| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christine C Guo, Rachel Tan, John R Hodges, Xintao Hu, Saber Sami, Michael Hornberge. Network-selective vulnerability of the human cerebellum to Alzheimer's disease and frontotemporal dementia. Brain : a journal of neurology. vol 139. issue Pt 5. 2017-05-08. PMID:26912642. |
see schmahmann doi101093/brain/aww064 for a scientific commentary on this article: neurodegenerative diseases are associated with distinct and distributed patterns of atrophy in the cerebral cortex. |
2017-05-08 |
2023-08-13 |
human |
| Christine C Guo, Rachel Tan, John R Hodges, Xintao Hu, Saber Sami, Michael Hornberge. Network-selective vulnerability of the human cerebellum to Alzheimer's disease and frontotemporal dementia. Brain : a journal of neurology. vol 139. issue Pt 5. 2017-05-08. PMID:26912642. |
an intriguing yet untested possibility is that the cerebellar circuits, which share extensive connections with the cerebral cortex, could be selectively targeted by major neurodegenerative diseases. |
2017-05-08 |
2023-08-13 |
human |
| Michael Costa, Jamile Bernardi, Tiago Fiuza, Lidiane Costa, Ricardo Brandão, Maria E Pereir. N-acetylcysteine protects memory decline induced by streptozotocin in mice. Chemico-biological interactions. vol 253. 2017-01-30. PMID:27087133. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by cognitive impairment, associated with a reduced concentration of acetylcholine (ach) in brain cortex and hippocampus. |
2017-01-30 |
2023-08-13 |
mouse |
| Qin Yang, Zhi-bao Gu. Polymorphisms in protein disulfide isomerase are associated with sporadic amyotrophic lateral sclerosis in the Chinese Han population. The International journal of neuroscience. vol 126. issue 7. 2017-01-17. PMID:26000911. |
amyotrophic lateral sclerosis (als) is a fatal adult-onset neurodegenerative disease that targets the motor system; it is caused by the loss of motor neurons in the spinal cord, brain stem, and cerebral cortex. |
2017-01-17 |
2023-08-13 |
human |
| Kedar N Prasad, Stephen C Bond. Inhibition of Early Biochemical Defects in Prodromal Huntington's Disease by Simultaneous Activation of Nrf2 and Elevation of Multiple Micronutrients. Current aging science. vol 9. issue 1. 2016-12-13. PMID:26601664. |
huntington's disease (hd) is a progressive fatal dominant hereditary neurodegenerative disease of the brain, which primarily affects the cortex and the striatum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Yan-Qiu Cui, Qi Wang, Dong-Mei Zhang, Jun-Ya Wang, Bing Xiao, Yan Zheng, Xiao-Min Wan. Triptolide Rescues Spatial Memory Deficits and Amyloid-β Aggregation Accompanied by Inhibition of Inflammatory Responses and MAPKs Activity in APP/PS1 Transgenic Mice. Current Alzheimer research. vol 13. issue 3. 2016-12-13. PMID:26906357. |
alzheimer's disease (ad) is the most prevalent neurodegenerative disease characterized by aggregation of amyloid-β (aβ) peptide in the hippocampus and cortex of brain. |
2016-12-13 |
2023-08-13 |
mouse |
| Mehran Nikan, Maire F Osborn, Andrew H Coles, Bruno Mdc Godinho, Lauren M Hall, Reka A Haraszti, Matthew R Hassler, Dimas Echeverria, Neil Aronin, Anastasia Khvorov. Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain. Molecular therapy. Nucleic acids. vol 5. issue 8. 2016-08-10. PMID:27504598. |
the use of sirna-based therapies for the treatment of neurodegenerative disease requires efficient, nontoxic distribution to the affected brain parenchyma, notably the striatum and cortex. |
2016-08-10 |
2023-08-13 |
mouse |
| Jin Wang, Ying Jing, Lili Song, Ying Xin. Neuroprotective effects of Wnt/β-catenin signaling pathway against Aβ -induced tau protein over-phosphorylation in PC12 cells. Biochemical and biophysical research communications. vol 471. issue 4. 2016-08-04. PMID:26809093. |
alzheimer's disease (ad) is a progressive neurodegenerative disease, which is characterized by deposition of senile plaque (sp) and appearance of neurofibrillary tangles (nft) in the cerebral cortex and hippocampus. |
2016-08-04 |
2023-08-13 |
Not clear |
| Darius Saberi, Bastian Ott, Carolin Dahlke, Veronika Matschke, Thomas Schmitt-John, Carsten Theis. The Spatiotemporal Pattern of Degeneration in the Cerebellum of the Wobbler Mouse. Journal of neuropathology and experimental neurology. vol 75. issue 4. 2016-07-21. PMID:26945034. |
amyotrophic lateral sclerosis (als) is a common neurodegenerative disease that affects motor neurons in the spinal cord and motor cortex. |
2016-07-21 |
2023-08-13 |
mouse |
| Grant L Iverson, Andrew J Gardner, Paul McCrory, Ross Zafonte, Rudy J Castellan. A critical review of chronic traumatic encephalopathy. Neuroscience and biobehavioral reviews. vol 56. 2016-06-02. PMID:26183075. |
chronic traumatic encephalopathy (cte) has been described in the literature as a neurodegenerative disease with: (i) localized neuronal and glial accumulations of phosphorylated tau (p-tau) involving perivascular areas of the cerebral cortex, sulcal depths, and with a preference for neurons within superficial cortical laminae; (ii) multifocal axonal varicosities and axonal loss involving deep cortex and subcortical white matter; (iii) relative absence of beta-amyloid deposits; (iv) tdp-43 immunoreactive inclusions and neurites; and (v) broad and diverse clinical features. |
2016-06-02 |
2023-08-13 |
Not clear |
| Sunny Nigam, Masanori Shimono, Shinya Ito, Fang-Chin Yeh, Nicholas Timme, Maxym Myroshnychenko, Christopher C Lapish, Zachary Tosi, Pawel Hottowy, Wesley C Smith, Sotiris C Masmanidis, Alan M Litke, Olaf Sporns, John M Begg. Rich-Club Organization in Effective Connectivity among Cortical Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 3. 2016-05-27. PMID:26791200. |
therefore, this work may help in understanding how the cortex processes information and responds to neurodegenerative diseases. |
2016-05-27 |
2023-08-13 |
mouse |
| Clair A Booth, Thomas Ridler, Tracey K Murray, Mark A Ward, Emily de Groot, Marc Goodfellow, Keith G Phillips, Andrew D Randall, Jonathan T Brow. Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 2. 2016-05-17. PMID:26758825. |
the entorhinal cortex (ec) is one of the first areas to be disrupted in neurodegenerative diseases such as alzheimer's disease and frontotemporal dementia. |
2016-05-17 |
2023-08-13 |
mouse |
| M Ortner, A Kur. [Posterior cortical atrophy. Pathology, diagnosis and treatment of a rare form of dementia]. Der Nervenarzt. vol 86. issue 7. 2016-04-05. PMID:25791802. |
the syndrome of posterior cortical atrophy (pca) is a rare clinical manifestation of several neurodegenerative diseases which affect the parieto-occipital cortex. |
2016-04-05 |
2023-08-13 |
Not clear |
| Akiva N Rappaport, Eyal Jacob, Vijendra Sharma, Sharon Inberg, Alina Elkobi, Hadile Ounallah-Saad, Metsada Pasmanik-Chor, Efrat Edry, Kobi Rosenblu. Expression of Quinone Reductase-2 in the Cortex Is a Muscarinic Acetylcholine Receptor-Dependent Memory Consolidation Constraint. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 47. 2016-03-14. PMID:26609153. |
it is suggested that qr2 expression in the cortex is a removable limiting factor of memory formation and thus serves as a new target to enhance cognitive function and delay the onset of neurodegenerative diseases. |
2016-03-14 |
2023-08-13 |
rat |
| Stefania Marcuzzo, Silvia Bonanno, Dimos Kapetis, Claudia Barzago, Paola Cavalcante, Sara D'Alessandro, Renato Mantegazza, Pia Bernascon. Up-regulation of neural and cell cycle-related microRNAs in brain of amyotrophic lateral sclerosis mice at late disease stage. Molecular brain. vol 8. 2016-01-19. PMID:25626686. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by selective motor neuron degeneration in motor cortex, brainstem and spinal cord. |
2016-01-19 |
2023-08-13 |
mouse |
| Anna Gajowiak, Agnieszka Styś, Rafał R Starzyński, Aleksandra Bednarz, Małgorzata Lenartowicz, Robert Staroń, Paweł Lipińsk. Mice Overexpressing Both Non-Mutated Human SOD1 and Mutated SOD1(G93A) Genes: A Competent Experimental Model for Studying Iron Metabolism in Amyotrophic Lateral Sclerosis. Frontiers in molecular neuroscience. vol 8. 2016-01-18. PMID:26778957. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by degeneration and loss of motor neurons in the spinal cord, brainstem and motor cortex. |
2016-01-18 |
2023-08-13 |
mouse |
| Sara Capoccia, Federica Maccarinelli, Barbara Buffoli, Luigi F Rodella, Ottavio Cremona, Paolo Arosio, Francesca Cirull. Behavioral characterization of mouse models of neuroferritinopathy. PloS one. vol 10. issue 2. 2016-01-08. PMID:25689865. |
nucleotide insertions in the last exon of the ferritin light chain cause a neurodegenerative disease known as neuroferritinopathy, characterized by iron deposition in the brain, particularly in the cerebellum, basal ganglia and motor cortex. |
2016-01-08 |
2023-08-13 |
mouse |
| Nikolett Lénárt, Fruzsina R Walter, Alexandra Bocsik, Petra Sántha, Melinda E Tóth, András Harazin, Andrea E Tóth, Csaba Vizler, Zsolt Török, Ana-Maria Pilbat, László Vígh, László G Puskás, Miklós Sántha, Mária A Del. Cultured cells of the blood-brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment. Fluids and barriers of the CNS. vol 12. 2016-01-05. PMID:26184769. |
latest findings suggest the importance of apob-100 in the development of neurodegenerative diseases and microvascular/perivascular localization of apob-100 protein was demonstrated in the cerebral cortex of apob-100 transgenic mice. |
2016-01-05 |
2023-08-13 |
mouse |
| b' Katarina Vrabec, Bla\\xc5\\xbe Koritnik, Lea Leonardis, Leja Dolenc-Gro\\xc5\\xa1elj, Janez Zidar, Bradley Smith, Caroline Vance, Christopher Shaw, Boris Rogelj, Damjan Glava\\xc4\\x8d, Metka Ravnik-Glava\\xc4\\x8. Genetic analysis of amyotrophic lateral sclerosis in the Slovenian population. Neurobiology of aging. vol 36. issue 3. 2015-11-24. PMID:25585530.' |
amyotrophic lateral sclerosis (als) is a complex fatal neurodegenerative disease characterized by progressive degeneration and loss of upper motor neurons in the cerebral cortex and lower motor neurons in brainstem and spinal cord. |
2015-11-24 |
2023-08-13 |
Not clear |
| Safa Al-Sarraj, Andrew King, Matt Cleveland, Pierre-François Pradat, Andrea Corse, Jeffrey D Rothstein, Peter Nigel Leigh, Bams Abila, Stewart Bates, Jens Wurthner, Vincent Meininge. Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study. Acta neuropathologica communications. vol 2. 2015-10-26. PMID:25510661. |
amyotrophic lateral sclerosis (als) is a primary progressive neurodegenerative disease characterised by neuronal loss of lower motor neurons (in the spinal cord and brainstem) and/or upper motor neurons (in the motor cortex) and subsequent denervation atrophy of skeletal muscle. |
2015-10-26 |
2023-08-13 |
Not clear |