| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sachin Patil, Deebika Balu, Joseph Melrose, Christina Cha. Brain region-specificity of palmitic acid-induced abnormalities associated with Alzheimer's disease. BMC research notes. vol 1. 2011-07-14. PMID:18710535. |
alzheimer's disease (ad) is a progressive, neurodegenerative disease mostly affecting the basal forebrain, cortex and hippocampus whereas the cerebellum is relatively spared. |
2011-07-14 |
2023-08-12 |
Not clear |
| P Calissano, C Matrone, G Amador. Apoptosis and in vitro Alzheimer disease neuronal models. Communicative & integrative biology. vol 2. issue 2. 2011-07-14. PMID:19513272. |
alzheimer disease (ad) is a human neurodegenerative disease characterized by co-existence of extracellular senile plaques (sp) and neurofibrillary tangles (nft) associated with an extensive neuronal loss, primarily in the cerebral cortex and hippocampus. |
2011-07-14 |
2023-08-12 |
human |
| James C Dodge, Christopher M Treleaven, Jonathan A Fidler, Mark Hester, Amanda Haidet, Chalonda Handy, Meghan Rao, Amy Eagle, Jennifer C Matthews, Tatyana V Taksir, Seng H Cheng, Lamya S Shihabuddin, Brian K Kaspa. AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice. Molecular therapy : the journal of the American Society of Gene Therapy. vol 18. issue 12. 2011-04-18. PMID:20859261. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by motor neuron cell death in the cortex, brainstem, and spinal cord. |
2011-04-18 |
2023-08-12 |
mouse |
| Martina Minnerop, Eileen Lüders, Karsten Specht, Jürgen Ruhlmann, Nicole Schimke, Paul M Thompson, Yi Y Chou, Arthur W Toga, Michael Abele, Ullrich Wüllner, Thomas Klockgethe. Callosal tissue loss in multiple system atrophy--a one-year follow-up study. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 15. 2011-02-25. PMID:20623690. |
multiple system atrophy (msa) is a neurodegenerative disease not only affecting the basal ganglia, brainstem, cerebellum, and intermediolateral cell columns of the spinal cord but also the cerebral cortex. |
2011-02-25 |
2023-08-12 |
Not clear |
| Reihaneh Hoveida, Hojjatallah Alaei, Shahrbanoo Oryan, Kazem Parivar, Parham Reis. Treadmill running improves spatial memory in an animal model of Alzheimer's disease. Behavioural brain research. vol 216. issue 1. 2011-02-18. PMID:20709113. |
alzheimer's disease (ad) is a progressive neurodegenerative disease that is characterized by a decline in cognitive function and severe neuronal loss in the cerebral cortex and certain subcortical regions of the brain including nucleus basalis magnocellularis (nbm) that play an important role in learning and memory. |
2011-02-18 |
2023-08-12 |
rat |
| Tatiana R Rosenstock, Ana I Duarte, A Cristina Reg. Mitochondrial-associated metabolic changes and neurodegeneration in Huntington's disease - from clinical features to the bench. Current drug targets. vol 11. issue 10. 2011-01-05. PMID:20840066. |
huntington's disease (hd) is a genetic neurodegenerative disease selectively leading to striatal neurodegeneration, but also affecting the cortex and the hypothalamus. |
2011-01-05 |
2023-08-12 |
Not clear |
| Jose A Rodríguez-Navarro, Laura Rodríguez, María J Casarejos, Rosa M Solano, Ana Gómez, Juan Perucho, Ana María Cuervo, Justo García de Yébenes, María A Men. Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation. Neurobiology of disease. vol 39. issue 3. 2010-11-16. PMID:20546895. |
tauopathies are neurodegenerative diseases, sporadic or familial, mainly characterized by dementia and parkinsonism associated to atrophy of the frontotemporal cortex and the basal ganglia, with deposition of abnormal tau in brain. |
2010-11-16 |
2023-08-12 |
mouse |
| Mritunjay Pandey, Kochupurackal P Mohanakumar, Rajamma Ush. Mitochondrial functional alterations in relation to pathophysiology of Huntington's disease. Journal of bioenergetics and biomembranes. vol 42. issue 3. 2010-10-08. PMID:20464463. |
huntington's disease (hd) is an autosomal dominant neurodegenerative disease which is characterized by psychiatric symptoms, involuntary choreiform movements and dementia with maximum degeneration occurring in striatum and cerebral cortex. |
2010-10-08 |
2023-08-12 |
human |
| Chiung-Chun Huang, Cheng-Che Lee, Kuei-Sen Hs. The role of insulin receptor signaling in synaptic plasticity and cognitive function. Chang Gung medical journal. vol 33. issue 2. 2010-08-06. PMID:20438663. |
several lines of work in both laboratory animals and humans suggest that when neurons in cognitive brain regions such as the hippocampus and cerebral cortex do not make enough insulin or cannot respond to insulin properly, everything from very mild memory loss to severe neurodegenerative diseases can result. |
2010-08-06 |
2023-08-12 |
Not clear |
| Ricardo Gredilla, Christian Garm, Rikke Holm, Vilhelm A Bohr, Tinna Stevnsne. Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions. Neurobiology of aging. vol 31. issue 6. 2010-07-13. PMID:18701195. |
in the current study we investigated the efficiency of the ber pathway throughout the murine lifespan in mitochondria from cortex and hippocampus, regions that are central in mammalian cognition, and which are severely affected during aging and in neurodegenerative diseases. |
2010-07-13 |
2023-08-12 |
mouse |
| Doris C V Thu, Dorothy E Oorschot, Lynette J Tippett, Alissa L Nana, Virginia M Hogg, Beth J Synek, Ruth Luthi-Carter, Henry J Waldvogel, Richard L M Faul. Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease. Brain : a journal of neurology. vol 133. issue Pt 4. 2010-04-27. PMID:20375136. |
huntington's disease is an autosomal dominant inherited neurodegenerative disease with motor symptoms that are variably co-expressed with mood and cognitive symptoms, and in which variable neuronal degeneration is also observed in the basal ganglia and the cerebral cortex. |
2010-04-27 |
2023-08-12 |
Not clear |
| I Mateo, J Infante, P Sánchez-Juan, I García-Gorostiaga, E Rodríguez-Rodríguez, J L Vázquez-Higuera, J Berciano, O Combarro. Serum heme oxygenase-1 levels are increased in Parkinson's disease but not in Alzheimer's disease. Acta neurologica Scandinavica. vol 121. issue 2. 2010-03-04. PMID:19785642. |
oxidative stress is implicated in parkinson's disease (pd) and alzheimer's disease (ad), and heme oxygenase-1 (ho-1) is a potent antioxidant overexpressed in pd substantia nigra and ad cerebral cortex and hippocampus, indicating a possible up-regulation of antioxidant defenses in both neurodegenerative diseases. |
2010-03-04 |
2023-08-12 |
Not clear |
| M J Dowie, H B Bradshaw, M L Howard, L F B Nicholson, R L M Faull, A J Hannan, M Glas. Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19524019. |
huntington's disease (hd) is an inherited neurodegenerative disease characterised by cell dysfunction and death in the basal ganglia and cortex. |
2009-12-15 |
2023-08-12 |
mouse |
| Rubén Fernández-Santiago, Sabine Hoenig, Peter Lichtner, Anne-Dorte Sperfeld, Manu Sharma, Daniela Berg, Oliver Weichenrieder, Thomas Illig, Katharina Eger, Thomas Meyer, Johanna Anneser, Christoph Münch, Stephan Zierz, Thomas Gasser, Albert Ludolp. Identification of novel Angiogenin (ANG) gene missense variants in German patients with amyotrophic lateral sclerosis. Journal of neurology. vol 256. issue 8. 2009-11-13. PMID:19363631. |
amyotrophic lateral sclerosis (als) is a fatal progressive neurodegenerative disease characterized by the selective death of motor neurons in the motor cortex, brain stem and spinal cord. |
2009-11-13 |
2023-08-12 |
Not clear |
| Daniel Offen, Yael Barhum, Eldad Melamed, Norbert Embacher, Christoph Schindler, Gerhard Ransmay. Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant. Journal of molecular neuroscience : MN. vol 38. issue 2. 2009-08-31. PMID:18651250. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by loss of motor neurons in the cerebral cortex, brain stem, and spinal cord. |
2009-08-31 |
2023-08-12 |
mouse |
| b' L Tolosa, M Mir, G Olmos, J Llad\\xc3\\xb. Vascular endothelial growth factor protects motoneurons from serum deprivation-induced cell death through phosphatidylinositol 3-kinase-mediated p38 mitogen-activated protein kinase inhibition. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19041930.' |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective degeneration and death of motoneurons in the spinal cord, brainstem and motor cortex which causes progressive muscle weakness and paralysis. |
2009-05-20 |
2023-08-12 |
rat |
| V Mylius, A Gerstner, M Peters, H Prokisch, A Leonhardt, D Hellwig, F Roseno. Low-frequency rTMS of the premotor cortex reduces complex movement patterns in a patient with pantothenate kinase-associated neurodegenerative disease (PKAN). Neurophysiologie clinique = Clinical neurophysiology. vol 39. issue 1. 2009-05-08. PMID:19268844. |
low-frequency rtms of the premotor cortex reduces complex movement patterns in a patient with pantothenate kinase-associated neurodegenerative disease (pkan). |
2009-05-08 |
2023-08-12 |
Not clear |
| V Mylius, A Gerstner, M Peters, H Prokisch, A Leonhardt, D Hellwig, F Roseno. Low-frequency rTMS of the premotor cortex reduces complex movement patterns in a patient with pantothenate kinase-associated neurodegenerative disease (PKAN). Neurophysiologie clinique = Clinical neurophysiology. vol 39. issue 1. 2009-05-08. PMID:19268844. |
pantothenate kinase-associated neurodegenerative disease (pkan) is a secondary generalized dystonia associated with an accumulation of iron in the basal ganglia and increased motor cortex excitability. |
2009-05-08 |
2023-08-12 |
Not clear |
| S V Sarantseva, O I Bol'shakova, S I Timoshenko, D I Rodin, M P Vitek, A L Shvartsma. [Studying pathogenesis of Alzheimer's disease in a Drosophila melanogaster model: human APP overexpression in the brain of transgenic flies leads to deficit of the synaptic protein synaptotagmin]. Genetika. vol 45. issue 1. 2009-03-27. PMID:19239106. |
alzheimer's disease (ad) is a progressive neurodegenerative disease whose main pathomorphological sign is synapse degeneration in the cortex and hippocampus. |
2009-03-27 |
2023-08-12 |
human |
| Irene Carunchio, Cristiana Mollinari, Massimo Pieri, Daniela Merlo, Cristina Zon. GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis. The European journal of neuroscience. vol 28. issue 7. 2009-01-30. PMID:18973555. |
amyotrophic lateral sclerosis is a neurodegenerative disease characterized by the selective degeneration of motor neurons in the spinal cord, brainstem and cerebral cortex. |
2009-01-30 |
2023-08-12 |
Not clear |