| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Eijkenboom, A Blokland, F J van der Staa. Modelling cognitive dysfunctions with bilateral injections of ibotenic acid into the rat entorhinal cortex. Neuroscience. vol 101. issue 1. 2001-02-15. PMID:11068134. |
rats lesioned by bilateral injections of ibotenic acid into the entorhinal cortex provide an interesting and reliable model for investigating cognitive dysfunctions in neurodegenerative diseases, stroke or traumatic brain injury. |
2001-02-15 |
2023-08-12 |
rat |
| S S Ingrand, A Wahl, S Favrelière, F Barbot, C Tallinea. Quantification of long-chain aldehydes by gas chromatography coupled to mass spectrometry as a tool for simultaneous measurement of plasmalogens and their aldehydic breakdown products. Analytical biochemistry. vol 280. issue 1. 2000-06-30. PMID:10805522. |
two of these are affected in neurodegenerative diseases (cerebral cortex and hippocampus) and one is rich in white matter (cerebellum). |
2000-06-30 |
2023-08-12 |
rat |
| E Falke, L Y Han, S E Arnol. Absence of neurodegeneration in the thalamus and caudate of elderly patients with schizophrenia. Psychiatry research. vol 93. issue 2. 2000-05-09. PMID:10725527. |
diagnostic neuropathologic studies have excluded known neurodegenerative diseases as the cause of this dementia, and in a previous quantitative investigation of neurodegeneration and neural injury in this population we found no abnormalities in the cerebral cortex. |
2000-05-09 |
2023-08-12 |
human |
| P Giannakopoulos, E Kövari, L Buée, J Shioi, P R Hof, N K Robakis, C Boura. Presenilin-1 expression in Pick's disease. Acta neuropathologica. vol 98. issue 5. 1999-12-10. PMID:10541872. |
to examine whether this phenomenon also occurs in other neurodegenerative diseases, we performed a quantitative immunocytochemical study of ps-1 distribution in the cerebral cortex of pick's disease (pid) cases and non-demented individuals. |
1999-12-10 |
2023-08-12 |
Not clear |
| P M Thompson, J Moussai, S Zohoori, A Goldkorn, A A Khan, M S Mega, G W Small, J L Cummings, A W Tog. Cortical variability and asymmetry in normal aging and Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). vol 8. issue 6. 1999-06-02. PMID:9758213. |
extreme variations in the sulcal patterns of the human cortex have made it difficult to identify diffuse and focal variations in cortical structure in neurodegenerative disease. |
1999-06-02 |
2023-08-12 |
human |
| R Dawson, E G Marschall, K C Chan, W J Millard, B Eppler, T A Patterso. Neurochemical and neurobehavioral effects of neonatal administration of beta-N-methylamino-L-alanine and 3,3'-iminodipropionitrile. Neurotoxicology and teratology. vol 20. issue 2. 1998-05-14. PMID:9536463. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease that is characterized by a loss of motor neurons in the spinal cord, brain stem, and cortex. |
1998-05-14 |
2023-08-12 |
rat |
| S E Arnold, J Q Trojanowsk. Recent advances in defining the neuropathology of schizophrenia. Acta neuropathologica. vol 92. issue 3. 1997-02-03. PMID:8870823. |
while substantial controversy exists in all areas, in sum: (1) diagnostic neuropathological investigations find only assorted and nonspecific abnormalities in the brains of schizophrenics that are likely to be representative of lesions found in age-compatible control groups; (2) morphometric studies of gross structures generally confirm the clinical in vivo neuroimaging findings of enlarged ventricles, decreased size of ventromedial temporal lobe structures, and decreased parahippocampal cortical thickness; (3) morphometric microscopy studies find frequent alterations in neuron density and decreased neuron size in limbic, temporal, and frontal regions; (4) investigations of connectivity are at an early stage but describe abnormal dendritic spine densities in the cortex, various changes in synaptic vesicle protein expression in limbic, temporal, and frontal cortices, and alterations in glutamatergic, catecholaminergic, and intrinsic innervation in anterior cingulate cortex- together, these findings suggest a "miswiring" in the schizophrenic brain; (5) investigations of aberrant neurodevelopment in schizophrenia describe abnormalities in cortical cytoarchitecture and several developmentally regulated proteins in the hippocampal region suggesting abnormal neuronal migration, differentiation, and/or cell pruning; and (6) studies of neurodegeneration and neural injury find a general lack of neurodegenerative disease lesions or ongoing astrocytosis that would indicate post-maturational neural injury. |
1997-02-03 |
2023-08-12 |
Not clear |
| L F Agnati, P Cortelli, R Pettersson, K Fux. The concept of trophic units in the central nervous system. Progress in neurobiology. vol 46. issue 6. 1996-02-13. PMID:8545544. |
the concept of trophic unit may help to understand some features of neurodegenerative diseases, for example, the clustering of tangles in the neocortex and in the entorhinal cortex of alzheimer's patients [corrected]. |
1996-02-13 |
2023-08-12 |
Not clear |
| K Nihei, A C McKee, N W Kowal. Patterns of neuronal degeneration in the motor cortex of amyotrophic lateral sclerosis patients. Acta neuropathologica. vol 86. issue 1. 1993-10-08. PMID:8396837. |
these histochemical results suggest that cortical degeneration in als is distinctive from other neurodegenerative diseases affecting cerebral cortex. |
1993-10-08 |
2023-08-12 |
Not clear |
| J P Hornung, N De Tribolet, I Tör. Morphology and distribution of neuropeptide-containing neurons in human cerebral cortex. Neuroscience. vol 51. issue 2. 1993-01-19. PMID:1281528. |
the present study underlines several aspects of the organization of the neuropeptide-containing neurons of the human cerebral cortex, which are of particular interest in the light of the involvement of these neurons in several neurodegenerative diseases. |
1993-01-19 |
2023-08-11 |
human |
| Y Ohyagi, K Takahashi, Y Satoh, T Makifuchi, T Tabir. Cerebral cortical amyloid protein precursor mRNA expression is similar in Alzheimer's disease and other neurodegenerative diseases. Journal of the neurological sciences. vol 111. issue 1. 1992-11-12. PMID:1402996. |
the expression of 3 beta-amyloid protein precursor (app) mrnas (695, 751, and 770) in the cerebral cortex in alzheimer's disease and other neurodegenerative diseases was analyzed by the s1 nuclease protection assay. |
1992-11-12 |
2023-08-11 |
Not clear |
| L F Levisohn, O Isacso. Excitotoxic lesions of the rat entorhinal cortex. Effects of selective neuronal damage on acquisition and retention of a non-spatial reference memory task. Brain research. vol 564. issue 2. 1992-06-04. PMID:1810624. |
this functional anatomical study of the entorhinal cortex demonstrates the importance of the entorhinal cortex in memory retention, and raises the possibility that functional deficits in certain neurodegenerative diseases may be modeled by partial neuronal loss in the entorhinal cortex. |
1992-06-04 |
2023-08-11 |
rat |
| R Van der Neut, W H Gispen, P R Bä. Serum from patients with amyotrophic lateral sclerosis induces the expression of B-50/GAP-43 and neurofilament in cultured rat fetal spinal neurons. Molecular and chemical neuropathology. vol 14. issue 3. 1992-01-03. PMID:1835579. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease affecting motor neurons in the spinal cord, brain stem, and cortex. |
1992-01-03 |
2023-08-11 |
rat |
| A A Carboni, W G Lavelle, C L Barnes, P B Cipollon. Neurons of the lateral entorhinal cortex of the rhesus monkey: a Golgi, histochemical, and immunocytochemical characterization. The Journal of comparative neurology. vol 291. issue 4. 1990-05-30. PMID:1691746. |
this study identifies the neuronal types of the rhesus monkey lateral entorhinal cortex (lec) and discusses the importance of these data in the context of the connectional patterns of the lec and the possible role of these cells in neurodegenerative diseases. |
1990-05-30 |
2023-08-11 |
monkey |
| P H Stephens, P Tagari, A C Cuell. Ethylcholine mustard aziridinium ion lesions of the rat cortex result in retrograde degeneration of basal forebrain cholinergic neurons: implications for animal models of neurodegenerative disease. Neurochemical research. vol 12. issue 7. 1987-09-11. PMID:3614511. |
ethylcholine mustard aziridinium ion lesions of the rat cortex result in retrograde degeneration of basal forebrain cholinergic neurons: implications for animal models of neurodegenerative disease. |
1987-09-11 |
2023-08-11 |
rat |
| S Yoshida, Y Yase, S Iwata, K Sasagawa, K M Che. [Relationship between metal metabolism and senile changes in the hippocampal cortex of neurodegenerative disease cases in Japan and Guam]. Rinsho shinkeigaku = Clinical neurology. vol 27. issue 1. 1987-05-29. PMID:3568504. |
[relationship between metal metabolism and senile changes in the hippocampal cortex of neurodegenerative disease cases in japan and guam]. |
1987-05-29 |
2023-08-11 |
Not clear |