Y Jang, S J Ji, Y H Kim, H Y Lee, J S Shin, H T Cheong, J T Kim, I C Park, H S Kong, C K Park, B K Yan. Antioxidative effects of astaxanthin against nitric oxide-induced oxidative stress on cell viability and gene expression in bovine oviduct epithelial cell and the developmental competence of bovine IVM/IVF embryos. Reproduction in domestic animals = Zuchthygiene. vol 45. issue 6. 2011-06-02. PMID:19930137. |
we examined the effects of astaxanthin against nitric oxide-induced oxidative stress on cell viability by mtt assay, lipid peroxidation (lpo) by using thiobarbituric acid (tba) reaction for malondialdehyde (mda) and the expression of antioxidant genes (cuznsod, mnsod and catalase) or apoptosis genes (bcl-2, caspase-3 and bax) by rt-pcr in boec. |
2011-06-02 |
2023-08-12 |
cattle |
| Xi Wang, Hongwei Cai, Xia Yan, Zhi Y. [Effect of different tidal volume ventilation on apoptosis and the expression of Bax and Bcl-2 in rat lungs]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 35. issue 4. 2011-06-01. PMID:20448358. |
[effect of different tidal volume ventilation on apoptosis and the expression of bax and bcl-2 in rat lungs]. |
2011-06-01 |
2023-08-12 |
rat |
| Xi Wang, Hongwei Cai, Xia Yan, Zhi Y. [Effect of different tidal volume ventilation on apoptosis and the expression of Bax and Bcl-2 in rat lungs]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 35. issue 4. 2011-06-01. PMID:20448358. |
to determine the effect of different tidal volume(vt) ventilation on apoptosis and the expression of bax and bcl-2 in rat lungs. |
2011-06-01 |
2023-08-12 |
rat |
| Ching-Hsein Chen, Yu-Jia Chang, Maurice S B Ku, King-Thom Chung, Jen-Tsung Yan. Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation. Journal of molecular medicine (Berlin, Germany). vol 89. issue 3. 2011-06-01. PMID:21340685. |
compared with the use of tmz or vpa alone, concurrent treatment with both drugs synergistically induced apoptosis in u87mg cells as evidenced by p53 and bax expression, mitochondrial transmembrane potential loss, reactive oxygen species production, and glutathione depletion. |
2011-06-01 |
2023-08-12 |
human |
| Yali Han, Jingcheng Miao, Weihua Sheng, Xiaohua Wang, Yingying Jing, Yunbo Shan, Tielian Liu, Wanrong Bao, Jicheng Yan. [Interleukin 24 inhibits growth and induces apoptosis of osteosarcoma cells MG-63 in vitro and in vivo]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 25. issue 10. 2011-05-31. PMID:20112699. |
more interestingly, il-24 inhibited the growth of mg-63 cells and induced apoptosis by up-regulation of bax, caspase-3 and down-regulation of bcl-2. |
2011-05-31 |
2023-08-12 |
mouse |
| Wanrong Bao, Jingcheng Miao, Weihua Sheng, Yunbo Shan, Zhengyi Li, Xiaohua Wang, Yingying Jing, Yali Han, Jicheng Yan. [Adenovirus mediated IL-24 gene expression suppresses gastric cancer cell growth in vitro]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 25. issue 10. 2011-05-31. PMID:20112706. |
the expression of apoptosis-related genes was future determined by semi-quantification rt-pcr; we demonstrated that the moi of 100 was the optimal infective dose in the study on adenovirus-mediated il-24 gene transfer into sgc-7901 gastric cancer cell; il-24 gene mediated by adenovirus could successfully transcribe in sgc-7901 tumor cells; ad-il-24 could significantly inhibit sgc-7901 tumor cell growth and induce apoptosis, it also can up-regulate the express of bax, caspase-3 and p53 whilst down-regulate the bcl-2 expression. |
2011-05-31 |
2023-08-12 |
human |
| S K Niture, A K Jaiswa. INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis. Cell death and differentiation. vol 18. issue 3. 2011-05-31. PMID:20865015. |
further studies showed that inrf2 enhanced etoposide-mediated accumulation of bax, increased release of cytochrome c from mitochondria, activated caspase-3/7, and enhanced dna fragmentation and apoptosis. |
2011-05-31 |
2023-08-12 |
human |
| S K Niture, A K Jaiswa. INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis. Cell death and differentiation. vol 18. issue 3. 2011-05-31. PMID:20865015. |
antioxidants antagonized bcl-2:inrf2 interaction, led to the release and stabilization of bcl-2, increased bcl-2:bax heterodimers and reduced apoptosis. |
2011-05-31 |
2023-08-12 |
human |
| I Szabò, M Soddemann, L Leanza, M Zoratti, E Gulbin. Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis. Cell death and differentiation. vol 18. issue 3. 2011-05-31. PMID:20885444. |
single-point mutations of a lysine residue change function of bax and bcl-xl expressed in bax- and bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of bax-induced apoptosis. |
2011-05-31 |
2023-08-12 |
mouse |
| I Szabò, M Soddemann, L Leanza, M Zoratti, E Gulbin. Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis. Cell death and differentiation. vol 18. issue 3. 2011-05-31. PMID:20885444. |
these data indicate a toxin-like action of bax on kv1.3 to trigger at least some of the mitochondrial changes typical for apoptosis. |
2011-05-31 |
2023-08-12 |
mouse |
| I Szabò, M Soddemann, L Leanza, M Zoratti, E Gulbin. Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis. Cell death and differentiation. vol 18. issue 3. 2011-05-31. PMID:20885444. |
transfection of double knockout (bax(-/-)/bak(-/-)) mouse embryonic fibroblasts (dko mefs) with either wild-type bax, baxk128e, or bcl-x(l)e158k showed that apoptosis induced by various stimuli was defective in dko mefs and baxk128e-transfected cells, but was recovered upon transfection with bcl-xle158k or wild-type bax. |
2011-05-31 |
2023-08-12 |
mouse |
| L Lalier, P-F Cartron, C Olivier, C Logé, G Bougras, J-M Robert, L Oliver, F M Vallett. Prostaglandins antagonistically control Bax activation during apoptosis. Cell death and differentiation. vol 18. issue 3. 2011-05-31. PMID:20966963. |
prostaglandins antagonistically control bax activation during apoptosis. |
2011-05-31 |
2023-08-12 |
Not clear |
| L Lalier, P-F Cartron, C Olivier, C Logé, G Bougras, J-M Robert, L Oliver, F M Vallett. Prostaglandins antagonistically control Bax activation during apoptosis. Cell death and differentiation. vol 18. issue 3. 2011-05-31. PMID:20966963. |
bax, which resides in an inactive form in the cytosol of healthy cells, is activated during the early stages of apoptosis and becomes associated with mitochondria through poorly understood mechanisms. |
2011-05-31 |
2023-08-12 |
Not clear |
| L Lalier, P-F Cartron, C Olivier, C Logé, G Bougras, J-M Robert, L Oliver, F M Vallett. Prostaglandins antagonistically control Bax activation during apoptosis. Cell death and differentiation. vol 18. issue 3. 2011-05-31. PMID:20966963. |
the prostaglandin e(2) (pge(2)) or its derivative pga(2) binds to bax, induces its change of conformation, and thereby triggers apoptosis. |
2011-05-31 |
2023-08-12 |
Not clear |