| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marinya Pongpudpunth, Jag Bhawan, Sahar H Al-Natour, Meera Mahalinga. Nestin-positive stem cells in neurofibromas from patients with neurofibromatosis type 1-tumorigenic or incidental? The American Journal of dermatopathology. vol 32. issue 6. 2011-09-27. PMID:20520523. |
recently, we found discrete foci of melanin deposits but diffuse positivity with mart-1/melana in a neurofibroma from a patient with neurofibromatosis type 1 (nf1). |
2011-09-27 |
2023-08-12 |
Not clear |
| Andrew L Ross, Zubin Panthaki, Allan D Lev. Surgical management of a giant plexiform neurofibroma of the lower extremity. World neurosurgery. vol 75. issue 5-6. 2011-08-30. PMID:21704948. |
the authors review their experience with the management of a giant 49-kg (108 lb) neurofibroma of the lower extremity in a 37-year-old male with nf1. |
2011-08-30 |
2023-08-12 |
Not clear |
| Eeva-Mari Jouhilahti, Sirkku Peltonen, Anthony M Heape, Juha Peltone. The pathoetiology of neurofibromatosis 1. The American journal of pathology. vol 178. issue 5. 2011-08-26. PMID:21457932. |
a recent study identified a multipotent precursor cell population with an nf1(+/-) genotype that resides in human cutaneous neurofibromas and that has been suggested to play a role in their pathogenesis. |
2011-08-26 |
2023-08-12 |
human |
| Eric Pasmant, Dominique Vidaud, Marcus Harrison, Meena Upadhyay. Different sized somatic NF1 locus rearrangements in neurofibromatosis 1-associated malignant peripheral nerve sheath tumors. Journal of neuro-oncology. vol 102. issue 3. 2011-07-29. PMID:20686819. |
neurofibromatosis type 1 (nf1) patients are at increased risk of developing both benign (neurofibromas) and malignant (malignant peripheral nerve sheath tumors, mpnst) tumors. |
2011-07-29 |
2023-08-12 |
Not clear |
| Eric Pasmant, Dominique Vidaud, Marcus Harrison, Meena Upadhyay. Different sized somatic NF1 locus rearrangements in neurofibromatosis 1-associated malignant peripheral nerve sheath tumors. Journal of neuro-oncology. vol 102. issue 3. 2011-07-29. PMID:20686819. |
the somatic nf1 inactivation mutational mechanisms associated with mpnsts appear to be different from those in benign neurofibromas. |
2011-07-29 |
2023-08-12 |
Not clear |
| Tracy Tucker, Vincent M Riccardi, Margaret Sutcliffe, Juergen Vielkind, Janine Wechsler, Pierre Wolkenstein, Jan M Friedma. Different patterns of mast cells distinguish diffuse from encapsulated neurofibromas in patients with neurofibromatosis 1. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 59. issue 6. 2011-07-22. PMID:21525187. |
multiple neurofibromas are cardinal features of neurofibromatosis 1 (nf1). |
2011-07-22 |
2023-08-12 |
mouse |
| Tracy Tucker, Vincent M Riccardi, Margaret Sutcliffe, Juergen Vielkind, Janine Wechsler, Pierre Wolkenstein, Jan M Friedma. Different patterns of mast cells distinguish diffuse from encapsulated neurofibromas in patients with neurofibromatosis 1. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 59. issue 6. 2011-07-22. PMID:21525187. |
mast cells are present in most neurofibromas and have been shown to be critical to the origin and progression of neurofibromas in both human nf1 and relevant mouse models. |
2011-07-22 |
2023-08-12 |
mouse |
| B Quintáns, J Pardo, B Campos, F Barros, V Volpini, A Carracedo, M J Sobrid. Neurofibromatosis without Neurofibromas: Confirmation of a Genotype-Phenotype Correlation and Implications for Genetic Testing. Case reports in neurology. vol 3. 2011-07-14. PMID:21532985. |
we confirm the association of the c.2970_2972delaat mutation in nf1 with a particular clinical phenotype, especially with lack of detectable neurofibromas. |
2011-07-14 |
2023-08-12 |
Not clear |
| Hua Li, Xuelian Zhang, Lauren Fishbein, Frederick Kweh, Martha Campbell-Thompson, George Q Perrin, David Muir, Margaret Wallac. Analysis of steroid hormone effects on xenografted human NF1 tumor schwann cells. Cancer biology & therapy. vol 10. issue 8. 2011-06-09. PMID:20699653. |
this suggests that anti-estrogen or anti-progesterone therapies may be worth considering for specific nf1 neurofibromas and mpnsts. |
2011-06-09 |
2023-08-12 |
mouse |
| Eeva-Mari Jouhilahti, Sirkku Peltonen, Tom Callens, Elina Jokinen, Anthony M Heape, Ludwine Messiaen, Juha Peltone. The development of cutaneous neurofibromas. The American journal of pathology. vol 178. issue 2. 2011-05-23. PMID:21281783. |
cutaneous neurofibromas are the hallmarks of neurofibromatosis type 1 (nf1). |
2011-05-23 |
2023-08-12 |
human |
| Eeva-Mari Jouhilahti, Sirkku Peltonen, Tom Callens, Elina Jokinen, Anthony M Heape, Ludwine Messiaen, Juha Peltone. The development of cutaneous neurofibromas. The American journal of pathology. vol 178. issue 2. 2011-05-23. PMID:21281783. |
the results led us to speculate that the development of cutaneous neurofibromas includes the recruitment of multipotent nf1(+/-) precursor cells. |
2011-05-23 |
2023-08-12 |
human |
| Shi Chen, Sarah Burgin, Andrew McDaniel, Xiaohong Li, Jin Yuan, Mia Chen, Waleed Khalaf, D Wade Clapp, Feng-Chun Yan. Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase. The American journal of pathology. vol 177. issue 6. 2011-03-15. PMID:21037083. |
these studies identify the p21(ras)-pi3k pathway as a major regulator of the gain in nf1(+/-) mast cell degranulation in neurofibromas. |
2011-03-15 |
2023-08-12 |
Not clear |
| Jean-Paul Steib, Steib Jean-Paul, Julia Bouchaïb, Bouchaïb Julia, Axel Walter, Walter Axel, Sébastien Schuller, Schuller Sébastien, Yann Philippe Charles, Charles Philipp. Could an osteoinductor result in degeneration of a neurofibroma in NF1? European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 19 Suppl 2. 2011-02-16. PMID:20449613. |
could an osteoinductor result in degeneration of a neurofibroma in nf1? |
2011-02-16 |
2023-08-12 |
Not clear |
| Jean-Paul Steib, Steib Jean-Paul, Julia Bouchaïb, Bouchaïb Julia, Axel Walter, Walter Axel, Sébastien Schuller, Schuller Sébastien, Yann Philippe Charles, Charles Philipp. Could an osteoinductor result in degeneration of a neurofibroma in NF1? European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 19 Suppl 2. 2011-02-16. PMID:20449613. |
nf1 is characterised by neurofibromas that have a possibility of malign degeneration and conversion to a sarcoma. |
2011-02-16 |
2023-08-12 |
Not clear |
| Guolin Chai, Ning Liu, Junrong Ma, Hua Li, Janet L Oblinger, Agasanur K Prahalad, Meng Gong, Long-Sheng Chang, Margaret Wallace, David Muir, Abhijit Guha, Roger J Phipps, Janet M Hock, Xijie Y. MicroRNA-10b regulates tumorigenesis in neurofibromatosis type 1. Cancer science. vol 101. issue 9. 2011-02-09. PMID:20550523. |
we demonstrated that mir-10b was up-regulated in primary schwann cells isolated from nf1 neurofibromas and in cell lines and tumor tissues from malignant peripheral nerve sheath tumors (mpnsts). |
2011-02-09 |
2023-08-12 |
human |
| Reecha Sachdeva, David A Rothner, Elias I Traboulsi, Brandy C Hayden, Paul J Rychwalsk. Astrocytic hamartoma of the optic disc and multiple café-au-lait macules in a child with neurofibromatosis type 2. Ophthalmic genetics. vol 31. issue 4. 2011-01-21. PMID:21067482. |
this patient had been previously diagnosed with nf1 on the basis of multiple cal macules and suspected subcutaneous neurofibromas. |
2011-01-21 |
2023-08-12 |
Not clear |
| Laura Thomas, Lan Kluwe, Nadia Chuzhanova, Victor Mautner, Meena Upadhyay. Analysis of NF1 somatic mutations in cutaneous neurofibromas from patients with high tumor burden. Neurogenetics. vol 11. issue 4. 2011-01-18. PMID:20358387. |
analysis of nf1 somatic mutations in cutaneous neurofibromas from patients with high tumor burden. |
2011-01-18 |
2023-08-12 |
Not clear |
| Laura Thomas, Lan Kluwe, Nadia Chuzhanova, Victor Mautner, Meena Upadhyay. Analysis of NF1 somatic mutations in cutaneous neurofibromas from patients with high tumor burden. Neurogenetics. vol 11. issue 4. 2011-01-18. PMID:20358387. |
we have analyzed the somatic mutations in 89 cutaneous neurofibromas derived from three unrelated nf1 patients with high tumor burden, by loss of heterozygosity (loh) analysis of the nf1, tp53, rb1, and cdkn2a genes, by assessing microsatellite instability (msi), by direct sequencing of the nf1, tp53, and several mismatch repair (mmr) genes and by multiplex ligation-dependent probe amplification of the nf1 and tp53 genes. |
2011-01-18 |
2023-08-12 |
Not clear |
| Laura Thomas, Lan Kluwe, Nadia Chuzhanova, Victor Mautner, Meena Upadhyay. Analysis of NF1 somatic mutations in cutaneous neurofibromas from patients with high tumor burden. Neurogenetics. vol 11. issue 4. 2011-01-18. PMID:20358387. |
somatic nf1 mutations were identified in 57 (64%) of neurofibroma samples. |
2011-01-18 |
2023-08-12 |
Not clear |
| Yoshimi Arima, Hidemi Hayashi, Kanako Kamata, Takaaki M Goto, Mikako Sasaki, Akira Kuramochi, Hideyuki Say. Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1. Experimental dermatology. vol 19. issue 8. 2011-01-06. PMID:20002172. |
plexiform and/or dermal neurofibromas are nerve sheath tumors of the peripheral nervous system that are usually present in individuals with neurofibromatosis type 1 (nf1). |
2011-01-06 |
2023-08-12 |
human |