| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Olivia Belbin, Mei-Fang Xiao, Desheng Xu, Maria Carmona-Iragui, Jordi Pegueroles, Bessy Benejam, Laura Videla, Susana Fernández, Isabel Barroeta, Raúl Nuñez-Llaves, Victor Montal, Eduard Vilaplana, Miren Altuna, Jordi Clarimón, Daniel Alcolea, Rafael Blesa, Alberto Lleó, Paul F Worley, Juan Forte. Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer's disease-related inhibitory circuit dysfunction in adults with Down syndrome. Molecular neurodegeneration. vol 15. issue 1. 2021-08-26. PMID:32807227. |
alzheimer's disease (ad) is the major cause of death in adults with down syndrome (ds). |
2021-08-26 |
2023-08-13 |
Not clear |
| Zhaowei Cai, Zhilan Xiao, Yufang Wang, Huazhen Liu, Kangdi Zhang, Xiaoning Zhen, Xiaoling Jian. Comparative analysis of the down syndrome hippocampal non-coding RNA transcriptomes using a mouse model. Genes & genomics. vol 42. issue 11. 2021-08-26. PMID:32946063. |
down syndrome (ds), caused by trisomy 21, is the most common human chromosomal disorder. |
2021-08-26 |
2023-08-13 |
mouse |
| Angela John Thurman, Jamie O Edgin, Stephanie L Sherman, Audra Sterling, Andrea McDuffie, Elizabeth Berry-Kravis, Debra Hamilton, Leonard Abbedut. Spoken language outcome measures for treatment studies in Down syndrome: feasibility, practice effects, test-retest reliability, and construct validity of variables generated from expressive language sampling. Journal of neurodevelopmental disorders. vol 13. issue 1. 2021-08-26. PMID:33827417. |
the purpose of this study was to evaluate expressive language sampling (els) as a procedure for generating spoken language outcome measures for treatment research in down syndrome (ds). |
2021-08-26 |
2023-08-13 |
Not clear |
| Mariska De Lausnay, Stijn Verhulst, Lieve Boel, Kim Van Hoorenbeec. Lower airway microbiota in children with Down syndrome compared to controls with similar respiratory symptomatology. Translational pediatrics. vol 10. issue 7. 2021-08-26. PMID:34430429. |
children with down syndrome (ds) often present with chronic or recurrent respiratory symptoms and generally have a more severe and prolonged disease course in case of infection. |
2021-08-26 |
2023-08-13 |
Not clear |
| Jung-Hyun Kim, Liping Li, Linda Ms Resa. Doubling up on function: dual-specificity tyrosine-regulated kinase 1A (DYRK1A) in B cell acute lymphoblastic leukemia. The Journal of clinical investigation. vol 131. issue 1. 2021-08-25. PMID:33393492. |
bhansali, rammohan, and colleagues investigated b cell acute lymphoblastic leukemia (b-all) in individuals with down syndrome (ds) and in children with leukemia characterized by aneuploidy. |
2021-08-25 |
2023-08-13 |
Not clear |
| Hamid Reza Farpour, Seyed Ali Moosavi, Zhila Mohammadian, Sima Farpou. Comparing the Tongue and Lip Strength and Endurance of Children with Down Syndrome with Their Typical Peers Using IOPI. Dysphagia. 2021-08-25. PMID:34432140. |
muscular hypotonia is a feature of down syndrome (ds), and it affects the tongue and lips. |
2021-08-25 |
2023-08-13 |
Not clear |
| Kristin M Jensen, Elizabeth J Campagna, Elizabeth Juarez-Colunga, Desmond K Runyan, Allan V Prochazk. Predictors of Receipt of Clinical Preventive Services in Adolescents and Adults with Down Syndrome Accessing Medicaid. Disability and health journal. vol 14. issue 2. 2021-08-24. PMID:33229308. |
persons with down syndrome (ds) require preventive care that addresses their age-/gender- and syndrome-specific needs. |
2021-08-24 |
2023-08-13 |
Not clear |
| Ye Hyung Lee, Eunju Im, Minju Hyun, Joongkyu Park, Kwang Chul Chun. Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation. The Journal of biological chemistry. vol 296. 2021-08-24. PMID:33380426. |
down syndrome (ds) is mainly caused by an extra copy of chromosome 21 (trisomy 21), and patients display a variety of developmental symptoms, including characteristic facial features, physical growth delay, intellectual disability, and neurodegeneration (i.e., alzheimer's disease; ad). |
2021-08-24 |
2023-08-13 |
human |
| Jared R Thomas, Randall J Rope. Current Analysis of Skeletal Phenotypes in Down Syndrome. Current osteoporosis reports. vol 19. issue 3. 2021-08-24. PMID:33830429. |
down syndrome (ds) is caused by trisomy 21 (ts21) and results in skeletal deficits including shortened stature, low bone mineral density, and a predisposition to early onset osteoporosis. |
2021-08-24 |
2023-08-13 |
Not clear |
| Salena Babb, Sojung Jung, Ciara Ousley, David McNaughton, Janice Ligh. Personalized AAC Intervention to Increase Participation and Communication for a Young Adult with Down Syndrome. Topics in language disorders. vol 41. issue 3. 2021-08-24. PMID:34421169. |
many adults with down syndrome (ds) experience difficulty with speech production, and intelligibility challenges and communication breakdowns are common. |
2021-08-24 |
2023-08-13 |
human |
| Emily Worley, Weijie Li, Jordan T Jone. Atypical Presentation of Systemic Arthritis in a Toddler with Down Syndrome. Case reports in pediatrics. vol 2021. 2021-08-24. PMID:34422425. |
children with down syndrome (ds) have complex medical challenges related to abnormalities in their immune system, which can cause a broad spectrum of disease manifestations, which can occur atypically. |
2021-08-24 |
2023-08-13 |
Not clear |
| Dean Huggard, Lynne Kelly, Emer Ryan, Fiona McGrane, Niamh Lagan, Edna Roche, Joanne Balfe, T Ronan Leahy, Orla Franklin, Derek G Doherty, Eleanor J Mollo. Increased systemic inflammation in children with Down syndrome. Cytokine. vol 127. 2021-08-23. PMID:31785499. |
children with down syndrome (ds) develop more infections, have an increased mortality from sepsis and an increased incidence of chronic inflammatory conditions. |
2021-08-23 |
2023-08-13 |
Not clear |
| Karl Wehbe, Pauline Brun, Marion Gornet, Jean-Paul Bory, Émilie Raimond, Olivier Graesslin, Coralie Barbe, Laura Dumini. DEPIST 21: Information and knowledge of pregnant women about screening strategies including non-invasive prenatal testing for Down syndrome. Journal of gynecology obstetrics and human reproduction. vol 50. issue 7. 2021-08-23. PMID:33246134. |
to evaluate the knowledge of pregnant women and provide information about down syndrome (ds) screening, including non-invasive prenatal testing (nipt). |
2021-08-23 |
2023-08-13 |
Not clear |
| Beatriz Elizabeth Bagatin Veleda Bermudez, Maria Eduarda de Souza do Amaral, Charles da Silva Gomes, Iolanda Maria Novadzki, Camila Maciel de Oliveir. Respiratory and otolaryngological disorders in Down syndrome from one center in Brazil. American journal of medical genetics. Part A. vol 185. issue 8. 2021-08-23. PMID:34047053. |
down syndrome (ds) is the most common chromosomal condition. |
2021-08-23 |
2023-08-13 |
Not clear |
| Jose L Martinez, Matthew D Zammit, Nicole R West, Bradley T Christian, Anita Bhattacharyy. Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer's Disease. Frontiers in aging neuroscience. vol 13. 2021-08-23. PMID:34322015. |
down syndrome (ds, trisomy 21) is characterized by intellectual impairment at birth and alzheimer's disease (ad) pathology in middle age. |
2021-08-23 |
2023-08-13 |
human |
| Prachi A Patkee, Ana A Baburamani, Katherine R Long, Ralica Dimitrova, Judit Ciarrusta, Joanna Allsop, Emer Hughes, Johanna Kangas, Grainne M McAlonan, Mary A Rutherford, Enrico De Vit. Neurometabolite mapping highlights elevated myo-inositol profiles within the developing brain in down syndrome. Neurobiology of disease. vol 153. 2021-08-20. PMID:33711492. |
the neurodevelopmental phenotype in down syndrome (ds), or trisomy 21, is variable including a wide spectrum of cognitive impairment and a high risk of early-onset alzheimer's disease (ad). |
2021-08-20 |
2023-08-13 |
human |
| Narges Vali Noghondar, Mehdi Sohrabi, Hamid Reza Taheri, Hamid Reza Kobravi, Ezzat Khodashena. The effect of training on variability and accuracy of overhand throwing in children with Down syndrome. International journal of developmental disabilities. vol 67. issue 4. 2021-08-20. PMID:34408858. |
people with down syndrome (ds) have higher variability in their motor skills compared to other counterparts without intellectual disability. |
2021-08-20 |
2023-08-13 |
Not clear |
| Sidra Kaleem Jafri, Karen Elizabeth Harma. Neurocognitive abilities in individuals with Down syndrome-a narrative review. The Turkish journal of pediatrics. vol 62. issue 6. 2021-08-19. PMID:33372428. |
down syndrome (ds), or trisomy 21, is the most common genetic syndrome associated with intellectual disability. |
2021-08-19 |
2023-08-13 |
Not clear |
| Rebekah Johnson, Julia Looper, Alyssa Fis. Current Trends in Pediatric Physical Therapy Practice for Children With Down Syndrome. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 33. issue 2. 2021-08-19. PMID:33653984. |
physical therapists (pts) have a broad range of approaches to the management of down syndrome (ds). |
2021-08-19 |
2023-08-13 |
Not clear |
| Federico Quinzi, Valentina Camomilla, Cecilia Bratta, Maria Francesca Piacentini, Paola Sbriccoli, Giuseppe Vannozz. Hopping skill in individuals with Down syndrome: A qualitative and quantitative assessment. Human movement science. vol 78. 2021-08-19. PMID:34022547. |
individuals with down syndrome (ds) show a delayed acquisition of gross motor skills. |
2021-08-19 |
2023-08-13 |
Not clear |