| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deirdre O' Leary, Alice Lee, Ciara O'Toole, Fiona Gibbo. Perceptual and acoustic evaluation of speech production in Down syndrome: A case series. Clinical linguistics & phonetics. vol 34. issue 1-2. 2021-06-28. PMID:31345071. |
people with down syndrome (ds) can experience difficulties with speech production that can impact on speech intelligibility. |
2021-06-28 |
2023-08-13 |
human |
| Taralee Hamner, Susan Hepburn, Fengqing Zhang, Deborah Fidler, Cordelia Robinson Rosenberg, Diana L Robins, Nancy R Le. Cognitive Profiles and Autism Symptoms in Comorbid Down Syndrome and Autism Spectrum Disorder. Journal of developmental and behavioral pediatrics : JDBP. vol 41. issue 3. 2021-06-28. PMID:31599791. |
the prevalence of comorbid autism spectrum disorder (asd) in children with down syndrome (ds) is estimated to be around 16%. |
2021-06-28 |
2023-08-13 |
Not clear |
| Chiara Lanzillotta, Antonella Tramutola, Graziella Di Giacomo, Federico Marini, D Allan Butterfield, Fabio Di Domenico, Marzia Perluigi, Eugenio Baron. Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome. Free radical biology & medicine. vol 165. 2021-06-28. PMID:33516914. |
since down syndrome (ds) and ad neuropathology share many common features, we investigated metabolic aspects of neurodegeneration in ds and whether they contribute to early onset ad in ds. |
2021-06-28 |
2023-08-13 |
mouse |
| Jiao-Jiao Xi, Guan-Heng Yang, Yan-Na Liu, Jia-Jun Qiu, Xiu-Li Gong, Jing-Bin Yan, Fanyi Zen. Genome-wide hypermethylation is closely associated with abnormal expression of genes involved in neural development in induced pluripotent stem cells derived from a Down syndrome mouse model. Cell biology international. vol 45. issue 7. 2021-06-28. PMID:33527608. |
mental retardation is the main clinical manifestation of down syndrome (ds), and neural abnormalities occur during the early embryonic period and continue throughout life. |
2021-06-28 |
2023-08-13 |
mouse |
| Erica Ranzato, Andrew Tolmie, Jo Van Herwege. The Home Learning Environment of Primary School Children with Down Syndrome and those with Williams Syndrome. Brain sciences. vol 11. issue 6. 2021-06-27. PMID:34073060. |
research on typically developing (td) populations has shown that the home learning environment plays a significant role in cognitive development and learning, but very little is known about the home learning environment of children with down syndrome (ds) or children with williams syndrome (ws). |
2021-06-27 |
2023-08-13 |
Not clear |
| Barbara Cisterna, Anatoly P Sobolev, Manuela Costanzo, Manuela Malatesta, Carlo Zancanar. Combined Microscopic and Metabolomic Approach to Characterize the Skeletal Muscle Fiber of the Ts65Dn Mouse, A Model of Down Syndrome. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. vol 26. issue 5. 2021-06-25. PMID:32867866. |
down syndrome (ds) is a genetically based disease caused by triplication of chromosome 21. |
2021-06-25 |
2023-08-13 |
mouse |
| Ana Wintergerst, Marcela Patricia López-Morale. Masticatory function in children with Down syndrome. Physiology & behavior. vol 235. 2021-06-25. PMID:33736969. |
the objective was to study masticatory function of 8 to 10-year-old children with down syndrome (ds) through the evaluation of maximum occlusal force and masticatory performance (via medium particle size) and compare it to that of children of the same age without ds. |
2021-06-25 |
2023-08-13 |
Not clear |
| Iulia Ioan, Diane Whitney, François Sevin, Damien Sanlaville, Bénédicte De Fréminville, Cyril Schweitzer, Mohamed Akkari, Laurianne Coutier, Benjamin Putois, Marine Thieux, Patricia Franc. Pulse transit time as a diagnostic test for OSA in children with Down syndrome. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2021-06-25. PMID:34170228. |
children with down syndrome (ds) are at risk of obstructive sleep apnea (osa), but the access to sleep lab polysomnography (psg) is limited. |
2021-06-25 |
2023-08-13 |
Not clear |
| Marie Moore Channel. Cross-Sectional Trajectories of Mental State Language Development in Children With Down Syndrome. American journal of speech-language pathology. vol 29. issue 2. 2021-06-24. PMID:32293911. |
purpose this article (a) examined the cross-sectional trajectories of mental state language use in children with down syndrome (ds) and (b) identified developmental factors associated with its use. |
2021-06-24 |
2023-08-13 |
Not clear |
| Andrea Barton-Hulsey, Emily Lorang, Kallie Renfus, Audra Sterlin. Maternal Input and Child Language Comprehension During Book Reading in Children With Down Syndrome. American journal of speech-language pathology. vol 29. issue 3. 2021-06-24. PMID:32463706. |
this study examined maternal language input and child expressive communication during a shared book reading activity in children with down syndrome (ds) and children with typical development (td). |
2021-06-24 |
2023-08-13 |
human |
| Catherine Diskin, Terri P McVeigh, Des W Co. Sleep disordered breathing in children with Down syndrome in the Republic of Ireland. American journal of medical genetics. Part A. vol 182. issue 12. 2021-06-24. PMID:32902194. |
down syndrome (ds) is associated with a complex respiratory phenotype, including obstructive sleep apnea syndrome (osas). |
2021-06-24 |
2023-08-13 |
Not clear |
| Pedro Landete, Joan B Soriano, Beatriz Aldave, Enrique Zamora, Carmen Acosta, Marta Erro, Cristina López Riolobos, M Inmaculata Ramos, Fernando Moldenhauer, Julio Ancoche. Obstructive sleep apnea in adults with Down syndrome. American journal of medical genetics. Part A. vol 182. issue 12. 2021-06-24. PMID:32909685. |
patients with down syndrome (ds) often have a high occurrence of obstructive sleep apnea-hypopnea (osa) syndrome. |
2021-06-24 |
2023-08-13 |
Not clear |
| Catherine Stephan, Liv Clasen, Elizabeth Adeyemi, Nancy Raitano Le. Speech Impairments Explain Unique Variance in Adaptive Behavior Skills in Young People With Down Syndrome. American journal of speech-language pathology. vol 30. issue 1. 2021-06-24. PMID:33197320. |
background down syndrome (ds) is a disorder characterized by impairments in global cognitive abilities and adaptive function. |
2021-06-24 |
2023-08-13 |
Not clear |
| Theresa M Versaci, Laura J Mattie, Laura J Immin. Down Syndrome and Autism Spectrum Disorder Dual Diagnosis: Important Considerations for Speech-Language Pathologists. American journal of speech-language pathology. vol 30. issue 1. 2021-06-24. PMID:33316160. |
purpose individuals with down syndrome (ds) often receive speech-language therapy services starting in infancy or toddlerhood. |
2021-06-24 |
2023-08-13 |
Not clear |
| Xu-Qiao Chen, Utpal Das, Gooho Park, William C Moble. Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport. Alzheimer's research & therapy. vol 13. issue 1. 2021-06-24. PMID:33691783. |
impaired axonal transport may contribute to the pathogenesis of neurodegenerative diseases, including alzheimer's disease (ad) and down syndrome (ds). |
2021-06-24 |
2023-08-13 |
Not clear |
| Dennis Rosen, Laura Berbert, Edie Welle. High prevalence of periodic limb movements of sleep in children with Down syndrome. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 16. issue 3. 2021-06-23. PMID:31992397. |
this study sought to determine the prevalence of elevated plms in a large cohort of children with down syndrome (ds) and their correlation with osa and ferritin levels. |
2021-06-23 |
2023-08-13 |
Not clear |
| Wenwen Yu, Kathleen M Sarber, Javier J M Howard, Guixia Huang, Md Monir Hossain, Christine H Heubi, Xiaofeng Lu, Narong Simakajornboo. Children with Down syndrome and mild OSA: treatment with medication versus observation. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 16. issue 6. 2021-06-23. PMID:32043964. |
children with down syndrome (ds) have a high prevalence of obstructive sleep apnea (osa). |
2021-06-23 |
2023-08-13 |
Not clear |
| Sara Salloum, Yasmina Mahsoun, Talal Al-Khatib, HaniZ Marzouki, Faisal Zawaw. Supraglottoplasty in the management of laryngomalacia in children with down syndrome: A systematic review. International journal of pediatric otorhinolaryngology. vol 142. 2021-06-23. PMID:33477012. |
children with down syndrome (ds) who have laryngomalacia represent a specific management challenge due to their inherent multiple levels of airway obstruction and hypotonia. |
2021-06-23 |
2023-08-13 |
Not clear |
| Sergio Valbuena, Juan Lerm. Losing balance: Kainate receptors and psychiatric disorders comorbidities. Neuropharmacology. vol 191. 2021-06-23. PMID:33862031. |
here, we review the data supporting the involvement of mutations in genes coding for kainate receptor (kar) subunits in the pathogenesis of psychiatric disorders and down syndrome (ds). |
2021-06-23 |
2023-08-13 |
mouse |
| David Mengel, Wen Liu, Robert J Glynn, Dennis J Selkoe, Andre Strydom, Florence Lai, H Diana Rosas, Amy Torres, Vasiliki Patsiogiannis, Brian Skotko, Dominic M Wals. Dynamics of plasma biomarkers in Down syndrome: the relative levels of Aβ42 decrease with age, whereas NT1 tau and NfL increase. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-22. PMID:32192521. |
down syndrome (ds) is the most common genetic cause of alzheimer's disease (ad), but diagnosis of ad in ds is challenging due to the intellectual disability which accompanies ds. |
2021-06-22 |
2023-08-13 |
Not clear |