| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Colin C Anderson, John O Marentette, Kendra M Prutton, Abhishek K Rauniyar, Julie A Reisz, Angelo D'Alessandro, Kenneth N Maclean, Laura M Saba, James R Roed. Trisomy 21 results in modest impacts on mitochondrial function and central carbon metabolism. Free radical biology & medicine. vol 172. 2021-08-19. PMID:34129926. |
down syndrome (ds) is the most common genetic cause of intellectual disability. |
2021-08-19 |
2023-08-13 |
Not clear |
| Falin He, Bo Lin, Kai Mou, Lizi Jin, Juntao Li. A machine learning model for the prediction of down syndrome in second trimester antenatal screening. Clinica chimica acta; international journal of clinical chemistry. vol 521. 2021-08-19. PMID:34274342. |
down syndrome (ds) is the most common human chromosomal abnormality. |
2021-08-19 |
2023-08-13 |
human |
| Mandula Phani Priya, Neerja Gupta, Aditya Nagori, Rakesh Lodha, Vandana Jain, R M Pandey, Madhulika Kabr. Physical Growth and Its Determinants in Indian Children with Down Syndrome, from 3 Months to 5 Years of Age. Indian journal of pediatrics. 2021-08-19. PMID:34410620. |
to compare the growth of indian children with down syndrome (ds), with typically developing indian children. |
2021-08-19 |
2023-08-13 |
Not clear |
| Laura Xicota, Joan Rodríguez, Klaus Langohr, Montserrat Fitó, Mara Dierssen, Rafael de la Torr. Effect of epigallocatechin gallate on the body composition and lipid profile of down syndrome individuals: Implications for clinical management. Clinical nutrition (Edinburgh, Scotland). vol 39. issue 4. 2021-08-18. PMID:31229326. |
individuals with down syndrome (ds) have higher rates of obesity. |
2021-08-18 |
2023-08-13 |
Not clear |
| Eric D Hamlett, Erik Hjorth, Aurélie Ledreux, Anah Gilmore, Marianne Schultzberg, Ann Charlotte Granhol. RvE1 treatment prevents memory loss and neuroinflammation in the Ts65Dn mouse model of Down syndrome. Glia. vol 68. issue 7. 2021-08-18. PMID:31944407. |
individuals with down syndrome (ds) exhibit accelerated acquisition of ad neuropathology, dementia, and neuroinflammation at an earlier age than the general population. |
2021-08-18 |
2023-08-13 |
mouse |
| Anne E Roll, Laura M Koehl. One social network, two perspectives: Social networks of people with Down syndrome based on self-reports and proxy reports. Journal of applied research in intellectual disabilities : JARID. vol 33. issue 6. 2021-08-18. PMID:32285593. |
this study shows that a multi-informant approach to collecting social network data improves our understanding of the social worlds of people with down syndrome (ds). |
2021-08-18 |
2023-08-13 |
Not clear |
| Jo Van Herwegen, Erica Ranzato, Annette Karmiloff-Smith, Victoria Simm. The foundations of mathematical development in Williams syndrome and Down syndrome. Journal of applied research in intellectual disabilities : JARID. vol 33. issue 5. 2021-08-18. PMID:32307875. |
studies in down syndrome (ds) and williams syndrome (ws) have suggested that mathematical abilities are impaired. |
2021-08-18 |
2023-08-13 |
Not clear |
| Michael S Rafi. Alzheimer's Disease in Down Syndrome: Progress in the Design and Conduct of Drug Prevention Trials. CNS drugs. vol 34. issue 8. 2021-08-18. PMID:32506291. |
individuals with down syndrome (ds) are at high risk for developing alzheimer's disease (ad) pathology and this has provided significant insights into our understanding of the genetic basis of ad. |
2021-08-18 |
2023-08-13 |
Not clear |
| Talia Thompson, Devadrita Talapatra, Cynthia E Hazel, Jeanine Coleman, Nicholas Cutfort. Thriving with Down syndrome: A qualitative multiple case study. Journal of applied research in intellectual disabilities : JARID. vol 33. issue 6. 2021-08-18. PMID:32538538. |
down syndrome (ds) is the most common genetic cause of intellectual disability. |
2021-08-18 |
2023-08-13 |
Not clear |
| Nicolas M Oreskovic, Clorinda Cottrell, Amy Torres, Vasiliki Patsiogiannis, Stephanie Santoro, Dominica Nichols, Cynthia Moore, Brian G Skotk. Physical activity patterns in adults with Down Syndrome. Journal of applied research in intellectual disabilities : JARID. vol 33. issue 6. 2021-08-18. PMID:32662165. |
individuals with down syndrome (ds) are less physically active than the general population, but limited data on objective physical activity patterns in adults with ds are available. |
2021-08-18 |
2023-08-13 |
Not clear |
| Tomohiko Nishino, Shota Endo, Hiroki Miyano, Chisato Umeda, Yuji Tomii, Yoshitaka Watanabe, Mayu Nakagawa, Daisuke Kakegawa, Shuichiro Fujinag. Is the estimated glomerular filtration rate formula useful for evaluating the renal function of Down syndrome? Pediatrics international : official journal of the Japan Pediatric Society. vol 63. issue 8. 2021-08-18. PMID:33202080. |
children with down syndrome (ds) have different growth rates compared with normal children. |
2021-08-18 |
2023-08-13 |
Not clear |
| Veronica Fitzpatrick, Anne Rivelli, Kelsey Bria, Brian Chicoin. Heart Disease in Adults With Down Syndrome Between 1996 and 2016. Journal of the American Board of Family Medicine : JABFM. vol 33. issue 6. 2021-08-18. PMID:33219071. |
to describe demographic factors and calculate prevalence of heart disease-related conditions among the adult down syndrome (ds) sample population and to compare demographic and heart disease-related conditions between the ds sample population (n = 2342) and the general population. |
2021-08-18 |
2023-08-13 |
Not clear |
| Wayne Silverman, Sharon J Krinsky-McHale, Florence Lai, H Diana Rosas, Christy Hom, Eric Doran, Margaret Pulsifer, Ira Lott, Nicole Schup. Evaluation of the National Task Group-Early Detection Screen for Dementia: Sensitivity to 'mild cognitive impairment' in adults with Down syndrome. Journal of applied research in intellectual disabilities : JARID. vol 34. issue 3. 2021-08-18. PMID:33314467. |
the accuracy of the national task group-early detection screen for dementia (ntg-edsd) was evaluated in a sample of 185 adults with down syndrome (ds), emphasizing 'mild cognitive impairment (mci-ds)'. |
2021-08-18 |
2023-08-13 |
Not clear |
| Mahmoud Omar, Jennifer L McCoy, Andrew A McCormick, Kishore Vellody, David H Ch. Repeat tympanostomy tubes in children with Down syndrome. International journal of pediatric otorhinolaryngology. vol 148. 2021-08-18. PMID:34198227. |
children with down syndrome (ds) have a higher incidence of tympanostomy tube insertion (tti) than children in the general population. |
2021-08-18 |
2023-08-13 |
Not clear |
| Dean Huggard, Lynne Kelly, Amy Worrall, Eleanor Gallagher, Lida Fallah, Lucas Lu Yoo, Fiona McGrane, Niamh Lagan, Edna Roche, Joanne Balfe, Derek G Doherty, Eleanor J Mollo. Melatonin as an immunomodulator in children with Down syndrome. Pediatric research. 2021-08-17. PMID:34400791. |
down syndrome (ds) is a disorder characterised by marked immune dysfunction, increased mortality from sepsis, chronic inflammation, increased oxidative stress, sleep disturbance and possibly abnormal endogenous melatonin levels. |
2021-08-17 |
2023-08-13 |
Not clear |
| Bassil Mashaqba, Haneen Abu Sa'aleek, Anas Huneety, Sabri Al-Shbou. Grammatical number inflection in Arabic-speaking children and young adults with Down syndrome. The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings. vol 67. issue 1. 2021-08-13. PMID:33179943. |
individuals with down syndrome (ds) have more difficulties with the structural aspects of language, including morphology (concatenation and non-concatenation) and syntax (word order and grammatical/concord rules), than with other language components (e.g. |
2021-08-13 |
2023-08-13 |
Not clear |
| Alberto Lleó, Maria Carmona-Iragui, Laura Videla, Susana Fernández, Bessy Benejam, Jordi Pegueroles, Isabel Barroeta, Miren Altuna, Silvia Valldeneu, Mei-Fang Xiao, Desheng Xu, Raúl Núñez-Llaves, Marta Querol-Vilaseca, Sònia Sirisi, Alexandre Bejanin, M Florencia Iulita, Jordi Clarimón, Rafael Blesa, Paul Worley, Daniel Alcolea, Juan Fortea, Olivia Belbi. VAMP-2 is a surrogate cerebrospinal fluid marker of Alzheimer-related cognitive impairment in adults with Down syndrome. Alzheimer's research & therapy. vol 13. issue 1. 2021-08-13. PMID:34183050. |
there is an urgent need for objective markers of alzheimer's disease (ad)-related cognitive impairment in people with down syndrome (ds) to improve diagnosis, monitor disease progression, and assess response to disease-modifying therapies. |
2021-08-13 |
2023-08-13 |
human |
| Alexandre Bejanin, Maria Florencia Iulita, Eduard Vilaplana, Maria Carmona-Iragui, Bessy Benejam, Laura Videla, Isabel Barroeta, Susana Fernandez, Miren Altuna, Jordi Pegueroles, Victor Montal, Silvia Valldeneu, Sandra Giménez, Sofía González-Ortiz, Laia Muñoz, Concepción Padilla, Mateus Rozalem Aranha, Teresa Estellés, Ignacio Illán-Gala, Olivia Belbin, Valle Camacho, Liam Reese Wilson, Tiina Annus, Ricardo S Osorio, Sebastián Videla, Sylvain Lehmann, Anthony J Holland, Henrik Zetterberg, Kaj Blennow, Daniel Alcolea, Jordi Clarimon, Shahid H Zaman, Rafael Blesa, Alberto Lleó, Juan Forte. Association of Apolipoprotein E ɛ4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome. JAMA neurology. vol 78. issue 8. 2021-08-13. PMID:34228042. |
alzheimer disease (ad) is the leading cause of death in individuals with down syndrome (ds). |
2021-08-13 |
2023-08-13 |
Not clear |
| Jesús David Urbano-Gámez, Juan José Casañas, Itziar Benito, María Luz Montesino. Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down's syndrome mouse model. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34034796. |
down syndrome (ds) is the most frequent genetic cause of intellectual disability including hippocampal-dependent memory deficits. |
2021-08-12 |
2023-08-13 |
mouse |
| Y Zhang, Z Tian, S Ye, Q Mu, X Wang, S Ren, X Hou, W Yu, J Gu. Changes in bone mineral density in Down syndrome individuals: a systematic review and meta-analysis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2021-08-12. PMID:34383099. |
data evaluating changes in bone mineral density (bmd) in down syndrome (ds) individuals remains controversial. |
2021-08-12 |
2023-08-13 |
Not clear |