| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth B Malinza. Perioperative care of adults with Down syndrome: a narrative review. Canadian journal of anaesthesia = Journal canadien d'anesthesie. vol 68. issue 10. 2021-09-13. PMID:34165727. |
because of enhanced life expectancy due to medical and surgical therapeutic advances, it is estimated that there are more adults than children living with down syndrome (ds), or trisomy 21, in the united states. |
2021-09-13 |
2023-08-13 |
Not clear |
| b' Ivan Ali\\xc4\\x87, Pollyanna A Goh, Aoife Murray, Erik Portelius, Eleni Gkanatsiou, Gillian Gough, Kin Y Mok, David Koschut, Reinhard Brunmeir, Yee Jie Yeap, Niamh L O\'Brien, J\\xc3\\xbcrgen Groet, Xiaowei Shao, Steven Havlicek, N Ray Dunn, Hlin Kvartsberg, Gunnar Brinkmalm, Rosalyn Hithersay, Carla Startin, Sarah Hamburg, Margaret Phillips, Konstantin Pervushin, Mark Turmaine, David Wallon, Anne Rovelet-Lecrux, Hilkka Soininen, Emanuela Volpi, Joanne E Martin, Jia Nee Foo, David L Becker, Agueda Rostagno, Jorge Ghiso, \\xc5\\xbdeljka Krsnik, Goran \\xc5\\xa0imi\\xc4\\x87, Ivica Kostovi\\xc4\\x87, Dinko Mitre\\xc4\\x8di\\xc4\\x87, Paul T Francis, Kaj Blennow, Andre Strydom, John Hardy, Henrik Zetterberg, Dean Ni\\xc5\\xbeeti\\xc4\\x8. Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain. Molecular psychiatry. 2021-09-11. PMID:32647257.' |
a population of more than six million people worldwide at high risk of alzheimer's disease (ad) are those with down syndrome (ds, caused by trisomy 21 (t21)), 70% of whom develop dementia during lifetime, caused by an extra copy of β-amyloid-(aβ)-precursor-protein gene. |
2021-09-11 |
2023-08-13 |
human |
| Massimo Marano, Angelo Pompucci, Francesco Motolese, Mariagrazia Rossi, Ernesto Coletta, Vincenzo Di Lazzaro, Alfonso Fasano, Gianpaolo Petrell. Normal Pressure Hydrocephalus in Down Syndrome: The Report of Two Cases. Journal of Alzheimer's disease : JAD. vol 77. issue 3. 2021-09-09. PMID:32804139. |
down syndrome (ds) is the most common cause of intellectual disability in infants and has a well-known relationship with the alzheimer's disease. |
2021-09-09 |
2023-08-13 |
Not clear |
| Rahul S Bhansali, Malini Rammohan, Paul Lee, Anouchka P Laurent, Qiang Wen, Praveen Suraneni, Bon Ham Yip, Yi-Chien Tsai, Silvia Jenni, Beat Bornhauser, Aurélie Siret, Corinne Fruit, Alexandra Pacheco-Benichou, Ethan Harris, Thierry Besson, Benjamin J Thompson, Young Ah Goo, Nobuko Hijiya, Maria Vilenchik, Shai Izraeli, Jean-Pierre Bourquin, Sébastien Malinge, John D Crispin. DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3. The Journal of clinical investigation. vol 131. issue 1. 2021-09-08. PMID:33393494. |
dyrk1a is a serine/threonine kinase encoded on human chromosome 21 (hsa21) that has been implicated in several pathologies of down syndrome (ds), including cognitive deficits and alzheimer's disease. |
2021-09-08 |
2023-08-13 |
human |
| Alba Puente-Bedia, María T Berciano, Olga Tapia, Carmen Martínez-Cué, Miguel Lafarga, Noemí Rued. Nuclear Reorganization in Hippocampal Granule Cell Neurons from a Mouse Model of Down Syndrome: Changes in Chromatin Configuration, Nucleoli and Cajal Bodies. International journal of molecular sciences. vol 22. issue 3. 2021-09-08. PMID:33514010. |
down syndrome (ds) or trisomy of chromosome 21 (hsa21) is characterized by impaired hippocampal-dependent learning and memory. |
2021-09-08 |
2023-08-13 |
mouse |
| Violetta N Pivtoraiko, Tamara Racic, Eric E Abrahamson, Victor L Villemagne, Benjamin L Handen, Ira T Lott, Elizabeth Head, Milos D Ikonomovi. Postmortem Neocortical Frontiers in aging neuroscience. vol 13. 2021-09-08. PMID:34489686. |
postmortem neocortical individuals with down syndrome (ds) have a genetic predisposition for amyloid-β (aβ) overproduction and earlier onset of aβ deposits compared to patients with sporadic late-onset alzheimer's disease (ad). |
2021-09-08 |
2023-08-13 |
Not clear |
| Nazmus Saquib, Anas Naser Al Sarraj, Baraa Tarek Ziad Oubaied, Ahmad Mamoun Rajab, Bana Nasser Agha, Jesmin Hossain, Abdulrahman Almazrou, Juliann Saqui. Gain in growth after surgical repair of congenital heart disease among children with Down syndrome. American journal of medical genetics. Part A. 2021-09-08. PMID:34496118. |
down syndrome (ds) is a common genetic disorder among saudi children, for which limited data is available on growth for those who undergo surgery for congenital heart disease (chd). |
2021-09-08 |
2023-08-13 |
Not clear |
| Valentina Sas, Cristina Blag, Sergiu Pasca, Gheorghe Popa, Mirela Marian, Cristina Schnell, Daniela Voda, Smaranda Teodora Arghirescu, Patric Teodorescu, Sabina Iluta, Cristina Turcas, Cristina Selicean, Anca Bojan, Mihnea Zdrenghea, Margit Serban, Delia Dima, Gabriela Zaharie, Anca Colita, Sorin Man, Ciprian Tomuleas. Baseline characteristics of a nationwide cohort of pediatric patients with acute leukemias of Down syndrome. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 25. issue 6. 2021-09-07. PMID:33455121. |
down syndrome (ds) or trisomy 21, brings together some unique aspects from clinical pediatrics. |
2021-09-07 |
2023-08-13 |
Not clear |
| Blandine Ponroy Bally, Keith K Mura. Astrocytes in Down Syndrome Across the Lifespan. Frontiers in cellular neuroscience. vol 15. 2021-09-07. PMID:34483840. |
down syndrome (ds) is the most common genetic cause of intellectual disability in which delays and impairments in brain development and function lead to neurological and cognitive phenotypes. |
2021-09-07 |
2023-08-13 |
Not clear |
| Carolyn F Ross, Victoria A Surette, Charles B Bernhard, Sarah Smith-Simpson, Jookyeong Lee, Catherine G Russell, Russell Keas. Development and application of specific questions to classify a child as food texture sensitive. Journal of texture studies. 2021-09-06. PMID:34435671. |
three sets of survey data were examined, including data from a home-use test (hut) in children with and without down syndrome (ds), and lingual tactile sensitivity measured by grating orientation task (got). |
2021-09-06 |
2023-08-13 |
Not clear |
| Brian Chicoine, Anne Rivelli, Veronica Fitzpatrick, Laura Chicoine, Gengjie Jia, Andrey Rzhetsk. Prevalence of Common Disease Conditions in a Large Cohort of Individuals With Down Syndrome in the United States. Journal of patient-centered research and reviews. vol 8. issue 2. 2021-09-04. PMID:33898640. |
given the current life expectancy and number of individuals living with down syndrome (ds), it is important to learn common occurrences of disease conditions across the developmental lifespan. |
2021-09-04 |
2023-08-13 |
Not clear |
| C S Musaeus, L C Salem, T W Kjaer, G Waldema. Electroencephalographic functional connectivity is altered in persons with Down syndrome and Alzheimer's disease. Journal of intellectual disability research : JIDR. vol 65. issue 3. 2021-09-03. PMID:33336867. |
persons with down syndrome (ds) are at increased risk of developing alzheimer's dementia (ds-ad). |
2021-09-03 |
2023-08-13 |
Not clear |
| G G Faught, Z M Himmelberger, A S Tungate, F A Conner. Sustained attention to response task performance trajectories in Down syndrome. Journal of intellectual disability research : JIDR. vol 65. issue 3. 2021-09-03. PMID:33368698. |
sustained attention (sa) has been reported to be a unitary construct in youth with down syndrome (ds), but additional analyses of how auditory and visual sa change over task presentation time are warranted. |
2021-09-03 |
2023-08-13 |
Not clear |
| Erin E Wentz, Julia Looper, Kristi S Menear, Dipika Rohadia, Nora Shield. Promoting Participation in Physical Activity in Children and Adolescents With Down Syndrome. Physical therapy. vol 101. issue 5. 2021-09-03. PMID:33517447. |
children with down syndrome (ds) often have lower physical activity (pa) levels compared with their peers with typical development, and face challenges to being physically active such as medical comorbidities, access issues, and societal stigma. |
2021-09-03 |
2023-08-13 |
Not clear |
| M Rosety-Rodriguez, M Bernardi, S Elosegui, I Rosety, A J Diaz, M A Rosety, F Brenes, A Oliva-Pascual-Vaca, J R Alvero-Cruz, F J Ordone. A Short-Term Resistance Training Circuit Improved Antioxidants in Sedentary Adults with Down Syndrome. Oxidative medicine and cellular longevity. vol 2021. 2021-09-02. PMID:33532037. |
previous studies have found aerobic training improved oxidative damage in people with down syndrome (ds). |
2021-09-02 |
2023-08-13 |
Not clear |
| Maria Dolores Figueroa-Jiménez, Cristina Cañete-Massé, María Carbó-Carreté, Daniel Zarabozo-Hurtado, Joan Guàrdia-Olmo. Structural equation models to estimate dynamic effective connectivity networks in resting fMRI. A comparison between individuals with Down syndrome and controls. Behavioural brain research. vol 405. 2021-09-02. PMID:33636235. |
the aim of the paper was to find the best structural equation model (sem) to represent dynamic effective connectivity in people with down syndrome (ds) in comparison with healthy controls. |
2021-09-02 |
2023-08-13 |
human |
| K Armijos-Yambay, J A Jordán Sierr. Fathers matter too! Lived experience of pedagogical hope in raising children with Down syndrome. Journal of intellectual disability research : JIDR. vol 64. issue 6. 2021-09-01. PMID:31638300. |
this attitude among fathers of children with down syndrome (ds) plays an essential role in their children's development. |
2021-09-01 |
2023-08-13 |
Not clear |
| E Lorang, S Hartley, A Sterlin. Physiological arousal and observed behaviour in parent-child interactions involving young children with Down syndrome. Journal of intellectual disability research : JIDR. vol 64. issue 6. 2021-09-01. PMID:31971300. |
parents of children with down syndrome (ds) play an important role in their child's development. |
2021-09-01 |
2023-08-13 |
Not clear |
| D Orthmann Bless, V Hofman. Abortion in women with Down syndrome. Journal of intellectual disability research : JIDR. vol 64. issue 9. 2021-09-01. PMID:32643815. |
nearly two-thirds of pregnancies in women with down syndrome (ds) end in abortion. |
2021-09-01 |
2023-08-13 |
Not clear |
| E K Schworer, D J Fidler, M Kaur, A W Needham, M A Prince, L A Daunhaue. Goal-directed action planning in infants with Down syndrome. Journal of intellectual disability research : JIDR. vol 64. issue 9. 2021-09-01. PMID:32666591. |
down syndrome (ds) is a neurogenetic disorder associated with risk for executive dysfunction, or difficulties with the cognitive processes required for planning volitional, goal-directed behaviour. |
2021-09-01 |
2023-08-13 |
Not clear |