| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicolas Hugues, Caroline Pin-Barre, Thomas Brioche, Christophe Pellegrino, Eric Berton, Claudio Rivera, Jérôme Lauri. High-intensity training with short and long intervals regulate cortical neurotrophic factors, apoptosis markers and chloride homeostasis in rats with stroke. Physiology & behavior. 2023-04-13. PMID:37055005. |
high-intensity training with short and long intervals regulate cortical neurotrophic factors, apoptosis markers and chloride homeostasis in rats with stroke. |
2023-04-13 |
2023-08-14 |
rat |
| Nicolas Hugues, Caroline Pin-Barre, Thomas Brioche, Christophe Pellegrino, Eric Berton, Claudio Rivera, Jérôme Lauri. High-intensity training with short and long intervals regulate cortical neurotrophic factors, apoptosis markers and chloride homeostasis in rats with stroke. Physiology & behavior. 2023-04-13. PMID:37055005. |
hiit acts on apoptosis markers by promoting anti-apoptotic proteins in the ipsilesional cortex conclusion: : hiit regimens seem to be of clinical relevance in the critical period of stroke rehabilitation by strongly improving aerobic performance. |
2023-04-13 |
2023-08-14 |
rat |
| Airu Huang, Ling Ji, Yamei Li, Yufeng Li, Qian Y. Gut microbiome plays a vital role in post-stroke injury repair by mediating neuroinflammation. International immunopharmacology. vol 118. 2023-04-09. PMID:37031605. |
the ampk mediators have been found to exert dual roles in regulating gut microbiota and neuroinflammation/neuronal apoptosis in stroke. |
2023-04-09 |
2023-08-14 |
human |
| Andrew S Bell, Josephin Wagner, Daniel B Rosoff, Falk W Lohof. Proprotein convertase subtilisin/kexin type 9 (PCSK9) in the central nervous system. Neuroscience and biobehavioral reviews. 2023-04-05. PMID:37019248. |
among others, pcsk9 is known to play a role in neurogenesis, neural cell differentiation, central ldl receptor metabolism, neural cell apoptosis, neuroinflammation, alzheimer's disease, alcohol use disorder, and stroke. |
2023-04-05 |
2023-08-14 |
Not clear |
| Ling Chen, Su Chen, Xiao-Fei Yang, Jia-Wei Mi. Antioxidants attenuate mitochondrial oxidative damage through the Nrf2 pathway: A promising therapeutic strategy for stroke. Journal of neuroscience research. 2023-03-28. PMID:36977650. |
reactive oxygen species overproduction-induced oxidative stress in mitochondria results in mitochondrial dna damage, mitochondrial autophagy (mitophagy), inflammation, and apoptosis during the pathologic progression of stroke. |
2023-03-28 |
2023-08-14 |
Not clear |
| Jianzhuang Li, Yanmei Qiu, Chunlin Zhang, Hailing Wang, Rentang Bi, Yanhao Wei, Yanan Li, Bo H. The role of protein glycosylation in the occurrence and outcome of acute ischemic stroke. Pharmacological research. 2023-03-12. PMID:36907285. |
following ischemic stroke, the level of brain protein glycosylation becomes dynamically regulated, which significantly affects stroke outcome through influencing inflammatory response, excitotoxicity, neuronal apoptosis, and blood-brain barrier disruption. |
2023-03-12 |
2023-08-14 |
Not clear |
| Hoo Young Lee, Suk-Young Song, Jihye Hwang, Ahreum Baek, Dawoon Baek, Sung Hoon Kim, Jung Hyun Park, Sungchul Choi, Soonil Pyo, Sung-Rae Ch. Very early environmental enrichment protects against apoptosis and improves functional recovery from hypoxic-ischemic brain injury. Frontiers in molecular neuroscience. vol 15. 2023-02-24. PMID:36824441. |
few studies delineated the effect of ee on apoptosis in very early stroke in an experimental model. |
2023-02-24 |
2023-08-14 |
mouse |
| Jui-Ming Sun, Ting-Lin Yen, Jing-Shiun Jan, Pharaoh Fellow Mwale, Ruei-Dun Teng, Rajeev Taliyan, Cheng-Ta Hsieh, Chih-Hao Yan. Advances in Antibody-Based Therapeutics for Cerebral Ischemia. Pharmaceutics. vol 15. issue 1. 2023-01-21. PMID:36678774. |
when a stroke occurs, several signaling pathways are activated, comprising necrosis, apoptosis, and autophagy as well as glial activation and white matter injury, which leads to neuronal cell death. |
2023-01-21 |
2023-08-14 |
Not clear |
| Lei Zhang, Tai Zhou, Qiaorong Ji, Li He, Yan Lan, Lei Ding, Li Li, Zhongcheng Wan. Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway. Molecular biology reports. 2023-01-07. PMID:36611117. |
neuronal apoptosis is the main cause for the disabilities and deaths of patients suffered with stroke. |
2023-01-07 |
2023-08-14 |
Not clear |
| Alemiddin Ozdemir, Mustafa Ogden, Bahar Kartal, Asli Fahriye Ceylan, Ulas Yuksel, Bulent Baka. Investigation of therapeutic effects of calcium dobesilate in cerebral hypoxia/ reperfusion injury in rats. Neurological research. 2022-12-22. PMID:36548871. |
cerebral stroke is a serious clinical condition in which oxidative stress, inflammation, necrosis, apoptosis, and autophagy play important roles in its pathogenesis. |
2022-12-22 |
2023-08-14 |
rat |
| Bruno Vergès, Victor Aboyans, Denis Angoulvant, Pierre Boutouyrie, Bertrand Cariou, Fabien Hyafil, Kamel Mohammedi, Pierre Amarenc. Protection against stroke with glucagon-like peptide-1 receptor agonists: a comprehensive review of potential mechanisms. Cardiovascular diabetology. vol 21. issue 1. 2022-11-16. PMID:36380358. |
independently of these peripheral actions, glp-1ras show direct cerebral effects in animal stroke models, such as reduction of infarct volume, apoptosis, oxidative stress, neuroinflammation, excitotoxicity, blood-brain barrier permeability, and increased neurogenesis, neuroplasticity, angiogenesis, and brain perfusion. |
2022-11-16 |
2023-08-14 |
human |
| Jin Sun, Qing Yuan, Lichen Guo, Guangxu Xiao, Tong Zhang, Bing Liang, Rongmei Yao, Yan Zhu, Yue Li, Limin H. Brain Microvascular Endothelial Cell-Derived Exosomes Protect Neurons from Ischemia-Reperfusion Injury in Mice. Pharmaceuticals (Basel, Switzerland). vol 15. issue 10. 2022-10-27. PMID:36297399. |
these results suggest that ec-exo may provide neuroprotection against stroke by promoting synaptic remodeling and inhibiting apoptosis from protecting neurons. |
2022-10-27 |
2023-08-14 |
mouse |
| Yuan Lou, Maoqiang Ma, Yanan Jiang, Haoqun Xu, Zu Gao, Lin Gao, Yuan Wan. Ferroptosis: A new strategy for traditional Chinese medicine treatment of stroke. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 156. 2022-10-13. PMID:36228377. |
the pathological mechanism of stroke is complex and involves various regulated cell death (rcd) modalities such as autophagy, apoptosis and necroptosis. |
2022-10-13 |
2023-08-14 |
human |
| Zhongzhong Jiang, Min Liu, Dezhi Huang, Yang Cai, Yu Zho. Silencing of Long Noncoding RNA GAS5 Blocks Experimental Cerebral Ischemia-Reperfusion Injury by Restraining AQP4 Expression via the miR-1192/STAT5A Axis. Molecular neurobiology. 2022-10-04. PMID:36195691. |
gas5 and stat5a were strongly expressed in stroke patients, and inhibition of gas5 or stat5a in model rats improved neurological function, reduced infarction and neuronal apoptosis, and diminished cerebral water content and astrocyte activation. |
2022-10-04 |
2023-08-14 |
rat |
| Binbin Wang, Lina Ma, Lin Liu, Jin Qin, Tong Li, Kailin Bu, Zhongzhong Li, Honglin Lu, Xiujuan Song, Yanping Cao, Junzhao Cui, Qisong Wang, Si Yuan, Xiaoyun Liu, Li Gu. RIP3/CaMKII/Pyk2 pathway is involved in programmed cell death in a mouse model of brain ischaemic stroke. Neuroscience. 2022-09-26. PMID:36156290. |
neuronal necroptosis and apoptosis are the most important pathways for programmed cell death after brain ischaemic stroke. |
2022-09-26 |
2023-08-14 |
mouse |
| Dong-Hee Choi, In-Ae Choi, Jongmin Le. The Role of DNA Methylation in Stroke Recovery. International journal of molecular sciences. vol 23. issue 18. 2022-09-23. PMID:36142283. |
in this review, we summarize the role of dna methylation in neuroprotection and neuronal recovery after stroke according to the current knowledge regarding the effects of dna methylation on excitotoxicity, oxidative stress, apoptosis, neuroinflammation, and recovery after ischemic stroke. |
2022-09-23 |
2023-08-14 |
Not clear |
| Reem Alkahtan. Molecular mechanisms underlying some major common risk factors of stroke. Heliyon. vol 8. issue 8. 2022-09-05. PMID:36060992. |
abnormalities in the structure of the blood-brain barrier and blood vessels, thrombosis, vasoconstriction, atherosclerosis, reduced cerebral blood flow, neural oxidative stress, inflammation, and apoptosis, impaired synaptic transmission, excitotoxicity, altered expression/activities of many channels and signaling proteins are the most knows mechanisms responsible for stroke induction. |
2022-09-05 |
2023-08-14 |
Not clear |
| Fereshteh Azedi, Shima Tavakol, Arsh Haj Mohamad Ebrahim Ketabforoush, Ghasem Khazaei, Atefeh Bakhtazad, Kazem Mousavizadeh, Mohammad Taghi Joghatae. Modulation of autophagy by melatonin via sirtuins in stroke: From mechanisms to therapies. Life sciences. 2022-08-10. PMID:35948118. |
several mechanisms that have been correlated with stroke are oxidative stress, apoptosis, necrosis and autophagy. |
2022-08-10 |
2023-08-14 |
Not clear |
| Fereshteh Azedi, Shima Tavakol, Arsh Haj Mohamad Ebrahim Ketabforoush, Ghasem Khazaei, Atefeh Bakhtazad, Kazem Mousavizadeh, Mohammad Taghi Joghatae. Modulation of autophagy by melatonin via sirtuins in stroke: From mechanisms to therapies. Life sciences. 2022-08-10. PMID:35948118. |
melatonin and its metabolites adjust various sirtuins pathways related to apoptosis, proliferation, metastases, autophagy and inflammation in case of stroke. |
2022-08-10 |
2023-08-14 |
Not clear |
| Shahein Momenabadi, Abbas Ali Vafaei, Mahdi Zahedi Khorasani, Abedin Vakil. Pre-Ischemic Oxytocin Treatment Alleviated Neuronal Injury via Suppressing NF-κB, MMP-9, and Apoptosis Regulator Proteins in A Mice Model of Stroke. Cell journal. vol 24. issue 6. 2022-07-27. PMID:35892233. |
pre-ischemic oxytocin treatment alleviated neuronal injury via suppressing nf-κb, mmp-9, and apoptosis regulator proteins in a mice model of stroke. |
2022-07-27 |
2023-08-14 |
mouse |