| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S L Eastwood, P J Harriso. Detection and quantification of hippocampal synaptophysin messenger RNA in schizophrenia using autoclaved, formalin-fixed, paraffin wax-embedded sections. Neuroscience. vol 93. issue 1. 1999-10-08. PMID:10430474. |
detection and quantification of hippocampal synaptophysin messenger rna in schizophrenia using autoclaved, formalin-fixed, paraffin wax-embedded sections. |
1999-10-08 |
2023-08-12 |
human |
| H G Bernstein, G Grecksch, A Becker, V Höllt, B Bogert. Cellular changes in rat brain areas associated with neonatal hippocampal damage. Neuroreport. vol 10. issue 11. 1999-09-30. PMID:10439454. |
the neonatal destruction of the ventral hippocampus was introduced as a model to recreate features of schizophrenia in the rat. |
1999-09-30 |
2023-08-12 |
rat |
| A Becker, G Grecksch, H G Bernstein, V Höllt, B Bogert. Social behaviour in rats lesioned with ibotenic acid in the hippocampus: quantitative and qualitative analysis. Psychopharmacology. vol 144. issue 4. 1999-09-28. PMID:10435405. |
neonatal ibotenic acid lesion of the ventral hippocampus was proposed as a relevant animal model of schizophrenia reflecting positive as well as negative symptoms of this disease. |
1999-09-28 |
2023-08-12 |
rat |
| H Schroeder, G Grecksch, A Becker, B Bogerts, V Hoell. Alterations of the dopaminergic and glutamatergic neurotransmission in adult rats with postnatal ibotenic acid hippocampal lesion. Psychopharmacology. vol 145. issue 1. 1999-09-14. PMID:10445373. |
the present data are in agreement with the hypothesis of hyperactive dopamine and hypoactive glutamate systems in schizophrenia and are discussed in the light of schizophrenia-like behavioral changes in rats after postnatal hippocampal ibo lesion. |
1999-09-14 |
2023-08-12 |
rat |
| V Klimek, G Rajkowska, S N Luker, G Dilley, H Y Meltzer, J C Overholser, C A Stockmeier, G A Ordwa. Brain noradrenergic receptors in major depression and schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 1. 1999-09-01. PMID:10379521. |
the binding of [125i]p-iodoclonidine to alpha-2, and/or [125i]iodopindolol to beta-1 and beta-2 adrenoceptors was measured in right prefrontal cortex (brodmann's area 10) and right hippocampus from subjects with dsm-iii-r diagnoses of major depression (n = 15) or schizophrenia (n = 8) as well as from control subjects (n = 20). |
1999-09-01 |
2023-08-12 |
human |
| V Klimek, G Rajkowska, S N Luker, G Dilley, H Y Meltzer, J C Overholser, C A Stockmeier, G A Ordwa. Brain noradrenergic receptors in major depression and schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 1. 1999-09-01. PMID:10379521. |
alterations in beta-1 adrenoceptor binding in the hippocampus of schizophrenics provide further evidence for a role of central noradrenergic neurons in the neurochemical pathology of schizophrenia. |
1999-09-01 |
2023-08-12 |
human |
| R F Deicken, M Pegues, D Amen. Reduced hippocampal N-acetylaspartate without volume loss in schizophrenia. Schizophrenia research. vol 37. issue 3. 1999-08-26. PMID:10403193. |
reduced hippocampal n-acetylaspartate without volume loss in schizophrenia. |
1999-08-26 |
2023-08-12 |
human |
| R F Deicken, M Pegues, D Amen. Reduced hippocampal N-acetylaspartate without volume loss in schizophrenia. Schizophrenia research. vol 37. issue 3. 1999-08-26. PMID:10403193. |
the objective of this study was to obtain quantitative measures of hippocampal volume and hippocampal naa to determine if there was evidence for hippocampal neuronal dysfunction or neuronal loss in schizophrenia. |
1999-08-26 |
2023-08-12 |
human |
| R F Deicken, M Pegues, D Amen. Reduced hippocampal N-acetylaspartate without volume loss in schizophrenia. Schizophrenia research. vol 37. issue 3. 1999-08-26. PMID:10403193. |
relative to the control group, the patients with schizophrenia demonstrated no change in hippocampal volumes bilaterally, but significantly decreased naa in the hippocampal regions bilaterally. |
1999-08-26 |
2023-08-12 |
human |
| J M Brezun, A Daszut. Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats. Neuroscience. vol 89. issue 4. 1999-07-22. PMID:10362289. |
indeed, lack of 5-hydroxytryptamine in the hippocampus has been associated with cognitive disorders, such as depression, schizophrenia and alzheimer's disease. |
1999-07-22 |
2023-08-12 |
human |
| b' S M Lillrank, B K Lipska, D R Weinberger, B B Fredholm, K Fuxe, S Ferr\\xc3\\xa. Adenosine and dopamine receptor antagonist binding in the rat ventral and dorsal striatum: lack of changes after a neonatal bilateral lesion of the ventral hippocampus. Neurochemistry international. vol 34. issue 3. 1999-07-15. PMID:10355490.' |
the experiments were also performed in rats with a neonatal bilateral lesion of the ventral hippocampus (vh), a possible animal model of schizophrenia. |
1999-07-15 |
2023-08-12 |
rat |
| G Grecksch, H G Bernstein, A Becker, V Höllt, B Bogert. Disruption of latent inhibition in rats with postnatal hippocampal lesions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 20. issue 6. 1999-06-24. PMID:10327422. |
these results demonstrate disturbances in early postnatal hippocampal lesioned rats comparable with those seen in schizophrenic patients, thus further validating this procedure as a useful animal model of some aspects of schizophrenia. |
1999-06-24 |
2023-08-12 |
rat |
| P F Edgar, S J Schonberger, B Dean, R L Faull, R Kydd, G J Coope. A comparative proteome analysis of hippocampal tissue from schizophrenic and Alzheimer's disease individuals. Molecular psychiatry. vol 4. issue 2. 1999-06-15. PMID:10208449. |
protein changes involved 6% of the assessed ad hippocampal proteome, whereas, in schizophrenia protein changes involved less than 1% of the assessed hippocampal proteome. |
1999-06-15 |
2023-08-12 |
Not clear |
| B Dean, E Scarr, R Bradbury, D Copolo. Decreased hippocampal (CA3) NMDA receptors in schizophrenia. Synapse (New York, N.Y.). vol 32. issue 1. 1999-06-01. PMID:10188640. |
decreased hippocampal (ca3) nmda receptors in schizophrenia. |
1999-06-01 |
2023-08-12 |
Not clear |
| D R Weinberge. Cell biology of the hippocampal formation in schizophrenia. Biological psychiatry. vol 45. issue 4. 1999-05-13. PMID:10071707. |
these data about the cellular and molecular biology of the hf in schizophrenia are different from that found in a number of conditions associated with hippocampal damage, including excitotoxicity, epilepsy, alcoholism, alzheimer's disease, steroid neurotoxicity, and normal aging. |
1999-05-13 |
2023-08-12 |
Not clear |
| C Tamming. Glutamatergic aspects of schizophrenia. The British journal of psychiatry. Supplement. issue 37. 1999-05-10. PMID:10211134. |
diminished glutamatergic neurotransmission in the hippocampal glutamate-mediated efferent pathways and cerebral dysfunction in the hippocampus and its target areas, particularly the anterior cingulate cortex, may underlie some of the clinical manifestations of schizophrenia. |
1999-05-10 |
2023-08-12 |
Not clear |
| P J Harriso. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain : a journal of neurology. vol 122 ( Pt 4). 1999-05-06. PMID:10219775. |
other cytoarchitectural features of schizophrenia which are often discussed, notably entorhinal cortex heterotopias and hippocampal neuronal disarray, remain to be confirmed. |
1999-05-06 |
2023-08-12 |
Not clear |
| P J Harriso. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain : a journal of neurology. vol 122 ( Pt 4). 1999-05-06. PMID:10219775. |
a case can be made for impairment of hippocampal and corticocortical excitatory pathways, but in general the relationship between neurochemical findings (which centre upon dopamine, 5-hydroxytryptamine, glutamate and gaba systems) and the neuropathology of schizophrenia is unclear. |
1999-05-06 |
2023-08-12 |
Not clear |
| P J Harriso. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain : a journal of neurology. vol 122 ( Pt 4). 1999-05-06. PMID:10219775. |
functional imaging data indicate that the pathophysiology of schizophrenia reflects aberrant activity in, and integration of, the components of distributed circuits involving the prefrontal cortex, hippocampus and certain subcortical structures. |
1999-05-06 |
2023-08-12 |
Not clear |
| S Heckers, S L Rauch, D Goff, C R Savage, D L Schacter, A J Fischman, N M Alper. Impaired recruitment of the hippocampus during conscious recollection in schizophrenia. Nature neuroscience. vol 1. issue 4. 1999-04-21. PMID:10195166. |
impaired recruitment of the hippocampus during conscious recollection in schizophrenia. |
1999-04-21 |
2023-08-12 |
Not clear |