| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oren N Gottfried, David H Viskochil, Daniel W Fults, William T Couldwel. Molecular, genetic, and cellular pathogenesis of neurofibromas and surgical implications. Neurosurgery. vol 58. issue 1. 2006-05-23. PMID:16385324. |
understanding the biological underpinnings of tumorigenesis in nf1 has implications for future surgical and medical management of neurofibromas. |
2006-05-23 |
2023-08-12 |
Not clear |
| M Geller, M G Ribeiro, A P de Q C Araújo, L J B de Oliveira, F P Nune. Serum IgE levels in neurofibromatosis 1. International journal of immunogenetics. vol 33. issue 2. 2006-05-23. PMID:16611255. |
the purposes of this study were to determine the serum ige levels of patients with nf1 presenting plexiform neurofibromas, neurofibromas and no neurofibromas, as well as to determine possible correlations between serum ige levels and the size of the plexiform neurofibromas and neurofibromas presented by these patients. |
2006-05-23 |
2023-08-12 |
Not clear |
| M Geller, M G Ribeiro, A P de Q C Araújo, L J B de Oliveira, F P Nune. Serum IgE levels in neurofibromatosis 1. International journal of immunogenetics. vol 33. issue 2. 2006-05-23. PMID:16611255. |
we suggest further studies to confirm these results and to investigate in greater depth the possible role of ige in the development and growth of neurofibromas and plexiform neurofibromas in nf1. |
2006-05-23 |
2023-08-12 |
Not clear |
| Zlatko Sabol, Ljiljana Kipke-Sabo. [Neurofibromatosis type 1 (von Recklinghausen's disease or peripheral neurofibromatosis): from phenotype to gene]. Lijecnicki vjesnik. vol 127. issue 11-12. 2006-05-16. PMID:16583938. |
the clinical diagnosis of nf1 is based on the presence of two or more of the following criteria: six or more café au lait spots, >2 neurofibromas of any type or 1 plexiform neurofibroma, freckling in the axillary or inguinal region, optic glioma, a distinctive osseous lesion such as sphenoid dysplasia or thinning of long bone cortex with or without pseudoarthrosis, and a first degree relative with nf1. |
2006-05-16 |
2023-08-12 |
Not clear |
| Masahito Hatori, Masami Hosaka, Mika Watanabe, Takuya Moriya, Hironobu Sasano, Shoichi Kokubu. Osteosarcoma in a patient with neurofibromatosis type 1: a case report and review of the literature. The Tohoku journal of experimental medicine. vol 208. issue 4. 2006-05-09. PMID:16565597. |
neurofibromatosis type 1 (nf1) or von recklinghausen's disease is a genetic disease generally characterized by café-au-lait spots and neurofibromas. |
2006-05-09 |
2023-08-12 |
Not clear |
| Michaela Gstöttner, Oliver Galvan, Andreas Gschwendtner, Andreas Nehe. Solitary subglottic neurofibroma: a report of an unusual manifestation. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 262. issue 9. 2006-05-04. PMID:15947937. |
most of the patients with neurofibromas suffer from neurofibromatosis type 1 (nf1, von recklinghausen's disease), which is characterized by cafe-au-lait spots and neurofibromas of any type. |
2006-05-04 |
2023-08-12 |
Not clear |
| Charles A Powell, Corey M Stanley, Sharon R Bannister, Howard T McDonnell, Alan J Moritz, David E Dea. Palatal neurofibroma associated with localized periodontitis. Journal of periodontology. vol 77. issue 2. 2006-05-04. PMID:16460259. |
in this report, we present the case of a palatal neurofibroma with radiographic involvement in a patient with nf1. |
2006-05-04 |
2023-08-12 |
Not clear |
| Kati P Pummi, Heikki J Aho, Matti K Laato, Juha T K Peltonen, Sirkku A Peltone. Tight junction proteins and perineurial cells in neurofibromas. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 54. issue 1. 2006-03-02. PMID:16087703. |
in this study, tight junctions (tjs) of 16 neurofibromas from 12 patients with neurofibromatosis type 1 (nf1) were analyzed using electron microscopy, immunohistochemistry, and western transfer analysis. |
2006-03-02 |
2023-08-12 |
Not clear |
| Min Wu, Margaret R Wallace, David Mui. Tumorigenic properties of neurofibromin-deficient Schwann cells in culture and as syngrafts in Nf1 knockout mice. Journal of neuroscience research. vol 82. issue 3. 2006-02-24. PMID:16180234. |
functional loss of the nf1 tumor suppressor is frequently associated with the generation of benign neurofibromas that can progress to malignancy. |
2006-02-24 |
2023-08-12 |
mouse |
| Min Wu, Margaret R Wallace, David Mui. Tumorigenic properties of neurofibromin-deficient Schwann cells in culture and as syngrafts in Nf1 knockout mice. Journal of neuroscience research. vol 82. issue 3. 2006-02-24. PMID:16180234. |
recent evidence in genetic mouse models indicates that the development of neurofibromas requires a loss of nf1 in the cells destined to become neoplastic as well as heterozygosity in nonneoplastic cells. |
2006-02-24 |
2023-08-12 |
mouse |
| N Mimoun, N Razzouq, P Wolkenstein, J C Moreno, J P Marty, L Lantieri, A Astier, M Pau. Evaluation of skin viscoelasticity in type 1 neurofibromatosis patients. Skin pharmacology and physiology. vol 19. issue 1. 2006-02-09. PMID:16247246. |
neurofibromatosis type 1 (nf1) is a frequent autosomal dominant disease characterized by cutaneous benign tumors called neurofibromas. |
2006-02-09 |
2023-08-12 |
human |
| N Mimoun, N Razzouq, P Wolkenstein, J C Moreno, J P Marty, L Lantieri, A Astier, M Pau. Evaluation of skin viscoelasticity in type 1 neurofibromatosis patients. Skin pharmacology and physiology. vol 19. issue 1. 2006-02-09. PMID:16247246. |
the extensibility at the first and the fifth traction in nf1 patients (neurofibromas and the supposedly healthy skin around it) was significantly different compared to the healthy skin of control subjects. |
2006-02-09 |
2023-08-12 |
human |
| N Mimoun, N Razzouq, P Wolkenstein, J C Moreno, J P Marty, L Lantieri, A Astier, M Pau. Evaluation of skin viscoelasticity in type 1 neurofibromatosis patients. Skin pharmacology and physiology. vol 19. issue 1. 2006-02-09. PMID:16247246. |
the viscoelastic parameters obtained from the neurofibromas were significantly different in comparison to those obtained from the supposedly healthy skin of nf1 patients and the healthy skin of control subjects. |
2006-02-09 |
2023-08-12 |
human |
| N Mimoun, N Razzouq, P Wolkenstein, J C Moreno, J P Marty, L Lantieri, A Astier, M Pau. Evaluation of skin viscoelasticity in type 1 neurofibromatosis patients. Skin pharmacology and physiology. vol 19. issue 1. 2006-02-09. PMID:16247246. |
the rheological profiles of the neurofibromas and the apparent healthy skin of nf1 patients demonstrated a hyperextensibility behavior, but in neurofibromas, the skin was unable to return to its initial position at the end of the stretch. |
2006-02-09 |
2023-08-12 |
human |
| Tatsuya Ozawa, Norie Araki, Shunji Yunoue, Hiroshi Tokuo, Liping Feng, Siriporn Patrakitkomjorn, Toshihiro Hara, Yasuko Ichikawa, Kunio Matsumoto, Kiyotaka Fujii, Hideyuki Say. The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway. The Journal of biological chemistry. vol 280. issue 47. 2006-02-03. PMID:16169856. |
these findings may explain, in part, the mechanism of multiple neurofibroma formation in nf1 patients. |
2006-02-03 |
2023-08-12 |
Not clear |
| Vasilios Panteris, Thivi Vassilakaki, Nikos Vaitsis, Ioannis Elemenoglou, Irini Mylonakou, Dimitrios-Georgios Karamanoli. Solitary colonic neurofibroma in a patient with transient segmental colitis: case report. World journal of gastroenterology. vol 11. issue 35. 2006-01-25. PMID:16222760. |
neurofibromas of the large bowel are very rare and usually are part of the colonic involvement in neurofibromatosis type 1 (nf1, von recklinghausen's disease). |
2006-01-25 |
2023-08-12 |
Not clear |
| T Tucker, P Wolkenstein, J Revuz, J Zeller, J M Friedma. Association between benign and malignant peripheral nerve sheath tumors in NF1. Neurology. vol 65. issue 2. 2006-01-04. PMID:16043787. |
the authors conducted a study to determine whether people with nf1 who have benign neurofibromas of various kinds are at greater risk of developing mpnsts than patients with nf1 who lack these benign tumors. |
2006-01-04 |
2023-08-12 |
Not clear |
| Clelia Tiziana Storlazzi, Fredrik Vult Von Steyern, Henryk A Domanski, Nils Mandahl, Fredrik Merten. Biallelic somatic inactivation of the NF1 gene through chromosomal translocations in a sporadic neurofibroma. International journal of cancer. vol 117. issue 6. 2005-12-14. PMID:15986446. |
biallelic somatic inactivation of the nf1 gene through chromosomal translocations in a sporadic neurofibroma. |
2005-12-14 |
2023-08-12 |
Not clear |
| Clelia Tiziana Storlazzi, Fredrik Vult Von Steyern, Henryk A Domanski, Nils Mandahl, Fredrik Merten. Biallelic somatic inactivation of the NF1 gene through chromosomal translocations in a sporadic neurofibroma. International journal of cancer. vol 117. issue 6. 2005-12-14. PMID:15986446. |
neurofibroma is a benign tumor originating from schwann cells in peripheral nerve sheaths and may occur as a sporadic tumor or as part of the dominantly inherited tumor syndrome nf1. |
2005-12-14 |
2023-08-12 |
Not clear |
| Clelia Tiziana Storlazzi, Fredrik Vult Von Steyern, Henryk A Domanski, Nils Mandahl, Fredrik Merten. Biallelic somatic inactivation of the NF1 gene through chromosomal translocations in a sporadic neurofibroma. International journal of cancer. vol 117. issue 6. 2005-12-14. PMID:15986446. |
whereas the involvement of the nf1 gene in neurofibroma development in nf1 patients has been fairly well characterized, the significance of inactivation of this gene in sporadic neurofibromas remains less well investigated. |
2005-12-14 |
2023-08-12 |
Not clear |