| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Therese M Roth, Elizabeth M Petty, Kate F Baral. The role of steroid hormones in the NF1 phenotype: focus on pregnancy. American journal of medical genetics. Part A. vol 146A. issue 12. 2008-06-16. PMID:18481270. |
the number and size of neurofibromas in nf1 patients has been shown to increase during pregnancy, with, in some cases, post-partum regression, which suggests hormonal involvement in this increase. |
2008-06-16 |
2023-08-12 |
human |
| Hildegard Kehrer-Sawatzki, Eva Schmid, Carsten Fünsterer, Lan Kluwe, Victor-Felix Mautne. Absence of cutaneous neurofibromas in an NF1 patient with an atypical deletion partially overlapping the common 1.4 Mb microdeleted region. American journal of medical genetics. Part A. vol 146A. issue 6. 2008-04-16. PMID:18265407. |
absence of cutaneous neurofibromas in an nf1 patient with an atypical deletion partially overlapping the common 1.4 mb microdeleted region. |
2008-04-16 |
2023-08-12 |
Not clear |
| Hildegard Kehrer-Sawatzki, Eva Schmid, Carsten Fünsterer, Lan Kluwe, Victor-Felix Mautne. Absence of cutaneous neurofibromas in an NF1 patient with an atypical deletion partially overlapping the common 1.4 Mb microdeleted region. American journal of medical genetics. Part A. vol 146A. issue 6. 2008-04-16. PMID:18265407. |
nf1 patients with gross deletions have been reported to manifest a more severe clinical phenotype than nf1 patients with intragenic mutations, and display early onset and extensive growth of neurofibromas. |
2008-04-16 |
2023-08-12 |
Not clear |
| Hildegard Kehrer-Sawatzki, Eva Schmid, Carsten Fünsterer, Lan Kluwe, Victor-Felix Mautne. Absence of cutaneous neurofibromas in an NF1 patient with an atypical deletion partially overlapping the common 1.4 Mb microdeleted region. American journal of medical genetics. Part A. vol 146A. issue 6. 2008-04-16. PMID:18265407. |
it has been suggested that the deletion of a neighboring gene or genes in addition to the nf1 gene may modify the expression of the disease, particularly with regard to the high burden of cutaneous neurofibromas. |
2008-04-16 |
2023-08-12 |
Not clear |
| Hildegard Kehrer-Sawatzki, Eva Schmid, Carsten Fünsterer, Lan Kluwe, Victor-Felix Mautne. Absence of cutaneous neurofibromas in an NF1 patient with an atypical deletion partially overlapping the common 1.4 Mb microdeleted region. American journal of medical genetics. Part A. vol 146A. issue 6. 2008-04-16. PMID:18265407. |
thus, atypical deletions partially overlapping with the common 1.4 mb microdeletion interval could prove useful in identifying possible genetic modifiers in the nf1 gene region whose haploinsufficiency might promote neurofibroma growth. |
2008-04-16 |
2023-08-12 |
Not clear |
| Jianqiang Wu, Jon P Williams, Tilat A Rizvi, Jennifer J Kordich, David Witte, Dies Meijer, Anat O Stemmer-Rachamimov, Jose A Cancelas, Nancy Ratne. Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer cell. vol 13. issue 2. 2008-03-26. PMID:18242511. |
plexiform and dermal neurofibromas and pigmentation are caused by nf1 loss in desert hedgehog-expressing cells. |
2008-03-26 |
2023-08-12 |
Not clear |
| Jianqiang Wu, Jon P Williams, Tilat A Rizvi, Jennifer J Kordich, David Witte, Dies Meijer, Anat O Stemmer-Rachamimov, Jose A Cancelas, Nancy Ratne. Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer cell. vol 13. issue 2. 2008-03-26. PMID:18242511. |
neurofibromatosis type 1 (nf1) mutation predisposes to benign peripheral nerve (glial) tumors called neurofibromas. |
2008-03-26 |
2023-08-12 |
Not clear |
| Jianqiang Wu, Jon P Williams, Tilat A Rizvi, Jennifer J Kordich, David Witte, Dies Meijer, Anat O Stemmer-Rachamimov, Jose A Cancelas, Nancy Ratne. Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer cell. vol 13. issue 2. 2008-03-26. PMID:18242511. |
the point(s) in development when nf1 loss promotes neurofibroma formation are unknown. |
2008-03-26 |
2023-08-12 |
Not clear |
| Jianqiang Wu, Jon P Williams, Tilat A Rizvi, Jennifer J Kordich, David Witte, Dies Meijer, Anat O Stemmer-Rachamimov, Jose A Cancelas, Nancy Ratne. Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer cell. vol 13. issue 2. 2008-03-26. PMID:18242511. |
we suggest that timing of nf1 mutation is critical for neurofibroma formation. |
2008-03-26 |
2023-08-12 |
Not clear |
| Nancy M Joseph, Jack T Mosher, Johanna Buchstaller, Paige Snider, Paul E McKeever, Megan Lim, Simon J Conway, Luis F Parada, Yuan Zhu, Sean J Morriso. The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer cell. vol 13. issue 2. 2008-03-26. PMID:18242513. |
neurofibromatosis is caused by the loss of neurofibromin (nf1), leading to peripheral nervous system (pns) tumors, including neurofibromas and malignant peripheral nerve sheath tumors (mpnsts). |
2008-03-26 |
2023-08-12 |
mouse |
| A Sahgal, D Chou, C Ames, L Ma, K Lamborn, K Huang, C Chuang, A Aiken, P Petti, P Weinstein, D Larso. Image-guided robotic stereotactic body radiotherapy for benign spinal tumors: theUniversity of California San Francisco preliminary experience. Technology in cancer research & treatment. vol 6. issue 6. 2008-03-04. PMID:17994789. |
two tumors were neurofibromas (both in nf1 patients), and the third was an intramedullary hemangioblastoma. |
2008-03-04 |
2023-08-12 |
Not clear |
| T Tucker, P Birch, D M Savoy, J M Friedma. Increased dental caries in people with neurofibromatosis 1. Clinical genetics. vol 72. issue 6. 2008-01-22. PMID:18001351. |
neurofibromatosis 1 (nf1) is an autosomal dominant disease that is associated with multiple café-au-lait spots and neurofibromas. |
2008-01-22 |
2023-08-12 |
Not clear |
| T Tucker, P Birch, D M Savoy, J M Friedma. Increased dental caries in people with neurofibromatosis 1. Clinical genetics. vol 72. issue 6. 2008-01-22. PMID:18001351. |
dental abnormalities can occur in association with oral neurofibromas but have not otherwise been described in people with nf1. |
2008-01-22 |
2023-08-12 |
Not clear |
| G De Toma, C Letizia, G Cavallaro, A Polistena, D Cotesta, L Petramala, R Porciello, S Giustini, S Calvier. Adrenal pheochromocytoma and jejunal neurofibroma in type 1 neurofibromatosis: report of a case. Il Giornale di chirurgia. vol 28. issue 5. 2008-01-03. PMID:17547785. |
neurofibromatosis type 1 (nf1), known as von recklinghausen's disease, is characterized by presence of café au lait spots, and neurofibromas in the skin or along the course of peripheral nerves. |
2008-01-03 |
2023-08-12 |
Not clear |
| J R Leonard, R E Ferner, N Thomas, D H Gutman. Cervical cord compression from plexiform neurofibromas in neurofibromatosis 1. Journal of neurology, neurosurgery, and psychiatry. vol 78. issue 12. 2007-12-10. PMID:17635968. |
cervical cord compression from cervical root neurofibromas represents an important clinical problem in patients with neurofibromatosis type 1 (nf1), but is rarely reported. |
2007-12-10 |
2023-08-12 |
Not clear |
| Takeshi Miyawaki, Brian Billings, Yaron Har-Shai, Pius Agbenorku, Elisa Kokuba, Andrea Moreira-Gonzalez, Mari Tsukuno, Kunihiro Kurihara, Ian T Jackso. Multicenter study of wound healing in neurofibromatosis and neurofibroma. The Journal of craniofacial surgery. vol 18. issue 5. 2007-12-06. PMID:17912073. |
the analysis was undertaken based on the following points: 1) age and sex at surgery; 2) race of the patients; 3) past and family histories of hypertrophic scar and keloid; 4) surgical site(s); 5) diagnosis, nf1 or solitary neurofibroma; 6) surgical complications; 7) number of reoperations to manage the complications; 8) adjuvant therapy for the tumor; 9) depth of the tumors; and 10) incidence of malignant degeneration. |
2007-12-06 |
2023-08-12 |
Not clear |
| Matthieu Peyre, Augustin Ozanne, Ranjeev Bhangoo, Vitor Pereira, Marc Tadié, Pierre Lasjaunias, Fabrice Parke. Pseudotumoral presentation of a cervical extracranial vertebral artery aneurysm in neurofibromatosis type 1: case report. Neurosurgery. vol 61. issue 3. 2007-11-07. PMID:17881942. |
we report the case of such an aneurysm mimicking a cervical neurofibroma in nf1. |
2007-11-07 |
2023-08-12 |
Not clear |
| Eduard Serra, Eva Pros, Carles García, Eva López, M Lluïsa Gili, Carolina Gómez, Anna Ravella, Gabriel Capellá, Ignacio Blanco, Conxi Lázar. Tumor LOH analysis provides reliable linkage information for prenatal genetic testing of sporadic NF1 patients. Genes, chromosomes & cancer. vol 46. issue 9. 2007-10-30. PMID:17563086. |
here we describe the use of loss of heterozygosity information in neurofibromas to obtain linkage information on the affected nf1 haplotype, which may be applied for prenatal testing in sporadic patients. |
2007-10-30 |
2023-08-12 |
Not clear |
| Nikola Holtkamp, Isis Atallah, Ali-Fuat Okuducu, Jana Mucha, Christian Hartmann, Victor-F Mautner, Reinhard E Friedrich, Christian Mawrin, Andreas von Deimlin. MMP-13 and p53 in the progression of malignant peripheral nerve sheath tumors. Neoplasia (New York, N.Y.). vol 9. issue 8. 2007-09-28. PMID:17786186. |
we therefore examined mpnst from 22 neurofibromatosis type 1 (nf1) patients, 14 non-nf1 patients, and 14 neurofibroma patients for matrix metalloproteinase 13 (mmp-13) expression. |
2007-09-28 |
2023-08-12 |
Not clear |
| Ophélia Maertens, Sofie De Schepper, Jo Vandesompele, Hilde Brems, Ine Heyns, Sandra Janssens, Frank Speleman, Eric Legius, Ludwine Messiae. Molecular dissection of isolated disease features in mosaic neurofibromatosis type 1. American journal of human genetics. vol 81. issue 2. 2007-09-21. PMID:17668375. |
this approach confirmed the biallelic nf1 inactivation in schwann cells in neurofibromas and, for the first time, demonstrated biallelic nf1 inactivation in melanocytes in nf1-related cafe-au-lait macules. |
2007-09-21 |
2023-08-12 |
Not clear |