| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoshimi Arima, Hidemi Hayashi, Kanako Kamata, Takaaki M Goto, Mikako Sasaki, Akira Kuramochi, Hideyuki Say. Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1. Experimental dermatology. vol 19. issue 8. 2011-01-06. PMID:20002172. |
neurofibromas arise from schwann cells with biallelic inactivation of nf1, the gene that encodes neurofibromin. |
2011-01-06 |
2023-08-12 |
human |
| Gill Spurlock, Samantha J L Knight, Nick Thomas, Tim-Rasmus Kiehl, Abhijit Guha, Meena Upadhyay. Molecular evolution of a neurofibroma to malignant peripheral nerve sheath tumor (MPNST) in an NF1 patient: correlation between histopathological, clinical and molecular findings. Journal of cancer research and clinical oncology. vol 136. issue 12. 2010-11-24. PMID:20229272. |
molecular evolution of a neurofibroma to malignant peripheral nerve sheath tumor (mpnst) in an nf1 patient: correlation between histopathological, clinical and molecular findings. |
2010-11-24 |
2023-08-12 |
Not clear |
| Long Dugu, Sayaka Hayashida, Takeshi Nakahara, Lining Xie, Yayoi Iwashita, Xiguang Liu, Hiroshi Uchi, Satoshi Tateuchi, Masakazu Takahara, Yoshinao Oda, Yoichi Moroi, Masutaka Furu. Aberrant expression of tenascin-c and neuronatin in malignant peripheral nerve sheath tumors. European journal of dermatology : EJD. vol 20. issue 5. 2010-11-16. PMID:20610366. |
development of neurofibroma (nf) and its malignant counterpart, malignant peripheral nerve sheath tumor (mpnst), is a hallmark of type i neurofibromatosis (nf1). |
2010-11-16 |
2023-08-12 |
Not clear |
| Talia M Muram-Zborovski, Cecily P Vaughn, David H Viskochil, Heather Hanson, Rong Mao, David A Stevenso. NF1 exon 22 analysis of individuals with the clinical diagnosis of neurofibromatosis type 1. American journal of medical genetics. Part A. vol 152A. issue 8. 2010-11-15. PMID:20602485. |
most nf1 individuals develop age-related tumorigenic manifestations (e.g., neurofibromas), although individuals with a specific 3-bp deletion in exon 22 of nf1 (c.2970_2972delaat) have an attenuated phenotype with primarily pigmentary manifestations. |
2010-11-15 |
2023-08-12 |
Not clear |
| Benjamin Gesundheit, Patricia Parkin, Mark Greenberg, Sylvain Baruchel, Christof Senger, Josef Kapelushnik, Charles Smith, Giannoula Lakka Klemen. The role of angiogenesis in the transformation of plexiform neurofibroma into malignant peripheral nerve sheath tumors in children with neurofibromatosis type 1. Journal of pediatric hematology/oncology. vol 32. issue 7. 2010-10-25. PMID:20686424. |
the role of angiogenesis in the transformation of peripheral neurofibroma (pnf) to malignant peripheral nerve sheath tumor (mpnst) in neurofibromatosis type 1 (nf1) remains elusive and forms the objective of this study. |
2010-10-25 |
2023-08-12 |
Not clear |
| F El Ounani, R Dafir. [Imaging features of neurofibromatosis involving the urinary bladder]. Journal de radiologie. vol 91. issue 5 Pt 1. 2010-09-23. PMID:20657356. |
the imaging features of neurofibromas are fairly characteristic and may often suggest the correct diagnosis, especially in patients with known nf1. |
2010-09-23 |
2023-08-12 |
Not clear |
| Christian Mawri. Critical role of PTEN for development and progression of nerve sheath tumors in neurofibromatosis type 1. Future oncology (London, England). vol 6. issue 4. 2010-08-24. PMID:20373864. |
development of malignant peripheral nerve sheath tumors (mpnsts) from neurofibroma significantly affects the morbidity and mortality of nf1 patients. |
2010-08-24 |
2023-08-12 |
mouse |
| Judith A Murovic, S Charles Cho, Jon Par. Surgical strategies for managing foraminal nerve sheath tumors: the emerging role of CyberKnife ablation. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 19. issue 2. 2010-07-15. PMID:19798517. |
three neurofibromas had associated neurofibromatosis type 1 (nf1). |
2010-07-15 |
2023-08-12 |
Not clear |
| Reinhard E Friedrich, Claudia Stelljes, Christian Hagel, Manfred Giese, Hanna A Scheue. Dysplasia of the orbit and adjacent bone associated with plexiform neurofibroma and ocular disease in 42 NF-1 patients. Anticancer research. vol 30. issue 5. 2010-07-13. PMID:20592374. |
neurofibromas are the hallmark of neurofibromatosis type 1 (nf1). |
2010-07-13 |
2023-08-12 |
Not clear |
| C Bacci, R Sestini, F Ammannati, E Bianchini, T Palladino, M Carella, S Melchionda, L Zelante, L Pap. Multiple spinal ganglioneuromas in a patient harboring a pathogenic NF1 mutation. Clinical genetics. vol 77. issue 3. 2010-07-06. PMID:19863548. |
the patient lacked other nf1 stigmata, such as freckling, lisch nodules and cutaneous neurofibromas. |
2010-07-06 |
2023-08-12 |
Not clear |
| Sushma Kashinath Gabhane, Mrunmayi Nishikant Kotwal, Sudhakar K Bobhat. Segmental neurofibromatosis: a report of 3 cases. Indian journal of dermatology. vol 55. issue 1. 2010-06-25. PMID:20418991. |
the patients with generalized form of nf1 are characterized by multiple café-au-lait spots and neurofibromas and diagnosed easily. |
2010-06-25 |
2023-08-12 |
Not clear |
| Rosalie E Ferne. The neurofibromatoses. Practical neurology. vol 10. issue 2. 2010-06-23. PMID:20308235. |
neurofibromas are characteristic of nf1, a common condition with major skin involvement and many clinical complications. |
2010-06-23 |
2023-08-12 |
Not clear |
| Hiroaki Kobayashi, Gou Kaneko, Koshiro Nishimoto, Atushi Uchid. [A case of pheochromocytoma associated with neurofibromatosis type 1]. Hinyokika kiyo. Acta urologica Japonica. vol 55. issue 12. 2010-02-25. PMID:20048558. |
radiological findings of pheochromocytoma are often similar to those of neurofibroma; therefore, any pheochromocytoma should be excised in hypertensive patients with nf1. |
2010-02-25 |
2023-08-12 |
Not clear |
| Sabrina Titze, Hartmut Peters, Sandra Währisch, Thomas Harder, Katrin Guse, Annegret Buske, Sigrid Tinschert, Anja Harde. Differential MSH2 promoter methylation in blood cells of Neurofibromatosis type 1 (NF1) patients. European journal of human genetics : EJHG. vol 18. issue 1. 2010-02-22. PMID:19639020. |
we aimed to analyze whether dna methylation of mismatch repair gene promoters, known to lead to transcriptional silencing, is associated with increased tumor load in nf1 defined by the number of cutaneous neurofibromas. |
2010-02-22 |
2023-08-12 |
Not clear |
| A M Nyström, S Ekvall, J Allanson, C Edeby, M Elinder, G Holmström, M L Bondeson, G Anneré. Noonan syndrome and neurofibromatosis type I in a family with a novel mutation in NF1. Clinical genetics. vol 76. issue 6. 2010-02-17. PMID:19845691. |
ns is characterized by short stature, heart defect, pectus deformity and facial dysmorphism, whereas skin manifestations, skeletal defects, lisch nodules and neurofibromas are characteristic of nf1. |
2010-02-17 |
2023-08-12 |
Not clear |
| A M Nyström, S Ekvall, J Allanson, C Edeby, M Elinder, G Holmström, M L Bondeson, G Anneré. Noonan syndrome and neurofibromatosis type I in a family with a novel mutation in NF1. Clinical genetics. vol 76. issue 6. 2010-02-17. PMID:19845691. |
we present the clinical and molecular characterization of a family displaying features of both ns and nf1, with complete absence of neurofibromas. |
2010-02-17 |
2023-08-12 |
Not clear |
| Aristides Lytras, George Toli. Reproductive disturbances in multiple neuroendocrine tumor syndromes. Endocrine-related cancer. vol 16. issue 4. 2010-02-16. PMID:19737912. |
lesions such as certain types of ovarian cysts (mas, cnc), pseudogynecomastia due to neurofibromas of the nipple-areola area (nf1), breast disease (cnc and cowden disease (cd)), cysts and 'hypernephroid' tumors of the epididymis or bilateral papillary cystadenomas (mesosalpinx cysts) and endometrioid cystadenomas of the broad ligament (von hippel-lindau disease), testicular sertoli calcifying tumors (cnc, pjs) monolateral or bilateral macroochidism and microlithiasis (mas) may offer diagnostic clues. |
2010-02-16 |
2023-08-12 |
Not clear |
| Oren N Gottfried, David H Viskochil, William T Couldwel. Neurofibromatosis Type 1 and tumorigenesis: molecular mechanisms and therapeutic implications. Neurosurgical focus. vol 28. issue 1. 2010-02-16. PMID:20043723. |
neurofibromatosis type 1 (nf1) is a common autosomal dominant disease characterized by complex and multicellular neurofibroma tumors, and less frequently by malignant peripheral nerve sheath tumors (mpnsts) and optic nerve gliomas. |
2010-02-16 |
2023-08-12 |
Not clear |
| Oren N Gottfried, David H Viskochil, William T Couldwel. Neurofibromatosis Type 1 and tumorigenesis: molecular mechanisms and therapeutic implications. Neurosurgical focus. vol 28. issue 1. 2010-02-16. PMID:20043723. |
importantly, a complex series of interactions with these other cell types in neurofibroma tumorigenesis is mediated by abnormal expression of growth factors and their receptors and modification of gene expression, a key example of which is the process of recruitment and involvement of the nf1(+/-) heterozygous mast cell. |
2010-02-16 |
2023-08-12 |
Not clear |
| Gaetano Magro, Paolo Amico, Giada Maria Vecchio, Rosario Caltabiano, Marine Castaing, Denisa Kacerovska, Dmitry V Kazakov, Michal Micha. Multinucleated floret-like giant cells in sporadic and NF1-associated neurofibromas: a clinicopathologic study of 94 cases. Virchows Archiv : an international journal of pathology. vol 456. issue 1. 2010-02-04. PMID:19937344. |
multinucleated floret-like giant cells (mnfgcs), similar to those commonly observed in pleomorphic lipoma and giant cell fibroblastoma, have been occasionally reported in gynecomastia and neurofibromas from patients affected by neurofibromatosis type 1 (nf1). |
2010-02-04 |
2023-08-12 |
Not clear |