| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T De Raedt, H Brems, P Wolkenstein, D Vidaud, S Pilotti, F Perrone, V Mautner, S Frahm, R Sciot, E Legiu. Elevated risk for MPNST in NF1 microdeletion patients. American journal of human genetics. vol 72. issue 5. 2003-07-01. PMID:12660952. |
individuals with an nf1 microdeletion have, as a group, more neurofibromas at a younger age than the group of all individuals with nf1. |
2003-07-01 |
2023-08-12 |
Not clear |
| H Endo, A Utani, F Matsumoto, T Kuroki, S Yoshimoto, M Ichinose, H Shinka. A possible paracrine hedgehog signalling pathway in neurofibromas from patients with neurofibromatosis type 1. The British journal of dermatology. vol 148. issue 2. 2003-04-03. PMID:12588389. |
however, there has been no study on the role of hhs and their receptors in tumorigenesis of neurofibromas in neurofibromatosis type 1 (nf1). |
2003-04-03 |
2023-08-12 |
Not clear |
| Tomoe Kotsuji-Maruyama, Sumihisa Imakado, Yasuhiro Kawachi, Fujio Otsuk. PDGF-BB induces MAP kinase phosphorylation and VEGF expression in neurofibroma-derived cultured cells from patients with neurofibromatosis 1. The Journal of dermatology. vol 29. issue 11. 2003-03-18. PMID:12484433. |
neurofibromas of neurofibromatosis 1 (nf1) are highly vascular. |
2003-03-18 |
2023-08-12 |
Not clear |
| Gaetano Magro, Sebastiano Scavo, Martino Ruggier. Floretlike multinucleated giant cells in a neurofibroma from a patient with NF1: an unusual finding for such a tumor. Virchows Archiv : an international journal of pathology. vol 441. issue 5. 2003-01-23. PMID:12516575. |
floretlike multinucleated giant cells in a neurofibroma from a patient with nf1: an unusual finding for such a tumor. |
2003-01-23 |
2023-08-12 |
Not clear |
| Timothy M Lynch, David H Gutman. Neurofibromatosis 1. Neurologic clinics. vol 20. issue 3. 2003-01-07. PMID:12432832. |
individuals with nf1 are predisposed to the development of peripheral nerve sheath tumors (neurofibromas and mpnsts), astrocytomas (optic pathway gliomas), learning disabilities, seizures, strokes, macrocephaly, and vascular abnormalities. |
2003-01-07 |
2023-08-12 |
Not clear |
| Katharina Wimmer, Manfred Mühlbauer, Markus Eckart, Tom Callens, Helga Rehder, Thomas Birkner, Jules G Leroy, Christa Fonatsch, Ludwine Messiae. A patient severely affected by spinal neurofibromas carries a recurrent splice site mutation in the NF1 gene. European journal of human genetics : EJHG. vol 10. issue 5. 2002-12-10. PMID:12082509. |
a patient severely affected by spinal neurofibromas carries a recurrent splice site mutation in the nf1 gene. |
2002-12-10 |
2023-08-12 |
Not clear |
| Katharina Wimmer, Manfred Mühlbauer, Markus Eckart, Tom Callens, Helga Rehder, Thomas Birkner, Jules G Leroy, Christa Fonatsch, Ludwine Messiae. A patient severely affected by spinal neurofibromas carries a recurrent splice site mutation in the NF1 gene. European journal of human genetics : EJHG. vol 10. issue 5. 2002-12-10. PMID:12082509. |
spinal neurofibromas are found in up to 38% of nf1 patients. |
2002-12-10 |
2023-08-12 |
Not clear |
| Katharina Wimmer, Manfred Mühlbauer, Markus Eckart, Tom Callens, Helga Rehder, Thomas Birkner, Jules G Leroy, Christa Fonatsch, Ludwine Messiae. A patient severely affected by spinal neurofibromas carries a recurrent splice site mutation in the NF1 gene. European journal of human genetics : EJHG. vol 10. issue 5. 2002-12-10. PMID:12082509. |
we describe a nf1 patient who satisfies the nih diagnostic criteria and has severe spinal involvement with bilateral spinal root neurofibromas at every level. |
2002-12-10 |
2023-08-12 |
Not clear |
| Margaret E McLaughlin, Tyler Jack. Thinking beyond the tumor cell: Nf1 haploinsufficiency in the tumor environment. Cancer cell. vol 1. issue 5. 2002-09-27. PMID:12124168. |
deletion of both copies of the nf1 gene in schwann cells combined with nf1 heterozygosity in the tumor environment promotes neurofibroma formation in mice. |
2002-09-27 |
2023-08-12 |
mouse |
| Erwin S Schultz, Dieter Kaufmann, Sigrid Tinschert, Hermann Schell, Peter von den Driesch, Gerold Schule. Segmental neurofibromatosis. Dermatology (Basel, Switzerland). vol 204. issue 4. 2002-09-26. PMID:12077526. |
we describe here a patient with segmental nf in which we could not demonstrate any nf1 gene mutation in fibroblasts cultured from neurofibromas by use of the protein truncation test, enzymatic mutation detection and fluorescence in situ hybridisation. |
2002-09-26 |
2023-08-12 |
Not clear |
| Erwin S Schultz, Dieter Kaufmann, Sigrid Tinschert, Hermann Schell, Peter von den Driesch, Gerold Schule. Segmental neurofibromatosis. Dermatology (Basel, Switzerland). vol 204. issue 4. 2002-09-26. PMID:12077526. |
these data are in line with the concept that nf1 mutations in schwann cells, but not in fibroblasts, correlate with neurofibroma formation. |
2002-09-26 |
2023-08-12 |
Not clear |
| Takamasa Koga, Hiroshi Iwasaki, Masako Ishiguro, Akio Matsuzaki, Masahiro Kikuch. Losses in chromosomes 17, 19, and 22q in neurofibromatosis type 1 and sporadic neurofibromas: a comparative genomic hybridization analysis. Cancer genetics and cytogenetics. vol 136. issue 2. 2002-09-24. PMID:12237234. |
in addition, both nf1-associated and sporadic neurofibromas often exhibited losses at chromosome arms 19q and 22q (in nf1 tumors, the minimal common regions were 19q13.2-->qter in seven cases). |
2002-09-24 |
2023-08-12 |
Not clear |
| M Anagnostouli, G Piperingos, C Yapijakis, P Gourtzelidis, S Balafouta, C Zournas, D Vassilopoulos, D Koutras, C Papageorgio. Thyroid gland neurofibroma in a NF1 patient. Acta neurologica Scandinavica. vol 106. issue 1. 2002-08-02. PMID:12067331. |
thyroid gland neurofibroma in a nf1 patient. |
2002-08-02 |
2023-08-12 |
Not clear |
| M Anagnostouli, G Piperingos, C Yapijakis, P Gourtzelidis, S Balafouta, C Zournas, D Vassilopoulos, D Koutras, C Papageorgio. Thyroid gland neurofibroma in a NF1 patient. Acta neurologica Scandinavica. vol 106. issue 1. 2002-08-02. PMID:12067331. |
neurofibromas are a hallmark of neurofibromatosis type 1 (nf1). |
2002-08-02 |
2023-08-12 |
Not clear |
| M Anagnostouli, G Piperingos, C Yapijakis, P Gourtzelidis, S Balafouta, C Zournas, D Vassilopoulos, D Koutras, C Papageorgio. Thyroid gland neurofibroma in a NF1 patient. Acta neurologica Scandinavica. vol 106. issue 1. 2002-08-02. PMID:12067331. |
here, we present a 55-year-old man with typical symptoms of nf1, whose course was complicated by a neurofibroma of the thyroid gland. |
2002-08-02 |
2023-08-12 |
Not clear |
| M Anagnostouli, G Piperingos, C Yapijakis, P Gourtzelidis, S Balafouta, C Zournas, D Vassilopoulos, D Koutras, C Papageorgio. Thyroid gland neurofibroma in a NF1 patient. Acta neurologica Scandinavica. vol 106. issue 1. 2002-08-02. PMID:12067331. |
the rarity of thyroid gland neurofibroma is discussed here, emphasizing the importance of early detection of these and other nf1 complications, also including the risk of malignant transformation with lethal outcome. |
2002-08-02 |
2023-08-12 |
Not clear |
| Michael A Liew, Cheryl M Coffin, Jonathan A Fletcher, Minh-Thu N Hang, Katsumi Tanito, Michihito Niimura, David Viskochi. Peripheral nerve sheath tumors from patients with neurofibromatosis type 1 do not have the chromosomal translocation t(X;18). Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. vol 5. issue 2. 2002-06-20. PMID:11910511. |
the results indicate that the t(x;18) translocation is absent in neurofibromas and is not a marker for mpnst in patients with nf1. |
2002-06-20 |
2023-08-12 |
Not clear |
| R J Packer, D H Gutmann, A Rubenstein, D Viskochil, R A Zimmerman, G Vezina, J Small, B Kor. Plexiform neurofibromas in NF1: toward biologic-based therapy. Neurology. vol 58. issue 10. 2002-06-17. PMID:12041525. |
neurofibromas are one of the most common of the protean manifestations of nf1. |
2002-06-17 |
2023-08-12 |
Not clear |
| Noriko Kimura, Toshiya Watanabe, Masayuki Fukase, Atsushi Wakita, Takao Noshiro, Itaru Kimur. Neurofibromin and NF1 gene analysis in composite pheochromocytoma and tumors associated with von Recklinghausen's disease. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. vol 15. issue 3. 2002-06-11. PMID:11904334. |
neurofibromin was not expressed in schwann cells and sustentacular cells of composite pheochromocytomas and was very weakly or negatively expressed in neurofibroma of nf1 patients. |
2002-06-11 |
2023-08-12 |
Not clear |
| Yuan Zhu, Pritam Ghosh, Patrick Charnay, Dennis K Burns, Luis F Parad. Neurofibromas in NF1: Schwann cell origin and role of tumor environment. Science (New York, N.Y.). vol 296. issue 5569. 2002-05-30. PMID:11988578. |
neurofibromas in nf1: schwann cell origin and role of tumor environment. |
2002-05-30 |
2023-08-12 |
Not clear |