| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Freedman, C E Adams, S Leonar. The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. Journal of chemical neuroanatomy. vol 20. issue 3-4. 2001-05-24. PMID:11207427. |
the alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. |
2001-05-24 |
2023-08-12 |
human |
| R Freedman, C E Adams, S Leonar. The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. Journal of chemical neuroanatomy. vol 20. issue 3-4. 2001-05-24. PMID:11207427. |
convergent information indicates that interneurons in the hippocampus and other forebrain structures are decreased in number and function in subjects with schizophrenia. |
2001-05-24 |
2023-08-12 |
human |
| C S Weickert, M J Webster, T M Hyde, M M Herman, S E Bachus, G Bali, D R Weinberger, J E Kleinma. Reduced GAP-43 mRNA in dorsolateral prefrontal cortex of patients with schizophrenia. Cerebral cortex (New York, N.Y. : 1991). vol 11. issue 2. 2001-05-17. PMID:11208668. |
using the rnase protection assay (rpa), we found a significant reduction in gap-43 mrna in the dlpfc, but not in the hippocampus, of patients with schizophrenia. |
2001-05-17 |
2023-08-12 |
human |
| M Aso, M Suzuki, Y Kawasaki, M Matsui, H Hagino, K Kurokawa, H Seto, M Kurach. Sylvian fissure and medial temporal lobe structures in patients with schizophrenia: a magnetic resonance imaging study. Psychiatry and clinical neurosciences. vol 55. issue 1. 2001-05-17. PMID:11235858. |
the amygdala, hippocampus, and parahippocampal gyrus), sylvian fissure, and inferior horn of the lateral ventricle relative to the cerebral hemisphere were measured in 24 patients with schizophrenia and 23 normal controls using magnetic resonance imaging. |
2001-05-17 |
2023-08-12 |
Not clear |
| A R Sanders, P V Gejma. Major corrections are indicated for 'Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia'. Molecular psychiatry. vol 6. issue 1. 2001-05-10. PMID:11244479. |
major corrections are indicated for 'comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia'. |
2001-05-10 |
2023-08-12 |
Not clear |
| S Berretta, D W Munno, F M Bene. Amygdalar activation alters the hippocampal GABA system: "partial" modelling for postmortem changes in schizophrenia. The Journal of comparative neurology. vol 431. issue 2. 2001-04-26. PMID:11169995. |
amygdalar activation alters the hippocampal gaba system: "partial" modelling for postmortem changes in schizophrenia. |
2001-04-26 |
2023-08-12 |
rat |
| S Berretta, D W Munno, F M Bene. Amygdalar activation alters the hippocampal GABA system: "partial" modelling for postmortem changes in schizophrenia. The Journal of comparative neurology. vol 431. issue 2. 2001-04-26. PMID:11169995. |
abnormalities in amygdala and hippocampus have been shown to coexist in schizophrenia (sz). |
2001-04-26 |
2023-08-12 |
rat |
| S Berretta, D W Munno, F M Bene. Amygdalar activation alters the hippocampal GABA system: "partial" modelling for postmortem changes in schizophrenia. The Journal of comparative neurology. vol 431. issue 2. 2001-04-26. PMID:11169995. |
the amygdala sends important inputs to the hippocampus and is also believed to have a defective gaba system in schizophrenia. |
2001-04-26 |
2023-08-12 |
rat |
| C D Stine, W Lu, M E Wol. Expression of AMPA receptor flip and flop mRNAs in the nucleus accumbens and prefrontal cortex after neonatal ventral hippocampal lesions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 3. 2001-04-19. PMID:11166516. |
the present study examined alpha-amino-3-hydroxy-5-methylisoxazole- 4-priopionate (ampa) receptor expression in the prefrontal cortex (pfc) and nucleus accumbens (nac) using a rat model of schizophrenia in which excitotoxic lesions of ventral hippocampus (vh) on postnatal day (pd) 7 lead to the postpubertal emergence of behavioral abnormalities that resemble schizophrenic symptoms. |
2001-04-19 |
2023-08-12 |
rat |
| K Kato, T Shishido, M Ono, K Shishido, M Kobayashi, S Niw. Glycine reduces novelty- and methamphetamine-induced locomotor activity in neonatal ventral hippocampal damaged rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 3. 2001-04-19. PMID:11166522. |
the use of neonatal ventral hippocampal nvh lesioned rats is well established in animal models of schizophrenia. |
2001-04-19 |
2023-08-12 |
rat |
| D Velakoulis, S J Wood, P D McGorry, C Panteli. Evidence for progression of brain structural abnormalities in schizophrenia: beyond the neurodevelopmental model. The Australian and New Zealand journal of psychiatry. vol 34 Suppl. 2001-03-15. PMID:11129295. |
the purpose of this paper is to present published findings concerning the nature, timing and course of these putative disturbances of hippocampal function and the pathophysiological mechanisms involved, and to explore whether schizophrenia is a disorder of neurodevelopment, neurodegeneration or a combination of both processes. |
2001-03-15 |
2023-08-12 |
Not clear |
| T Ohnuma, S Tessler, H Arai, R L Faull, P J McKenna, P C Emso. Gene expression of metabotropic glutamate receptor 5 and excitatory amino acid transporter 2 in the schizophrenic hippocampus. Brain research. Molecular brain research. vol 85. issue 1-2. 2001-03-08. PMID:11146103. |
a disturbance in glutamatergic transmission has been suggested to contribute to the pathophysiology of schizophrenia and recent studies on ionotropic glutamate receptors are consistent with altered glutamatergic function in the hippocampus of schizophrenics. |
2001-03-08 |
2023-08-12 |
human |
| T Ohnuma, S Tessler, H Arai, R L Faull, P J McKenna, P C Emso. Gene expression of metabotropic glutamate receptor 5 and excitatory amino acid transporter 2 in the schizophrenic hippocampus. Brain research. Molecular brain research. vol 85. issue 1-2. 2001-03-08. PMID:11146103. |
the results suggest that a disturbance of glutamatergic neurotransmission in schizophrenia was not apparent using these indices in the hippocampus, but 'hypo-glutamatergic' neurotransmission may be present in the schizophrenic parahippocampal gyrus. |
2001-03-08 |
2023-08-12 |
human |
| E Scarr, D L Copolov, B Dea. A proposed pathological model in the hippocampus of subjects with schizophrenia. Clinical and experimental pharmacology & physiology. vol 28. issue 1-2. 2001-03-08. PMID:11153541. |
a proposed pathological model in the hippocampus of subjects with schizophrenia. |
2001-03-08 |
2023-08-12 |
human |
| D Dowlatshahi, G MacQueen, J F Wang, B Chen, L T Youn. Increased hippocampal supragranular Timm staining in subjects with bipolar disorder. Neuroreport. vol 11. issue 17. 2001-03-01. PMID:11117489. |
frozen postmortem hippocampal sections from subjects with major depression, bipolar disorder, schizophrenia and non-psychiatric controls were stained using the neo-timm procedure, which selectively stains mossy fibers. |
2001-03-01 |
2023-08-12 |
human |
| T Ohnuma, H Kato, H Arai, R L Faull, P J McKenna, P C Emso. Gene expression of PSD95 in prefrontal cortex and hippocampus in schizophrenia. Neuroreport. vol 11. issue 14. 2001-02-22. PMID:11043537. |
gene expression of psd95 in prefrontal cortex and hippocampus in schizophrenia. |
2001-02-22 |
2023-08-12 |
Not clear |
| K Blennow, N Bogdanovic, M Heilig, B Grenfeldt, I Karlsson, P Davidsso. Reduction of the synaptic protein rab3a in the thalamus and connecting brain regions in post-mortem schizophrenic brains. Journal of neural transmission (Vienna, Austria : 1996). vol 107. issue 8-9. 2001-02-15. PMID:11041284. |
reduced rab3a protein levels were found schizophrenia also in the frontal cortex, hippocampus, gyrus cinguli, and parietal cortex, while no significant differences were found in the temporal cortex, or in cerebellum. |
2001-02-15 |
2023-08-12 |
human |
| S H Fatemi, J A Earle, T McMenom. Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression. Molecular psychiatry. vol 5. issue 6. 2001-02-15. PMID:11126396. |
we present new immunocytochemical evidence showing reductions in reelin expression in hippocampus of subjects with schizophrenia, bipolar disorder and major depression and confirm recent reports documenting a similar deficit involving reelin expression in brains of subjects with schizophrenia and bipolar disorder. |
2001-02-15 |
2023-08-12 |
human |
| D J Walder, E F Walker, R J Lewin. Cognitive functioning, cortisol release, and symptom severity in patients with schizophrenia. Biological psychiatry. vol 48. issue 12. 2001-02-08. PMID:11137052. |
there is substantial evidence of dysregulation of cortisol secretion, hippocampal abnormalities, and memory deficits in schizophrenia and other psychotic disorders. |
2001-02-08 |
2023-08-12 |
Not clear |
| M P Vawte. Dysregulation of the neural cell adhesion molecule and neuropsychiatric disorders. European journal of pharmacology. vol 405. issue 1-3. 2001-01-08. PMID:11033343. |
potential test of the n-cam dysregulation hypothesis of neuropsychiatric disorder is whether ongoing dysregulation of n-cam would cause cognitive impairments, increased lateral ventricle volume, and decreased hippocampal volume observed in schizophrenia and to a lesser extent in bipolar disorder. |
2001-01-08 |
2023-08-12 |
Not clear |