| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Yu, Yingjun Guan, Xin Wu, Yanchun Chen, Zhijun Liu, Hongmei Du, Xin Wan. Wnt Signaling is altered by spinal cord neuronal dysfunction in amyotrophic lateral sclerosis transgenic mice. Neurochemical research. vol 38. issue 9. 2014-03-10. PMID:23784673. |
amyotrophic lateral sclerosis (als) is a chronic neurodegenerative disease characterized by progressive degeneration of the motor neurons in the cortex, brainstem, and spinal cord. |
2014-03-10 |
2023-08-12 |
mouse |
| Ipek Baysal, Samiye Yabanoglu-Ciftci, Yeliz Tunc-Sarisozen, Kezban Ulubayram, Gulberk Uca. Interaction of selegiline-loaded PLGA-b-PEG nanoparticles with beta-amyloid fibrils. Journal of neural transmission (Vienna, Austria : 1996). vol 120. issue 6. 2014-01-10. PMID:23420173. |
alzheimer's disease (ad) is an irreversible and progressive neurodegenerative disease that is caused by the irreversible loss of neurons in the hippocampus and cortex regions of the brain. |
2014-01-10 |
2023-08-12 |
Not clear |
| S Bavithra, K Selvakumar, G Krishnamoorthy, P Venkataraman, J Arunakara. Melatonin attenuates polychlorinated biphenyls induced apoptosis in the neuronal cells of cerebral cortex and cerebellum of adult male rats--in vivo. Environmental toxicology and pharmacology. vol 36. issue 1. 2013-12-12. PMID:23619521. |
the progressive loss of neurons in cerebral cortex and cerebellum, leads to various neurodegenerative diseases. |
2013-12-12 |
2023-08-12 |
rat |
| Hui Sun, Sarah Knippenberg, Nadine Thau, Daniela Ragancokova, Sonja Körner, Dongya Huang, Reinhard Dengler, Klaus Döhler, Susanne Petr. Therapeutic potential of N-acetyl-glucagon-like peptide-1 in primary motor neuron cultures derived from non-transgenic and SOD1-G93A ALS mice. Cellular and molecular neurobiology. vol 33. issue 3. 2013-09-04. PMID:23271639. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the death of motor neurons (mn) in the motor cortex, brain stem, and spinal cord. |
2013-09-04 |
2023-08-12 |
mouse |
| Guan-Ting Liu, Chi-Shin Hwang, Chia-Hung Hsieh, Chih-Hao Lu, Sunny Li-Yun Chang, Jin-Ching Lee, Chien-Fu Huang, Hao-Teng Chan. Eosinophil-derived neurotoxin is elevated in patients with amyotrophic lateral sclerosis. Mediators of inflammation. vol 2013. 2013-08-19. PMID:23533305. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by loss of motor neurons in the brainstem, motor cortex, and spinal cord. |
2013-08-19 |
2023-08-12 |
Not clear |
| L R Herron, G B Mile. Gender-specific perturbations in modulatory inputs to motoneurons in a mouse model of amyotrophic lateral sclerosis. Neuroscience. vol 226. 2013-04-22. PMID:23000617. |
the fatal neurodegenerative disease amyotrophic lateral sclerosis (als) is characterised by loss of motoneurons of the brainstem and spinal cord, and corticospinal neurons of the motor cortex. |
2013-04-22 |
2023-08-12 |
mouse |
| Alida Spalloni, Michele Nutini, Patrizia Longon. Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis. Biochimica et biophysica acta. vol 1832. issue 2. 2013-03-14. PMID:23200922. |
amyotrophic lateral sclerosis (als) is an adult onset neurodegenerative disease pathologically characterized by the massive loss of motor neurons in the spinal cord, brain stem and cerebral cortex. |
2013-03-14 |
2023-08-12 |
Not clear |
| Luuk van der Velden, Johannes A van Hooft, Pascal Chamea. Altered dendritic complexity affects firing properties of cortical layer 2/3 pyramidal neurons in mice lacking the 5-HT3A receptor. Journal of neurophysiology. vol 108. issue 5. 2013-02-01. PMID:22696545. |
alterations of dendritic complexity, as observed in several pathological conditions such as neurodegenerative diseases or neurodevelopmental disorders, may thus not only affect the input to layer 2/3 pyramidal neurons but also shape their firing pattern and consequently alter the information processing in the cortex. |
2013-02-01 |
2023-08-12 |
mouse |
| Antonio José da Rocha, Antonio Carlos Martins Maia Júnio. Is magnetic resonance imaging a plausible biomarker for upper motor neuron degeneration in amyotrophic lateral sclerosis/primary lateral sclerosis or merely a useful paraclinical tool to exclude mimic syndromes? A critical review of imaging applicability in clinical routine. Arquivos de neuro-psiquiatria. vol 70. issue 7. 2013-02-01. PMID:22836461. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease that affects motor neurons in the cerebral cortex, brainstem, and spinal cord, brain regions in which conventional magnetic resonance imaging is often uninformative. |
2013-02-01 |
2023-08-12 |
Not clear |
| Abdul Qayyum Rana, Hamza Ansari, Ishraq Siddiqu. The relationship between arm dystonia in corticobasal degeneration and handedness. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 19. issue 8. 2012-11-20. PMID:22705141. |
corticobasal degeneration is a progressive neurodegenerative disease involving the cerebral cortex and basal ganglia and leads primarily to motor symptoms and cognitive dysfunction. |
2012-11-20 |
2023-08-12 |
Not clear |
| Hak Ju Lee, Da Hyun Lyu, Uk Koo, Kung-Woo Nam, Seong Su Hong, Kem Ok Kim, Kyeong Ho Kim, Dongho Lee, Woongchon Ma. Protection of prenylated flavonoids from Mori Cortex Radicis (Moraceae) against nitric oxide-induced cell death in neuroblastoma SH-SY5Y cells. Archives of pharmacal research. vol 35. issue 1. 2012-09-28. PMID:22297755. |
even though further evaluations are necessary in vitro and in vivo study, we carefully suggest that some prenylated flavonoids from mori cortex radicis might protect neuronal cells from neurodegenerative diseases. |
2012-09-28 |
2023-08-12 |
Not clear |
| b' Mauro Cozzolino, Maria Teresa Carr\\xc3\\xa. Mitochondrial dysfunction in ALS. Progress in neurobiology. vol 97. issue 2. 2012-09-14. PMID:21827820.' |
in the present article, we review the many facets of mitochondrial dysfunction in amyotrophic lateral sclerosis (als), a fatal neurodegenerative disease due to loss of upper motor neurons in cerebral cortex and lower motor neurons in brainstem and spinal cord. |
2012-09-14 |
2023-08-12 |
Not clear |
| Valeria Uribe, Bibiana K Y Wong, Rona K Graham, Corey L Cusack, Niels H Skotte, Mahmoud A Pouladi, Yuanyun Xie, Konstantin Feinberg, Yimiao Ou, Yingbin Ouyang, Yu Deng, Sonia Franciosi, Nagat Bissada, Amanda Spreeuw, Weining Zhang, Dagmar E Ehrnhoefer, Kuljeet Vaid, Freda D Miller, Mohanish Deshmukh, David Howland, Michael R Hayde. Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice. Human molecular genetics. vol 21. issue 9. 2012-09-06. PMID:22262731. |
the age-dependent behavioral and region-specific neuroanatomical changes observed in the casp6-/- mice suggest that casp6 deficiency has a more pronounced effect in brain regions that are involved in neurodegenerative diseases, such as the striatum in hd and the cortex in ad. |
2012-09-06 |
2023-08-12 |
mouse |
| Renata P Lerner, Luz Del Carmen G Trejo Martinez, Chunni Zhu, Marie-Françoise Chesselet, Miriam A Hicke. Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease. Brain research bulletin. vol 87. issue 6. 2012-07-23. PMID:22326483. |
huntington's disease (hd) is a progressive neurodegenerative disease characterized by progressive atrophy of the striatum, cerebral cortex, and white matter tracks. |
2012-07-23 |
2023-08-12 |
mouse |
| Dinkar Kulshreshtha, K Vijayalakshmi, Phalguni Anand Alladi, T N Sathyaprabha, Atchayaram Nalini, T R Raj. Vascular endothelial growth factor attenuates neurodegenerative changes in the NSC-34 motor neuron cell line induced by cerebrospinal fluid of sporadic amyotrophic lateral sclerosis patients. Neuro-degenerative diseases. vol 8. issue 5. 2012-05-08. PMID:21389676. |
motor neuron disease or amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective death of motor neurons in the spinal cord as well as motor cortex. |
2012-05-08 |
2023-08-12 |
Not clear |
| Michael Gold, Stefan Lorenzl, Alistair J Stewart, Bruce H Morimoto, David R Williams, Illana Goze. Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy. Neuropsychiatric disease and treatment. vol 8. 2012-03-20. PMID:22347799. |
progressive supranuclear palsy (psp) is a rare neurodegenerative disease characterized by the accumulation of tau protein aggregates in the basal ganglia, brainstem and cerebral cortex leading to rapid disease progression and death. |
2012-03-20 |
2023-08-12 |
Not clear |
| Natacha Coppieters, Mike Draguno. Epigenetics in Alzheimer's disease: a focus on DNA modifications. Current pharmaceutical design. vol 17. issue 31. 2012-03-19. PMID:21902668. |
ad is a complex neurodegenerative disease characterized by a progressive decline in cognitive functions, neuronal cell loss and by the presence of β amyloid (aβ) plaques and neurofibrillary tangles (nfts) in the cortex. |
2012-03-19 |
2023-08-12 |
human |
| Michele Nutini, Valerio Frazzini, Claudia Marini, Alida Spalloni, Stefano L Sensi, Patrizia Longon. Zinc pre-treatment enhances NMDAR-mediated excitotoxicity in cultured cortical neurons from SOD1(G93A) mouse, a model of amyotrophic lateral sclerosis. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21056589. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease affecting motor neurons in the spinal cord and cortex. |
2012-01-18 |
2023-08-12 |
mouse |
| J A Bermúdez-Lugo, M C Rosales-Hernández, O Deeb, J Trujillo-Ferrara, J Correa-Basurt. In silico methods to assist drug developers in acetylcholinesterase inhibitor design. Current medicinal chemistry. vol 18. issue 8. 2011-08-01. PMID:21291371. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by a low acetylcholine (ach) concentration in the hippocampus and cortex. |
2011-08-01 |
2023-08-12 |
Not clear |
| Ewa Naganska, Ewa Matyj. Amyotrophic lateral sclerosis - looking for pathogenesis and effective therapy. Folia neuropathologica. vol 49. issue 1. 2011-07-20. PMID:21455838. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which dramatically reduces life expectancy. |
2011-07-20 |
2023-08-12 |
Not clear |