| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter McColgan, Julie Joubert, Sarah J Tabrizi, Geraint Ree. The human motor cortex microcircuit: insights for neurodegenerative disease. Nature reviews. Neuroscience. vol 21. issue 8. 2020-12-04. PMID:32555340. |
in this review, we use a layer-specific and cell-specific approach to integrate physiological accounts of this motor cortex microcircuit with the pathophysiology of neurodegenerative diseases affecting motor functions. |
2020-12-04 |
2023-08-13 |
human |
| A V Alessenko, U A Gutner, V O Nebogatikov, M A Shupik, A A Ustyugo. [The role of lipids in the pathogenesis of lateral amyotrophic sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 120. issue 10. 2020-11-30. PMID:33244966. |
amyotrophic lateral sclerosis (als) is an incurable neurodegenerative disease characterized by selective degeneration of motor neurons of the motor cortex, brain stem and brain stem. |
2020-11-30 |
2023-08-13 |
Not clear |
| Liyu Chen, Clare Watson, Marco Morsch, Nicholas J Cole, Roger S Chung, Darren N Saunders, Justin J Yerbury, Kara L Vin. Improving the Delivery of SOD1 Antisense Oligonucleotides to Motor Neurons Using Calcium Phosphate-Lipid Nanoparticles. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28912673. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease affecting the upper and lower motor neurons in the motor cortex and spinal cord. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rebecca F D'Cruz, Patrick B Murphy, Georgios Kaltsaka. Sleep disordered breathing in motor neurone disease. Journal of thoracic disease. vol 10. issue Suppl 1. 2020-10-01. PMID:29445532. |
motor neurone disease (mnd) is a neurodegenerative disease defined by axonal loss and gliosis of upper and lower motor neurones in the motor cortex, lower brainstem nuclei and ventral horn of the spinal cord. |
2020-10-01 |
2023-08-13 |
Not clear |
| Luke McAlary, J Andrew Aquilina, Justin J Yerbur. Susceptibility of Mutant SOD1 to Form a Destabilized Monomer Predicts Cellular Aggregation and Toxicity but Not Frontiers in neuroscience. vol 10. 2020-09-30. PMID:27867347. |
susceptibility of mutant sod1 to form a destabilized monomer predicts cellular aggregation and toxicity but not amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the rapid and progressive degeneration of upper and lower motor neurons in the spinal cord, brain stem and motor cortex. |
2020-09-30 |
2023-08-13 |
Not clear |
| Roberta Bonafede, Raffaella Mariott. ALS Pathogenesis and Therapeutic Approaches: The Role of Mesenchymal Stem Cells and Extracellular Vesicles. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28377696. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by progressive muscle paralysis determined by the degeneration of motoneurons in the motor cortex brainstem and spinal cord. |
2020-09-30 |
2023-08-13 |
Not clear |
| Franziska Albrecht, Sandrine Bisenius, Rodrigo Morales Schaack, Jane Neumann, Matthias L Schroete. Disentangling the neural correlates of corticobasal syndrome and corticobasal degeneration with systematic and quantitative ALE meta-analyses. NPJ Parkinson's disease. vol 3. 2020-09-30. PMID:28649612. |
remarkably, atrophy in the premotor area/supplementary motor area and posterior midcingulate/frontomedian cortex seems to be specific for corticobasal syndrome/corticobasal degeneration, whereas atrophy in the thalamus and the left posterior superior and middle frontal gyrus/precentral gyrus are also associated with other neurodegenerative diseases according to anatomic likelihood estimation method meta-analyses. |
2020-09-30 |
2023-08-13 |
Not clear |
| Gabriela Delevati Colpo, Erin Furr Stimming, Natalia Pessoa Rocha, Antonio Lucio Teixeir. Promises and pitfalls of immune-based strategies for Huntington's disease. Neural regeneration research. vol 12. issue 9. 2020-09-30. PMID:29089980. |
huntington's disease (hd) is an autosomal-dominant neurodegenerative disease characterized by the selective loss of neurons in the striatum and cortex, leading to progressive motor dysfunction, cognitive decline and behavioral symptoms. |
2020-09-30 |
2023-08-13 |
Not clear |
| Rossana Sirabella, Valeria Valsecchi, Serenella Anzilotti, Ornella Cuomo, Antonio Vinciguerra, Pasquale Cepparulo, Paola Brancaccio, Natascia Guida, Nicolas Blondeau, Lorella M T Canzoniero, Cristina Franco, Salvatore Amoroso, Lucio Annunziato, Giuseppe Pignatar. Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30131665. |
amyotrophic lateral sclerosis (als) is one of the most threatening neurodegenerative disease since it causes muscular paralysis for the loss of motor neurons in the spinal cord, brainstem and motor cortex. |
2020-09-30 |
2023-08-13 |
Not clear |
| Mudan Cai, Eun Jin Yan. Complementary and alternative medicine for treating amyotrophic lateral sclerosis: A narrative review. Integrative medicine research. vol 8. issue 4. 2020-09-29. PMID:31692669. |
amyotrophic lateral sclerosis (als) is a rare neurodegenerative disease that is characterized by selective motor neuron cell death in the motor cortex, brainstem, and spinal cord. |
2020-09-29 |
2023-08-13 |
Not clear |
| Sandra Carrera-Juliá, Mari Luz Moreno, Carlos Barrios, Jose Enrique de la Rubia Ortí, Eraci Drehme. Antioxidant Alternatives in the Treatment of Amyotrophic Lateral Sclerosis: A Comprehensive Review. Frontiers in physiology. vol 11. 2020-09-28. PMID:32116773. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease that produces a selective loss of the motor neurons of the spinal cord, brain stem and motor cortex. |
2020-09-28 |
2023-08-13 |
Not clear |
| Ramya Ranganathan, Shaila Haque, Kayesha Coley, Stephanie Shepheard, Johnathan Cooper-Knock, Janine Kirb. Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32733193. |
amyotrophic lateral sclerosis and frontotemporal dementia are two progressive, adult onset neurodegenerative diseases, caused by the cell death of motor neurons in the motor cortex and spinal cord and cortical neurons in the frontal and temporal lobes, respectively. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xiaojie Zhang, Kang Yang, Weidong L. Autophagy and Motor Neuron Diseases. Advances in experimental medicine and biology. vol 1207. 2020-09-07. PMID:32671738. |
motor neuron diseases (mnd) are a group of fatal progressive neurodegenerative diseases, which selectively affect the motor system in the anterior horn of spinal cord, brainstem, cortex and pyramidal tract. |
2020-09-07 |
2023-08-13 |
Not clear |
| Antoine Bourrier, Polina Shkorbatova, Marco Bonizzato, Elodie Rey, Quentin Barraud, Gregoire Courtine, Riadh Othmen, Valerie Reita, Vincent Bouchiat, Cécile Delacou. Monolayer Graphene Coating of Intracortical Probes for Long-Lasting Neural Activity Monitoring. Advanced healthcare materials. vol 8. issue 18. 2020-08-27. PMID:31402600. |
in particular, such quantitative and long-lasting recordings of individual neurons are crucial during a long time period (several months) to restore essential functions of the cortex, disrupted after injuries, stroke, or neurodegenerative diseases. |
2020-08-27 |
2023-08-13 |
Not clear |
| Frederic Sampedro, Saul Martínez-Horta, Juan Marín-Lahoz, Javier Pagonabarraga, Jaime Kulisevsk. Longitudinal intracortical diffusivity changes in de-novo Parkinson's disease: A promising imaging biomarker. Parkinsonism & related disorders. vol 68. 2020-08-26. PMID:31621613. |
recently, an increase in mean diffusivity (md) within the cerebral cortex has been proposed as a highly sensitive imaging indicator of early microstructural cortical damage in neurodegenerative diseases. |
2020-08-26 |
2023-08-13 |
Not clear |
| Laura Rué, Patrick Oeckl, Mieke Timmers, Annette Lenaerts, Jasmijn van der Vos, Silke Smolders, Lindsay Poppe, Antina de Boer, Ludo Van Den Bosch, Philip Van Damme, Jochen H Weishaupt, Albert C Ludolph, Markus Otto, Wim Robberecht, Robin Lemmen. Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis. Acta neuropathologica communications. vol 7. issue 1. 2020-07-30. PMID:31300041. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease that affects motor neurons in the brainstem, spinal cord and motor cortex. |
2020-07-30 |
2023-08-13 |
mouse |
| Gitika Batra, Manav Jain, Rahul Soloman Singh, Amit Raj Sharma, Ashutosh Singh, Ajay Prakash, Bikash Medh. Novel therapeutic targets for amyotrophic lateral sclerosis. Indian journal of pharmacology. vol 51. issue 6. 2020-06-03. PMID:32029967. |
amyotrophic lateral sclerosis (als) is an untreatable and fatal neurodegenerative disease that is identified by the loss of motor neurons in the spinal cord, brain stem, and motor cortex which theatrically reduces life expectancy. |
2020-06-03 |
2023-08-13 |
Not clear |
| Hon Wai Benjamin Cheng, Wai Tsan Tracy Chen, Chun Kwok Angus Chu, Savio Lee, Joo Shium Lee, Yeuk Fai Hong, Yuen Kwan Judy Chun. The development of neurology palliative care service for motor neuron disease (MND) patients: Hong Kong experience. Annals of palliative medicine. 2019-11-20. PMID:29156906. |
motor neuron disease (mnd) is a neurodegenerative disease characterized by loss of motor neurons in the spinal cord, brainstem and motor cortex. |
2019-11-20 |
2023-08-13 |
Not clear |
| Yuan Chao Xue, Chelsea M Ruller, Gabriel Fung, Yasir Mohamud, Haoyu Deng, Huitao Liu, Jingchun Zhang, Ralph Feuer, Honglin Lu. Enteroviral Infection Leads to Transactive Response DNA-Binding Protein 43 Pathology in Vivo. The American journal of pathology. vol 188. issue 12. 2019-08-20. PMID:30273599. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease that primarily affects motor neurons in the cerebral cortex, brainstem, and spinal cord, leading to progressive paralysis and eventual death. |
2019-08-20 |
2023-08-13 |
mouse |
| Jennifer M Coughlin, Stephanie Slania, Yong Du, Hailey B Rosenthal, Wojciech G Lesniak, Il Minn, Gwenn S Smith, Robert F Dannals, Hiroto Kuwabara, Dean F Wong, Yuchuan Wang, Andrew G Horti, Martin G Pompe. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 59. issue 10. 2019-07-08. PMID:29496987. |
reduced density of the α4β2 nicotinic acetylcholine receptor (α4β2-nachr) in the cortex and hippocampus of the human brain has been reported in aging and patients with neurodegenerative disease. |
2019-07-08 |
2023-08-13 |
human |