| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Blennow, N Bogdanovic, C G Gottfries, P Davidsso. The growth-associated protein GAP-43 is increased in the hippocampus and in the gyrus cinguli in schizophrenia. Journal of molecular neuroscience : MN. vol 13. issue 1-2. 2000-03-21. PMID:10691297. |
the growth-associated protein gap-43 is increased in the hippocampus and in the gyrus cinguli in schizophrenia. |
2000-03-21 |
2023-08-12 |
Not clear |
| P F Edgar, J E Douglas, G J Cooper, B Dean, R Kydd, R L Faul. Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia. Molecular psychiatry. vol 5. issue 1. 2000-03-17. PMID:10673773. |
comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia. |
2000-03-17 |
2023-08-12 |
Not clear |
| P F Edgar, J E Douglas, G J Cooper, B Dean, R Kydd, R L Faul. Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia. Molecular psychiatry. vol 5. issue 1. 2000-03-17. PMID:10673773. |
these results indicate that antioxidant defence is altered in the schizophrenic hippocampus and suggest that segregation distortion, of schizophrenia susceptibility genes, may be a possible causative factor in the high incidence of schizophrenia. |
2000-03-17 |
2023-08-12 |
Not clear |
| M C Waldo, L E Adler, S Leonard, A Olincy, R G Ross, J G Harris, R Freedma. Familial transmission of risk factors in the first-degree relatives of schizophrenic people. Biological psychiatry. vol 47. issue 3. 2000-03-17. PMID:10682220. |
although such research is far from complete, a heuristic model combining a sensory gating deficit, decreased hippocampal neuron capacity, and increased dopaminergic neurotransmission is consonant with current understanding of the neuropsychology of schizophrenia. |
2000-03-17 |
2023-08-12 |
Not clear |
| A Kelemen, G Székely, G Geri. Elastic model-based segmentation of 3-D neuroradiological data sets. IEEE transactions on medical imaging. vol 18. issue 10. 2000-01-28. PMID:10628943. |
the technique has been applied to automatically segment left and right hippocampus, thalamus, putamen, and globus pallidus from volumetric magnetic resonance scans taken from schizophrenia studies. |
2000-01-28 |
2023-08-12 |
Not clear |
| D W Zaide. Regional differentiation of neuron morphology in human left and right hippocampus: comparing normal to schizophrenia. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 34. issue 3. 2000-01-27. PMID:10610043. |
regional differentiation of neuron morphology in human left and right hippocampus: comparing normal to schizophrenia. |
2000-01-27 |
2023-08-12 |
human |
| K Razi, K P Greene, M Sakuma, S Ge, M Kushner, L E DeLis. Reduction of the parahippocampal gyrus and the hippocampus in patients with chronic schizophrenia. The British journal of psychiatry : the journal of mental science. vol 174. 2000-01-24. PMID:10616629. |
reduction of the parahippocampal gyrus and the hippocampus in patients with chronic schizophrenia. |
2000-01-24 |
2023-08-12 |
Not clear |
| T A Bayer, R Buslei, L Havas, P Falka. Evidence for activation of microglia in patients with psychiatric illnesses. Neuroscience letters. vol 271. issue 2. 2000-01-21. PMID:10477118. |
in order to elucidate a potential role of microgliosis in severe psychiatric illnesses, post-mortem frontal cortex and hippocampus of patients with schizophrenia (n = 14) and affective disorder (n = 6) and control specimens (n = 13) were studied. |
2000-01-21 |
2023-08-12 |
human |
| F M Bene. Evidence for altered trisynaptic circuitry in schizophrenic hippocampus. Biological psychiatry. vol 46. issue 5. 1999-12-29. PMID:10472413. |
recent postmortem studies have demonstrated subtle alterations in the hippocampal formation (hipp) of patients with schizophrenia (sz). |
1999-12-29 |
2023-08-12 |
Not clear |
| N Stefanis, S Frangou, J Yakeley, T Sharma, P O'Connell, K Morgan, T Sigmudsson, M Taylor, R Murra. Hippocampal volume reduction in schizophrenia: effects of genetic risk and pregnancy and birth complications. Biological psychiatry. vol 46. issue 5. 1999-12-29. PMID:10472422. |
hippocampal volume reduction in schizophrenia: effects of genetic risk and pregnancy and birth complications. |
1999-12-29 |
2023-08-12 |
Not clear |
| N Stefanis, S Frangou, J Yakeley, T Sharma, P O'Connell, K Morgan, T Sigmudsson, M Taylor, R Murra. Hippocampal volume reduction in schizophrenia: effects of genetic risk and pregnancy and birth complications. Biological psychiatry. vol 46. issue 5. 1999-12-29. PMID:10472422. |
hippocampal volume reduction has been repeatedly demonstrated in schizophrenia. |
1999-12-29 |
2023-08-12 |
Not clear |
| W Zhang, B Pouzet, A L Jongen-Rêlo, I Weiner, J Feldo. Disruption of prepulse inhibition following N-methyl-D-aspartate infusion into the ventral hippocampus is antagonized by clozapine but not by haloperidol: a possible model for the screening of atypical antipsychotics. Neuroreport. vol 10. issue 12. 1999-12-21. PMID:10574365. |
since disruption of ppi is considered to constitute an animal model of schizophrenia that is related to the deficit of sensorimotor gating observed in schizophrenic patients, these results suggest that ppi disruption induced by intra-ventral hippocampal infusions of nmda may serve as an animal model for the selective detection of atypical antipsychotics. |
1999-12-21 |
2023-08-12 |
Not clear |
| M P Vawter, A L Howard, T M Hyde, J E Kleinman, W J Free. Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523820. |
alterations of hippocampal secreted n-cam in bipolar disorder and synaptophysin in schizophrenia. |
1999-12-10 |
2023-08-12 |
Not clear |
| M P Vawter, A L Howard, T M Hyde, J E Kleinman, W J Free. Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523820. |
schizophrenia and bipolar disorder have both been linked to structural abnormalities of the hippocampus, which is consistent with a neurodevelopmental anomaly. |
1999-12-10 |
2023-08-12 |
Not clear |
| M P Vawter, A L Howard, T M Hyde, J E Kleinman, W J Free. Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523820. |
one isoform of the neural cell adhesion molecule (n-cam) protein, cytosolic n-cam 105-115 kda, was previously shown to be increased in schizophrenia in the hippocampus and prefrontal cortex. |
1999-12-10 |
2023-08-12 |
Not clear |
| M P Vawter, A L Howard, T M Hyde, J E Kleinman, W J Free. Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523820. |
in the present study, the secreted isoform of n-cam (sec n-cam), synaptophysin, and actin proteins were measured in the hippocampus of controls, suicide victims, and patients with bipolar disorder or schizophrenia by quantitative western immunoblotting. |
1999-12-10 |
2023-08-12 |
Not clear |
| M P Vawter, A L Howard, T M Hyde, J E Kleinman, W J Free. Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523820. |
the results offer further evidence of differences in protein expression between bipolar disorder and schizophrenia in the hippocampus, which is consistent with a distinct neuropathology for each neuropsychiatric disorder. |
1999-12-10 |
2023-08-12 |
Not clear |
| E C Mallard, A Rehn, S Rees, M Tolcos, D Copolo. Ventriculomegaly and reduced hippocampal volume following intrauterine growth-restriction: implications for the aetiology of schizophrenia. Schizophrenia research. vol 40. issue 1. 1999-11-30. PMID:10541002. |
ventriculomegaly and reduced hippocampal volume following intrauterine growth-restriction: implications for the aetiology of schizophrenia. |
1999-11-30 |
2023-08-12 |
Not clear |
| S A Chance, J R Highley, M M Esiri, T J Cro. Fiber content of the fornix in schizophrenia: lack of evidence for a primary limbic encephalopathy. The American journal of psychiatry. vol 156. issue 11. 1999-11-16. PMID:10553734. |
there have been claims that schizophrenia is a disease of the limbic circuit and that the volume of the hippocampus and its content of neurons are low in schizophrenia. |
1999-11-16 |
2023-08-12 |
Not clear |
| J Court, D Spurden, S Lloyd, I McKeith, C Ballard, N Cairns, R Kerwin, R Perry, E Perr. Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus. Journal of neurochemistry. vol 73. issue 4. 1999-10-14. PMID:10501205. |
neuronal nicotinic receptors have been implicated in schizophrenia on the basis of the high incidence of tobacco smoking in patients, abnormalities in cytisine and alpha-bungarotoxin (alphabgt) binding in the hippocampus, and linkage between auditory p50 deficits and the region of chromosome 15 coding the alpha7 subunit. |
1999-10-14 |
2023-08-12 |
Not clear |