| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Heckers, S L Rauch, D Goff, C R Savage, D L Schacter, A J Fischman, N M Alper. Impaired recruitment of the hippocampus during conscious recollection in schizophrenia. Nature neuroscience. vol 1. issue 4. 1999-04-21. PMID:10195166. |
this finding provides the first evidence of hippocampal dysfunction during episodic memory retrieval in schizophrenia. |
1999-04-21 |
2023-08-12 |
Not clear |
| C Gomes-Trolin, M Yassin, C G Gottfries, B Regland, B Grenfeldt, J Hallman, J Prince, L Orelan. Erythrocyte and brain methionine adenosyltransferase activities in patients with schizophrenia. Journal of neural transmission (Vienna, Austria : 1996). vol 105. issue 10-12. 1999-04-15. PMID:9928898. |
the activity of methionine adenosyltransferase (mat) was investigated in erythrocytes and postmortem brain specimens (cortex gyrus frontalis, hippocampus and thalamus) of patients with schizophrenia treated with neuroleptics. |
1999-04-15 |
2023-08-12 |
rat |
| C Gomes-Trolin, M Yassin, C G Gottfries, B Regland, B Grenfeldt, J Hallman, J Prince, L Orelan. Erythrocyte and brain methionine adenosyltransferase activities in patients with schizophrenia. Journal of neural transmission (Vienna, Austria : 1996). vol 105. issue 10-12. 1999-04-15. PMID:9928898. |
in the regions of cortex gyrus frontalis and hippocampus, but not in thalamus, the values of vmax and km were inversely correlated with the duration of schizophrenia. |
1999-04-15 |
2023-08-12 |
rat |
| S L Eastwood, P J Harriso. Hippocampal and cortical growth-associated protein-43 messenger RNA in schizophrenia. Neuroscience. vol 86. issue 2. 1999-03-16. PMID:9881859. |
hippocampal and cortical growth-associated protein-43 messenger rna in schizophrenia. |
1999-03-16 |
2023-08-12 |
human |
| L Naylor, B Dean, A Pereira, A Mackinnon, A Kouzmenko, D Copolo. No association between the serotonin transporter-linked promoter region polymorphism and either schizophrenia or density of the serotonin transporter in human hippocampus. Molecular medicine (Cambridge, Mass.). vol 4. issue 10. 1999-03-04. PMID:9848084. |
no association between the serotonin transporter-linked promoter region polymorphism and either schizophrenia or density of the serotonin transporter in human hippocampus. |
1999-03-04 |
2023-08-12 |
human |
| L Naylor, B Dean, A Pereira, A Mackinnon, A Kouzmenko, D Copolo. No association between the serotonin transporter-linked promoter region polymorphism and either schizophrenia or density of the serotonin transporter in human hippocampus. Molecular medicine (Cambridge, Mass.). vol 4. issue 10. 1999-03-04. PMID:9848084. |
this study attempts to determine whether there is an association between 5-httlpr genotype and schizophrenia or the binding of [3h]paroxetine to the human hippocampal 5-htt. |
1999-03-04 |
2023-08-12 |
human |
| D Velakoulis, C Pantelis, P D McGorry, P Dudgeon, W Brewer, M Cook, P Desmond, N Bridle, P Tierney, V Murrie, B Singh, D Copolo. Hippocampal volume in first-episode psychoses and chronic schizophrenia: a high-resolution magnetic resonance imaging study. Archives of general psychiatry. vol 56. issue 2. 1999-03-02. PMID:10025437. |
hippocampal volume in first-episode psychoses and chronic schizophrenia: a high-resolution magnetic resonance imaging study. |
1999-03-02 |
2023-08-12 |
Not clear |
| D Velakoulis, C Pantelis, P D McGorry, P Dudgeon, W Brewer, M Cook, P Desmond, N Bridle, P Tierney, V Murrie, B Singh, D Copolo. Hippocampal volume in first-episode psychoses and chronic schizophrenia: a high-resolution magnetic resonance imaging study. Archives of general psychiatry. vol 56. issue 2. 1999-03-02. PMID:10025437. |
it has been proposed that the hippocampus is a potential site for a neurodevelopmental lesion in schizophrenia. |
1999-03-02 |
2023-08-12 |
Not clear |
| J H Callicott, M F Egan, A Bertolino, V S Mattay, F J Langheim, J A Frank, D R Weinberge. Hippocampal N-acetyl aspartate in unaffected siblings of patients with schizophrenia: a possible intermediate neurobiological phenotype. Biological psychiatry. vol 44. issue 10. 1999-02-05. PMID:9821558. |
hippocampal n-acetyl aspartate in unaffected siblings of patients with schizophrenia: a possible intermediate neurobiological phenotype. |
1999-02-05 |
2023-08-12 |
Not clear |
| J H Callicott, M F Egan, A Bertolino, V S Mattay, F J Langheim, J A Frank, D R Weinberge. Hippocampal N-acetyl aspartate in unaffected siblings of patients with schizophrenia: a possible intermediate neurobiological phenotype. Biological psychiatry. vol 44. issue 10. 1999-02-05. PMID:9821558. |
we sought evidence of such phenotypes using magnetic resonance spectroscopy based on previously described regional abnormalities in levels of the neuronal marker n-acetyl-aspartate (naa) in the hippocampal area and dorsolateral prefrontal cortex of patients with schizophrenia. |
1999-02-05 |
2023-08-12 |
Not clear |
| B K Lipska, H A al-Amin, D R Weinberge. Excitotoxic lesions of the rat medial prefrontal cortex. Effects on abnormal behaviors associated with neonatal hippocampal damage. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 19. issue 6. 1999-01-29. PMID:9803421. |
neonatal excitotoxic damage of the ventral hippocampus (vh) is a heuristic model of schizophrenia. |
1999-01-29 |
2023-08-12 |
rat |
| M P Vawter, J J Hemperly, T M Hyde, S E Bachus, D M VanderPutten, A L Howard, H E Cannon-Spoor, M T McCoy, M J Webster, J E Kleinman, W J Free. VASE-containing N-CAM isoforms are increased in the hippocampus in bipolar disorder but not schizophrenia. Experimental neurology. vol 154. issue 1. 1999-01-19. PMID:9875262. |
vase-containing n-cam isoforms are increased in the hippocampus in bipolar disorder but not schizophrenia. |
1999-01-19 |
2023-08-12 |
Not clear |
| P O'Donnell, A A Grac. Phencyclidine interferes with the hippocampal gating of nucleus accumbens neuronal activity in vivo. Neuroscience. vol 87. issue 4. 1998-12-30. PMID:9759970. |
this action of phencyclidine is proposed to impair the flow of cortical information through the nucleus accumbens, and thereby mimic the consequences of the hippocampal deficit proposed to contribute to the pathophysiology of schizophrenia. |
1998-12-30 |
2023-08-12 |
human |
| J G Csernansky, S Joshi, L Wang, J W Haller, M Gado, J P Miller, U Grenander, M I Mille. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 19. 1998-10-26. PMID:9736749. |
hippocampal morphometry in schizophrenia by high dimensional brain mapping. |
1998-10-26 |
2023-08-12 |
human |
| J G Csernansky, S Joshi, L Wang, J W Haller, M Gado, J P Miller, U Grenander, M I Mille. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 19. 1998-10-26. PMID:9736749. |
theories of the pathophysiology of schizophrenia have implicated the hippocampus, but controversy remains regarding hippocampal abnormalities in patients with schizophrenia. |
1998-10-26 |
2023-08-12 |
human |
| J G Csernansky, S Joshi, L Wang, J W Haller, M Gado, J P Miller, U Grenander, M I Mille. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 19. 1998-10-26. PMID:9736749. |
to resolve this controversy, high dimensional transformations of a computerized brain template were used to compare hippocampal volumes and shape characteristics in 15 matched pairs of schizophrenia and control subjects. |
1998-10-26 |
2023-08-12 |
human |
| J G Csernansky, S Joshi, L Wang, J W Haller, M Gado, J P Miller, U Grenander, M I Mille. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 19. 1998-10-26. PMID:9736749. |
in the schizophrenia subjects, hippocampal shape deformations were found to be localized to subregions of the structure that send projections to prefrontal cortex. |
1998-10-26 |
2023-08-12 |
human |
| J G Csernansky, S Joshi, L Wang, J W Haller, M Gado, J P Miller, U Grenander, M I Mille. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 19. 1998-10-26. PMID:9736749. |
the results of this study demonstrate that abnormalities of hippocampal anatomy occur in schizophrenia and support current hypotheses that schizophrenia involves a disturbance of hippocampal-prefrontal connections. |
1998-10-26 |
2023-08-12 |
human |
| A Bertolino, S Kumra, J H Callicott, V S Mattay, R M Lestz, L Jacobsen, I S Barnett, J H Duyn, J A Frank, J L Rapoport, D R Weinberge. Common pattern of cortical pathology in childhood-onset and adult-onset schizophrenia as identified by proton magnetic resonance spectroscopic imaging. The American journal of psychiatry. vol 155. issue 10. 1998-10-20. PMID:9766769. |
previous 1h-mrsi studies of adult patients with schizophrenia showed small naa relative signals in the hippocampal area and in the dorsolateral prefrontal cortex in comparison with healthy subjects. |
1998-10-20 |
2023-08-12 |
human |
| A Bertolino, S Kumra, J H Callicott, V S Mattay, R M Lestz, L Jacobsen, I S Barnett, J H Duyn, J A Frank, J L Rapoport, D R Weinberge. Common pattern of cortical pathology in childhood-onset and adult-onset schizophrenia as identified by proton magnetic resonance spectroscopic imaging. The American journal of psychiatry. vol 155. issue 10. 1998-10-20. PMID:9766769. |
as part of a program to address the pathophysiological continuity between childhood-onset and adult-onset schizophrenia, the authors performed 1h-mrsi of patients with childhood-onset schizophrenia to specifically test whether the hippocampal area and dorsolateral prefrontal cortex show the same abnormalities as seen in adult-onset schizophrenia. |
1998-10-20 |
2023-08-12 |
human |