| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping Yang, Ye-Mei Tian, Wen-Xiang Deng, Xiong Cai, Wang-Hua Liu, Liang Li, Hui-Yong Huan. Sijunzi decoction may decrease apoptosis via stabilization of the extracellular matrix following cerebral ischaemia-reperfusion in rats. Experimental and therapeutic medicine. vol 18. issue 4. 2020-10-01. PMID:31572528. |
neurons undergo degeneration, apoptosis and death due to ischaemic stroke. |
2020-10-01 |
2023-08-13 |
rat |
| Jianhao Chen, Houwei Du, Yixian Zhang, Hongbin Chen, Mouwei Zheng, Peiqiang Lin, Quan Lan, Qilin Yuan, Yongxing Lai, Xiaodong Pan, Ronghua Chen, Nan Li. Netrin-1 Prevents Rat Primary Cortical Neurons from Apoptosis via the DCC/ERK Pathway. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:29321724. |
however, it remains blurred whether netrin-1 can protect neurons from apoptosis induced by cerebral stroke. |
2020-09-30 |
2023-08-13 |
rat |
| Li-Mei Cao, Zhi-Qiang Dong, Qiang Li, Xu Che. Treadmill training improves neurological deficits and suppresses neuronal apoptosis in cerebral ischemic stroke rats. Neural regeneration research. vol 14. issue 8. 2020-09-30. PMID:30964064. |
all training intensities reduced the neurological deficit score, infarct volume, and apoptosis in nerve cells in brain tissue of stroke rats. |
2020-09-30 |
2023-08-13 |
rat |
| Yida Wang, Zhenxiu Liu, Xinyu Ge, Xinyu Hu, Xiangyuan Cao, Lei Li, Jianhua Xia, Fulong Li, Liang Ga. Neuropathic pain releasing calcitonin gene related peptide protects against stroke in rats. American journal of translational research. vol 12. issue 1. 2020-09-28. PMID:32051737. |
the present study showed that the elevated level of calcitonin gene-related peptide-induced by npp exerts a protective effect against stroke in rats, which was further confirmed in vivo and vitro via mitigation of inflammatory response, inhibition of neuronal cell apoptosis, and increase in regional cerebral blood flow. |
2020-09-28 |
2023-08-13 |
rat |
| Yangxin Li, Jiayi Sun, Ruixia Wu, Jinrong Bai, Ya Hou, Yong Zeng, Yi Zhang, Xiaobo Wang, Zhang Wang, Xianli Men. Mitochondrial MPTP: A Novel Target of Ethnomedicine for Stroke Treatment by Apoptosis Inhibition. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32269527. |
mitochondrial mptp: a novel target of ethnomedicine for stroke treatment by apoptosis inhibition. |
2020-09-28 |
2023-08-13 |
Not clear |
| Natalia Cichon, Ewelina Synowiec, Elzbieta Miller, Tomasz Sliwinski, Michal Ceremuga, Joanna Saluk-Bijak, Michal Bija. Effect of Rehabilitation with Extremely Low Frequency Electromagnetic Field on Molecular Mechanism of Apoptosis in Post-Stroke Patients. Brain sciences. vol 10. issue 5. 2020-09-28. PMID:32366004. |
apoptosis in acute stroke is associated with a negative prognosis and is correlated with the severity of the neurological deficit. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jingyan Xiang, Xiaojie Zhang, Jianliang Fu, Hongmei Wang, Yuwu Zha. USP18 Overexpression Protects against Focal Cerebral Ischemia Injury in Mice by Suppressing Microglial Activation. Neuroscience. vol 419. 2020-09-23. PMID:31513843. |
the activation of inflammatory cytokines following stroke leads to neuron apoptosis and microglial activation, both of which are involved in ischemic brain damages. |
2020-09-23 |
2023-08-13 |
mouse |
| Rong Zhang, Weipin Zhou, Zhijun Yu, Ling Yang, Guangqi Liu, Haotian Yu, Qianyi Zhou, Zhenli Min, Chunxiang Zhang, Qingming Wu, Xia-Min Hu, Qiong Yua. miR-1247-3p mediates apoptosis of cerebral neurons by targeting caspase-2 in stroke. Brain research. vol 1714. 2020-09-17. PMID:30779911. |
mir-1247-3p mediates apoptosis of cerebral neurons by targeting caspase-2 in stroke. |
2020-09-17 |
2023-08-13 |
Not clear |
| Yi-Qiang Liang, Akemi Kakino, Yasunari Matsuzaka, Tomoji Mashimo, Masato Isono, Tomohisa Akamatsu, Hana Shimizu, Michiko Tajima, Takehito Kaneko, Lei Li, Fumihiko Takeuchi, Tatsuya Sawamura, Norihiro Kat. LOX-1 (Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) Deletion Has Protective Effects on Stroke in the Genetic Background of Stroke-Prone Spontaneously Hypertensive Rat. Stroke. vol 51. issue 6. 2020-09-14. PMID:32397936. |
recently, lox-1 (lectin-like oxidized low-density lipoprotein receptor-1), a lectin-like receptor for oxldl, has attracted attention in studies of neuronal apoptosis and stroke. |
2020-09-14 |
2023-08-13 |
rat |
| Ye-Sheng Wei, Jun Yang, Yong-Ling He, Xiang Shi, Zhi-Neng Zen. A functional polymorphism in the promoter of TUG1 is associated with an increased risk of ischaemic stroke. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-09-04. PMID:31264779. |
taurine-upregulated gene 1 (tug1), a kind of long non-coding rnas (lncrnas), was up-regulated in ischaemic stroke (is) with the function of promoting neuron apoptosis. |
2020-09-04 |
2023-08-13 |
Not clear |
| Xi'an Zhang, Zhanhui Liu, Qing Shu, Shanqi Yuan, Zhiguo Xing, Jinning Son. LncRNA SNHG6 functions as a ceRNA to regulate neuronal cell apoptosis by modulating miR-181c-5p/BIM signalling in ischaemic stroke. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-09-04. PMID:31334597. |
lncrna snhg6 functions as a cerna to regulate neuronal cell apoptosis by modulating mir-181c-5p/bim signalling in ischaemic stroke. |
2020-09-04 |
2023-08-13 |
mouse |
| Xi'an Zhang, Zhanhui Liu, Qing Shu, Shanqi Yuan, Zhiguo Xing, Jinning Son. LncRNA SNHG6 functions as a ceRNA to regulate neuronal cell apoptosis by modulating miR-181c-5p/BIM signalling in ischaemic stroke. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-09-04. PMID:31334597. |
ttc staining, quantitative real-time pcr, cell apoptosis assay, caspase-3 activity assay, western blot, rna immunoprecipitation and luciferase reporter assay were performed to evaluate the function and possible mechanisms of snhg6 in the pathogenesis of ischaemic stroke. |
2020-09-04 |
2023-08-13 |
mouse |
| Xi'an Zhang, Zhanhui Liu, Qing Shu, Shanqi Yuan, Zhiguo Xing, Jinning Son. LncRNA SNHG6 functions as a ceRNA to regulate neuronal cell apoptosis by modulating miR-181c-5p/BIM signalling in ischaemic stroke. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-09-04. PMID:31334597. |
this study revealed a novel function of snhg6 in the modulating neuronal apoptosis in the ischaemic stroke model, and the role of snhg6 in the regulating of neuronal apoptosis was at least partly via targeting mir-181c-5p/bim signalling pathway. |
2020-09-04 |
2023-08-13 |
mouse |
| Xiaoyan Yang, Peng Feng, Xiangjian Zhang, Dongfang Li, Ruifang Wang, Chenhui Ji, Guanglai Li, Christian Hölsche. The diabetes drug semaglutide reduces infarct size, inflammation, and apoptosis, and normalizes neurogenesis in a rat model of stroke. Neuropharmacology. vol 158. 2020-07-20. PMID:31465784. |
the diabetes drug semaglutide reduces infarct size, inflammation, and apoptosis, and normalizes neurogenesis in a rat model of stroke. |
2020-07-20 |
2023-08-13 |
rat |
| Masanori Gomi Naito, Daichao Xu, Palak Amin, Jinwoo Lee, Huibing Wang, Wanjin Li, Michelle Kelliher, Manolis Pasparakis, Junying Yua. Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 9. 2020-06-29. PMID:32071228. |
sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke. |
2020-06-29 |
2023-08-13 |
Not clear |
| Xue-Lin Zeng, Lu Sun, Hua-Qing Zheng, Guan-Lei Wang, Yan-Hua Du, Xiao-Fei Lv, Ming-Ming Ma, Yong-Yuan Gua. Smooth muscle-specific TMEM16A expression protects against angiotensin II-induced cerebrovascular remodeling via suppressing extracellular matrix deposition. Journal of molecular and cellular cardiology. vol 134. 2020-06-24. PMID:31301303. |
cerebrovascular remodeling is the leading factor for stroke and characterized by increased extracellular matrix deposition, migration and proliferation of vascular smooth muscle cells, and inhibition of their apoptosis. |
2020-06-24 |
2023-08-13 |
Not clear |
| Fatemeh Forouzanfar, Mana Shojapour, Samira Asgharzade, Elham Amin. Causes and Consequences of MicroRNA Dysregulation Following Cerebral Ischemia-Reperfusion Injury. CNS & neurological disorders drug targets. vol 18. issue 3. 2020-06-17. PMID:30714533. |
in this respect, the most important mechanisms underlying stroke pathophysiology are inflammatory pathways, oxidative stress, as well as apoptosis. |
2020-06-17 |
2023-08-13 |
human |
| Fatemeh Forouzanfar, Mana Shojapour, Samira Asgharzade, Elham Amin. Causes and Consequences of MicroRNA Dysregulation Following Cerebral Ischemia-Reperfusion Injury. CNS & neurological disorders drug targets. vol 18. issue 3. 2020-06-17. PMID:30714533. |
the role of mirnas involved in inflammatory pathways, oxidative stress, and apoptosis in stroke from the databases of web of science, pubmed (nlm), open access journals, lista (ebsco), and google scholar; keywords including cerebral ischemia, microrna (mirna), inflammatory pathway, oxidative stress, along with apoptosis were used. |
2020-06-17 |
2023-08-13 |
human |
| Yasunobu Okada, Tomohiro Numata, Kaori Sato-Numata, Ravshan Z Sabirov, Hongtao Liu, Shin-Ichiro Mori, Shigeru Morishim. Roles of volume-regulatory anion channels, VSOR and Maxi-Cl, in apoptosis, cisplatin resistance, necrosis, ischemic cell death, stroke and myocardial infarction. Current topics in membranes. vol 83. 2020-06-08. PMID:31196606. |
roles of volume-regulatory anion channels, vsor and maxi-cl, in apoptosis, cisplatin resistance, necrosis, ischemic cell death, stroke and myocardial infarction. |
2020-06-08 |
2023-08-13 |
Not clear |
| Akriti Srivastava, Pranay Srivastava, Rajkumar Verm. Role of bone marrow-derived macrophages (BMDMs) in neurovascular interactions during stroke. Neurochemistry international. vol 129. 2020-06-01. PMID:31145968. |
besides several pathological features, such as excitotoxicity, peri-infarct depolarization, acidosis, reactive oxygen species generation, apoptosis, and necrosis, dysregulation of the immune system severely affects stroke outcomes. |
2020-06-01 |
2023-08-13 |
Not clear |