| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Timothy Morello, Richard Kollmar, Mark Stewart, Rena Orma. The retrosplenial cortex of Carollia perspicillata, Seba's short-tailed fruit bat. Hippocampus. 2022-08-26. PMID:36018284. |
retrosplenial cortex (rsc) is a brain region involved in critical cognitive functions including memory, planning, and spatial navigation and is commonly affected in neurodegenerative diseases. |
2022-08-26 |
2023-08-14 |
Not clear |
| Qianqian Zhang, Huihui Zhao, Maotao Luo, Xi Cheng, Yanan Li, Qingyang Li, Zheng Wang, Qi Ni. The Classification and Prediction of Ferroptosis-Related Genes in ALS: A Pilot Study. Frontiers in genetics. vol 13. 2022-07-25. PMID:35873477. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by progressive muscle paralysis, which is followed by degeneration of motor neurons in the motor cortex of the brainstem and spinal cord. |
2022-07-25 |
2023-08-14 |
Not clear |
| Van N Huynh, Sheng Wang, Xiaosen Ouyang, Willayat Y Wani, Michelle S Johnson, Balu K Chacko, Anil G Jegga, Wei-Jun Qian, John C Chatham, Victor M Darley-Usmar, Jianhua Zhan. Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases. Frontiers in aging. vol 2. 2022-07-13. PMID:35822049. |
defining the dynamic regulation of o-glcnac proteome in the mouse cortex---the o-glcnacylation of synaptic and trafficking proteins related to neurodegenerative diseases. |
2022-07-13 |
2023-08-14 |
mouse |
| Gabriela Bortolança Chiarotto, Luciana Politti Cartarozzi, Matheus Perez, Ana Laura Midori Rossi Tomiyama, Mateus Vidigal de Castro, Adriana S S Duarte, Ângela Cristina Malheiros Luzo, Alexandre Leite Rodrigues de Oliveir. Delayed onset, immunomodulation, and lifespan improvement of SOD1 Brain research bulletin. 2022-06-19. PMID:35718222. |
delayed onset, immunomodulation, and lifespan improvement of sod1 amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective and progressive loss of motor neurons from the spinal cord, brain stem, and motor cortex. |
2022-06-19 |
2023-08-14 |
human |
| Yurii V Stepanov, Iuliia Golovynska, Renlong Zhang, Sergii Golovynskyi, Liudmyla I Stepanova, Oleksandr Gorbach, Taisa Dovbynchuk, Liudmyla V Garmanchuk, Tymish Y Ohulchanskyy, Junle Q. Near-infrared light reduces β-amyloid-stimulated microglial toxicity and enhances survival of neurons: mechanisms of light therapy for Alzheimer's disease. Alzheimer's research & therapy. vol 14. issue 1. 2022-06-18. PMID:35717405. |
low-intensity light can decelerate neurodegenerative disease progression and reduce amyloid β (aβ) levels in the cortex, though the cellular and molecular mechanisms by which photobiomodulation (pbm) protects against neurodegeneration are still in the early stages. |
2022-06-18 |
2023-08-14 |
Not clear |
| Md Ataur Rahman, M D Hasanur Rahman, A N M Mamun-Or-Rashid, Hongik Hwang, Sooyoung Chung, Bonglee Kim, Hyewhon Rhi. Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer's Disease. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625764. |
alzheimer's disease (ad) is one of the most prevailing neurodegenerative diseases in the world, which is characterized by memory dysfunction and the formation of tau and amyloid β (aβ) aggregates in multiple brain regions, including the hippocampus and cortex. |
2022-05-28 |
2023-08-13 |
Not clear |
| Seung-Eun Lee, Hanul Choi, Nari Shin, Dasom Kong, Nam Gyo Kim, Hee-Yeong Kim, Min-Ji Kim, Soon Won Choi, Young Bong Kim, Kyung-Sun Kan. Zika virus infection accelerates Alzheimer's disease phenotypes in brain organoids. Cell death discovery. vol 8. issue 1. 2022-04-03. PMID:35368019. |
alzheimer's disease (ad) is one of the progressive neurodegenerative diseases characterized by β-amyloid (aβ) production and phosphorylated-tau (p-tau) protein in the cerebral cortex. |
2022-04-03 |
2023-08-13 |
Not clear |
| Leonardo Provetti Cunha, Leopoldo Antônio Pires, Marcelo Maroco Cruzeiro, Ana Laura Maciel Almeida, Luiza Cunha Martins, Pedro Nascimento Martins, Nadia Shigaeff, Thiago Cardoso Val. Optical coherence tomography in neurodegenerative disorders. Arquivos de neuro-psiquiatria. vol 80. issue 2. 2022-03-30. PMID:35352756. |
the retina shares embryological, histological, biochemical, microvascular and neurotransmitter similarities with the cerebral cortex, thus making it a uniquely promising biomarker for neurodegenerative diseases. |
2022-03-30 |
2023-08-13 |
Not clear |
| Aditi Sharma, Tapan Behl, Lalit Sharma, Lotfi Aelya, Simona Bunga. Mitochondrial Dysfunction in Huntington's Disease: Pathogenesis and Therapeutic Opportunities. Current drug targets. vol 22. issue 14. 2021-11-29. PMID:33655829. |
huntington's disease (hd) is a prototypical neurodegenerative disease, preferentially disrupting the neurons of the striatum and cortex. |
2021-11-29 |
2023-08-13 |
Not clear |
| Polina S Goncharova, Tatiana K Davydova, Tatiana E Popova, Maxim A Novitsky, Marina M Petrova, Oksana A Gavrilyuk, Mustafa Al-Zamil, Natalia G Zhukova, Regina F Nasyrova, Natalia A Shnayde. Nutrient Effects on Motor Neurons and the Risk of Amyotrophic Lateral Sclerosis. Nutrients. vol 13. issue 11. 2021-11-29. PMID:34836059. |
amyotrophic lateral sclerosis (als) is an incurable chronic progressive neurodegenerative disease with the progressive degeneration of motor neurons in the motor cortex and lower motor neurons in the spinal cord and the brain stem. |
2021-11-29 |
2023-08-13 |
Not clear |
| Caitlin Fowler, Dana Goerzen, Dan Madularu, Gabriel A Devenyi, M Mallar Chakravarty, Jamie Nea. Longitudinal characterization of neuroanatomical changes in the Fischer 344 rat brain during normal aging and between sexes. Neurobiology of aging. vol 109. 2021-11-26. PMID:34775212. |
we identified the greatest vulnerability to aging within the cortex, caudoputamen, hindbrain, and internal capsule, while the influence of sex was strongest in the caudoputamen, hippocampus, nucleus accumbens, and thalamus, many of which are implicated in memory and motor control circuits frequently affected by aging and neurodegenerative disease. |
2021-11-26 |
2023-08-13 |
rat |
| Muna M Hugais, Samantha N Cobos, Seth A Bennett, Jailene Paredes, Genevieve Foran, Mariana P Torrent. Changes in Histone H3 Acetylation on Lysine 9 Accompany Aβ 1-40 Overexpression in an Alzheimer's Disease Yeast Model. microPublication biology. vol 2021. 2021-11-10. PMID:34746682. |
alzheimer's disease (ad), the most common type of dementia, is a neurodegenerative disease characterized by plaques of amyloid-beta (aβ) peptides found in the cerebral cortex of the brain. |
2021-11-10 |
2023-08-13 |
Not clear |
| Jiangxia Ni, Yongfei Ren, Tonghui Su, Jia Zhou, Chaoying Fu, Yi Lu, De'an Li, Jing Zhao, Yunxia Li, Yaoyang Zhang, Yanshan Fang, Nan Liu, Yang Geng, Yelin Che. Loss of TDP-43 function underlies hippocampal and cortical synaptic deficits in TDP-43 proteinopathies. Molecular psychiatry. 2021-10-26. PMID:34697451. |
tdp-43 proteinopathy is linked to neurodegenerative diseases that feature synaptic loss in the cortex and hippocampus, although it remains unclear how tdp-43 regulates mature synapses. |
2021-10-26 |
2023-08-13 |
mouse |
| Katerina Placek, Michael Benatar, Joanne Wuu, Evadnie Rampersaud, Laura Hennessy, Vivianna M Van Deerlin, Murray Grossman, David J Irwin, Lauren Elman, Leo McCluskey, Colin Quinn, Volkan Granit, Jeffrey M Statland, Ted M Burns, John Ravits, Andrea Swenson, Jon Katz, Erik P Pioro, Carlayne Jackson, James Caress, Yuen So, Samuel Maiser, David Walk, Edward B Lee, John Q Trojanowski, Philip Cook, James Gee, Jin Sha, Adam C Naj, Rosa Rademakers, Wenan Chen, Gang Wu, J Paul Taylor, Corey T McMilla. Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis. EMBO molecular medicine. vol 13. issue 1. 2021-10-22. PMID:33270986. |
we demonstrate that a polygenic risk score derived using scca relates to longitudinal cognitive decline in the same cohort and also to in vivo cortical thinning in the orbital frontal cortex, anterior cingulate cortex, lateral temporal cortex, premotor cortex, and hippocampus (n = 90) as well as post-mortem motor cortical neuronal loss (n = 87) in independent als cohorts from the university of pennsylvania integrated neurodegenerative disease biobank. |
2021-10-22 |
2023-08-13 |
Not clear |
| Jessica D Panes, Aline Wendt, Oscar Ramirez-Molina, Patricio A Castro, Jorge Fuentealb. Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure. Neural regeneration research. vol 17. issue 2. 2021-10-22. PMID:34269182. |
in fact, pgc-1α downregulation in different brain areas (hippocampus, substantia nigra, cortex, striatum and spinal cord) that occurs in function of neurological damage including oxidative stress, neuronal loss, and motor disorders has been seen in several animal and cellular models of neurodegenerative diseases. |
2021-10-22 |
2023-08-13 |
mouse |
| Julia Schumacher, Nicola J Ray, Calum A Hamilton, Paul C Donaghy, Michael Firbank, Gemma Roberts, Louise Allan, Rory Durcan, Nicola Barnett, John T O'Brien, John-Paul Taylor, Alan J Thoma. Cholinergic white matter pathways in dementia with Lewy bodies and Alzheimer's disease. Brain : a journal of neurology. 2021-10-04. PMID:34605858. |
however, how white matter projections between the nucleus basalis of meynert and the cortex are altered in neurodegenerative disease is unknown. |
2021-10-04 |
2023-08-13 |
Not clear |
| Peter McColgan, Saskia Helbling, Lenka Vaculčiaková, Kerrin Pine, Konrad Wagstyl, Fakhereh Movahedian Attar, Luke Edwards, Marina Papoutsi, Yongbin Wei, Martijn Pieter Van den Heuvel, Sarah J Tabrizi, Geraint Rees, Nikolaus Weiskop. Relating quantitative 7T MRI across cortical depths to cytoarchitectonics, gene expression and connectomics. Human brain mapping. vol 42. issue 15. 2021-09-25. PMID:34272784. |
ultra-high field mri across the depth of the cortex has the potential to provide anatomically precise biomarkers and mechanistic insights into neurodegenerative disease like huntington's disease that show layer-selective vulnerability. |
2021-09-25 |
2023-08-13 |
human |
| A V Alessenko, U A Gutner, V O Nebogatikov, M A Shupik, A A Ustyugo. [The role of sphingolipids in pathogenesis of amyotrophic lateral sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 121. issue 8. 2021-09-07. PMID:34481449. |
amyotrophic lateral sclerosis (als) is an incurable neurodegenerative disease characterized by selective degeneration of motor neurons of the spinal cord and motor cortex and brain stem. |
2021-09-07 |
2023-08-13 |
Not clear |
| Jian-Hong Qi, Fang-Xu Dong, Xiao-Long Wan. Exploring targets and signaling pathways of paeonol involved in relieving inflammation based on modern technology. Molecular diversity. 2021-09-03. PMID:34463943. |
paeonol, derived from natural plants (moutan cortex), has a wide range of biological effects, including anti-inflammatory and antitumor effects as well as favorable effects against cardiovascular and neurodegenerative diseases. |
2021-09-03 |
2023-08-13 |
Not clear |
| Md Ataur Rahman, Md Abdul Hannan, Md Jamal Uddin, Md Saidur Rahman, Md Mamunur Rashid, Bonglee Ki. Exposure to Environmental Arsenic and Emerging Risk of Alzheimer's Disease: Perspective Mechanisms, Management Strategy, and Future Directions. Toxics. vol 9. issue 8. 2021-08-31. PMID:34437506. |
alzheimer's disease (ad) is one of the most prevailing neurodegenerative diseases, characterized by memory dysfunction and the presence of hyperphosphorylated tau and amyloid β (aβ) aggregates in multiple brain regions, including the hippocampus and cortex. |
2021-08-31 |
2023-08-13 |
human |