| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stefan Roth, Jiayu Cao, Vikramjeet Singh, Steffen Tiedt, Gabriel Hundeshagen, Ting Li, Julia D Boehme, Dhruv Chauhan, Jie Zhu, Alessio Ricci, Oliver Gorka, Yaw Asare, Jun Yang, Mary S Lopez, Markus Rehberg, Dunja Bruder, Shengxiang Zhang, Olaf Groß, Martin Dichgans, Veit Hornung, Arthur Lies. Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade. Immunity. vol 54. issue 4. 2021-09-14. PMID:33667383. |
specifically, we found that stroke induced a fasl-expressing monocyte population, which led to extrinsic t cell apoptosis. |
2021-09-14 |
2023-08-13 |
Not clear |
| Shotaro Otsuka, Harutoshi Sakakima, Akira Tani, Kazuki Nakanishi, Seiya Takada, Kosuke Norimatsu, Hiroshi Maejima, Ikuro Maruyam. Effects of detraining on preconditioning exercise-induced neuroprotective potential after ischemic stroke in rats. Brain structure & function. vol 226. issue 7. 2021-08-11. PMID:34114048. |
preconditioning exercise prior to stroke exerts neuroprotection, which is an endogenous strategy that leads the brain cells to express several intrinsic factors and inhibits their apoptosis. |
2021-08-11 |
2023-08-13 |
rat |
| S G Kalinichenko, N Y Matveeva, A V Korobtso. Brain-Derived Neurotrophic Factor (BDNF) As a Regulator of Apoptosis under Conditions of Focal Experimental Stroke. Bulletin of experimental biology and medicine. vol 169. issue 5. 2021-08-09. PMID:32990850. |
brain-derived neurotrophic factor (bdnf) as a regulator of apoptosis under conditions of focal experimental stroke. |
2021-08-09 |
2023-08-13 |
rat |
| Li Lei, Shuaifeng Yang, Xiaoyang Lu, Yongfa Zhang, Tao L. Research Progress on the Mechanism of Mitochondrial Autophagy in Cerebral Stroke. Frontiers in aging neuroscience. vol 13. 2021-08-03. PMID:34335233. |
mitochondrial dysfunction during cerebral stroke involves metabolic disbalance, oxidative stress, apoptosis, endoplasmic reticulum stress, and abnormal mitochondrial autophagy. |
2021-08-03 |
2023-08-13 |
Not clear |
| Kazuo Yamagata, Yukio Yamor. Altered Properties of Neurons and Astrocytes and the Effects of Food Components in Stroke-Prone Spontaneously Hypertensive Rats. Journal of cardiovascular pharmacology. vol 77. issue 6. 2021-08-02. PMID:34001721. |
this review suggests the potential and therapeutic applications of dietary phytochemicals in reducing stroke risk and lowering blood pressure in shrsp, respectively, by targeting various processes, including oxidative stress, apoptosis, and inflammation. |
2021-08-02 |
2023-08-13 |
rat |
| Zhenhua Zhou, Ningbo Xu, Nathanael Matei, Devin W McBride, Yan Ding, Hui Liang, Jiping Tang, John H Zhan. Sodium butyrate attenuated neuronal apoptosis via GPR41/Gβγ/PI3K/Akt pathway after MCAO in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 41. issue 2. 2021-07-28. PMID:32151222. |
recent experimental evidence has suggested that sodium butyrate may be an endogenous ligand for two orphan g protein-coupled receptors, gpr41 and gp43, which regulate apoptosis and inflammation in ischemia-related pathologies, including stroke. |
2021-07-28 |
2023-08-13 |
rat |
| Yujie Li, Xucong Teng, Chunrong Yang, Yongji Wang, Lingxiao Wang, Yicong Dai, Hua Sun, Jinghong L. Ultrasound Controlled Anti-Inflammatory Polarization of Platelet Decorated Microglia for Targeted Ischemic Stroke Therapy. Angewandte Chemie (International ed. in English). vol 60. issue 10. 2021-07-20. PMID:33259112. |
satisfied prognoses were achieved with reduced apoptosis, promoted neurogenesis, and functional recovery, indicating the implications of the microglia platform for stroke therapy. |
2021-07-20 |
2023-08-13 |
Not clear |
| Yuan Zhang, Xiaotian Zhang, Qiangqiang Wei, Shuo Leng, Cai Li, Bing Han, Ying Bai, Huibin Zhang, Honghong Ya. Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke. Translational stroke research. vol 11. issue 2. 2021-07-19. PMID:31290080. |
activation of sigma-1 receptor enhanced pericyte survival via the interplay between apoptosis and autophagy: implications for blood-brain barrier integrity in stroke. |
2021-07-19 |
2023-08-13 |
mouse |
| Yuan Zhang, Xiaotian Zhang, Qiangqiang Wei, Shuo Leng, Cai Li, Bing Han, Ying Bai, Huibin Zhang, Honghong Ya. Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke. Translational stroke research. vol 11. issue 2. 2021-07-19. PMID:31290080. |
this study identified the unique roles for σ-1r in mediating pericyte survival via the regulation of the interplay between apoptosis and autophagy, suggesting that a novel σ-1r agonist may be a promising therapeutic agent for the treatment of stroke patients. |
2021-07-19 |
2023-08-13 |
mouse |
| Shu-Na Wang, Zhi Wang, Tian-Ying Xu, Ming-He Cheng, Wen-Lin Li, Chao-Yu Mia. Cerebral Organoids Repair Ischemic Stroke Brain Injury. Translational stroke research. vol 11. issue 5. 2021-07-19. PMID:31889243. |
the mechanisms underlying cos transplantation therapy are also associated with enhanced neurogenesis, synaptic reconstruction, axonal regeneration and angiogenesis, and decreased neural apoptosis with more survival neurons after stroke. |
2021-07-19 |
2023-08-13 |
rat |
| Li Sun, Ruili Han, Fei Guo, Hai Chen, Wen Wang, Zhiyang Chen, Wei Liu, Xude Sun, Changjun Ga. Antagonistic effects of IL-17 and Astragaloside IV on cortical neurogenesis and cognitive behavior after stroke in adult mice through Akt/GSK-3β pathway. Cell death discovery. vol 6. 2021-07-15. PMID:32818074. |
furthermore, il-17 ko mice and as-iv were used simultaneously to evaluate the mechanism of cell apoptosis and proliferation after stroke in vivo. |
2021-07-15 |
2023-08-13 |
mouse |
| Li Sun, Ruili Han, Fei Guo, Hai Chen, Wen Wang, Zhiyang Chen, Wei Liu, Xude Sun, Changjun Ga. Antagonistic effects of IL-17 and Astragaloside IV on cortical neurogenesis and cognitive behavior after stroke in adult mice through Akt/GSK-3β pathway. Cell death discovery. vol 6. 2021-07-15. PMID:32818074. |
moreover, as-iv treatment helped inhibit neural apoptosis, promote the neurogenesis and eventually relieve mice anxiety after stroke. |
2021-07-15 |
2023-08-13 |
mouse |
| Aysha Karim Kiani, Giacinto Abele Donato Miggiano, Barbara Aquilanti, Valeria Velluti, Giuseppina Matera, Lucilla Gagliardi, Matteo Bertell. Food supplements based on palmitoylethanolamide plus hydroxytyrosol from olive tree or Bacopa monnieri extracts for neurological diseases. Acta bio-medica : Atenei Parmensis. vol 91. issue 13-S. 2021-06-25. PMID:33170159. |
neurological disorders like parkinson disease and alzheimer disease, spinal cord injury and stroke have some recurrent characteristics such as abnormal protein aggregation, oxidative stress induction, apoptosis, excitotoxicity, perturbation of intracellular ca2+ homeostasis and inflammation. |
2021-06-25 |
2023-08-13 |
Not clear |
| Yuan Zhang, Xiaotian Zhang, Qiangqiang Wei, Shuo Leng, Cai Li, Bing Han, Ying Bai, Huibin Zhang, Honghong Ya. Correction to: Activation of Sigma-1 Receptor Enhanced Pericyte Survival Via the Interplay between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke. Translational stroke research. vol 12. issue 4. 2021-06-21. PMID:33037576. |
correction to: activation of sigma-1 receptor enhanced pericyte survival via the interplay between apoptosis and autophagy: implications for blood-brain barrier integrity in stroke. |
2021-06-21 |
2023-08-13 |
Not clear |
| Jing Wang, Haibo Tong, Xiangyang Wang, Xinxing Wang, Yang Wan. Tanshinone IIA alleviates the damage of neurocytes by targeting GLUT1 in ischaemia reperfusion model (in vivo and in vitro experiments). Folia neuropathologica. vol 58. issue 2. 2021-06-04. PMID:32729296. |
a total of 70-80% of patients experience ischaemic stroke caused by disturbances in cerebral circulation, leading to cerebral ischaemia, neuronal apoptosis, and necrosis. |
2021-06-04 |
2023-08-13 |
human |
| Wenjing Deng, Chenghe Fan, Yanan Zhao, Yuewei Mao, Jiajia Li, Yonggan Zhang, Junfang Ten. MicroRNA-130a regulates neurological deficit and angiogenesis in rats with ischaemic stroke by targeting XIAP. Journal of cellular and molecular medicine. vol 24. issue 18. 2021-06-03. PMID:32790238. |
we aim to investigate the role of mir-130a in the neurological deficit and angiogenesis in rats with ischaemic stroke by regulating x-linked inhibitor of apoptosis protein (xiap). |
2021-06-03 |
2023-08-13 |
rat |
| Peipei Zhou, Lin Zhou, Yingying Shi, Zhuolun Li, Liwei Liu, Lihua Zuo, Jun Zhang, Shuhong Liang, Jian Kang, Shuzhang Du, Jing Yang, Zhi Sun, Xiaojian Zhan. Neuroprotective Effects of Danshen Chuanxiongqin Injection Against Ischemic Stroke: Metabolomic Insights by UHPLC-Q-Orbitrap HRMS Analysis. Frontiers in molecular biosciences. vol 8. 2021-05-26. PMID:34026822. |
in our study, we focused on the neuroprotective effects of dscxq against neuroinflammatory responses and neuronal apoptosis on a stroke model based on sphingolipid metabolism. |
2021-05-26 |
2023-08-13 |
Not clear |
| Bin Chen, Wanqing Lin, Wan Qi, Shibin Li, Zhenfeng Hong, Hongjia Zha. Cofilin Inhibition by Limk1 Reduces Rod Formation and Cell Apoptosis after Ischemic Stroke. Neuroscience. vol 444. 2021-05-14. PMID:32697981. |
progressive accumulation of cofilin rods subsequently induced microtubule-associated protein-2 (map2) degradation and ischemic cell apoptosis in the infarct cortex after stroke. |
2021-05-14 |
2023-08-13 |
rat |
| Lihua Zhuang, Yingnan Kong, Shuohui Yang, Fang Lu, Zhigang Gong, Songhua Zhan, Mengxiao Li. Dynamic changes of inflammation and apoptosis in cerebral ischemia‑reperfusion injury in mice investigated by ferumoxytol‑enhanced magnetic resonance imaging. Molecular medicine reports. vol 23. issue 4. 2021-05-07. PMID:33604682. |
the severity of the inflammatory reaction and apoptosis has an important impact on the prognosis of stroke. |
2021-05-07 |
2023-08-13 |
mouse |
| Li Zhu, Xueying Zhou, Shanshan Li, Jianmeng Liu, Jingyan Yang, Xiangyun Fan, Shengnian Zho. miR‑183‑5p attenuates cerebral ischemia injury by negatively regulating PTEN. Molecular medicine reports. vol 22. issue 5. 2021-04-26. PMID:32901892. |
following transfection with agomir‑183‑5p, cerebral ischemic injury and apoptosis levels were reduced in the in vivo i/r stroke model and ogd‑induced n2a cells. |
2021-04-26 |
2023-08-13 |
mouse |