| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B D Pearce, N M Valadi, C L Po, A H Mille. Viral infection of developing GABAergic neurons in a model of hippocampal disinhibition. Neuroreport. vol 11. issue 11. 2001-01-04. PMID:10943699. |
mechanisms by which perinatal viral infections can disrupt hippocampal development and cause selective neuronal death may have implications for temporal lobe epilepsy and schizophrenia. |
2001-01-04 |
2023-08-12 |
rat |
| G Le Pen, A J Grottick, G A Higgins, J R Martin, F Jenck, J L Morea. Spatial and associative learning deficits induced by neonatal excitotoxic hippocampal damage in rats: further evaluation of an animal model of schizophrenia. Behavioural pharmacology. vol 11. issue 3-4. 2000-12-14. PMID:11103880. |
spatial and associative learning deficits induced by neonatal excitotoxic hippocampal damage in rats: further evaluation of an animal model of schizophrenia. |
2000-12-14 |
2023-08-12 |
rat |
| G Le Pen, A J Grottick, G A Higgins, J R Martin, F Jenck, J L Morea. Spatial and associative learning deficits induced by neonatal excitotoxic hippocampal damage in rats: further evaluation of an animal model of schizophrenia. Behavioural pharmacology. vol 11. issue 3-4. 2000-12-14. PMID:11103880. |
neonatal ventral hippocampal lesions in the rat result in post-pubertal onset of behavioural abnormalities, modelling some aspects of schizophrenia. |
2000-12-14 |
2023-08-12 |
rat |
| P F Liddle, C J Lane, E T Nga. Immediate effects of risperidone on cortico-striato-thalamic loops and the hippocampus. The British journal of psychiatry : the journal of mental science. vol 177. 2000-12-08. PMID:11059992. |
functional imaging studies indicate that delusions and hallucinations in schizophrenia are associated with overactivity of the left hippocampus and ventral striatum. |
2000-12-08 |
2023-08-12 |
Not clear |
| J M Crook, E Tomaskovic-Crook, D L Copolov, B Dea. Decreased muscarinic receptor binding in subjects with schizophrenia: a study of the human hippocampal formation. Biological psychiatry. vol 48. issue 5. 2000-11-16. PMID:10978721. |
patients with schizophrenia show impaired learning and memory and hippocampal dysfunction. |
2000-11-16 |
2023-08-12 |
human |
| K Kato, T Shishido, M Ono, K Shishido, M Kobayashi, H Suzuki, T Nabeshima, H Furukawa, S Niw. Effects of phencyclidine on behavior and extracellular levels of dopamine and its metabolites in neonatal ventral hippocampal damaged rats. Psychopharmacology. vol 150. issue 2. 2000-11-07. PMID:10907669. |
the use of neonatal hippocampal lesioned rats is well established in animal models of schizophrenia. |
2000-11-07 |
2023-08-12 |
rat |
| M Maier, J Mellers, B Toone, M Trimble, M A Ro. Schizophrenia, temporal lobe epilepsy and psychosis: an in vivo magnetic resonance spectroscopy and imaging study of the hippocampus/amygdala complex. Psychological medicine. vol 30. issue 3. 2000-11-01. PMID:10883713. |
we have used proton magnetic resonance imaging and spectroscopy to measure hippocampus/amygdala volumes and anterior hippocampal metabolite concentrations (n-acetyl aspartate (naa), creatine/phosphocreatine and choline) in subjects with temporal lobe epilepsy (tle), schizophrenia and in normal controls. |
2000-11-01 |
2023-08-12 |
human |
| D Gothelf, N Soreni, R P Nachman, S Tyano, Y Hiss, O Reiner, A Weizma. Evidence for the involvement of the hippocampus in the pathophysiology of schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 5. 2000-10-30. PMID:10974611. |
evidence for the involvement of the hippocampus in the pathophysiology of schizophrenia. |
2000-10-30 |
2023-08-12 |
Not clear |
| D Gothelf, N Soreni, R P Nachman, S Tyano, Y Hiss, O Reiner, A Weizma. Evidence for the involvement of the hippocampus in the pathophysiology of schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 5. 2000-10-30. PMID:10974611. |
the hippocampus, a medial temporal lobe structure, is often considered to play an important role in the pathophysiology of schizophrenia. |
2000-10-30 |
2023-08-12 |
Not clear |
| D Gothelf, N Soreni, R P Nachman, S Tyano, Y Hiss, O Reiner, A Weizma. Evidence for the involvement of the hippocampus in the pathophysiology of schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 5. 2000-10-30. PMID:10974611. |
this article describes animal models, structural, histological, molecular biology, and neuropsychological evidence for the involvement of the hippocampus in the pathophysiology of schizophrenia. |
2000-10-30 |
2023-08-12 |
Not clear |
| D Gothelf, N Soreni, R P Nachman, S Tyano, Y Hiss, O Reiner, A Weizma. Evidence for the involvement of the hippocampus in the pathophysiology of schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 5. 2000-10-30. PMID:10974611. |
more comprehensive and focused hippocampal research in schizophrenia is required to elucidate the contribution of this intriguing brain structure to the pathophysiology of schizophrenia. |
2000-10-30 |
2023-08-12 |
Not clear |
| K Niemann, A Hammers, V A Coenen, A Thron, J Klosterkötte. Evidence of a smaller left hippocampus and left temporal horn in both patients with first episode schizophrenia and normal control subjects. Psychiatry research. vol 99. issue 2. 2000-10-11. PMID:10963985. |
evidence of a smaller left hippocampus and left temporal horn in both patients with first episode schizophrenia and normal control subjects. |
2000-10-11 |
2023-08-12 |
human |
| L L Altshuler, G Bartzokis, T Grieder, J Curran, T Jimenez, K Leight, J Wilkins, R Gerner, J Mint. An MRI study of temporal lobe structures in men with bipolar disorder or schizophrenia. Biological psychiatry. vol 48. issue 2. 2000-09-21. PMID:10903411. |
hippocampal atrophy has been described in postmortem and magnetic resonance imaging studies of schizophrenia. |
2000-09-21 |
2023-08-12 |
Not clear |
| P R Szeszko, R M Bilder, T Lencz, M Ashtari, R S Goldman, G Reiter, H Wu, J A Lieberma. Reduced anterior cingulate gyrus volume correlates with executive dysfunction in men with first-episode schizophrenia. Schizophrenia research. vol 43. issue 2-3. 2000-09-19. PMID:10858628. |
orbital frontal region) would be significantly and selectively correlated with executive and motor dysfunction in patients with schizophrenia as previously reported for the anterior hippocampal region. |
2000-09-19 |
2023-08-12 |
Not clear |
| S L Eastwood, P J Harriso. Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression: a study of complexin mRNAs. Molecular psychiatry. vol 5. issue 4. 2000-09-14. PMID:10889554. |
these data replicate the finding of decreased cx i and cx ii expression in the hippocampus in schizophrenia and show a similar or greater abnormality in bipolar disorder. |
2000-09-14 |
2023-08-12 |
rat |
| J Behr, T Gloveli, D Schmitz, U Heineman. Dopamine depresses excitatory synaptic transmission onto rat subicular neurons via presynaptic D1-like dopamine receptors. Journal of neurophysiology. vol 84. issue 1. 2000-09-07. PMID:10899189. |
schizophrenia is considered to be associated with an abnormal functioning of the hippocampal output. |
2000-09-07 |
2023-08-12 |
rat |
| N Durany, R Zöchling, K W Boissl, W Paulus, G Ransmayr, T Tatschner, W Danielczyk, K Jellinger, J Deckert, P Riedere. Human post-mortem striatal alpha4beta2 nicotinic acetylcholine receptor density in schizophrenia and Parkinson's syndrome. Neuroscience letters. vol 287. issue 2. 2000-08-17. PMID:10854724. |
the density of nicotinic alpha4beta2 receptors, which are believed to largely mediate nicotine's effects, has been reported to be decreased in post-mortem hippocampus of patients with schizophrenia. |
2000-08-17 |
2023-08-12 |
human |
| P Delamillieure, J M Constans, J Fernandez, S Dollfu. [Magnetic resonance spectroscopy in schizophrenia]. L'Encephale. vol 26. issue 1. 2000-08-15. PMID:10875059. |
the prefrontal cortex, the hippocampus and the basal ganglia have all been implicated in the pathophysiology of schizophrenia. |
2000-08-15 |
2023-08-12 |
Not clear |
| S E Arnol. Cellular and molecular neuropathology of the parahippocampal region in schizophrenia. Annals of the New York Academy of Sciences. vol 911. 2000-08-09. PMID:10911880. |
the entorhinal cortex, subiculum, and hippocampus have been regions of great interest in both clinical and neuropathological investigations of schizophrenia. |
2000-08-09 |
2023-08-12 |
Not clear |
| F M Benes, S Berrett. Amygdalo-entorhinal inputs to the hippocampal formation in relation to schizophrenia. Annals of the New York Academy of Sciences. vol 911. 2000-08-09. PMID:10911881. |
overall, it seems plausible that an increase of excitatory activity entering the hippocampus from the basolateral complex via both direct and indirect pathways may make a significant contribution to the pathophysiology of schizophrenia. |
2000-08-09 |
2023-08-12 |
human |