| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L T Ptomey, D L Walpitage, M Mohseni, M L Dreyer Gillette, A M Davis, B Forseth, E E Dean, L R Waitma. Weight status and associated comorbidities in children and adults with Down syndrome, autism spectrum disorder and intellectual and developmental disabilities. Journal of intellectual disability research : JIDR. vol 64. issue 9. 2021-09-01. PMID:32716138. |
little is known about body weight status and the association between body weight and common comorbidities in children and adults with down syndrome (ds), autism spectrum disorder (asd) and other intellectual and developmental disabilities (idds). |
2021-09-01 |
2023-08-13 |
Not clear |
| Christina M Hospodar, Andrina Sabet, Samuel W Logan, Michele A Catena, James C Gallowa. Exploratory analysis of a developmentally progressive modified ride-on car intervention for young children with Down syndrome. Disability and rehabilitation. Assistive technology. vol 16. issue 7. 2021-08-31. PMID:31939311. |
children with down syndrome (ds) may have limited opportunities to engage in self-directed mobility and play due to motor delays. |
2021-08-31 |
2023-08-13 |
Not clear |
| F de Campos Gomes, J S de Melo-Neto, E M Goloni-Bertollo, É C Pavarin. Trends and predictions for survival and mortality in individuals with Down syndrome in Brazil: A 21-year analysis. Journal of intellectual disability research : JIDR. vol 64. issue 7. 2021-08-31. PMID:32378275. |
however, for individuals with down syndrome (ds) this information remains unknown. |
2021-08-31 |
2023-08-13 |
Not clear |
| Michael S Schimmel, Francis B Mimouni, Tali Mor Yosef, Netanel Wassertei. "Your baby has Down syndrome": what is the preferable way to inform parents? Journal of perinatology : official journal of the California Perinatal Association. vol 40. issue 8. 2021-08-31. PMID:32488038. |
we tested whether mothers of neonates with down syndrome (ds) prefer to get the diagnosis after delivery in a one-step approach or in a two-step one (information about suggestive findings, followed by additional explicit meeting). |
2021-08-31 |
2023-08-13 |
Not clear |
| Joyce J Mathan, Akilesh Gokul, Samantha K Simkin, Jay J Meyer, Dipika V Patel, Charles N J McGhe. Topographic screening reveals keratoconus to be extremely common in Down syndrome. Clinical & experimental ophthalmology. vol 48. issue 9. 2021-08-31. PMID:32876978. |
keratoconus disproportionately affects people with down syndrome (ds). |
2021-08-31 |
2023-08-13 |
Not clear |
| Anna J Moyer, Katheleen Gardiner, Roger H Reeve. All Creatures Great and Small: New Approaches for Understanding Down Syndrome Genetics. Trends in genetics : TIG. vol 37. issue 5. 2021-08-31. PMID:33097276. |
the ultimate goal of down syndrome (ds) research is to design therapies that improve quality of life for individuals with ds by understanding which subsets of hsa21 genes contribute to ds-associated phenotypes throughout the lifetime. |
2021-08-31 |
2023-08-13 |
human |
| Laia Montoliu-Gaya, Andre Strydom, Kaj Blennow, Henrik Zetterberg, Nicholas James Ashto. Blood Biomarkers for Alzheimer's Disease in Down Syndrome. Journal of clinical medicine. vol 10. issue 16. 2021-08-31. PMID:34441934. |
epidemiological evidence suggests that by the age of 40 years, all individuals with down syndrome (ds) have alzheimer's disease (ad) neuropathology. |
2021-08-31 |
2023-08-13 |
Not clear |
| Diego Real de Asua, Miguel A Mayer, María Del Carmen Ortega, Jose M Borrel, Teresa de Jesús Bermejo, Domingo González-Lamuño, Coral Manso, Fernando Moldenhauer, María Carmona-Iragui, Anke Hüls, Stephanie L Sherman, Andre Strydom, Rafael de la Torre, Mara Diersse. Comparison of COVID-19 and Non-COVID-19 Pneumonia in Down Syndrome. Journal of clinical medicine. vol 10. issue 16. 2021-08-31. PMID:34442043. |
whether the increased risk for coronavirus disease 2019 (covid-19) hospitalization and death observed in down syndrome (ds) are disease specific or also occur in individuals with ds and non-covid-19 pneumonias is unknown. |
2021-08-31 |
2023-08-13 |
Not clear |
| Lourdes Gutiérrez-Vilahú, Myriam Guerra-Bali. Footprint measurement methods for the assessment and classification of foot types in subjects with Down syndrome: a systematic review. Journal of orthopaedic surgery and research. vol 16. issue 1. 2021-08-31. PMID:34452620. |
musculoskeletal disorders, especially in the feet, are common in people with down syndrome (ds). |
2021-08-31 |
2023-08-13 |
human |
| A Claudio Cuell. Rita Levi-Montalcini, NGF Metabolism in Health and in the Alzheimer's Pathology. Advances in experimental medicine and biology. vol 1331. 2021-08-31. PMID:34453296. |
the findings of a deregulation of the ngf metabolic pathway and its reflection in plasma and csf are opening doors for the development of novel biomarkers for preclinical detection of ad pathology both in alzheimer's and in down syndrome (ds) with "silent" ad pathology. |
2021-08-31 |
2023-08-13 |
Not clear |
| Melissa Petersen, Fan Zhang, Sharon J Krinsky-McHale, Wayne Silverman, Joseph H Lee, Deborah Pang, James Hall, Nicole Schupf, Sid E O'Bryan. Proteomic profiles of prevalent mild cognitive impairment and Alzheimer's disease among adults with Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-08-30. PMID:32435687. |
we sought to determine if a proteomic profile approach developed to detect alzheimer's disease (ad) in the general population would apply to adults with down syndrome (ds). |
2021-08-30 |
2023-08-13 |
Not clear |
| Sid E O'Bryant, Fan Zhang, Wayne Silverman, Joseph H Lee, Sharon J Krinsky-McHale, Deborah Pang, James Hall, Nicole Schup. Proteomic profiles of incident mild cognitive impairment and Alzheimer's disease among adults with Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-08-30. PMID:32490140. |
we sought to determine if proteomic profiles could predict risk for incident mild cognitive impairment (mci) and alzheimer's disease (ad) among adults with down syndrome (ds). |
2021-08-30 |
2023-08-13 |
Not clear |
| D Valentini, C Di Camillo, N Mirante, G Vallogini, N Olivini, A Baban, L Buzzonetti, A Galeotti, M Raponi, A Villan. Medical conditions of children and young people with Down syndrome. Journal of intellectual disability research : JIDR. vol 65. issue 2. 2021-08-30. PMID:33426738. |
the life expectancy of people with down syndrome (ds) has significantly increased in the last decades. |
2021-08-30 |
2023-08-13 |
Not clear |
| Alba de la Torre Carril, Montserrat Durán-Bouza, Miguel Pérez-Pereir. Capacity of the CCC-2 to Discriminate ASD from Other Neurodevelopmental Disorders. Children (Basel, Switzerland). vol 8. issue 8. 2021-08-30. PMID:34438530. |
the sample is of 117 children previously diagnosed with different disorders: autism spectrum disorder (asd), developmental language disorder (dld), attention deficit with hyperactivity disorder (adhd), down syndrome children (ds) and typically developing children (td). |
2021-08-30 |
2023-08-13 |
Not clear |
| Mariska De Lausnay, Stijn Verhulst, Kim Van Hoorenbeeck, An Boudewyn. Obstructive Sleep Disorders in Down Syndrome's Children with and without Lower Airway Anomalies. Children (Basel, Switzerland). vol 8. issue 8. 2021-08-30. PMID:34438584. |
(1) background: obstructive sleep apnea (osa) and lower airway anomalies are both highly prevalent in children with down syndrome (ds). |
2021-08-30 |
2023-08-13 |
Not clear |
| Carini Picardi Morais de Castro, Maria Cadefau, Sergi Cuarter. The Mutational Landscape of Myeloid Leukaemia in Down Syndrome. Cancers. vol 13. issue 16. 2021-08-30. PMID:34439298. |
children with down syndrome (ds) are particularly prone to haematopoietic disorders. |
2021-08-30 |
2023-08-13 |
Not clear |
| Kavita Krell, Kelsey Haugen, Amy Torres, Stephanie L Santor. Description of Daily Living Skills and Independence: A Cohort from a Multidisciplinary Down Syndrome Clinic. Brain sciences. vol 11. issue 8. 2021-08-30. PMID:34439631. |
levels of independence vary in individuals with down syndrome (ds). |
2021-08-30 |
2023-08-13 |
Not clear |
| Benjamin Handen, Isabel Clare, Charles Laymon, Melissa Petersen, Shahid Zaman, Sid O'Bryant, Davneet Minhas, Dana Tudorascu, Stephanie Brown, Bradley Christia. Acute Regression in Down Syndrome. Brain sciences. vol 11. issue 8. 2021-08-30. PMID:34439728. |
acute regression has been reported in some individuals with down syndrome (ds), typically occurring between the teenage years and mid to late 20s. |
2021-08-30 |
2023-08-13 |
Not clear |
| Anke Hüls, Alberto C S Costa, Mara Dierssen, R Asaad Baksh, Stefania Bargagna, Nicole T Baumer, Ana Claudia Brandão, Angelo Carfi, Maria Carmona-Iragui, Brian Allen Chicoine, Sujay Ghosh, Monica Lakhanpaul, Coral Manso, Miguel-Angel Mayer, Maria Del Carmen Ortega, Diego Real de Asua, Anne-Sophie Rebillat, Lauren Ashley Russell, Giuseppina Sgandurra, Diletta Valentini, Stephanie L Sherman, Andre Strydo. Medical vulnerability of individuals with Down syndrome to severe COVID-19-data from the Trisomy 21 Research Society and the UK ISARIC4C survey. EClinicalMedicine. vol 33. 2021-08-29. PMID:33644721. |
health conditions, immune dysfunction, and premature aging associated with trisomy 21 (down syndrome, ds) may impact the clinical course of covid-19. |
2021-08-29 |
2023-08-13 |
Not clear |
| Sonia Do Carmo, Benjamin Kannel, A Claudio Cuell. Nerve Growth Factor Compromise in Down Syndrome. Frontiers in aging neuroscience. vol 13. 2021-08-27. PMID:34434101. |
here, we present a brief overview of the characteristics of alzheimer's pathology in down syndrome (ds) with an emphasis on this ngf metabolic pathway's disruption during the evolving alzheimer's pathology. |
2021-08-27 |
2023-08-13 |
Not clear |