| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L S Kegeles, D C Shungu, S Anjilvel, S Chan, S P Ellis, E Xanthopoulos, D Malaspina, J M Gorman, J J Mann, M Laruelle, C A Kaufman. Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies. Psychiatry research. vol 98. issue 3. 2000-07-19. PMID:10821999. |
hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies. |
2000-07-19 |
2023-08-12 |
human |
| L S Kegeles, D C Shungu, S Anjilvel, S Chan, S P Ellis, E Xanthopoulos, D Malaspina, J M Gorman, J J Mann, M Laruelle, C A Kaufman. Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies. Psychiatry research. vol 98. issue 3. 2000-07-19. PMID:10821999. |
the hippocampus is a site of previously reported structural and functional abnormalities in schizophrenia. |
2000-07-19 |
2023-08-12 |
human |
| L S Kegeles, D C Shungu, S Anjilvel, S Chan, S P Ellis, E Xanthopoulos, D Malaspina, J M Gorman, J J Mann, M Laruelle, C A Kaufman. Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies. Psychiatry research. vol 98. issue 3. 2000-07-19. PMID:10821999. |
measurements were obtained of the medial temporal lobe, centered on the hippocampus, in 10 male patients with schizophrenia (3 neuroleptic-medicated and 7 medication-free), and 10 matched normal volunteers. |
2000-07-19 |
2023-08-12 |
human |
| X M Gao, K Sakai, R C Roberts, R R Conley, B Dean, C A Tamming. Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. The American journal of psychiatry. vol 157. issue 7. 2000-07-19. PMID:10873924. |
ionotropic glutamate receptors and expression of n-methyl-d-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. |
2000-07-19 |
2023-08-12 |
human |
| X M Gao, K Sakai, R C Roberts, R R Conley, B Dean, C A Tamming. Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. The American journal of psychiatry. vol 157. issue 7. 2000-07-19. PMID:10873924. |
multiple quantifiable biologic abnormalities have been localized to the hippocampus in schizophrenia. |
2000-07-19 |
2023-08-12 |
human |
| X M Gao, K Sakai, R C Roberts, R R Conley, B Dean, C A Tamming. Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. The American journal of psychiatry. vol 157. issue 7. 2000-07-19. PMID:10873924. |
the authors tested the hypothesis that glutamatergic transmission within and efferent from hippocampus is altered in schizophrenia. |
2000-07-19 |
2023-08-12 |
human |
| M P Laakso, O Vaurio, L Savolainen, E Repo, H Soininen, H J Aronen, J Tiihone. A volumetric MRI study of the hippocampus in type 1 and 2 alcoholism. Behavioural brain research. vol 109. issue 2. 2000-06-21. PMID:10762687. |
particularly in studies on schizophrenia and mood disorders, findings regarding the hippocampal involvement have been most controversial. |
2000-06-21 |
2023-08-12 |
human |
| Y Hirayasu, M E Shenton, D F Salisbury, R W McCarle. Hippocampal and superior temporal gyrus volume in first-episode schizophrenia. Archives of general psychiatry. vol 57. issue 6. 2000-06-07. PMID:10839342. |
hippocampal and superior temporal gyrus volume in first-episode schizophrenia. |
2000-06-07 |
2023-08-12 |
Not clear |
| J Behr, T Gloveli, D Schmitz, U Heineman. Dopamine depresses polysynaptic inhibition in rat subicular neurons. Brain research. vol 861. issue 1. 2000-06-06. PMID:10751576. |
schizophrenia is considered to be associated with a hyperfunction of the dopaminergic system and with abnormalities in hippocampal information processing. |
2000-06-06 |
2023-08-12 |
rat |
| M Cyr, O Ghribi, T Di Paol. Regional and selective effects of oestradiol and progesterone on NMDA and AMPA receptors in the rat brain. Journal of neuroendocrinology. vol 12. issue 5. 2000-05-31. PMID:10792584. |
the effect of oestradiol in the hippocampus confirmed in the present study and our novel findings in the frontal cortex, striatum and nucleus accumbens may have functional significance for schizophrenia and neurodegenerative diseases. |
2000-05-31 |
2023-08-12 |
rat |
| D Copolov, D Velakoulis, P McGorry, Carina Mallard, A Yung, S Rees, G Jackson, A Rehn, W Brewer, C Panteli. Neurobiological findings in early phase schizophrenia. Brain research. Brain research reviews. vol 31. issue 2-3. 2000-05-17. PMID:10719144. |
this paper summarises the available information on mri-determined hippocampal morphometry in first-episode patients as an illustration of the value and interpretation of findings in the neurobiology of early phase schizophrenia. |
2000-05-17 |
2023-08-12 |
human |
| J H Meador-Woodruff, D J Heal. Glutamate receptor expression in schizophrenic brain. Brain research. Brain research reviews. vol 31. issue 2-3. 2000-05-17. PMID:10719155. |
the expression of the glutamate receptors has been determined at multiple levels of gene expression in postmortem brain samples from schizophrenics and controls; while results have not been entirely consistent from study to study, several generalizations have emerged from this literature: (1) the ampa receptor is abnormally decreased in expression in the schizophrenic hippocampus, involving decreased levels of subunit transcripts and protein levels, as well as binding sites, (2) similar changes are seen for kainate receptor expression in the hippocampus, and (3) the obligate nmda receptor subunit, nmdar1, may be abnormally expressed in some cortical regions in schizophrenia. |
2000-05-17 |
2023-08-12 |
Not clear |
| A A Grac. Gating of information flow within the limbic system and the pathophysiology of schizophrenia. Brain research. Brain research reviews. vol 31. issue 2-3. 2000-05-17. PMID:10719160. |
therefore, schizophrenia is proposed to be a developmentally-related disorder, in which disruption of the hippocampal influence over the limbic system during ontogeny results in a pathological alteration of corticoaccumbens interactions in the adult organism. |
2000-05-17 |
2023-08-12 |
rat |
| K Mizukami, M Sasaki, M Ishikawa, M Iwakiri, S Hidaka, H Shiraishi, S Iritan. Immunohistochemical localization of gamma-aminobutyric acid(B) receptor in the hippocampus of subjects with schizophrenia. Neuroscience letters. vol 283. issue 2. 2000-05-12. PMID:10739885. |
immunohistochemical localization of gamma-aminobutyric acid(b) receptor in the hippocampus of subjects with schizophrenia. |
2000-05-12 |
2023-08-12 |
human |
| K Mizukami, M Sasaki, M Ishikawa, M Iwakiri, S Hidaka, H Shiraishi, S Iritan. Immunohistochemical localization of gamma-aminobutyric acid(B) receptor in the hippocampus of subjects with schizophrenia. Neuroscience letters. vol 283. issue 2. 2000-05-12. PMID:10739885. |
in order to further elucidate the alterations of this system in schizophrenia, we employed immunohistochemical techniques and examined the expression and anatomical distribution of the gaba(b) receptor in the hippocampus of five subjects with schizophrenia and three age-matched controls. |
2000-05-12 |
2023-08-12 |
human |
| S J Wood, D Velakoulis, C Panteli. Volume of parahippocampal gyrus and hippocampus in schizophrenia. The British journal of psychiatry : the journal of mental science. vol 175. 2000-05-12. PMID:10789308. |
volume of parahippocampal gyrus and hippocampus in schizophrenia. |
2000-05-12 |
2023-08-12 |
Not clear |
| S L Eastwood, N J Cairns, P J Harriso. Synaptophysin gene expression in schizophrenia. Investigation of synaptic pathology in the cerebral cortex. The British journal of psychiatry : the journal of mental science. vol 176. 2000-05-04. PMID:10755070. |
decreased expression of proteins such as synaptophysin in the hippocampus and prefrontal cortex in schizophrenia is suggestive of synaptic pathology. |
2000-05-04 |
2023-08-12 |
Not clear |
| A Becker, G Grecksc. Social memory is impaired in neonatally ibotenic acid lesioned rats. Behavioural brain research. vol 109. issue 1. 2000-05-03. PMID:10699665. |
postnatal lesion with ibotenic acid in the ventral hippocampus produces several behavioural effects that resemble the symptoms of schizophrenia. |
2000-05-03 |
2023-08-12 |
rat |
| R F Deicken, C Johnson, M Pegue. Proton magnetic resonance spectroscopy of the human brain in schizophrenia. Reviews in the neurosciences. vol 11. issue 2-3. 2000-04-11. PMID:10718151. |
to date, the most consistently replicated findings in schizophrenia are reduced naa measures in the hippocampal regions. |
2000-04-11 |
2023-08-12 |
human |
| D Cotter, S Wilson, E Roberts, R Kerwin, I P Everal. Increased dendritic MAP2 expression in the hippocampus in schizophrenia. Schizophrenia research. vol 41. issue 2. 2000-03-31. PMID:10708340. |
increased dendritic map2 expression in the hippocampus in schizophrenia. |
2000-03-31 |
2023-08-12 |
human |