| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth Maria Doerr, Barbara Carretti, Enrico Toffalini, Silvia Lanfranchi, Chiara Meneghett. Developmental Trajectories in Spatial Visualization and Mental Rotation in Individuals with Down Syndrome. Brain sciences. vol 11. issue 5. 2021-06-15. PMID:34068802. |
the analysis of developmental trajectories of visuospatial abilities in individuals with down syndrome (ds) remains an unexplored field of investigation to examine in depth. |
2021-06-15 |
2023-08-13 |
Not clear |
| Martina Fontana, Maria Carmen Usai, Sandra Pellizzoni, Maria Chiara Passolungh. Inhibitory Dimensions and Delay of Gratification: A Comparative Study on Individuals with Down Syndrome and Typically Developing Children. Brain sciences. vol 11. issue 5. 2021-06-15. PMID:34069218. |
while previous research on inhibition in people with down syndrome (ds) reported contradictory results, with no explicit theoretical model, on the other hand, a more homogeneous impaired profile on the delay of gratification skills emerged. |
2021-06-15 |
2023-08-13 |
Not clear |
| Chiara Locatelli, Sara Onnivello, Francesca Antonaros, Agnese Feliciello, Sonia Filoni, Sara Rossi, Francesca Pulina, Chiara Marcolin, Renzo Vianello, Enrico Toffalini, Giuseppe Ramacieri, Anna Martelli, Giulia Procaccini, Giacomo Sperti, Maria Caracausi, Maria Chiara Pelleri, Lorenza Vitale, Gian Luca Pirazzoli, Pierluigi Strippoli, Guido Cocchi, Allison Piovesan, Silvia Lanfranch. Is the Age of Developmental Milestones a Predictor for Future Development in Down Syndrome? Brain sciences. vol 11. issue 5. 2021-06-15. PMID:34069813. |
down syndrome (ds) is the most common genetic alteration responsible for intellectual disability, which refers to deficits in both intellectual and adaptive functioning. |
2021-06-15 |
2023-08-13 |
Not clear |
| Chiara Locatelli, Sara Onnivello, Francesca Antonaros, Agnese Feliciello, Sonia Filoni, Sara Rossi, Francesca Pulina, Chiara Marcolin, Renzo Vianello, Enrico Toffalini, Giuseppe Ramacieri, Anna Martelli, Giulia Procaccini, Giacomo Sperti, Maria Caracausi, Maria Chiara Pelleri, Lorenza Vitale, Gian Luca Pirazzoli, Pierluigi Strippoli, Guido Cocchi, Allison Piovesan, Silvia Lanfranch. Is the Age of Developmental Milestones a Predictor for Future Development in Down Syndrome? Brain sciences. vol 11. issue 5. 2021-06-15. PMID:34069813. |
according to this, individuals with down syndrome (ds) reach developmental milestones (e.g., sitting, walking, and babbling) in the same order as their typically developing peers, but later in life. |
2021-06-15 |
2023-08-13 |
Not clear |
| b' Ay\\xc5\\x9fe T\\xc3\\xbclin Mansur, Sevgi K\\xc3\\xbcll\\xc3\\xb. A solitary lesion of idiopathic calcinosis cutis in an infant: subepidermal nodular calcinosis or milia-like idiopathic calcinosis cutis? Dermatology online journal. vol 27. issue 5. 2021-06-15. PMID:34118820.' |
association with down syndrome (ds) has been reported in up to two-third of the cases with micc, but not in scn. |
2021-06-15 |
2023-08-13 |
Not clear |
| Pamela Banta Lavenex, Pierre Lavene. A Critical Review of Spatial Abilities in Down and Williams Syndromes: Not All Space Is Created Equal. Frontiers in psychiatry. vol 12. 2021-06-15. PMID:34122185. |
down syndrome (ds, trisomy 21) and williams syndrome (ws) are two neurodevelopmental disorders of genetic origin that are accompanied by mild to moderate intellectual disability but exhibit distinct cognitive profiles. |
2021-06-15 |
2023-08-13 |
human |
| David B Keator, Michael J Phelan, Lisa Taylor, Eric Doran, Sharon Krinsky-McHale, Julie Price, Erin E Ballard, William C Kreisl, Christy Hom, Dana Nguyen, Margaret Pulsifer, Florence Lai, Diana H Rosas, Adam M Brickman, Nicole Schupf, Michael A Yassa, Wayne Silverman, Ira T Lot. Down syndrome: Distribution of brain amyloid in mild cognitive impairment. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-06-10. PMID:32435685. |
down syndrome (ds) is associated with a higher risk of dementia. |
2021-06-10 |
2023-08-13 |
Not clear |
| Marcelo Aguiar Costa-Lima, Hazel Nunes Barboza, Joissy Aprigio, Cláudia de Melo Moura, Thereza Fonseca Quirico-Santos, Márcia Gonçalves Ribeiro, Márcia Rodrigues Amori. Dihydrofolate Reductase (DHFR) del19bp Polymorphism and Down Syndrome Offspring. Journal of molecular neuroscience : MN. vol 70. issue 9. 2021-06-10. PMID:32445071. |
down syndrome (ds) is the most common form of mental disability of genetic etiology. |
2021-06-10 |
2023-08-13 |
Not clear |
| Fiorenza Stagni, Andrea Giacomini, Marco Emili, Beatrice Uguagliati, Maria Paola Bonasoni, Renata Bartesaghi, Sandra Guid. Neuroanatomical alterations in higher-order thalamic nuclei of fetuses with Down syndrome. Clinical neurology and neurosurgery. vol 194. 2021-06-10. PMID:32480293. |
down syndrome (ds) is a genetic condition characterized by cognitive disability starting from infancy. |
2021-06-10 |
2023-08-13 |
Not clear |
| Logan Manikam, Monica Lakhanpaul, Anne G M Schilder, Peter Littlejohns, Meghan A Cupp, Emma C Alexander, Andrew Haywar. Effect of antibiotics in preventing hospitalizations from respiratory tract infections in children with Down syndrome. Pediatric pulmonology. vol 56. issue 1. 2021-06-09. PMID:32997386. |
children with down syndrome (ds) are at high risk of respiratory tract infections (rtis) due to anatomical variations, comorbidities, and immune system immaturity. |
2021-06-09 |
2023-08-13 |
Not clear |
| Matteo Zago, Claudia Condoluci, Carlotta Maria Manzia, Marta Pili, Marta Elisa Manunza, Manuela Gall. Multi-segmental postural control patterns in down syndrome. Clinical biomechanics (Bristol, Avon). vol 82. 2021-06-09. PMID:33477082. |
patients with down syndrome (ds) exhibit less efficient and unstable standing postural control. |
2021-06-09 |
2023-08-13 |
Not clear |
| Mireya Orozco-Vela, Alfredo Corona-Rivera, Rosa Margarita Cruz-Osorio, Lucero Mendoza-Maldonado, Aurea Márquez-Mora, César Cenobio Barba-Barba, Christian Peña-Padilla, Alejandra Baldomero-López, Lucina Bobadilla-Morales, Jorge Román Corona-River. Complete blood count differences in a cohort of Down syndrome neonates with transient abnormal myelopoiesis screened for GATA1 pathogenic variants. American journal of medical genetics. Part A. vol 182. issue 9. 2021-06-08. PMID:32681702. |
transient abnormal myelopoiesis (tam) raises the risk for acute myeloid leukemia of down syndrome (ds) (ml-ds), and both are related to gata1 pathogenic variants. |
2021-06-08 |
2023-08-13 |
Not clear |
| Wenbo Ma, Yanna Liu, Jingbin Ya. [Genome-wide analysis of aberrant DNA methylation patterns in iPSCs derived from patients with Down syndrome]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 38. issue 6. 2021-06-08. PMID:34096019. |
to study the correlation between dna methylation patterns and gene expression in down syndrome (ds). |
2021-06-08 |
2023-08-13 |
Not clear |
| Genki Yamato, Myoung-Ja Park, Manabu Sotomatsu, Taeko Kaburagi, Kenichi Maruyama, Tomio Kobayashi, Akira Nishi, Kiyoko Sameshima, Kentaro Ohki, Yasuhide Hayash. Clinical features of 35 Down syndrome patients with transient abnormal myelopoiesis at a single institution. International journal of hematology. vol 113. issue 5. 2021-06-07. PMID:33394336. |
transient abnormal myelopoiesis (tam) is a unique clonal myeloproliferation characterized by immature megakaryoblasts that occurs in 5-10% of neonates with down syndrome (ds). |
2021-06-07 |
2023-08-13 |
Not clear |
| H Diana Rosas, Eugene Hsu, Nathaniel D Mercaldo, Florence Lai, Margaret Pulsifer, David Keator, Adam M Brickman, Julie Price, Michael Yassa, Christy Hom, Sharon J Krinsky-McHale, Wayne Silverman, Ira Lott, Nicole Schup. Alzheimer-related altered white matter microstructural integrity in Down syndrome: A model for sporadic AD? Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-06-04. PMID:33204811. |
virtually all adults with down syndrome (ds) develop alzheimer's disease (ad)-associated neuropathology by the age of 40, with risk for dementia increasing from the early 50s. |
2021-06-04 |
2023-08-13 |
Not clear |
| Matthew D Zammit, Charles M Laymon, Dana L Tudorascu, Sigan L Hartley, Brianna Piro-Gambetti, Sterling C Johnson, Charles K Stone, Chester A Mathis, Shahid H Zaman, William E Klunk, Benjamin L Handen, Ann D Cohen, Bradley T Christia. Patterns of glucose hypometabolism in Down syndrome resemble sporadic Alzheimer's disease except for the putamen. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-06-04. PMID:33490360. |
adults with down syndrome (ds) are predisposed to alzheimer's disease (ad) and the relationship between cognition and glucose metabolism in this population has yet to be evaluated. |
2021-06-04 |
2023-08-13 |
Not clear |
| Arnaud Duchon, Maria Del Mar Muniz Moreno, Sandra Martin Lorenzo, Marcia Priscilla Silva de Souza, Claire Chevalier, Valérie Nalesso, Hamid Meziane, Paulo Loureiro de Sousa, Vincent Noblet, Jean-Paul Armspach, Veronique Brault, Yann Heraul. Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models. Human molecular genetics. vol 30. issue 9. 2021-06-04. PMID:33693642. |
down syndrome (ds) is the most common genetic form of intellectual disability caused by the presence of an additional copy of human chromosome 21 (hsa21). |
2021-06-04 |
2023-08-13 |
mouse |
| Jeanhee Chung, Karen Donelan, Eric A Macklin, Alison Schwartz, Ibrahim Elsharkawi, Amy Torres, Yichuan Grace Hsieh, Holly Parker, Stephen Lorenz, Vasiliki Patsiogiannis, Stephanie L Santoro, Mark Wylie, Lloyd Clarke, Greg Estey, Sandra Baker, Patricia E Bauer, Marilyn Bull, Brian Chicoine, Sarah Cullen, Ariel Frey-Vogel, Maureen Gallagher, Reem Hasan, Ashley Lamb, Lisa Majewski, Jawanda Mast, Travis Riddell, Karen Sepucha, Melissa Skavlem, Brian G Skotk. A randomized controlled trial of an online health tool about Down syndrome. Genetics in medicine : official journal of the American College of Medical Genetics. vol 23. issue 1. 2021-06-03. PMID:32879436. |
we sought to determine if a novel online health tool, called down syndrome clinic to you (dsc2u), could improve adherence to national down syndrome (ds) guidelines. |
2021-06-03 |
2023-08-13 |
Not clear |
| Loora Laan, Joakim Klar, Maria Sobol, Jan Hoeber, Mansoureh Shahsavani, Malin Kele, Ambrin Fatima, Muhammad Zakaria, Göran Annerén, Anna Falk, Jens Schuster, Niklas Dah. DNA methylation changes in Down syndrome derived neural iPSCs uncover co-dysregulation of ZNF and HOX3 families of transcription factors. Clinical epigenetics. vol 12. issue 1. 2021-06-02. PMID:31915063. |
down syndrome (ds) is characterized by neurodevelopmental abnormalities caused by partial or complete trisomy of human chromosome 21 (t21). |
2021-06-02 |
2023-08-13 |
human |
| Julie C Lauterborn, Pietro Scaduto, Conor D Cox, Anton Schulmann, Gary Lynch, Christine M Gall, C Dirk Keene, Agenor Limo. Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer's disease. Nature communications. vol 12. issue 1. 2021-06-02. PMID:33972518. |
we assessed anatomical and electrophysiological synaptic e/i ratios in post-mortem parietal cortex samples from middle-aged individuals with ad (early-onset) or down syndrome (ds) by fluorescence deconvolution tomography and microtransplantation of synaptic membranes. |
2021-06-02 |
2023-08-13 |
Not clear |