| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mitsuhiro Masaki, Karin Sugawara, Yuka Iizuka, Yuki Uchikawa, Honoka Isobe, Fuyumi Hattori, Koki Mano, Keiko Saito, Ayaka Sugino, Kana Kato, Kenji Sakain. Comparison of the degree of pes planovalgus and muscle mass of the ankle joint and foot muscles between children with Down syndrome and children with typical development. Journal of biomechanics. vol 122. 2021-07-07. PMID:33932916. |
we aimed to compare the degree of pes planovalgus and muscle mass of the ankle joint and foot muscles between children with down syndrome (ds) and children with typical development (td). |
2021-07-07 |
2023-08-13 |
human |
| Christy R Sibarani, Lisa M Walter, Margot J Davey, Gillian M Nixon, Rosemary S C Horn. Sleep-disordered breathing and sleep macro- and micro-architecture in children with Down syndrome. Pediatric research. 2021-07-07. PMID:34230620. |
children with down syndrome (ds) are at increased risk of sleep-disordered breathing (sdb), which is associated with intermittent hypoxia and sleep disruption affecting daytime functioning. |
2021-07-07 |
2023-08-13 |
Not clear |
| Sarah E Lee, Monica Duran-Martinez, Sabina Khantsis, Diana W Bianchi, Faycal Gued. Challenges and Opportunities for Translation of Therapies to Improve Cognition in Down Syndrome. Trends in molecular medicine. vol 26. issue 2. 2021-07-06. PMID:31706840. |
while preclinical studies have reported improvement of behavioral deficits in the ts65dn mouse model of down syndrome (ds), translation to human clinical trials to improve cognition in individuals with ds has had a poor success record. |
2021-07-06 |
2023-08-13 |
mouse |
| Hong-Guo Zhang, Yu-Ting Jiang, Si-Da Dai, Ling Li, Xiao-Nan Hu, Rui-Zhi Li. Application of intelligent algorithms in Down syndrome screening during second trimester pregnancy. World journal of clinical cases. vol 9. issue 18. 2021-07-06. PMID:34222424. |
down syndrome (ds) is one of the most common chromosomal aneuploidy diseases. |
2021-07-06 |
2023-08-13 |
Not clear |
| Blandine Ponroy Bally, W Todd Farmer, Emma V Jones, Selin Jessa, J Benjamin Kacerovsky, Alexandre Mayran, Huashan Peng, Julie L Lefebvre, Jacques Drouin, Arnold Hayer, Carl Ernst, Keith K Mura. Human iPSC-derived Down syndrome astrocytes display genome-wide perturbations in gene expression, an altered adhesion profile, and increased cellular dynamics. Human molecular genetics. vol 29. issue 5. 2021-07-05. PMID:31943018. |
down syndrome (ds), caused by the triplication of human chromosome 21, leads to significant alterations in brain development and is a major genetic cause of intellectual disability. |
2021-07-05 |
2023-08-13 |
human |
| Masato Takeuchi, Koji Kawakam. Universal palivizumab prophylaxis for children with Down syndrome in Japan: analysis with interrupted time-series. Human vaccines & immunotherapeutics. vol 17. issue 4. 2021-07-05. PMID:32961094. |
down syndrome (ds) is an independent risk factor for severe respiratory syncytial virus (rsv) infection. |
2021-07-05 |
2023-08-13 |
Not clear |
| Jonathan D Santoro, Justin Del Rosario, Beth Osterbauer, Emily S Gillett, Debra M Do. Sleep positions in children with Down syndrome and obstructive sleep apnea. Sleep medicine. vol 81. 2021-07-05. PMID:33865077. |
to assess sleep positions in children with both down syndrome (ds) and obstructive sleep apnea (osa) and determine if there is a preferred sleep position by severity of apnea. |
2021-07-05 |
2023-08-13 |
Not clear |
| Ahmad Bassam, Julie Thacker, Lisa M Walter, Margot J Davey, Gillian M Nixon, Rosemary Sc Horn. Nocturnal dipping of heart rate is impaired in children with Down syndrome and sleep disordered breathing. Sleep medicine. vol 81. 2021-07-05. PMID:33872947. |
children with down syndrome (ds) are at increased risk for sleep disordered breathing (sdb), which can have adverse effects on the cardiovascular system. |
2021-07-05 |
2023-08-13 |
Not clear |
| Poornima R Wijayaratne, Katrina Williams, Margot J Davey, Rosemary S C Horne, Gillian M Nixo. Factors associated with referral for polysomnography in children with Down syndrome. Sleep medicine. vol 82. 2021-07-05. PMID:33878521. |
children with down syndrome (ds) are recommended to undergo polysomnography (psg) by the age of four years due to the high prevalence of obstructive sleep apnea (osa) in this group, but compliance is incomplete. |
2021-07-05 |
2023-08-13 |
Not clear |
| Po-Yang Tsou, Christopher M Cielo, Melissa S Xanthopoulos, Yu-Hsun Wang, Pei-Lun Kuo, Ignacio E Tapi. The impact of obstructive sleep apnea on bronchiolitis severity in children with Down syndrome. Sleep medicine. vol 83. 2021-07-05. PMID:34022496. |
acute bronchiolitis commonly causes respiratory failure in children ≤2 years, and is particularly severe in those with down syndrome (ds). |
2021-07-05 |
2023-08-13 |
Not clear |
| G Regaieg, G Kermarrec, S Sahl. Designed game situations enhance fundamental movement skills in children with Down syndrome. Journal of intellectual disability research : JIDR. vol 64. issue 4. 2021-07-02. PMID:31994262. |
this study aimed to compare the effects of a designed program based on games situations with those of a conventional one, the adapted physical education (ape) program, on the fundamental movement skills (fms) in children with down syndrome (ds), aged 6 to 10. |
2021-07-02 |
2023-08-13 |
Not clear |
| Caitlin Menzies, Shama Naz, David Patten, Thierry Alquier, Brian M Bennett, Baptiste Lacost. Distinct Basal Metabolism in Three Mouse Models of Neurodevelopmental Disorders. eNeuro. vol 8. issue 2. 2021-07-02. PMID:33820803. |
here, we present the first characterization and comparison of basal metabolism in three mouse models of ndds, namely, down syndrome (ds; |
2021-07-02 |
2023-08-13 |
mouse |
| Borja Suarez-Villadat, Ariel Villagra, Oscar L Veiga, Veronica Cabanas-Sanchez, Rocio Izquierdo-Gomez, On Behalf Of The Up Down Study Grou. Prospective Associations of Physical Activity and Health-Related Physical Fitness in Adolescents with Down Syndrome: The UP&DOWN Longitudinal Study. International journal of environmental research and public health. vol 18. issue 11. 2021-07-02. PMID:34063942. |
however, research on the association between pa and health-related physical fitness in adolescents with ds (down syndrome) is limited, and most of the previous studies have been developed with a cross-sectional perspective. |
2021-07-02 |
2023-08-13 |
human |
| Adriano L Roque, Mark W Johnson, Melissa R Stasko, Luiz C de Abreu, Talita D da Silva, Alberto C S Cost. Noninvasive assessment of autonomic modulation of heart rate variability in the Ts65Dn mouse model of Down syndrome: A proof of principle study. Physiological reports. vol 8. issue 12. 2021-07-01. PMID:32562388. |
the ts65dn mouse is the most widely used animal model of down syndrome (ds). |
2021-07-01 |
2023-08-13 |
mouse |
| Narges Vali Noghondar, Mehdi Sohrabi, Hamid Reza Taheri, Hamid Reza Kobravi, Ezzat Khodashena. Pre-programming in overhand throwing of children with Down syndrome: role of the generalized motor program. International journal of developmental disabilities. vol 67. issue 3. 2021-07-01. PMID:34188902. |
it is unclear whether slowness and higher reaction time of individuals with down syndrome (ds) are because of inability to pre-program and using the generalized motor program (gmp) or not. |
2021-07-01 |
2023-08-13 |
Not clear |
| Audrée Gareau-Léonard, Alexandre Fillion, Laurence Labine, Cédric Gasse, Suzanne Demers, Emmanuel Bujol. Evolution of Down Syndrome Prenatal Screening Clinical Practices in Québec. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC. vol 42. issue 4. 2021-06-30. PMID:32001179. |
prenatal screening for down syndrome (ds) has evolved greatly over the last decades with the improvement of first- and second-trimester serum screening and the introduction of cell-free fetal dna. |
2021-06-30 |
2023-08-13 |
Not clear |
| María Dolores Figueroa-Jimenez, Cristina Cañete-Massé, María Carbó-Carreté, Daniel Zarabozo-Hurtado, Maribel Peró-Cebollero, José Guadalupe Salazar-Estrada, Joan Guàrdia-Olmo. Resting-state default mode network connectivity in young individuals with Down syndrome. Brain and behavior. vol 11. issue 1. 2021-06-30. PMID:33179859. |
down syndrome (ds) is a chromosomal disorder that causes intellectual disability. |
2021-06-30 |
2023-08-13 |
Not clear |
| Megan K Gautier, Stephen D Ginsber. A method for quantification of vesicular compartments within cells using 3D reconstructed confocal z-stacks: Comparison of ImageJ and Imaris to count early endosomes within basal forebrain cholinergic neurons. Journal of neuroscience methods. vol 350. 2021-06-30. PMID:33338543. |
for example, accurate assessment of early endosome pathology is crucial to the study of down syndrome (ds) and alzheimer's disease (ad), as well as other neurological disorders with endosomal-lysosomal pathology. |
2021-06-30 |
2023-08-13 |
Not clear |
| Marie Moore Channel. The Social Responsiveness Scale (SRS-2) in school-age children with Down syndrome at low risk for autism spectrum disorder. Autism & developmental language impairments. vol 5. 2021-06-30. PMID:34179506. |
little is known about how autism spectrum disorder (asd) symptoms present in individuals with down syndrome (ds). |
2021-06-30 |
2023-08-13 |
Not clear |
| Camino Fernández-Alcaraz, Fernando Carvaja. Neuropsychological profile of adults with Down syndrome and moderate intellectual disability. Research in developmental disabilities. vol 107. 2021-06-29. PMID:33017785. |
the neuropsychological profile of individuals with down syndrome (ds) has been described as being characterized by dissociations between verbal and visual abilities, as well as between verbal comprehension and production abilities (higher visual than verbal abilities and higher verbal comprehension than verbal production abilities). |
2021-06-29 |
2023-08-13 |
Not clear |