| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chun Tak Kwok, Hsiang-Ya Wang, Alex G Morris, Bradley Smith, Christopher Shaw, Jackie de Belleroch. VCP mutations are not a major cause of familial amyotrophic lateral sclerosis in the UK. Journal of the neurological sciences. vol 349. issue 1-2. 2015-09-28. PMID:25618255. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease causing loss of motor neurons in the spinal cord, brain stem and cerebral cortex. |
2015-09-28 |
2023-08-13 |
Not clear |
| Kwang S Kim, Hong J Lee, Jin An, Yun B Kim, Jung Chan Ra, Inja Lim, Seung U Ki. Transplantation of human adipose tissue-derived stem cells delays clinical onset and prolongs life span in ALS mouse model. Cell transplantation. vol 23. issue 12. 2015-09-15. PMID:24070071. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease that selectively affects motor neurons in the cortex, brain stem, and spinal cord. |
2015-09-15 |
2023-08-12 |
mouse |
| Chan Tian, Di Liu, Wei Xiang, Hans A Kretzschmar, Qing-Lan Sun, Chen Gao, Yin Xu, Hui Wang, Xue-Yu Fan, Ge Meng, Wei Li, Xiao-Ping Don. Analyses of the similarity and difference of global gene expression profiles in cortex regions of three neurodegenerative diseases: sporadic Creutzfeldt-Jakob disease (sCJD), fatal familial insomnia (FFI), and Alzheimer's disease (AD). Molecular neurobiology. vol 50. issue 2. 2015-09-11. PMID:24902808. |
analyses of the similarity and difference of global gene expression profiles in cortex regions of three neurodegenerative diseases: sporadic creutzfeldt-jakob disease (scjd), fatal familial insomnia (ffi), and alzheimer's disease (ad). |
2015-09-11 |
2023-08-13 |
Not clear |
| U E Williams, E E Philip-Ephraim, S K Opara. Multidisciplinary Interventions in Motor Neuron Disease. Journal of neurodegenerative diseases. vol 2014. 2015-08-28. PMID:26317009. |
motor neuron disease is a neurodegenerative disease characterized by loss of upper motor neuron in the motor cortex and lower motor neurons in the brain stem and spinal cord. |
2015-08-28 |
2023-08-13 |
Not clear |
| Belén Ansoleaga, Paula Garcia-Esparcia, Raquel Pinacho, Josep Maria Haro, Belén Ramos, Isidre Ferre. Decrease in olfactory and taste receptor expression in the dorsolateral prefrontal cortex in chronic schizophrenia. Journal of psychiatric research. vol 60. 2015-08-04. PMID:25282281. |
we have recently identified up- or down-regulation of the olfactory (or) and taste (tasr) chemoreceptors in the human cortex in several neurodegenerative diseases, raising the possibility of a general deregulation of these genes in neuropsychiatric disorders. |
2015-08-04 |
2023-08-13 |
human |
| H-Q Jiang, M Ren, H-Z Jiang, J Wang, J Zhang, X Yin, S-Y Wang, Y Qi, X-D Wang, H-L Fen. Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis. Neuroscience. vol 277. 2015-06-08. PMID:24699224. |
amyotrophic lateral sclerosis (als) is a relentlessly progressive neurodegenerative disease characterized by the loss of motor neurons in the motor cortex, brain stem and spinal cord. |
2015-06-08 |
2023-08-13 |
mouse |
| Margherita Grasso, Paola Piscopo, Annamaria Confaloni, Michela A Dent. Circulating miRNAs as biomarkers for neurodegenerative disorders. Molecules (Basel, Switzerland). vol 19. issue 5. 2015-06-01. PMID:24858274. |
all neurodegenerative diseases are characterized by neuronal loss and death in specific areas of the brain, for example, hippocampus and cortex for ad, midbrain for pd, frontal and temporal lobes for ftd. |
2015-06-01 |
2023-08-13 |
Not clear |
| Jun-Ichi Satoh, Naohiro Asahina, Shouta Kitano, Yoshihiro Kin. A Comprehensive Profile of ChIP-Seq-Based Olig2 Target Genes in Motor Neuron Progenitor Cells Suggests the Possible Involvement of Olig2 in the Pathogenesis of Amyotrophic Lateral Sclerosis. Journal of central nervous system disease. vol 7. 2015-05-29. PMID:26023283. |
amyotrophic lateral sclerosis (als) is an intractable neurodegenerative disease that primarily affects motor neurons in the cerebral cortex and the spinal cord. |
2015-05-29 |
2023-08-13 |
Not clear |
| Yuta Yoshino, Mitsue Ishisaka, Saori Tsujii, Masamitsu Shimazawa, Hideaki Har. Glucagon-like peptide-1 protects the murine hippocampus against stressors via Akt and ERK1/2 signaling. Biochemical and biophysical research communications. vol 458. issue 2. 2015-05-01. PMID:25660451. |
alzheimer's disease (ad) is a common neurodegenerative disease characterized by cognitive dysfunction and neuronal cell death in the hippocampus and cerebral cortex. |
2015-05-01 |
2023-08-13 |
mouse |
| Hans-Georg König, Karen S Coughlan, Sinéad Kinsella, Bridget A Breen, Jochen H M Preh. The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes. Neurobiology of disease. vol 70. 2015-04-21. PMID:24956542. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the loss of motoneurons in the spinal cord, brainstem and motor cortex. |
2015-04-21 |
2023-08-13 |
mouse |
| Vanessa Cavalcante da Silva, Leandro Fernandes, Eduardo Jun Haseyama, Ana Luiza Dias Abdo Agamme, Elvira Maria Guerra Shinohara, Maria Tereza Cartaxo Muniz, Vânia D'Almeid. Effect of vitamin B deprivation during pregnancy and lactation on homocysteine metabolism and related metabolites in brain and plasma of mice offspring. PloS one. vol 9. issue 4. 2015-02-10. PMID:24695104. |
the decreased plasma gsh concentration may reflect redox changes in tissues and the decreased brain cortex sam may be involved in changes of gene expression, which could contribute to neurodegenerative diseases over the long term. |
2015-02-10 |
2023-08-13 |
mouse |
| Renzo Mancuso, Jaume del Valle, Laura Modol, Anna Martinez, Ana B Granado-Serrano, Omar Ramirez-Núñez, Mercé Pallás, Manel Portero-Otin, Rosario Osta, Xavier Navarr. Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 11. issue 2. 2014-12-16. PMID:24414863. |
amyotrophic lateral sclerosis (als) is an adult onset neurodegenerative disease that causes progressive paralysis and death due to degeneration of motoneurons in spinal cord, brainstem and motor cortex. |
2014-12-16 |
2023-08-12 |
mouse |
| Anthony Conway, David V Schaffe. Biomaterial microenvironments to support the generation of new neurons in the adult brain. Stem cells (Dayton, Ohio). vol 32. issue 5. 2014-12-15. PMID:24449485. |
we thus demonstrate for the first time de novo neurogenesis in both the cortex and striatum of adult rodents stimulated solely by delivery of synthetic biomaterial forms of proteins naturally found within adult neurogenic niches, offering the potential to replace neurons lost in neurodegenerative disease or injury as an alternative to cell implantation. |
2014-12-15 |
2023-08-12 |
Not clear |
| Renzo Mancuso, Jaume Del Valle, Marta Morell, Mercé Pallás, Rosario Osta, Xavier Navarr. Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G⁹³A ALS mice: overlapping effects or limited therapeutic opportunity? Orphanet journal of rare diseases. vol 9. 2014-11-12. PMID:24885036. |
amyotrophic lateral sclerosis (als) is an adult onset neurodegenerative disease characterized by the loss of motoneurons (mns) in the spinal cord, brainstem and motor cortex, causing progressive paralysis and death. |
2014-11-12 |
2023-08-13 |
mouse |
| Alissa L Nana, Eric H Kim, Doris C V Thu, Dorothy E Oorschot, Lynette J Tippett, Virginia M Hogg, Beth J Synek, Richard Roxburgh, Henry J Waldvogel, Richard L M Faul. Widespread heterogeneous neuronal loss across the cerebral cortex in Huntington's disease. Journal of Huntington's disease. vol 3. issue 1. 2014-10-27. PMID:25062764. |
huntington's disease is an autosomal dominant neurodegenerative disease characterized by neuronal degeneration in the basal ganglia and cerebral cortex, and a variable symptom profile. |
2014-10-27 |
2023-08-13 |
Not clear |
| Xiao-Mo Chen, Zhi-Mei Qiao, Shang-Kai Gao, Bo Hon. [In vivo extracellular neural recording for the study of cortical plasticity]. Sheng li xue bao : [Acta physiologica Sinica]. vol 59. issue 6. 2014-09-26. PMID:18157481. |
measurement of the plasticity of cortex can help understand the mechanism of plasticity, and provide a quantitative way to observe the neural process of natural aging and neurodegenerative diseases, which may lead to a new approach for evaluation of anti-aging drugs and new medical treatments for neurodegenerative diseases. |
2014-09-26 |
2023-08-12 |
rat |
| M Dhruba Singh, Kritika Raj, Surajit Sarka. Drosophila Myc, a novel modifier suppresses the poly(Q) toxicity by modulating the level of CREB binding protein and histone acetylation. Neurobiology of disease. vol 63. 2014-09-19. PMID:24291519. |
polyglutamine or poly(q) disorders are dominantly inherited neurodegenerative diseases characterised by progressive loss of neurons in cerebellum, basal ganglia and cortex in adult human brain. |
2014-09-19 |
2023-08-12 |
human |
| Xue-Qin Hou, Rong Yan, Cong Yang, Lei Zhang, Ru-Yu Su, Si-Jun Liu, Shi-Jie Zhang, Wen-Qing He, Shu-Huan Fang, Shu-Yi Cheng, Zi-Ren Su, Yun-Bo Chen, Qi Wan. A novel assay for high-throughput screening of anti-Alzheimer's disease drugs to determine their efficacy by real-time monitoring of changes in PC12 cell proliferation. International journal of molecular medicine. vol 33. issue 3. 2014-09-09. PMID:24378397. |
alzheimer's disease (ad) is a neurodegenerative disease that is characterized by the accumulation of senile plaque and neurofibrilary tangle formation in the brain, including the cerebral cortex and hippocampus. |
2014-09-09 |
2023-08-12 |
Not clear |
| Masakazu Miyajima, Madoka Nakajima, Yumiko Motoi, Masao Moriya, Hidenori Sugano, Ikuko Ogino, Eri Nakamura, Norihiro Tada, Miyuki Kunichika, Hajime Ara. Leucine-rich α2-glycoprotein is a novel biomarker of neurodegenerative disease in human cerebrospinal fluid and causes neurodegeneration in mouse cerebral cortex. PloS one. vol 8. issue 9. 2014-06-16. PMID:24058569. |
leucine-rich α2-glycoprotein is a novel biomarker of neurodegenerative disease in human cerebrospinal fluid and causes neurodegeneration in mouse cerebral cortex. |
2014-06-16 |
2023-08-12 |
mouse |
| Irene G Salado, Miriam Redondo, Murilo L Bello, Concepción Perez, Nicole F Liachko, Brian C Kraemer, Laetitia Miguel, Magalie Lecourtois, Carmen Gil, Ana Martinez, Daniel I Pere. Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. Journal of medicinal chemistry. vol 57. issue 6. 2014-05-27. PMID:24592867. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease where motor neurons in cortex, brain stem, and spinal cord die progressively, resulting in muscle wasting, paralysis, and death. |
2014-05-27 |
2023-08-12 |
drosophila_melanogaster |