| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhijuan Cao, Sean S Harvey, Tonya M Bliss, Michelle Y Cheng, Gary K Steinber. Inflammatory Responses in the Secondary Thalamic Injury After Cortical Ischemic Stroke. Frontiers in neurology. vol 11. 2021-12-07. PMID:32318016. |
in this review, we discussed emerging studies that characterized the pathological changes in the secondary degenerative thalamus after stroke; these included excitotoxicity, apoptosis, amyloid beta protein accumulation, blood-brain-barrier breakdown, and inflammatory responses. |
2021-12-07 |
2023-08-13 |
Not clear |
| Himika Wasan, Devendra Singh, Balu Joshi, Uma Sharma, A K Dinda, K H Reet. Post Stroke Safinamide Treatment Attenuates Neurological Damage by Modulating Autophagy and Apoptosis in Experimental Model of Stroke in Rats. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34453687. |
post stroke safinamide treatment attenuates neurological damage by modulating autophagy and apoptosis in experimental model of stroke in rats. |
2021-12-03 |
2023-08-13 |
rat |
| Yue Hu, Yao-Dong Dong, Yan-Chao Wu, Qiu-Xu Wang, Xiang Nan, Da-Li Wan. AMPK inhibitor BML-275 induces neuroprotection through decreasing cyt c and AIF expression after transient brain ischemia. Bioorganic & medicinal chemistry. vol 52. 2021-11-30. PMID:34837819. |
as apoptosis is an energy-dependent process with a relative time delay, abnormal energy metabolism could be a significant and fundamental pathophysiological basis of stroke. |
2021-11-30 |
2023-08-13 |
mouse |
| Shaojiong Zhou, Shuo Liu, Xiaoqiang Liu, Weiduan Zhuan. Bioinformatics Gene Analysis of Potential Biomarkers and Therapeutic Targets for Unstable Atherosclerotic Plaque-Related Stroke. Journal of molecular neuroscience : MN. vol 71. issue 5. 2021-11-19. PMID:33155176. |
inflammation, immunity, extracellular matrix degradation, blood coagulation, apoptosis and nerve degeneration were the primary physiopathological processes in uap-related stroke. |
2021-11-19 |
2023-08-13 |
Not clear |
| Lin Zhang, Wei Wei, Xiaoyu Ai, Ertugrul Kilic, Dirk M Hermann, Vivek Venkataramani, Mathias Bähr, Thorsten R Doeppne. Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway. Cell death & disease. vol 12. issue 11. 2021-11-17. PMID:34753919. |
extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the tgf-β/smad2/3 pathway. |
2021-11-17 |
2023-08-13 |
mouse |
| Ying Tian, Liang Wang, Zhiqiang Qiu, Yulun Xu, Rongrong Hu. Autophagy triggers endoplasmic reticulum stress and C/EBP homologous protein-mediated apoptosis in OGD/R-treated neurons in a caspase-12-independent manner. Journal of neurophysiology. vol 126. issue 5. 2021-11-16. PMID:34644182. |
the realization of caspase-12-independent bip-chop neuronal apoptosis pathway has expanded our understanding of the neuronal apoptosis network, which may eventually provide endogenous interventional strategies for ogd/r injury after stroke. |
2021-11-16 |
2023-08-13 |
mouse |
| Ulkan Kilic, Birsen Elibol, Merve Beker, Burcugul Altug-Tasa, Ahmet Burak Caglayan, Mustafa Caglar Beker, Bayram Yilmaz, Ertugrul Kili. Inflammatory Cytokines are in Action: Brain Plasticity and Recovery after Brain Ischemia Due to Delayed Melatonin Administration. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 30. issue 12. 2021-11-08. PMID:34547676. |
post-ischemic inflammation leads to apoptosis as an indirect cause of functional disabilities after the stroke. |
2021-11-08 |
2023-08-13 |
Not clear |
| Zahra Pourmohammadi-Bejarpasi, Amaneh Mohammadi Roushandeh, Alia Saberi, Mojdeh Kheirandish Rostami, Seyyed Mohammadtaghi Razavi Toosi, Ali Jahanian-Najafabadi, Kazuo Tomita, Yoshikazu Kuwahara, Tomoaki Sato, Mehryar Habibi Roudkena. Mesenchymal stem cells-derived mitochondria transplantation mitigates I/R-induced injury, abolishes I/R-induced apoptosis, and restores motor function in acute ischemia stroke rat model. Brain research bulletin. vol 165. 2021-10-26. PMID:33010349. |
mesenchymal stem cells-derived mitochondria transplantation mitigates i/r-induced injury, abolishes i/r-induced apoptosis, and restores motor function in acute ischemia stroke rat model. |
2021-10-26 |
2023-08-13 |
human |
| Harpreet Kaur, Deepaneeta Sarmah, Pabbala Veeresh, Aishika Datta, Kiran Kalia, Anupom Borah, Dileep R Yavagal, Pallab Bhattachary. Endovascular Stem Cell Therapy Post Stroke Rescues Neurons from Endoplasmic Reticulum Stress-Induced Apoptosis by Modulating Brain-Derived Neurotrophic Factor/Tropomyosin Receptor Kinase B Signaling. ACS chemical neuroscience. vol 12. issue 19. 2021-10-21. PMID:34553602. |
endovascular stem cell therapy post stroke rescues neurons from endoplasmic reticulum stress-induced apoptosis by modulating brain-derived neurotrophic factor/tropomyosin receptor kinase b signaling. |
2021-10-21 |
2023-08-13 |
Not clear |
| Arian Madani Neishaboori, Solmaz Nasseri Maleki, Mahdi Saberi Pirouz, Sara Golmohammadi, Donya Nazarinia, Nahid Aboutale. Donepezil attenuates injury following ischaemic stroke by stimulation of neurogenesis, angiogenesis, and inhibition of inflammation and apoptosis. Inflammopharmacology. vol 29. issue 1. 2021-10-19. PMID:33201349. |
donepezil attenuates injury following ischaemic stroke by stimulation of neurogenesis, angiogenesis, and inhibition of inflammation and apoptosis. |
2021-10-19 |
2023-08-13 |
rat |
| Enyu Liu, Haodong Sun, Jianping Wu, Yongqin Kuan. MiR-92b-3p regulates oxygen and glucose deprivation-reperfusion-mediated apoptosis and inflammation by targeting TRAF3 in PC12 cells. Experimental physiology. vol 105. issue 10. 2021-10-18. PMID:32818322. |
mir-92b-3p abated apoptosis, mitochondrial dysfunction and inflammation caused by ogd/r via targeting traf3, suggesting that mir-92b-3p may serve as a potential therapeutic target in ischaemic stroke treatment. |
2021-10-18 |
2023-08-13 |
rat |
| Zirong Pan, Guodong Ma, Linglei Kong, Guanhua D. Hypoxia-inducible factor-1: Regulatory mechanisms and drug development in stroke. Pharmacological research. vol 170. 2021-10-18. PMID:34182129. |
the regulatory mechanisms of hif-1 in stroke include inflammation, autophagy, oxidative stress, apoptosis and energy metabolism. |
2021-10-18 |
2023-08-13 |
Not clear |
| Hui Lv, Jie Li, Yuqin Ch. miR-31 from adipose stem cell-derived extracellular vesicles promotes recovery of neurological function after ischemic stroke by inhibiting TRAF6 and IRF5. Experimental neurology. vol 342. 2021-10-11. PMID:33460643. |
mir-31 from adsc-derived evs also reduced infarct volume and neuronal cell apoptosis after stroke in mice. |
2021-10-11 |
2023-08-13 |
mouse |
| Yan Zhou, Tao Tao, Guangjie Liu, Xuan Gao, Yongyue Gao, Zong Zhuang, Yue Lu, Han Wang, Wei Li, Lingyun Wu, Dingding Zhang, Chunhua Han. TRAF3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting TAK1-dependent MAPKs and NF-κB pathways. Cell death & disease. vol 12. issue 1. 2021-09-30. PMID:33414375. |
traf3 was reported as a promising therapeutic target for stroke management, which covered several neuronal apoptosis signaling cascades. |
2021-09-30 |
2023-08-13 |
mouse |
| Pingping Xia, Fan Zhang, Yajing Yuan, Cheng Chen, Yan Huang, Longyan Li, E Wang, Qulian Guo, Zhi Y. ALDH 2 conferred neuroprotection on cerebral ischemic injury by alleviating mitochondria-related apoptosis through JNK/caspase-3 signing pathway. International journal of biological sciences. vol 16. issue 8. 2021-09-24. PMID:32210721. |
thus, our study was designed to explore the influence of aldh2 in acute stroke and determine whether its related mechanisms are involved in regulating mitochondria-associated apoptosis modulating jnk/caspase-3 pathway. |
2021-09-24 |
2023-08-13 |
Not clear |
| Xin-Yin Xu, Qi Fang, Wei Huang, Bo-Cun Li, Xiao-Hong Zhou, Zhong-Yu Zhou, Jia L. Effect of Electroacupuncture on Neurological Deficit and Activity of Clock and Bmal1 in Cerebral Ischemic Rats. Current medical science. vol 40. issue 6. 2021-09-24. PMID:33428141. |
our study demonstrated that acupuncture exerted neuroprotective effect against neuronal apoptosis after stroke and the mechanism might be related with regulation of circadian rhythm proteins clock and bmal1. |
2021-09-24 |
2023-08-13 |
human |
| Yuanding Jiang, Tao Wang, Jian He, Quan Liao, Jingjing Wan. Influence of miR-1 on Nerve Cell Apoptosis in Rats with Cerebral Stroke via Regulating ERK Signaling Pathway. BioMed research international. vol 2021. 2021-09-22. PMID:34458374. |
influence of mir-1 on nerve cell apoptosis in rats with cerebral stroke via regulating erk signaling pathway. |
2021-09-22 |
2023-08-13 |
rat |
| Yuanding Jiang, Tao Wang, Jian He, Quan Liao, Jingjing Wan. Influence of miR-1 on Nerve Cell Apoptosis in Rats with Cerebral Stroke via Regulating ERK Signaling Pathway. BioMed research international. vol 2021. 2021-09-22. PMID:34458374. |
to explore the effect of mir-1 on neuronal apoptosis in rats with stroke through the erk signaling pathway. |
2021-09-22 |
2023-08-13 |
rat |
| Angeles Almeida, Irene Sánchez-Morán, Cristina Rodrígue. Mitochondrial-nuclear p53 trafficking controls neuronal susceptibility in stroke. IUBMB life. vol 73. issue 3. 2021-09-21. PMID:33615665. |
neuronal apoptosis plays an essential role in the pathophysiology of ischemic brain damage and impaired functional recovery after stroke. |
2021-09-21 |
2023-08-13 |
human |
| Angeles Almeida, Irene Sánchez-Morán, Cristina Rodrígue. Mitochondrial-nuclear p53 trafficking controls neuronal susceptibility in stroke. IUBMB life. vol 73. issue 3. 2021-09-21. PMID:33615665. |
moreover, the identification of a human single nucleotide polymorphism at codon 72 of the tp53 gene that controls p53 mitochondrial localization and cell susceptibility to apoptosis supports the important role of the p53 mitochondrial program in neuronal survival and functional recovery after stroke. |
2021-09-21 |
2023-08-13 |
human |