| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Velakoulis, G W Stuart, S J Wood, D J Smith, W J Brewer, P Desmond, B Singh, D Copolov, C Panteli. Selective bilateral hippocampal volume loss in chronic schizophrenia. Biological psychiatry. vol 50. issue 7. 2001-12-04. PMID:11600106. |
the hippocampus is implicated in the pathophysiology of schizophrenia; however, volumetric changes are subtle and have limited diagnostic specificity. |
2001-12-04 |
2023-08-12 |
Not clear |
| D Velakoulis, G W Stuart, S J Wood, D J Smith, W J Brewer, P Desmond, B Singh, D Copolov, C Panteli. Selective bilateral hippocampal volume loss in chronic schizophrenia. Biological psychiatry. vol 50. issue 7. 2001-12-04. PMID:11600106. |
it is possible that the shape of the hippocampus may be more characteristic of schizophrenia. |
2001-12-04 |
2023-08-12 |
Not clear |
| N R Swerdlow, N Halim, F M Hanlon, A Platten, P P Auerbac. Lesion size and amphetamine hyperlocomotion after neonatal ventral hippocampal lesions: more is less. Brain research bulletin. vol 55. issue 1. 2001-10-11. PMID:11427340. |
neonatal hippocampal lesions in rats produce behavioral and neurochemical abnormalities post-puberty that are used in animal models for developmentally linked pathology in schizophrenia. |
2001-10-11 |
2023-08-12 |
rat |
| L Wang, S C Joshi, M I Miller, J G Csernansk. Statistical analysis of hippocampal asymmetry in schizophrenia. NeuroImage. vol 14. issue 3. 2001-10-11. PMID:11506528. |
statistical analysis of hippocampal asymmetry in schizophrenia. |
2001-10-11 |
2023-08-12 |
human |
| L Wang, S C Joshi, M I Miller, J G Csernansk. Statistical analysis of hippocampal asymmetry in schizophrenia. NeuroImage. vol 14. issue 3. 2001-10-11. PMID:11506528. |
we observed that the right hippocampus was wider along its lateral side in both schizophrenia and control subjects. |
2001-10-11 |
2023-08-12 |
human |
| L Wang, S C Joshi, M I Miller, J G Csernansk. Statistical analysis of hippocampal asymmetry in schizophrenia. NeuroImage. vol 14. issue 3. 2001-10-11. PMID:11506528. |
also, while patterns of hippocampal asymmetry were generally similar in the schizophrenia and control groups, a principal component analysis based on left-right asymmetry vector fields detected a statistically significant difference between the two groups, specifically related to the subiculum. |
2001-10-11 |
2023-08-12 |
human |
| B K Lipska, Z Z Khaing, C S Weickert, D R Weinberge. BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. The European journal of neuroscience. vol 14. issue 1. 2001-09-27. PMID:11488957. |
to clarify the effects of antipsychotic drugs used in the therapy of schizophrenia on bdnf mrna, we studied its expression in rats treated with clozapine and haloperidol and in rats with neonatal lesions of the ventral hippocampus, used as an animal model of schizophrenia. |
2001-09-27 |
2023-08-12 |
rat |
| A P Weiss, S Hecker. Neuroimaging of declarative memory in schizophrenia. Scandinavian journal of psychology. vol 42. issue 3. 2001-09-13. PMID:11501738. |
memory impairment in schizophrenia appears to involve abnormal connectivity between the prefrontal cortex and three regions important in normal learning and memory: the hippocampus, thalamus, and cerebellum. |
2001-09-13 |
2023-08-12 |
Not clear |
| H Matsumoto, A Simmons, S Williams, R Pipe, R Murray, S Frango. Structural magnetic imaging of the hippocampus in early onset schizophrenia. Biological psychiatry. vol 49. issue 10. 2001-08-23. PMID:11343679. |
structural magnetic imaging of the hippocampus in early onset schizophrenia. |
2001-08-23 |
2023-08-12 |
Not clear |
| H Matsumoto, A Simmons, S Williams, R Pipe, R Murray, S Frango. Structural magnetic imaging of the hippocampus in early onset schizophrenia. Biological psychiatry. vol 49. issue 10. 2001-08-23. PMID:11343679. |
previous literature suggests that hippocampal volume reductions in schizophrenia may occur either during adolescence or at the point of transition to overt psychosis. |
2001-08-23 |
2023-08-12 |
Not clear |
| M J Webster, C Shannon Weickert, M M Herman, T M Hyde, J E Kleinma. Synaptophysin and GAP-43 mRNA levels in the hippocampus of subjects with schizophrenia. Schizophrenia research. vol 49. issue 1-2. 2001-08-09. PMID:11343868. |
synaptophysin and gap-43 mrna levels in the hippocampus of subjects with schizophrenia. |
2001-08-09 |
2023-08-12 |
human |
| M P Laakso, J Tiihonen, E Syvälahti, H Vilkman, A Laakso, B Alakare, V Räkköläinen, R K Salokangas, E Koivisto, J Hietal. A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naïve schizophrenia. Schizophrenia research. vol 50. issue 1-2. 2001-08-09. PMID:11378309. |
a morphometric mri study of the hippocampus in first-episode, neuroleptic-naïve schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |
| M P Laakso, J Tiihonen, E Syvälahti, H Vilkman, A Laakso, B Alakare, V Räkköläinen, R K Salokangas, E Koivisto, J Hietal. A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naïve schizophrenia. Schizophrenia research. vol 50. issue 1-2. 2001-08-09. PMID:11378309. |
magnetic resonance imaging (mri) studies have frequently, although not unambiguously, reported hippocampal volume deficit in schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |
| M P Laakso, J Tiihonen, E Syvälahti, H Vilkman, A Laakso, B Alakare, V Räkköläinen, R K Salokangas, E Koivisto, J Hietal. A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naïve schizophrenia. Schizophrenia research. vol 50. issue 1-2. 2001-08-09. PMID:11378309. |
in this study two-dimensional mri-based topographic brain mapping was used to study the possibility of regional changes in the hippocampus of 22 controls and 18 patients with first-episode, neuroleptic-naïve schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |
| M P Laakso, J Tiihonen, E Syvälahti, H Vilkman, A Laakso, B Alakare, V Räkköläinen, R K Salokangas, E Koivisto, J Hietal. A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naïve schizophrenia. Schizophrenia research. vol 50. issue 1-2. 2001-08-09. PMID:11378309. |
compared to controls, there were no significant differences between hippocampal volumes, regional volumes, or length of the hippocampus in the patients with schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |
| M P Laakso, J Tiihonen, E Syvälahti, H Vilkman, A Laakso, B Alakare, V Räkköläinen, R K Salokangas, E Koivisto, J Hietal. A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naïve schizophrenia. Schizophrenia research. vol 50. issue 1-2. 2001-08-09. PMID:11378309. |
these data are at odds with the previous reports on hippocampal volume loss in first-episode schizophrenia, and with the hypothesis of regionally specific hippocampal volume deficit in schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |
| F M Benes, S Berrett. GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 1. 2001-08-02. PMID:11377916. |
by using "partial" modeling, changes in the gaba system remarkably similar to those seen in schizophrenia and bipolar disorder have been induced in rat hippocampus. |
2001-08-02 |
2023-08-12 |
human |
| R S Devon, S Anderson, P W Teague, W J Muir, V Murray, A J Pelosi, D H Blackwood, D J Porteou. The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia. Molecular psychiatry. vol 6. issue 3. 2001-07-26. PMID:11326300. |
(1-3) electrophysiological studies in grm subtype 5 knockout mice reveal, in one study, a sensorimotor gating deficit characteristic of schizophrenia and in another, a key rôle for this gene in the modulation of hippocampal nmda-dependent synaptic plasticity. |
2001-07-26 |
2023-08-12 |
mouse |
| S B Floresco, C L Todd, A A Grac. Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 13. 2001-07-26. PMID:11425919. |
as a result, dysfunctions in hippocampal circuitries may contribute to the hyperexcitable state of the da system that is present in schizophrenia. |
2001-07-26 |
2023-08-12 |
Not clear |
| T Bast, W N Zhang, C Heidbreder, J Feldo. Hyperactivity and disruption of prepulse inhibition induced by N-methyl-D-aspartate stimulation of the ventral hippocampus and the effects of pretreatment with haloperidol and clozapine. Neuroscience. vol 103. issue 2. 2001-06-14. PMID:11246148. |
the present finding that both clozapine and haloperidol failed to antagonize the disruption of prepulse inhibition induced by n-methyl-d-aspartate stimulation of the ventral hippocampus is discussed with respect to our previous contrary finding concerning the ameliorative effect of clozapine and with respect to the disruption of prepulse inhibition in rats being considered as a model of sensorimotor gating deficits in schizophrenia. |
2001-06-14 |
2023-08-12 |
rat |