| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Young Bae Choi, Keon Hee Yo. Epidemiology of Acute Leukemia among Children with Down Syndrome in Korea. Cancer research and treatment. 2021-08-12. PMID:34384014. |
children with down syndrome (ds) show a higher risk of acute leukemia than those without ds. |
2021-08-12 |
2023-08-13 |
Not clear |
| Alicja Naczk, Ewa Gajewska, Mariusz Nacz. Effectiveness of Swimming Program in Adolescents with Down Syndrome. International journal of environmental research and public health. vol 18. issue 14. 2021-08-11. PMID:34299891. |
the aim of this study was to estimate the influence of a 33-week swimming program on aerobic capacity, muscle strength, balance, flexibility, and body composition of adolescents with down syndrome (ds). |
2021-08-11 |
2023-08-13 |
Not clear |
| Laszlo Pecze, Elisa B Randi, Csaba Szab. Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome. Molecular medicine (Cambridge, Mass.). vol 26. issue 1. 2021-08-10. PMID:33167881. |
clinical observations and preclinical studies both suggest that down syndrome (ds) may be associated with significant metabolic and bioenergetic alterations. |
2021-08-10 |
2023-08-13 |
human |
| Tomer Illouz, Raneen Nicola, Linoy Ben-Shushan, Ravit Madar, Arya Biragyn, Eitan Oku. Maternal antibodies facilitate Amyloid-β clearance by activating Fc-receptor-Syk-mediated phagocytosis. Communications biology. vol 4. issue 1. 2021-08-10. PMID:33712740. |
maternally transferred immunity may also be harnessed to target diseases associated with endogenous protein misfolding and aggregation, such as alzheimer's disease (ad) and ad-pathology in down syndrome (ds). |
2021-08-10 |
2023-08-13 |
mouse |
| Tomohiko Nishino, Shota Endo, Hiroki Miyano, Yoichi Takemasa, Masahito Saito, Chisato Umeda, Yuji Tomii, Yoshitaka Watanabe, Mayu Nakagawa, Daisuke Kakegawa, Shuichiro Fujinag. Reference serum creatinine levels according to sex, age, and height in children with Down syndrome. European journal of pediatrics. vol 180. issue 9. 2021-08-10. PMID:33860353. |
however, it is unclear if this fluctuation in s-cr levels is present for children with down syndrome (ds) who show atypical growth rate. |
2021-08-10 |
2023-08-13 |
Not clear |
| Keiji Kawatani, Toshihiko Nambara, Nobutoshi Nawa, Hidetaka Yoshimatsu, Haruna Kusakabe, Katsuya Hirata, Akira Tanave, Kenta Sumiyama, Kimihiko Banno, Hidetoshi Taniguchi, Hitomi Arahori, Keiichi Ozono, Yasuji Kitabatak. A human isogenic iPSC-derived cell line panel identifies major regulators of aberrant astrocyte proliferation in Down syndrome. Communications biology. vol 4. issue 1. 2021-08-10. PMID:34127780. |
astrocytes exert adverse effects on the brains of individuals with down syndrome (ds). |
2021-08-10 |
2023-08-13 |
human |
| David G Moreno, Emma C Utagawa, Nicoleta C Arva, Kristian T Schafernak, Elliott J Mufson, Sylvia E Pere. Postnatal Cytoarchitecture and Neurochemical Hippocampal Dysfunction in Down Syndrome. Journal of clinical medicine. vol 10. issue 15. 2021-08-10. PMID:34362198. |
although the prenatal hippocampus displays deficits in cellular proliferation/migration and volume, which are later associated with memory deficits, little is known about the effects of trisomy 21 on postnatal hippocampal cellular development in down syndrome (ds). |
2021-08-10 |
2023-08-13 |
Not clear |
| Stephanie L Santoro, Ashlee Campbell, Clorinda Cottrell, Karen Donelan, Ben Majewski, Nicolas M Oreskovic, Vasiliki Patsiogiannis, Amy Torres, Brian G Skotk. Piloting the use of global health measures in a Down syndrome clinic. Journal of applied research in intellectual disabilities : JARID. vol 34. issue 4. 2021-08-09. PMID:33759305. |
people with down syndrome (ds) have a unique medical profile which may impact views of health. |
2021-08-09 |
2023-08-13 |
Not clear |
| Jovana Pejovic, Marisa Cruz, Cátia Severino, Sónia Frot. Early Visual Attention Abilities and Audiovisual Speech Processing in 5-7 Month-Old Down Syndrome and Typically Developing Infants. Brain sciences. vol 11. issue 7. 2021-08-09. PMID:34356172. |
communicative abilities in infants with down syndrome (ds) are delayed in comparison to typically developing (td) infants, possibly affecting language development in ds. |
2021-08-09 |
2023-08-13 |
Not clear |
| K Kristensen, K M Lorenz, X Zhou, B Piro-Gambetti, S L Hartley, S P Godar, S Diel, E Neubauer, R Y Litovsk. Language and executive functioning in young adults with Down syndrome. Journal of intellectual disability research : JIDR. 2021-08-06. PMID:34288180. |
this study examined the association between executive functioning and language in young adults with down syndrome (ds). |
2021-08-06 |
2023-08-13 |
Not clear |
| Giorgio Ottaviano, Jolanda Gerosa, Micaela Santini, Pasqualina De Leo, Andrea Vecchione, Tatiana Jofra, Cristiana Trimarchi, Maurizio De Pellegrin, Massimo Agosti, Alessandro Aiuti, Maddalena Marinoni, Maria Pia Cicalese, Georgia Fouster. A Prevalent CXCR3 Journal of clinical immunology. vol 40. issue 3. 2021-08-04. PMID:31993866. |
a prevalent cxcr3 patients with down syndrome (ds) are characterized by increased susceptibility to autoimmunity and respiratory tract infections that are suggestive of humoral immunity impairment. |
2021-08-04 |
2023-08-13 |
Not clear |
| Lajos Csincsik, Rachel Nelson, Madeleine J Walpert, Tunde Peto, Anthony Holland, Imre Lengye. Increased choroidal thickness in adults with Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands). vol 13. issue 1. 2021-08-03. PMID:33748396. |
people with down syndrome (ds) are particularly susceptible to alzheimer's disease (ad) due to the triplication of the amyloid precursor protein ( |
2021-08-03 |
2023-08-13 |
Not clear |
| Lars H Breime. Non-invasive prenatal testing: Special interest groups vs women's autonomy. Indian journal of medical ethics. vol V. issue 4. 2021-08-03. PMID:34018960. |
non-invasive prenatal testing (nipt) is moving the goalposts for the detection of genetic disorders such as down syndrome (ds). |
2021-08-03 |
2023-08-13 |
Not clear |
| Douglas Bush, Csaba Galambos, David Dunbar Iv. Pulmonary hypertension in children with Down syndrome. Pediatric pulmonology. vol 56. issue 3. 2021-08-02. PMID:32049444. |
individuals with down syndrome (ds) have an increased risk of developing pulmonary hypertension (ph). |
2021-08-02 |
2023-08-13 |
Not clear |
| Octavio O Santos-Neto, Marina H Mariano, Antonia P Marques-de-Faria, Juliana G R Andrade, Tarsis A P Vieira, Nilma L Viguetti-Campos, Ana P Dos Santos, Maricilda P Mello, Tais N Mazzola, Mara S Guaragna, Helena Fabbri-Scallet, Durval Damiani, Leandra Steinmetz, Marianna R Ferreira, Paula A Saito, Jean C Sievert, Andrea T Maciel-Guerra, Gil Guerra-Junio. Association between Down Syndrome and Disorders of Sex Development: Report of Three Cases and Review of 188 Cases in the Literature. Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. vol 14. issue 1-6. 2021-08-02. PMID:33652437. |
in this study, we present 3 cases of down syndrome (ds) associated with disorders/differences of sex development (dsd) and review the literature on this topic. |
2021-08-02 |
2023-08-13 |
Not clear |
| Tomer Illouz, Arya Biragyn, Maria Florencia Iulita, Lisi Flores-Aguilar, Mara Dierssen, Ilario De Toma, Stylianos E Antonarakis, Eugene Yu, Yann Herault, Marie-Claude Potier, Alexandra Botté, Randall Roper, Benjamin Sredni, Jacqueline London, William Mobley, Andre Strydom, Eitan Oku. Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome. Frontiers in immunology. vol 12. 2021-08-02. PMID:34248930. |
down syndrome (ds), the most prevalent intellectual disability, is caused by trisomy-21 in ~1:750 live births worldwide. |
2021-08-02 |
2023-08-13 |
Not clear |
| Ilaria Zuliani, Chiara Lanzillotta, Antonella Tramutola, Antonio Francioso, Sara Pagnotta, Eugenio Barone, Marzia Perluigi, Fabio Di Domenic. The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 18. issue 1. 2021-07-30. PMID:33258073. |
down syndrome (ds) individuals are characterized by the early development of ad by the age of 60 and, although the two conditions present the same pathological hallmarks and share the alteration of many molecular mechanisms driving brain degeneration, no evidence has been sought on the implication of o-glcnacylation in ds pathology. |
2021-07-30 |
2023-08-13 |
Not clear |
| Randall J Roper, Charles R Goodlett, María Martínez de Lagrán, Mara Diersse. Behavioral Phenotyping for Down Syndrome in Mice. Current protocols in mouse biology. vol 10. issue 3. 2021-07-29. PMID:32780566. |
down syndrome (ds) is the most frequent genetic cause of intellectual disability, characterized by alterations in different behavioral symptom domains: neurodevelopment, motor behavior, and cognition. |
2021-07-29 |
2023-08-13 |
mouse |
| Michele Salemi, Rossella Cannarella, Giovanna Marchese, Maria Grazia Salluzzo, Maria Ravo, Concetta Barone, Angela Cordella, Salvatore Caniglia, Roberto Castiglione, Alda Ragalmuto, Aldo E Calogero, Corrado Roman. CCR3 gene overexpression in patients with Down syndrome. Molecular biology reports. vol 48. issue 6. 2021-07-29. PMID:34184200. |
chromosome 21 trisomy or down syndrome (ds) is the most common genetic cause of intellectual disability (id). |
2021-07-29 |
2023-08-13 |
Not clear |
| Sandra Giménez, Miren Altuna, Esther Blessing, Ricardo M Osorio, Juan Forte. Sleep Disorders in Adults with Down Syndrome. Journal of clinical medicine. vol 10. issue 14. 2021-07-29. PMID:34300177. |
sleep disorders, despite being very frequent in adults with down syndrome (ds), are often overlooked due to a lack of awareness by families and physicians and the absence of specific clinical sleep guidelines. |
2021-07-29 |
2023-08-13 |
Not clear |