| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Binbin Wang, Lina Ma, Lin Liu, Jin Qin, Tong Li, Kailin Bu, Zhongzhong Li, Honglin Lu, Xiujuan Song, Yanping Cao, Junzhao Cui, Qisong Wang, Si Yuan, Xiaoyun Liu, Li Gu. RIP3/CaMKII/Pyk2 pathway is involved in programmed cell death in a mouse model of brain ischaemic stroke. Neuroscience. 2022-09-26. PMID:36156290. |
neuronal necroptosis and apoptosis are the most important pathways for programmed cell death after brain ischaemic stroke. |
2022-09-26 |
2023-08-14 |
mouse |
| Dong-Hee Choi, In-Ae Choi, Jongmin Le. The Role of DNA Methylation in Stroke Recovery. International journal of molecular sciences. vol 23. issue 18. 2022-09-23. PMID:36142283. |
in this review, we summarize the role of dna methylation in neuroprotection and neuronal recovery after stroke according to the current knowledge regarding the effects of dna methylation on excitotoxicity, oxidative stress, apoptosis, neuroinflammation, and recovery after ischemic stroke. |
2022-09-23 |
2023-08-14 |
Not clear |
| Reem Alkahtan. Molecular mechanisms underlying some major common risk factors of stroke. Heliyon. vol 8. issue 8. 2022-09-05. PMID:36060992. |
abnormalities in the structure of the blood-brain barrier and blood vessels, thrombosis, vasoconstriction, atherosclerosis, reduced cerebral blood flow, neural oxidative stress, inflammation, and apoptosis, impaired synaptic transmission, excitotoxicity, altered expression/activities of many channels and signaling proteins are the most knows mechanisms responsible for stroke induction. |
2022-09-05 |
2023-08-14 |
Not clear |
| Fereshteh Azedi, Shima Tavakol, Arsh Haj Mohamad Ebrahim Ketabforoush, Ghasem Khazaei, Atefeh Bakhtazad, Kazem Mousavizadeh, Mohammad Taghi Joghatae. Modulation of autophagy by melatonin via sirtuins in stroke: From mechanisms to therapies. Life sciences. 2022-08-10. PMID:35948118. |
several mechanisms that have been correlated with stroke are oxidative stress, apoptosis, necrosis and autophagy. |
2022-08-10 |
2023-08-14 |
Not clear |
| Fereshteh Azedi, Shima Tavakol, Arsh Haj Mohamad Ebrahim Ketabforoush, Ghasem Khazaei, Atefeh Bakhtazad, Kazem Mousavizadeh, Mohammad Taghi Joghatae. Modulation of autophagy by melatonin via sirtuins in stroke: From mechanisms to therapies. Life sciences. 2022-08-10. PMID:35948118. |
melatonin and its metabolites adjust various sirtuins pathways related to apoptosis, proliferation, metastases, autophagy and inflammation in case of stroke. |
2022-08-10 |
2023-08-14 |
Not clear |
| Shahein Momenabadi, Abbas Ali Vafaei, Mahdi Zahedi Khorasani, Abedin Vakil. Pre-Ischemic Oxytocin Treatment Alleviated Neuronal Injury via Suppressing NF-κB, MMP-9, and Apoptosis Regulator Proteins in A Mice Model of Stroke. Cell journal. vol 24. issue 6. 2022-07-27. PMID:35892233. |
pre-ischemic oxytocin treatment alleviated neuronal injury via suppressing nf-κb, mmp-9, and apoptosis regulator proteins in a mice model of stroke. |
2022-07-27 |
2023-08-14 |
mouse |
| Afsaneh Asgari Taei, Leila Dargahi, Pariya Khodabakhsh, Mehdi Kadivar, Maryam Farahmandfa. Hippocampal neuroprotection mediated by secretome of human mesenchymal stem cells against experimental stroke. CNS neuroscience & therapeutics. 2022-06-18. PMID:35715988. |
here, we explored the effects of secretome or conditioned medium (cm) derived from human embryonic stem cell-derived mscs (hesc-mscs) on hippocampal neurogenesis, inflammation, and apoptosis in experimental stroke. |
2022-06-18 |
2023-08-14 |
human |
| Chenyang Gu, Qiankun Zhang, Yajing Li, Rong Li, Jia Feng, Wanghao Chen, Waqas Ahmed, Ismatullah Soufiany, Shiying Huang, Jun Long, Lukui Che. The PI3K/AKT Pathway-The Potential Key Mechanisms of Traditional Chinese Medicine for Stroke. Frontiers in medicine. vol 9. 2022-06-17. PMID:35712089. |
the phosphatidylinositol 3 kinase (pi3k)/protein kinase b (akt) pathway is important for regulation of cell migration, proliferation, differentiation, and apoptosis, and plays a vital role in vascularization and oxidative stress in stroke. |
2022-06-17 |
2023-08-14 |
Not clear |
| Chenyang Gu, Qiankun Zhang, Yajing Li, Rong Li, Jia Feng, Wanghao Chen, Waqas Ahmed, Ismatullah Soufiany, Shiying Huang, Jun Long, Lukui Che. The PI3K/AKT Pathway-The Potential Key Mechanisms of Traditional Chinese Medicine for Stroke. Frontiers in medicine. vol 9. 2022-06-17. PMID:35712089. |
tcm treatment significantly reduces neuronal damage, inhibits cell apoptosis, and delays progression of stroke via various pi3k/akt-mediated downstream pathways. |
2022-06-17 |
2023-08-14 |
Not clear |
| Moez Eid, Valentina Dzreyan, Svetlana Demyanenk. Sirtuins 1 and 2 in the Acute Period After Photothrombotic Stroke: Expression, Localization and Involvement in Apoptosis. Frontiers in physiology. vol 13. 2022-05-16. PMID:35574497. |
sirtuins 1 and 2 in the acute period after photothrombotic stroke: expression, localization and involvement in apoptosis. |
2022-05-16 |
2023-08-13 |
Not clear |
| Xiuping Chen, Xin Zhan. Effect of prior exposure to enriched environment on cellular apoptosis after experimental stroke. Molecular biology reports. 2022-05-04. PMID:35507114. |
effect of prior exposure to enriched environment on cellular apoptosis after experimental stroke. |
2022-05-04 |
2023-08-13 |
rat |
| Xiao-Ling Fang, Shao-Yun Ding, Xiao-Zheng Du, Jin-Hai Wang, Xing-Lan L. Ferroptosis-A Novel Mechanism With Multifaceted Actions on Stroke. Frontiers in neurology. vol 13. 2022-04-28. PMID:35481263. |
as a neurological disease with high morbidity, disability, and mortality, the pathological mechanism underlying stroke involves complex processes such as neuroinflammation, oxidative stress, apoptosis, autophagy, and excitotoxicity; but the related research on these molecular mechanisms has not been effectively applied in clinical practice. |
2022-04-28 |
2023-08-13 |
Not clear |
| Ulkan Kilic, Birsen Elibol, Ahmet Burak Caglayan, Mustafa Caglar Beker, Merve Beker, Burcugul Altug-Tasa, Omer Uysal, Bayram Yilmaz, Ertugrul Kili. Delayed Therapeutic Administration of Melatonin Enhances Neuronal Survival Through AKT and MAPK Signaling Pathways Following Focal Brain Ischemia in Mice. Journal of molecular neuroscience : MN. 2022-03-21. PMID:35307786. |
therefore, in the present study, the coordination of ipsilateral and contralateral hemispheres to evaluate delayed post-acute effect of melatonin was examined on recovery of the cell survival and apoptosis after stroke. |
2022-03-21 |
2023-08-13 |
mouse |
| Ulkan Kilic, Birsen Elibol, Ahmet Burak Caglayan, Mustafa Caglar Beker, Merve Beker, Burcugul Altug-Tasa, Omer Uysal, Bayram Yilmaz, Ertugrul Kili. Delayed Therapeutic Administration of Melatonin Enhances Neuronal Survival Through AKT and MAPK Signaling Pathways Following Focal Brain Ischemia in Mice. Journal of molecular neuroscience : MN. 2022-03-21. PMID:35307786. |
this neurological recovery was also reflected by high level of neun positive cells and low level of tunel-positive cells suggesting enhanced neuronal survival and reduced apoptosis at the fifty-fifth day of stroke. |
2022-03-21 |
2023-08-13 |
mouse |
| Lin-Yan Huang, Jin-Xiu Song, Heng Cai, Pei-Pei Wang, Qi-Long Yin, Yi-De Zhang, Jie Chen, Ming Li, Jia-Jia Song, Yan-Ling Wang, Lan Luo, Wan Wang, Su-Hua Q. Healthy Serum-Derived Exosomes Improve Neurological Outcomes and Protect Blood-Brain Barrier by Inhibiting Endothelial Cell Apoptosis and Reversing Autophagy-Mediated Tight Junction Protein Reduction in Rat Stroke Model. Frontiers in cellular neuroscience. vol 16. 2022-03-21. PMID:35308117. |
healthy serum-derived exosomes improve neurological outcomes and protect blood-brain barrier by inhibiting endothelial cell apoptosis and reversing autophagy-mediated tight junction protein reduction in rat stroke model. |
2022-03-21 |
2023-08-13 |
rat |
| Yamei Li, Bo Peng, Yi Li, Airu Huang, Yinian Peng, Qian Yu, Yufeng L. MiR-203a-3p/153-3p improves cognitive impairments induced by ischemia/reperfusion via blockade of SRC-mediated MAPK signaling pathway in ischemic stroke. Chemico-biological interactions. 2022-03-20. PMID:35305977. |
thus, mir-203a-3p and mir-153-3p confers neuroprotective effects against ischemic stroke via attenuation of apoptosis, oxidative stress and inflammatory pathways through inhibiting src-dependent mapk signaling pathway in vivo and in vitro, suggesting new therapeutic targets for the prevention and treatment of stroke. |
2022-03-20 |
2023-08-13 |
rat |
| Harpreet Kaur, Deepaneeta Sarmah, Pabbala Veeresh, Aishika Datta, Kiran Kalia, Anupom Borah, Dileep R Yavagal, Pallab Bhattachary. Correction to Endovascular Stem Cell Therapy Post Stroke Rescues Neurons from Endoplasmic Reticulum Stress-Induced Apoptosis by Modulating Brain-Derived Neurotrophic Factor/Tropomyosin Receptor Kinase B Signaling. ACS chemical neuroscience. 2022-02-25. PMID:35213146. |
correction to endovascular stem cell therapy post stroke rescues neurons from endoplasmic reticulum stress-induced apoptosis by modulating brain-derived neurotrophic factor/tropomyosin receptor kinase b signaling. |
2022-02-25 |
2023-08-13 |
Not clear |
| Balu Joshi, Devendra Singh, Himika Wasan, Uma Sharma, K H Reet. Tideglusib Ameliorates Ischemia/Reperfusion Damage by Inhibiting GSK-3β and Apoptosis in Rat Model of Ischemic Stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 31. issue 4. 2022-02-13. PMID:35152130. |
glycogen synthase kinase-3β (gsk-3β), a serine/threonine protein kinase, gets activated and worsen stroke outcome after ischemia/reperfusion (i/r) injury by inducing inflammation and apoptosis. |
2022-02-13 |
2023-08-13 |
rat |
| Taotao Lu, Huihong Li, Yangjie Zhou, Wei Wei, Linlin Ding, Zengtu Zhan, Weilin Liu, Jing Tao, Xiehua Xu. Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway. Journal of neuroinflammation. vol 19. issue 1. 2022-02-08. PMID:35130910. |
neuroinflammation and apoptosis are involved in the pathogenesis of ischaemic stroke. |
2022-02-08 |
2023-08-13 |
Not clear |
| Zhongcheng Wang, Yaxin Su, Lei Zhang, Ting Lan, Li Li, Suhua Q. GSK-126 Protects CA1 Neurons from H3K27me3-Mediated Apoptosis in Cerebral Ischemia. Molecular neurobiology. 2022-01-29. PMID:35091962. |
the administration of gsk-126 to rat brains decreased the levels of h3k27me3 in the hippocampus and reduced neuronal apoptosis after experimental stroke. |
2022-01-29 |
2023-08-13 |
rat |