| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arnaud Duchon, Agnès Gruart, Christelle Albac, Benoît Delatour, Javier Zorrilla de San Martin, José María Delgado-García, Yann Hérault, Marie-Claude Potie. Long-lasting correction of in vivo LTP and cognitive deficits of mice modelling Down syndrome with an α5-selective GABA British journal of pharmacology. vol 177. issue 5. 2021-06-21. PMID:31652355. |
long-lasting correction of in vivo ltp and cognitive deficits of mice modelling down syndrome with an α5-selective gaba excessive gabaergic inhibition contributes to cognitive dysfunctions in down syndrome (ds). |
2021-06-21 |
2023-08-13 |
mouse |
| Astrid C Hengartner, Ros Whelan, Roberta Maj, Kristine Wolter-Warmerdam, Francis Hickey, Todd C Hankinso. Evaluation of 2011 AAP cervical spine screening guidelines for children with Down Syndrome. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. vol 36. issue 11. 2021-06-21. PMID:32778937. |
atlantoaxial instability (aai) has a higher incidence rate among individuals with down syndrome (ds) than the non-ds population. |
2021-06-21 |
2023-08-13 |
Not clear |
| Jens Schuster, Jan Hoeber, Maria Sobol, Ambrin Fatima, Göran Annerén, Niklas Dah. Generation of two human iPSC lines (UUIGPi013-A and UUIPGi014-A) from cases with Down syndrome and full trisomy for chromosome 21 (T21). Stem cell research. vol 49. 2021-06-21. PMID:33220594. |
down syndrome (ds) is caused by trisomy for chromosome 21 (t21). |
2021-06-21 |
2023-08-13 |
human |
| Jasneek K Chawla, Aidan Howard, Scott Burgess, Helen Heussle. Sleep problems in Australian children with Down syndrome: the need for greater awareness. Sleep medicine. vol 78. 2021-06-21. PMID:33412456. |
children with down syndrome (ds) have a high prevalence of obstructive sleep apnoea (osa). |
2021-06-21 |
2023-08-13 |
Not clear |
| Fabiana de C Gomes, Marlon F Mattos, Eny M Goloni-Bertollo, Érika C Pavarin. Alzheimer's Disease in the Down Syndrome: An Overview of Genetics and Molecular Aspects. Neurology India. vol 69. issue 1. 2021-06-21. PMID:33642267. |
the overexpression of the amyloid precursor protein (app) gene, encoded on chromosome 21, has been associated in down syndrome (ds) with the development of early-onset alzheimer's disease (eoad). |
2021-06-21 |
2023-08-13 |
Not clear |
| Raymond D Kent, Julie Eichhorn, Erin M Wilson, Youmi Suk, Daniel M Bolt, Houri K Vorperia. Auditory-Perceptual Features of Speech in Children and Adults With Down Syndrome: A Speech Profile Analysis. Journal of speech, language, and hearing research : JSLHR. vol 64. issue 4. 2021-06-21. PMID:33789057. |
purpose the aim of this study was to determine how the speech disorder profiles in down syndrome (ds) relate to reduced intelligibility, atypical overall quality, and impairments in the subsystems of speech production (phonation, articulation, resonance, and prosody). |
2021-06-21 |
2023-08-13 |
Not clear |
| Manisha Gadgeel, Batool AlQanber, Steven Buck, Jeffrey W Taub, Yaddanapudi Ravindranath, Süreyya Savaşa. Aberrant myelomonocytic CD56 expression in Down syndrome is frequent and not associated with leukemogenesis. Annals of hematology. vol 100. issue 7. 2021-06-21. PMID:33890142. |
children with down syndrome (ds) are at an increased risk of developing transient abnormal myelopoiesis (tam) and acute leukemia. |
2021-06-21 |
2023-08-13 |
Not clear |
| Elisa Fucà, Floriana Costanzo, Laura Celestini, Alessandra Mandarino, Stefano Vicar. Characterization of Sleep Disturbances in Children and Adolescents with Down Syndrome and Their Relation with Cognitive and Behavioral Features. International journal of environmental research and public health. vol 18. issue 9. 2021-06-21. PMID:34065045. |
despite sleep disturbances are common among youths with down syndrome (ds), the cognitive and behavioral features associated with sleep problems have not yet been studied extensively. |
2021-06-21 |
2023-08-13 |
Not clear |
| Falin He, Wei Wang, Kun Zhong, Shuai Yuan, Yuxuan Du, Zhiguo Wan. Analysis of External Quality Assessment of Maternal Serum Prenatal Screening for Down Syndrome in the First Trimester in China. Clinical laboratory. vol 67. issue 6. 2021-06-21. PMID:34107630. |
we analyzed the 2019 external quality assessment (eqa) results to evaluate the analytical performance of maternal serum prenatal screening for down syndrome (ds) in the first trimester in china. |
2021-06-21 |
2023-08-13 |
Not clear |
| Matthew Beerse, Diego Ferreira, Jianhua W. Muscle activation pattern during two-legged hopping in children with and without Down syndrome. Journal of motor behavior. 2021-06-21. PMID:34148524. |
this study aimed to characterize muscle activation and its variability during two-legged hopping in children with and without down syndrome (ds). |
2021-06-21 |
2023-08-13 |
human |
| Sharon J Krinsky-McHale, Warren B Zigman, Joseph H Lee, Nicole Schupf, Deborah Pang, Tracy Listwan, Cynthia Kovacs, Wayne Silverma. Promising outcome measures of early Alzheimer's dementia in adults with Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-06-19. PMID:32647741. |
adults with down syndrome (ds) are at high risk for developing alzheimer's disease (ad) and its associated dementia, warranting the development of strategies to improve early detection when prevention is possible. |
2021-06-19 |
2023-08-13 |
Not clear |
| Yan-Jiao Lu, Wen-Wen Yu, Meng-Meng Cui, Xian-Xian Yu, Huan-Lei Song, Mei-Rong Bai, Wen-Jie Wu, Bei-Lin Gu, Jun Wang, Wei Cai, Xun Ch. Association Analysis of Variants of Frontiers in cell and developmental biology. vol 9. 2021-06-19. PMID:34136475. |
association analysis of variants of hirschsprung disease (hscr) has a higher incidence in children with down syndrome (ds), which makes trisomy 21 a predisposing factor to hscr. |
2021-06-19 |
2023-08-13 |
Not clear |
| Jonathan M LaCombe, Randall J Rope. Skeletal dynamics of Down syndrome: A developing perspective. Bone. vol 133. 2021-06-17. PMID:31887437. |
individuals with down syndrome (ds) display distinctive skeletal morphology compared to the general population, but disparate descriptions, methodologies, analyses, and populations sampled have led to diverging conclusions about this unique skeletal phenotype. |
2021-06-17 |
2023-08-13 |
mouse |
| Jared R Thomas, Jonathan LaCombe, Rachel Long, Eva Lana-Elola, Sheona Watson-Scales, Joseph M Wallace, Elizabeth M C Fisher, Victor L J Tybulewicz, Randall J Rope. Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome. Bone. vol 136. 2021-06-17. PMID:32305495. |
all individuals with down syndrome (ds), which results from trisomy of human chromosome 21 (ts21), present with skeletal abnormalities typified by craniofacial features, short stature and low bone mineral density (bmd). |
2021-06-17 |
2023-08-13 |
mouse |
| Anke Hüls, Alberto C S Costa, Mara Dierssen, R Asaad Baksh, Stefania Bargagna, Nicole T Baumer, Ana Claudia Brandão, Angelo Carfi, Maria Carmona-Iragui, Brain Allen Chicoine, Sujay Ghosh, Monica Lakhanpaul, Coral Manso, Miguel-Angel Mayer, Maria Del Carmen Ortega, Diego Real de Asua, Anne-Sophie Rebillat, Lauren Ashley Russell, Giuseppina Sgandurra, Diletta Valentini, Stephanie L Sherman, Andre Strydo. An international survey on the impact of COVID-19 in individuals with Down syndrome. medRxiv : the preprint server for health sciences. 2021-06-17. PMID:33173907. |
health conditions and immune dysfunction associated with trisomy 21 (down syndrome, ds) may impact the clinical course of covid-19 once infected by sars-cov-2. |
2021-06-17 |
2023-08-13 |
Not clear |
| Monica Shah, Muskaan Sachdeva, Maria Melendez-Gonzalez, Vincent Piguet, Christopher Saye. Hidradenitis suppurativa and chromosomal abnormalities: a case report and systematic review of the literature. International journal of dermatology. vol 60. issue 3. 2021-06-17. PMID:33599294. |
of the 13 articles, nine studies reported patients with hs and down syndrome (ds), one article investigated hs and smith-magenis syndrome (sms), and three articles analyzed hs and patau syndrome (ps). |
2021-06-17 |
2023-08-13 |
human |
| Keiichi Ishihar. [Is Neuron-Vascular Communication Disturbed in the Delayed Prenatal Brain Development of a Mouse Model of Down Syndrome?] Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 141. issue 3. 2021-06-16. PMID:33642505. |
developmental retardation of the brain with reduced cortical neurogenesis is observed in ts1cje mice, a model of down syndrome (ds) as it is in people with ds; however, the mechanisms and the responsible gene(s) remain unknown. |
2021-06-16 |
2023-08-13 |
mouse |
| Xiaohang Chen, Liang Hu, Jinjiang Su, Xiaoyi Liu, Xiaojin Luo, Yuanyuan Pei, Yushan Gao, Fengxiang We. Amniotic fluid and urine metabolomic alterations associated with pregnant women with Down syndrome fetuses. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2021-06-16. PMID:34130603. |
down syndrome (ds) is a chromosomal disorder caused by a third copy of all or part of chromosome 21. |
2021-06-16 |
2023-08-13 |
Not clear |
| Caroline M Kolb, Udayan Shah, Nicole L Aaronso. Interstate variation within a five-state health system: Polysomnography prior to tonsillectomy in trisomy 21 patients. International journal of pediatric otorhinolaryngology. vol 138. 2021-06-15. PMID:32891943. |
since 2011, the american academy of otolaryngology - head and neck surgery clinical practice guidelines have recommended polysomnography (psg) prior to tonsillectomy in children with down syndrome (ds). |
2021-06-15 |
2023-08-13 |
Not clear |
| Manju S Hurvitz, Daniel J Lesser, Gretchen Dever, Janelle Celso, Rakesh Bhattacharje. Findings of routine nocturnal polysomnography in children with Down syndrome: a retrospective cohort study. Sleep medicine. vol 76. 2021-06-15. PMID:33120129. |
children with down syndrome (ds) are at risk for sleep disorders including; obstructive sleep apnea (osa). |
2021-06-15 |
2023-08-13 |
Not clear |